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DIFFERENTIATION 
 Differentiation is the process by which an unspecialized 
cell (such as a fertilized egg cell), divides many times to 
produce specialized cells that work together and make up 
the body. 
 Every cell in the body was originated from a single 
fertilized egg, the zygote, that divides many times to 
produce an embryo. 
 Embryonic cells differentiate into many different cell types 
(250), from a new-born baby to an elderly adult. 
 A differentiated cell will develop specific structures and 
perform certain functions. 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Body Tissues 
 Tissues 
 Groups of cells with similar structure and 
function 
 Four primary types 
 Epithelial tissue (epithelium) 
 Connective tissue 
 Muscle tissue 
 Nervous tissue
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Body Tissues
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Body Tissues 
 Tissues 
 Groups of cells with similar structure and 
function 
 Four primary types 
 Epithelial tissue (epithelium) 
 Connective tissue 
 Muscle tissue 
 Nervous tissue
Epithelial Tissues 
 Locations 
 Body coverings 
 Glandular tissue 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
 Functions 
 Protection 
 Absorption 
 Filtration 
 Secretion
Epithelium Characteristics 
 Cells fit closely together and often form 
sheets 
 Regenerate easily if well nourished 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Epithelium Characteristics 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.17a
Classification of Epithelia 
 Number of cell layers 
 Simple—one layer 
 Stratified—more 
than one layer 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.17a
Classification of Epithelia 
 Shape of cells 
 Squamous 
 flattened 
 Cuboidal 
 cube-shaped 
 Columnar 
 column-like 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.17b
Simple Epithelia 
 Simple squamous 
 Single layer of flat cells (much wider than they are thick). 
(The thinnest tissue of the body). 
 Usually forms membranes 
 Lines body cavities, lungs and capillaries 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Simple Squamous Epithelia 
 Allows transport across membranes in lungs and capillaries, 
secretes fluid in serous membranes (pericardial and pleural), 
covers organs… 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.18a
Simple Epithelia 
 Simple cuboidal 
 Single layer of cube-like cells 
 Common in exocrine glands and their ducts 
 Forms walls of kidney tubules and covers the 
ovaries 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Simple Cuboidal Epithelia 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.18b
Simple Epithelia 
 Simple columnar 
 Single layer of tall cells 
 Often includes mucus-producing goblet cells 
or microvilli at surface for absortion. 
 Lines digestive tract. 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Simple Columnar Epithelia 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.18c
Simple Epithelia 
 Pseudostratified columnar 
 Single layer, but some cells are shorter than 
others. It often looks like a double layer of 
cells 
 Sometimes ciliated, such as in the respiratory 
tract 
 May function in absorption or secretion 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Simple Pseudostratified Epithelia 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.18d
Stratified Epithelia 
 Stratified squamous 
 Cells at the apical surface are flattened 
 Found as a protective covering where friction 
is common 
 Locations 
 Skin 
 Mouth 
 Esophagus 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Stratified Squamous Epithelia 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.18e
Glandular Epithelium 
 Gland 
 One or more cells responsible for secreting a 
particular product 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Glandular Epithelium 
 Two major gland types 
 Endocrine gland 
 Ductless secretions diffuse into blood 
vessels 
 All secretions are hormones 
 Exocrine gland 
 Secretions empty through ducts to the 
epithelial surface 
 Include sweat and oil glands 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Glandular Epithelium 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Body Tissues 
 Tissues 
 Groups of cells with similar structure and 
function 
 Four primary types 
 Epithelial tissue (epithelium) 
 Connective tissue 
 Muscle tissue 
 Nervous tissue
Connective Tissue 
 Found everywhere in the body 
 Functions 
 Binds body tissues together 
 Supports the body 
 Provides protection 
 Cells widely separated from each other in a matrix. 
