Review worksheet covering IB Biology content in Mitosis, Cell Division, and Stem Cells (Topic 1.6)

1. IB Biology: Cell Division & Stem Cells Review NAME:
1. On the pie char, RIGHT, mark the approximate relative amount of
time spent in each of the stages of the cell cycle. Include interphase,
prophase, metaphase, anaphase, telophase and cytokinesis.
2. Outline the three stages of interphase (in order) and what happens
during each one?
3. List three processes that involve mitosis.
4. Describe how tumors (cancers) are formed—include the terms mutagen, oncogene, and metastasis:
5. Cytokinesis is part of the cell cycle but not part of mitosis. Differentiate between mitosis and cytokinesis,
including how cytokinesis differs between animal and plant cells:
6. In the space below, draw simple diagrams of the four stages of mitosis with two chromosomes. Briefly explain
the events occurring at each stage and label relevant structures.

2. 7. Differentiate between ‘sister chromatids’ and ‘chromosomes’.
8. Describe how to calculate the Mitotic Index of a tissue sample:
9. Outline the role of Cyclins in the cell cycle:
10. Outline the relationship between smoking and risk of lung cancer:
11. What is a stem cell?
12. Explain briefly how cell differentiation occurs. Refer to ‘genes’ in your answer.
13. Outline the therapeutic use of stem cells in reference to the following two diseases:
a. Stargardt’s disease:
b. Leukemia:
14. Describe the pros and cons of adult stem cells:
15. Describe the pros and cons of embryonic stem cells: