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Bone health
8 million women and 2 million men in the US have osteoporosis. The document discusses the history of defining and diagnosing osteoporosis, controversies around commercialization and overdiagnosis, and natural ways to build strong bones versus pharmaceutical approaches and their risks. Key points include how the drug Fosamax was marketed and definitions were expanded, studies linking dairy and proton pump inhibitors to weaker bones, and natural bone-supporting nutrients like curcumin and vitamin D.
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Bone health
- 1. 8 million womenin the United States are currently diagnosed with osteoporosis 2 million men suffer from the disease 2013 Healthy Bones Healthy Life Osteoporosis Cause and Solution
- 2. Osteo Blasts(Build) Osteo Clasts (remove old bone) Produce RBC Support body Balance flexibility With Strength
- 3.
- 4. Healthy Discs = Movementand alignment and Canal
- 5. Gene 71 YO11 fractures/ 9 RX’s 95 YO no fractures/ no RX’s 81 YO no new fractures/ no RX’s
- 6. Osteoporosis 1992Rome Italy meeting for definition of osteoporosis World Health Organization how to diagnose and measure osteoporosis Doctors and researchers didn't even have a shared view of how osteoporosis should be defined. After 30 years old bone loss is normal so what is normal what is pathological Osteopenia was invented for researchers to use never was intended for a disease category Osteopenia natural thinning of the bone
- 7. The T-score youngnormal reference mean •The US standard is to use data for a thirty-year-old of the same sex and ethnicity •WHO recommends using data for a thirty-year-old white female for everyone The Z-score age-matched normal BMD of their age, sex, ethnicity. coexisting illnesses: glucocorticoid therapy Hyperparathyroidism alcoholism
- 8. 1995 MerckFosamax 1st non hormonal treatment (hormonal treatments caused Cancer) To increase sales had to get women to get a bone densitometer check $300 per test and only 200 machines in USA (expensive and inaccessible) Created and institution “Bone measurement institute” Non profit established by Merck headed by Jeremy Allen = no building only the non profit institute was his desk at Merck one way they profit from those drugs is to extend their use to as many people as possible, I.D. milder and milder versions of a disease Osteoporosis and Osteopenia Caleb Alexander, a pharmaco- epidemiologist at the University of Chicago
- 9. Merck Found cheepsmall measurements wrist, forearm, heals periphery scanners Peripheral machine are not accurate Dr. Sanford Bane pres international society for clinical Densitometry Merck bought a company to measure peripheral made machines at a very low price (then dissolved the company) Merck funded FDA studies for the smaller machines Merck got Medicare to pay for (bone mass medication act) 1997 1997 Merck got clearance from the FDA for a new version of its drug. "Merck developed a dose of Fosamax, a 5-milligram — a lower dose that was intended for use by women with osteopenia,“
- 10. Osteopenia becamea condition that was seriously considered for treatment 77,000 in 1994 1.5 million annually by 1999 34 million 2010 the sale of peripheral machines went up more than 500 percent over the same period of time. Thru testing and advertising a cultural consensus took hold
- 11. Fosamax The long-term useof osteoporosis drugs known as bisphosphonates can actually weaken bones by impairing their ability to heal, leading to fractures, according to a study ….from New York- Presbyterian Hospital/Weill Cornell Medical Center From RXLIST.COM The efficacy of FOSAMAX has been established in studies of two years' duration. The greatest increase in bone mineral density occurred in the first year with maintenance or smaller gains during the second year. Efficacy of FOSAMAX beyond two years has not been studied.
- 12. "MY LEG JUSTSNAPPED" "low impact" or "no impact" fractures occurring in women taking Fosamax long term •feeling the bone break before they hit the floor. •“I slipped and fell, but I really felt the bone snap before I went down It was like the bone broke and that is actually what caused me to fall.“ •A woman who was wading in water who was struck at thigh level by the wake of a small boat, causing the bone to snap.
