The document provides information about an activity to teach students about the central dogma of molecular biology. It includes puzzles and a pictionary game to engage students. Students will learn about DNA, RNA, proteins, their structures and functions. The activity aims to teach students how genetic information flows from DNA to RNA to proteins and how proteins are synthesized using mRNA codons.

3. ATTENDANCE

6. You are given a piece of
paper with a
questions/phrases in it,
and they need to find the
students whose holding the
other piece of paper with
an answer on it.

7. I'm
Puzzled?!
?

8. Each group will be
given a puzzle that
the students will need
to arrange and hold it
for the next activity.

9. I'm
Complete
Now!!!

10. After you complete the
puzzle flip it and you
will see a jumbled
letters, arrange it,
paste the picture at
the board and write
the word below it.

11. CENTRAL DOGMA
OF MOLECULAR
BIOLOGY

12. At the end of the lesson the
students should be able to:
• describe the building blocks
of DNA, RNA and proteins;
• differentiate the structural
and functional characteristics
of DNA and RNA;
• characterized the different
levels of protein structure
and
• apply and translate the given
coding sequences.

13. PICTIONARY

14. Pick a representative in
each group. The
representative will be
given a description and
he/she had to do is draw
the description, and the
rest of the group will
guess the word.

15. is a term used to
describe the physical
structure of DNA

16. is the structure of
the simplest type of
RNA

17. basic unit from which
something is built up

18. A functional group
characterized by a
phosphorus atom bonded
to four oxygen atoms
(three single bonds
and one double bond).

19. • Francis Harry Compton
Crick OM FRS (8 June 1916
– 28 July 2004) was an
English molecular
biologist, biophysicist,
and neuroscientist.
• The fundamental theory of
central dogma was
developed by Francis
Crick in 1958.
DNA → RNA → protein

20. • A nucleotide is the
basic building block of
nucleic acids (RNA and
DNA).
• A nucleotide consists
of a sugar molecule
(either ribose in RNA
or deoxyribose in DNA)
attached to a phosphate
group

22. • deoxyribonucleic acid
• it contains the genetic
information used in the
development and functioning
of all known living
organisms.
• mostly found in the
nucleus.
• double helix
• Adenine, Thymine, Guanine,
Cytosine

23. • Ribonucleic acid
• RNA helps in the
synthesis of proteins
in our body.
• single-stranded
• adenine, guanine,
cytosine, and uracil

26. • it provides the template for
protein synthesis during
translation.
• it carries the genetic code
from DNA during transcription,
in the form of triplets of
nucleotides called codons.

27. • usually found in the
ribosome.
• rRNAs combine with proteins
and enzymes in the
cytoplasm to form
ribosomes, which act as the
site of protein synthesis.

28. • transfer of amino acids during
protein synthesis.
• reads the genetic code during
translation.
• also act as adapters in the
translation of the genetic
sequence of mRNA into proteins.
Thus, they are also called
adapter molecules.

30. • Proteins are among the most
abundant organic molecules
in living systems and are
way more diverse in
structure and function than
other classes of
macromolecules.

32. • The simplest level of
protein structure, primary
structure, is simply the
sequence of amino acids in
a polypeptide chain.

33. • Refers to local folded
structures that form within a
polypeptide due to
interactions between atoms of
the backbone.

34. • Three dimensional folding
pattern of a protein due to
interactions between the R
groups of the amino acids that
make up the protein.

35. • The quaternary structure of
a protein is how its
subunits are oriented and
arranged with respect to one
another.

38. • Cells decode mRNAs by reading
their nucleotides in groups of
three, called codons.
• used to translate a genetic
code into a sequence of amino
acids.

42. Adenine(A) Thymine(T)
Cytosine(C) Guanine(G)
DNA
RNA
Adenine(A) Uracil(U)
Cytosine(C) Guanine(G)

43. 5' ATG CAT AGA TTA GGA TAT CCC AGA TAG 3'
5' UAC GUA UCU AAU CCU AUA GGG UCU AUC 3'

44. 5’ AUGCAUAGAUUAGGAUAUCCCAGAUAG 3’
N-Met-His-Arg-Leu-Gly-Tyr-Pro-Arg-C

45. 1) 5’ AAATCTATCGGGTCTATACCTTTAGGT 3’
2) 5’ GTAGCATCATCGTCCCCTCTGCTAGAT 3’

46. 5’ AAA TCT ATC GGG TCT ATA CCT TTA GGT 3’
5’ UUU AGA UAG CCC AGA UAU GGA AAU CCA 3’
mRNA
Proteins
5’ PHE ARG STOP PRO ARG TYR GLY ASN PRO 3’

47. 5’ GTA GCA TCA TCG TCC CCT CTG CTA GAT 3’
5’ UUU AGA UAG CCC AGA UAU GGA AAU CCA 3’
mRNA
Proteins
5’ HIS ARG SER SER ARG GLY ASP ASP LEU 3’

48. Directions: Using the template
below. Draw the structure of
the 4 structure of protein and
write it's characteristic.

49. Direction: Choose and write the letter
of the correct answer.

50. Direction: Choose and write the letter
of the correct answer.

51. Research
about DNA
replication
A S S I G N M E N T