 Extracellular matrix: Non-living material that 
surrounds living cells and is produced by them. 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Extracellular Matrix 
 Two main elements 
 Ground substance (mostly water with proteins 
and polysaccharides) 
 Fibers 
 Produced by the cells 
 Three types 
 Collagen (white) fibers 
 Elastic (yellow) fibers 
 Reticular fibers 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Connective Tissue Types 
 Bone (osseous tissue) 
 Cartilage 
 Dense connective tissue 
 Loose (Areaolar) Connective Tissue: 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
 Areaolar 
 Adipose 
 Reticular 
 Blood
Connective Tissue Types 
 Bone (osseous tissue) 
 Composed of 
 Bone cells (osteocytes) in lacunae 
(cavities) 
 Hard matrix of calcium salts 
 Used to protect and support the body 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Connective Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.19a
Connective Tissue Types 
 Cartilage 
 Composed of 
 Abundant collagen fibers and elastic 
fibers 
 Rubbery matrix 
 Chondrocytes 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
 Locations 
 Larynx, fetal skeleton, cushion-like discs 
between vertebrae, bronchi, nose, ears…
Connective Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.19b
Connective Tissue Types 
 Dense connective tissue (dense fibrous tissue) 
 Main matrix element is collagen fiber 
 Locations 
 Tendons—attach skeletal muscle to bone 
 Ligaments—attach bone to bone at joints 
 Dermis—lower layers of the skin 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Connective Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.19d
Connective Tissue Types 
 Loose connective tissue types 
 Adipose tissue 
 Matrix is an areolar tissue in which fat 
globules predominate 
 Many cells (adipocytes) contain large lipid 
deposits 
 Functions 
 Insulates the body 
 Protects some organs 
 Serves as a site of fuel storage 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Connective Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.19f
Connective Tissue Types 
 Blood (vascular tissue) 
 Blood cells surrounded by fluid matrix called 
blood plasma 
 Fibers are visible during clotting 
 Functions as the transport vehicle for 
materials 
 Formed elements 
– EErryytthhrrooccyytteess –red blood cells 
– LLeeuukkooccyytteess –white blood cells 
– PPllaatteelleettss -blood clotting 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Connective Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.19h
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Body Tissues 
 Tissues 
 Groups of cells with similar structure and 
function 
 Four primary types 
 Epithelial tissue (epithelium) 
 Connective tissue 
 Muscle tissue 
 Nervous tissue
Muscle Tissue 
 Function is to produce movement 
 Three types 
 Skeletal muscle 
 Cardiac muscle 
 Smooth muscle 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Muscle Tissue Types 
 Skeletal muscle 
 Under voluntary control 
 Contracts to pull on bones or skin 
 Produces gross body movements or facial 
expressions 
 Characteristics of skeletal muscle cells 
 Striated 
 Multinucleate (more than one nucleus) 
 Long, cylindrical (each cell is the length of 
the muscle) 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Muscle Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.20a
Muscle Tissue Types 
 Cardiac muscle 
 Under involuntary control 
 Found only in the heart 
 Function is to pump blood 
 Characteristics of cardiac muscle cells 
 Cells are attached to other cardiac muscle 
cells at intercalated disks 
 Striated 
 One nucleus per cell 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Muscle Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.20b
Muscle Tissue Types 
 Smooth muscle 
 Under involuntary muscle 
 Found in walls of hollow organs such as 
stomach, uterus, and blood vessels 
 Characteristics of smooth muscle cells 
 No visible striations 
 One nucleus per cell 
 Spindle-shaped cells 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Muscle Tissue Types 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.20c
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Body Tissues 
 Tissues 
 Groups of cells with similar structure and 
function 
 Four primary types 
 Epithelial tissue (epithelium) 
 Connective tissue 
 Muscle tissue 
 Nervous tissue
Nervous Tissue 
 Composed of neurons and nerve support cells 
 Sends impulses to other areas of the body 
 Irritability 
 Conductivity 
 Neurons and glial cells 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue 
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 3.21

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Body tissues 2014