- 13. Studies link Fosamaxto spontaneous bone fractures. •Women taking Fosamax are 125 times more likely to suffer a femur fracture from falls than women not taking the drug. •In 2008, the FDA contacted Fosamax manufacturer, Merck, about continuous reports linking Fosamax to femur fractures. •It took 16 months for Merck to add femur fractures to the list of potential side effects included on the drug package insert. •femur fractures •Osteomyelitis •inflammation of bone marrow •osteonecrosis of the jaw (ONJ), also known as dead jaw disease. •severe bone pain Merck continues to sell Fosamax
- 15. 1994 Consumption ofdairy products…was associated with an increased risk of hip fracture in old age. American Journal of Epidemiology. 1997 ....12 year long Harvard Nurses’ Health Study ...consumed the most calcium from dairy foods broke more bones than those who rarely drank milk •77,761 women aged 34 through 59 years of age. “These data do not support the hypothesis that higher consumption of milk or other food sources of calcium by adult women protects against hip or forearm fractures.” American Journal of Public Health Commercial Dairy Causes Osteoporosis India, Japan, and Peru average daily calcium intake less than a third of the U.S. the incidence of bone fractures is quite low.
- 16. Cortisol Thyroid Raises Cortisol •Low Thyroidfunction •Inflammation •Stress •Tissue Damage •Vaccinations •Toxic foods Lowers Thyroid •Estrogen •High Cortisol •Liver toxicity •Fluoride •Pesticides •Stress •Toxic foods •Medications •vaccinations Lowers Cortisol •Healthy Thyroid •Vegetables •Healthy Water Helps Thyroid •Healthy Gut •Low Cortisol •Healthy food •Healthy water •Low Stress Metabolic Balance Cortisol vs Thyroid
- 17. Cortisol Vital Short termvs Deadly Long term Higher and more prolonged levels of circulating cortisol •Impaired cognitive performance •Dampened thyroid function •Blood sugar imbalances •Decreased bone density •Sleep disruption •Decreased muscle mass •Elevated blood pressure •Lowered immune function •Slow wound healing •Increased abdominal fat Cortisol is a life sustaining adrenal hormone : •Blood sugar levels •Fat, protein and carbohydrate metabolism •Immune responses •Anti-inflammatory actions •Blood pressure •Heart and blood vessel tone •Central nervous system activation
- 18. older than65 in America broken a bone after age 50 health is “fair” or “poor” Smoke underweight for my height started menopause before age 45 have more than two drinks of alcohol several times a week sometimes fall not physically active Medical conditions: · Hyperthyroidism · Chronic lung disease · Cancer · Inflammatory bowel disease · Chronic hepatic or renal disease · Vitamin D deficiency · Cushing’s disease · Multiple sclerosis · Rheumatoid arthritis Medications: · Oral glucocorticoids (steroids) · Cancer treatments (radiation, chemotherapy) · Thyroid medicine · Antiepileptic medications · Gonadal hormone suppression ·Immunosuppressive agents Anti-acids, antidepressents, HTN, Risk factors for poor bone health
- 19. 2009 study donein India found that 500 mg of curcumin taken twice daily outperformed a commonly used non-steroidal anti-inflammatory drug (NSAID), alleviating pain and inflammation in rheumatoid arthritis. 2012 A randomized study to assess the efficacy and safety to curcumin in patients with active rheumatoid arthritis. Phytotherapy Research. NSAIDS •gastrointestinal bleeding, •increased blood pressure •accelerated osteoporosis •decreased production of blood cells •liver toxicity •eye toxicity •inhibit synthesis of cartilage create deficiencies in vital nutrients •folic acid •vitamin C •Calcium •iron.
