Cerebrovascular accidents, or strokes, are a major cause of death and disability worldwide. There are two main types of strokes - ischemic strokes, which account for 80% of cases and are caused by blockage of blood flow to the brain, and hemorrhagic strokes, which make up the remaining 20% and result from bleeding in or around the brain. Hemorrhagic strokes can be further divided into primary intracerebral hemorrhages caused by bleeding within the brain tissue itself, subarachnoid hemorrhages caused by bleeding on the surface of the brain, and hemorrhages due to cerebral amyloid angiopathy. Risk factors, evaluation, management, and complications of hemorrhagic
Intracerebral hemorhage Diagnosis and managementRamesh Babu
About ICH - Diagnosis and management, Discussed the clinical presentation, evaluation, radiological features and management including recent guidelines
Chronic Stable Angina- Diagnosis & management
By Dr Awadhesh Kumar Sharma
Dr. Awadhesh kumar sharma is a young, diligent and dynamic interventional cardiologist. He did his graduation from GSVM Medical College Kanpur and MD in Internal Medicine from MLB Medical college jhansi. Then he did his superspecilisation degree DM in Cardiology from PGIMER & DR Ram Manoher Lohia Hospital Delhi. He had excellent academic record with Gold medal in MBBS,MD and first class in DM.He was also awarded chief ministers medal in 2009 for his academic excellence by former chief minister of UP Smt Mayawati in 2009.He is also receiver of GEMS international award.He had many national & international publications.He is also in editorial board of international journal- Journal of clinical medicine & research(JCMR).He is also active member of reviewer board of many journals.He is also trainee fellow of American college of cardiology. He is currently working in NABH Approved Gracian Superspeciality Hospital Mohali as Consultant Cardiologist.
Intracerebral hemorhage Diagnosis and managementRamesh Babu
About ICH - Diagnosis and management, Discussed the clinical presentation, evaluation, radiological features and management including recent guidelines
Chronic Stable Angina- Diagnosis & management
By Dr Awadhesh Kumar Sharma
Dr. Awadhesh kumar sharma is a young, diligent and dynamic interventional cardiologist. He did his graduation from GSVM Medical College Kanpur and MD in Internal Medicine from MLB Medical college jhansi. Then he did his superspecilisation degree DM in Cardiology from PGIMER & DR Ram Manoher Lohia Hospital Delhi. He had excellent academic record with Gold medal in MBBS,MD and first class in DM.He was also awarded chief ministers medal in 2009 for his academic excellence by former chief minister of UP Smt Mayawati in 2009.He is also receiver of GEMS international award.He had many national & international publications.He is also in editorial board of international journal- Journal of clinical medicine & research(JCMR).He is also active member of reviewer board of many journals.He is also trainee fellow of American college of cardiology. He is currently working in NABH Approved Gracian Superspeciality Hospital Mohali as Consultant Cardiologist.
Stroke is a medical emergency, with a mortality rate higher
than most forms of cancer. It is the second leading cause of
death in developed countries and is the most common cause
of serious, long-term disability in adults. The incidence of
stroke is increasing with the aging of populations and hence
there is a major challenge to health planners.
This is a short presentation at Down Town Hospital clinical meeting for DNB Medicine students. It dose not cover the all aspects of stroke care especially Thrombolysis, since it is difficult to practice for Medical specialist, and ischemic stroke is not common in North East India
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
Cerebral Hemorrhage By Arlyn M. Valencia, M.D. Associate Professor Of Neurology University Of Nevada School Of Medicine
1.
2. CEREBROVASCULAR ACCIDENT
OR ―BRAIN ATTACK‖
Third leading cause of death
750, 000 cases/year
Leading cause of significant disability
Cost: $40 billion/year
6. HEMORRHAGIC STROKE
The transformation of a bland infarct into a
hemorrhagic infarct is a common
occurrence (highest in autopsy studies)
―The concept of migratory embolus‖
9. Risk Factors For Hemorrhagic
Transformation of a Bland Infarct
Advanced age
Embolization as etiology
High systolic BP
CT shows mass effect
Larger territory strokes
Anticoagulation
History of coagulopathy
14. RISK FACTORS FOR ICH
Advancing age
HTN (autopsy studies on patients with ICH
showed high incidence of LVH;
PROGRESS – Perindopril Protection
Against Recurrent Stroke Study:76%
relative risk reduction of ICH in
comparison to placebo
Cigarette smoking
alcoholism
15. PRIMARY INTRACEREBRAL
HEMORRHAGE
Five most common sites:
putamen: 35 % - 50%
subcortical white matter 30%
thalamus: 10%-15%
pons 5%-12%
cerebellar white matter <5%
19. Most ICH originate from the rupture of
small deep penetrating arteries (50 to 200
um); most common: lenticulostriates
Same arteries are recognized to be
occluded in lacunar infarcts (process:
fibrinoid necrosis or lipohyalinosis)
28. SUBARACHNOID HEMORRHAGE
Accounts for 5-10% of all strokes
Incidence has not declined in 30 years
80% due to rupture of intracranial saccular
aneurysm
30-day mortality rate 50%
Most deaths occur within one week
29. RUPTURED ANEURYSM SITES: International
Cooperative Study On The Timing Of Aneurysm Study
Anterior communicating artery (ACom)
34%
ICA 30%
MCA 22%
Basilar tip, PICA, basilar trunk branches—
7.6%
30.
