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Cell Division: Mitosis
GIDEON ROBERT UNIVERSITY
ANATOMY AND PHYSIOLOGY
NSWANA CHING’AMBU
Cell Division
• Know
• Cell life cycle
• What is cell division
• Importance of mitosis
• Overview of DNA replication
• Events of cell division
• What is mitosis
• Discuss stages of mitosis
Cell Life Cycle
• Cells have two major periods
1. Interphase
• Cell grows
• Cell carries on metabolic processes
2. Cell division
• Cell replicates itself
• Function is to produce more cells for growth
and repair processes
Cell Division
• Cell division is the process by which parent
cell divide to form daughter cells
• There are two types of cell division; mitosis
and meiosis
• Importance of cell division
•Formation of sex cells
•Growth of an organism
•Repair of damaged tissue of an organism
Overview of DNA Replication
• DNA replication is duplication of
DNA into two copies.
• Genetic material duplicated and
readies a cell for division into two
cells
• Occurs toward the end of interphase
• DNA uncoils and each side serves
as a template
Events of Cell Division
1. Mitosis
• Division of the nucleus
• Results in the formation of two daughter nuclei
2. Cytokinesis
• Division of the cytoplasm
• Begins when mitosis is near completion
• Results in the formation of two daughter cells
Mitosis
• Mitosis is the type of cell division in which the genetic
material is duplicated producing two daughter cells
that are genetically identical to parent cells
• Daughter cells maintain the diploid number of
chromosomes. Therefore, after mitosis each daughter
cell has 46 chromosomes
• Mitosis occur in somatic cells
• Mitosis is important for growth and repair of an
organism
Stages of Mitosis
1. Interphase
• Longest phase of cell life cycle
• No cell division occurs
• The cell carries out normal metabolic activity and growth
• At the end, DNA replication occurs producing two copies
Stages of Mitosis
2. Prophase
• First and longest phase of mitosis
• Chromatin condense into chromosomes
• Nuclear envelopes breaks down and nucleus disappear
• Nucleolus disassembles
• Centrioles migrate to the poles
Stages of Mitosis
3. Metaphase
• Mitotic spindles of centrioles attach to each pair of
sister chromatids at the centromere
• The pulling effect of spindles align sister chromatids at
the midline of the cell known as metaphase plate
Stages of Mitosis
4. Anaphase
• Mitotic spindles split sister chromatids at the
centromere into daughter chromosomes
• Daughter chromosomes are pulled to the opposite
poles of the cell
• The cell become elongated in readiness to split
Stages of Mitosis
5. Telophase
• Daughter nuclei begin forming around daughter
chromosomes on both ends of the cell
• A cleavage furrows form, where splitting of the cell takes
place
Stages of Mitosis
6. Cytokinesis
• Cytokinesis is the splitting of cytoplasm into two daughter
cells
• Each new cell is identical to the parent cell and contain
some genetic material
• Daughter cells have a diploid number, 46 chromosomes
Stages of Mitosis
Cell division Mitosis.pdf
Cell division Mitosis.pdf

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Cell division Mitosis.pdf

  • 1. Cell Division: Mitosis GIDEON ROBERT UNIVERSITY ANATOMY AND PHYSIOLOGY NSWANA CHING’AMBU
  • 2. Cell Division • Know • Cell life cycle • What is cell division • Importance of mitosis • Overview of DNA replication • Events of cell division • What is mitosis • Discuss stages of mitosis
  • 3. Cell Life Cycle • Cells have two major periods 1. Interphase • Cell grows • Cell carries on metabolic processes 2. Cell division • Cell replicates itself • Function is to produce more cells for growth and repair processes
  • 4. Cell Division • Cell division is the process by which parent cell divide to form daughter cells • There are two types of cell division; mitosis and meiosis • Importance of cell division •Formation of sex cells •Growth of an organism •Repair of damaged tissue of an organism
  • 5. Overview of DNA Replication • DNA replication is duplication of DNA into two copies. • Genetic material duplicated and readies a cell for division into two cells • Occurs toward the end of interphase • DNA uncoils and each side serves as a template
  • 6. Events of Cell Division 1. Mitosis • Division of the nucleus • Results in the formation of two daughter nuclei 2. Cytokinesis • Division of the cytoplasm • Begins when mitosis is near completion • Results in the formation of two daughter cells
  • 7. Mitosis • Mitosis is the type of cell division in which the genetic material is duplicated producing two daughter cells that are genetically identical to parent cells • Daughter cells maintain the diploid number of chromosomes. Therefore, after mitosis each daughter cell has 46 chromosomes • Mitosis occur in somatic cells • Mitosis is important for growth and repair of an organism
  • 8. Stages of Mitosis 1. Interphase • Longest phase of cell life cycle • No cell division occurs • The cell carries out normal metabolic activity and growth • At the end, DNA replication occurs producing two copies
  • 9. Stages of Mitosis 2. Prophase • First and longest phase of mitosis • Chromatin condense into chromosomes • Nuclear envelopes breaks down and nucleus disappear • Nucleolus disassembles • Centrioles migrate to the poles
  • 10. Stages of Mitosis 3. Metaphase • Mitotic spindles of centrioles attach to each pair of sister chromatids at the centromere • The pulling effect of spindles align sister chromatids at the midline of the cell known as metaphase plate
  • 11. Stages of Mitosis 4. Anaphase • Mitotic spindles split sister chromatids at the centromere into daughter chromosomes • Daughter chromosomes are pulled to the opposite poles of the cell • The cell become elongated in readiness to split
  • 12. Stages of Mitosis 5. Telophase • Daughter nuclei begin forming around daughter chromosomes on both ends of the cell • A cleavage furrows form, where splitting of the cell takes place
  • 13. Stages of Mitosis 6. Cytokinesis • Cytokinesis is the splitting of cytoplasm into two daughter cells • Each new cell is identical to the parent cell and contain some genetic material • Daughter cells have a diploid number, 46 chromosomes