- 20. •(2006). "Long-term ProtonPump Inhibitor Therapy and Risk of Hip Fracture". JAMA 296 (24): 2947–53 •"Antacids could lead to broken bones, study suggests". Canwest News Service August 12, 2008. Retrieved October 26, 2009 . •(2008). "Use of proton pump inhibitors and risk of osteoporosis-related fractures". Canadian Medical Association Journal 179 (4): 319–26 •(2009). "Bad to the bone: Acid stoppers appear to have a downside". Science News 171: 3. •(2010). "Proton pump inhibitors, fracture risk and selection bias: Three studies, same database, two answers". Osteoporosis International • (2012)Use of proton pump inhibitors and risk of hip fracture in relation to dietary and lifestyle factors: a prospective cohort study BMJ PPI Cause Osteoporosis
- 21. undeniable correlation offluoridation with osteoporosis and hip fracture in the elderly 1990 study of 541,000 cases of osteoporosis that found a definite connection between hip fractures in women over 65 and fluoride levels. JAMA. Bone Is Living Tissue. It is constantly being replaced with new cells, and having old cells removed. Bone building is a finely balanced, complicated process. Fluoride has been known to disrupt this process since the 1930s. •Osteoporosis • Hypothyroid •skeletal thinning, •Fractures • anemia • rickets •general arthritis •stomach pain •nausea •vomiting •bone spurs •bone inflammation •kidney fibrosis •dental fluorosis Other mineral contaminants like lead and strontium-90
- 22. -Congressional Record 21July 1976 -Chief chemist of the National Cancer Institute, Dr. Dean Burk A 1998 laboratory analysis done at Sequoia Analytical Labs in California showed very high concentrations of fluoride in the following foods: Dole pineapple, canned Snapple Coke Classic Hansen's soda Minute Maid orange juice Gerber strawberry juice for babies Amstel Lite beer Rice Dream Sunny Delight orange drink Pepsi
- 23. Doulton uses coconutshells. Active carbon is used for water treatment due to its adsorbing effect with respect to organic and health endangering chemicals Free silver ions (Ag+) have a toxic effect on micro-organisms even in relatively low concentrations. They have a highly fungicidal, bactericidal and algaecidel effect. Medical studies describe silver ions a catalyst that disable the enzymes that microorganisms depend on to "breathe Doulton mines only the finest and purest kieselguhr or diatom earth from kiesel algae (one celled algae) deposited on the bottom of geological lakes and lagoons millions of years ago. www.doultonusa.com
- 24. Food sources ofVitamin D Salmon, fresh wild 100 g cooked 600-1000 IU Salmon, farmed, 100g cooked 100 – 250 IU Mackerel 85 g cooked 388 IU Canned Tuna 85g 154 IU Shitaki mushrooms 100g fresh 100 IU Whole Milk 250ml 97 IU 15 minutes of bare arm & leg UV sun exposure in UK between May-Sept 3,000 – 20,000 IU Vitamin D •General good health •Growth •strong bones •muscle function •healthy immune system 90% vitamin D is made in the skin from sunlight
- 25. 1999 Vitamin Kintake and hip fractures in women: a prospective study. Am J Clin Nutr 2000 Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr 2003 Vitamin K intake and bone mineral density in women and men. Am J Clin Nutr •110 micrograms of vitamin K a day are 30 percent less likely to break a hip than women who get less than that •eating a serving of lettuce or other green, leafy vegetable a day cut the risk of hip fracture in half when compared with eating one serving a week Vitamin K2 =calcium regulation and bone formation •green leafy vegetables •broccoli, •brussels sprouts •dark green lettuce •collard greens •kale •Grass-fed organic animal products (eggs, butter, dairy) •fermented foods such as natto •vegetables fermented using a starter culture of vitamin K2-producing bacteria •Goose liver pâté •Certain cheeses = Brie and Gouda
- 26. Metabolism Anabolism = Constructivemetabolism Re-growth Repair Catabolism = Metabolic Breakdown , For energy burning aspect dismantling of structural proteins (starvation/Fat utilization) R>B=Health R<B=Disease
- 28. Exercise Detox Non-corporate Food Sunlight Vit D-3 , Vit K2, Strontium citrate •Strengthen muscles, tendons and ligaments, •Help bones become mineralized, dense and strong, •Increase lymphatic system circulation, •Improve efficiency of the immune system.
- 29. Sheri 60 yoNeck pain 10 years •5 Rx’s •Osteoporosis •Pain •HTN •Reflux
- 30. Proper nerve supply– FREE of Subluxation Regular Exercise Proper Nutrition Sufficient Rest Prayer and Meditation
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- 34.