31.
32. CAUSES OF SUDDEN DEATH IN SAH
Large intraparenchymal hematoma
Destruction of brain tissue
Acute hydrocephalus
Increased intracranial pressure
Cardiac arrhythmias, MI, PE and
respiratory failure
33. LEADING CAUSES OF DEATH ON
HOSPITALIZED PATIENTS
Sequelae of initial hemorrhage
Recurrent aneurysmal
Vasospasm leading to ischemic stroke
Severe medical complications
36. CEREBRAL AMYLOID ANGIOPATHY
Amyloid deposition in the cerebral vessels
sufficient to cause symptomatic vascular
dysfunction
Vessel rupture and spontaneous ICH
untreatable and unpreventable
Prevalence of CAA: 2.3% age 65-74; 8%
age 75-84 ;12.1% 85 and older
37. HEMORRHAGE SECONDARY TO CEREBRAL
AMYLOID ANGIOPATHY (CAA)
Most common cause of lobar
hemorrhages in non-hypertensive
individuals
Elderly patients
Evidence of small microbleeds in MRI
Long-term recurrence increased
38. RISK FACTORS FOR CAA LOBAR
HEMORRHAGE
Advanced age
APOE epsilon2 or epsilon4
Alzheimer’s disease
39. RISK FACTORS FOR NON-CAA ICH
Family history of ICH
Frequent use of alcohol
Previous ischemic stroke
Low serum cholesterol level
40. ICH: EVALUATION AND WORK-UP:
History and PE
Computed Tomography (CT) scan of the head
12-lead EKG, chest X-ray
Complete blood count, PT, PTT
Chemistries (sodium, phosphate, glucose
abnormalities may mimic stroke)
Urine and serum toxicology (drugs and alcohol)
44. Under special circumstances, the
following tests may be required:
Cervical spine x-ray
Arterial blood gas
Lumbar puncture
Electroencephalogram (EEG)
45. Glasgow Coma Scale
1 2 3 4 5 6
Opens eyes in Opens eyes in
Does not open Opens eyes
Eyes response to response to N/A N/A
eyes spontaneously
painful stimuli voice
Utters Oriented,
Makes no Incomprehensibl Confused,
Verbal inappropriate converses N/A
sounds e sounds disoriented
words normally
Abnormal Flexion /
Makes no Extension to Localizes Obeys
Motor flexion to painful Withdrawal to
movements painful stimuli painful stimuli Commands
stimuli painful stimuli
46. Overview of ICH Management
ICH has frequent early, ongoing bleeding and
progressive deterioration, severe clinical deficits
and subsequent high mortality and morbidity
rates
Good general supportive management (airways,
oxygenation, circulation, glucose level, fever, DVT
prophylaxis)
Slowing or stopping initial bleeding
Blood removal from parenchyma or ventricles
Management of complications of blood in the rain
(increased ICP, decreased CPP)
47. CASE SPECIFIC MANAGEMENT
Correctible/controllable causes of
hemorrhage (e.g. warfarin)
Clipping of aneurysm
48. Herniation
Early clinical signs: mental status change,
pupillary dilatation, vomiting
Late clinical signs: ocular paresis,
decerebrate rigidity, coma and death
49. TREATMENT OF BRAIN
SWELLING
Cerebral perfusion pressure =MAP-ICP
Fluid Restriction (1200 ml /day/m2)
Controlled hyperventilation: 25 mm Hg
Mannitol, 0.25 mg/kg IV over 20 minutes; repeat PRN,
serum osmolality maintained in the range of 300-
320mOsm/l
Barbiturate coma, with ICP monitoring (subrachnoid bolt,
IV catheter or Camino catheter): maintain CPP greate
than 50 mmHg; pentobarbtial serum level of 2-4 mg/dl
Drainage of CSF (ventriculostomy)
Lobectomy
58. Intracerebral hemorrhage has
frequent early, ongoing
bleeding and progressive
deterioration, severe clinical
deficits and subsequent high
mortality and morbidity rates.