  • 1. DIFFERENTIATION  Differentiation is the process by which an unspecialized cell (such as a fertilized egg cell), divides many times to produce specialized cells that work together and make up the body.  Every cell in the body was originated from a single fertilized egg, the zygote, that divides many times to produce an embryo.  Embryonic cells differentiate into many different cell types (250), from a new-born baby to an elderly adult.  A differentiated cell will develop specific structures and perform certain functions. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 2. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Body Tissues  Tissues  Groups of cells with similar structure and function  Four primary types  Epithelial tissue (epithelium)  Connective tissue  Muscle tissue  Nervous tissue
  • 3. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Body Tissues
  • 4. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Body Tissues  Tissues  Groups of cells with similar structure and function  Four primary types  Epithelial tissue (epithelium)  Connective tissue  Muscle tissue  Nervous tissue
  • 5. Epithelial Tissues  Locations  Body coverings  Glandular tissue Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings  Functions  Protection  Absorption  Filtration  Secretion
  • 6. Epithelium Characteristics  Cells fit closely together and often form sheets  Regenerate easily if well nourished Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 7. Epithelium Characteristics Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.17a
  • 8. Classification of Epithelia  Number of cell layers  Simple—one layer  Stratified—more than one layer Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.17a
  • 9. Classification of Epithelia  Shape of cells  Squamous  flattened  Cuboidal  cube-shaped  Columnar  column-like Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.17b
  • 10. Simple Epithelia  Simple squamous  Single layer of flat cells (much wider than they are thick). (The thinnest tissue of the body).  Usually forms membranes  Lines body cavities, lungs and capillaries Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 11. Simple Squamous Epithelia  Allows transport across membranes in lungs and capillaries, secretes fluid in serous membranes (pericardial and pleural), covers organs… Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.18a
  • 12. Simple Epithelia  Simple cuboidal  Single layer of cube-like cells  Common in exocrine glands and their ducts  Forms walls of kidney tubules and covers the ovaries Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 13. Simple Cuboidal Epithelia Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.18b
  • 14. Simple Epithelia  Simple columnar  Single layer of tall cells  Often includes mucus-producing goblet cells or microvilli at surface for absortion.  Lines digestive tract. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 15. Simple Columnar Epithelia Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.18c
  • 16. Simple Epithelia  Pseudostratified columnar  Single layer, but some cells are shorter than others. It often looks like a double layer of cells  Sometimes ciliated, such as in the respiratory tract  May function in absorption or secretion Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 17. Simple Pseudostratified Epithelia Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.18d
  • 18. Stratified Epithelia  Stratified squamous  Cells at the apical surface are flattened  Found as a protective covering where friction is common  Locations  Skin  Mouth  Esophagus Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 19. Stratified Squamous Epithelia Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.18e
  • 20. Glandular Epithelium  Gland  One or more cells responsible for secreting a particular product Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 21. Glandular Epithelium  Two major gland types  Endocrine gland  Ductless secretions diffuse into blood vessels  All secretions are hormones  Exocrine gland  Secretions empty through ducts to the epithelial surface  Include sweat and oil glands Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 22. Glandular Epithelium Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 23. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Body Tissues  Tissues  Groups of cells with similar structure and function  Four primary types  Epithelial tissue (epithelium)  Connective tissue  Muscle tissue  Nervous tissue
  • 24. Connective Tissue  Found everywhere in the body  Functions  Binds body tissues together  Supports the body  Provides protection  Cells widely separated from each other in a matrix.  Extracellular matrix: Non-living material that surrounds living cells and is produced by them. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 25. Extracellular Matrix  Two main elements  Ground substance (mostly water with proteins and polysaccharides)  Fibers  Produced by the cells  Three types  Collagen (white) fibers  Elastic (yellow) fibers  Reticular fibers Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 26. Connective Tissue Types  Bone (osseous tissue)  Cartilage  Dense connective tissue  Loose (Areaolar) Connective Tissue: Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings  Areaolar  Adipose  Reticular  Blood
  • 27. Connective Tissue Types  Bone (osseous tissue)  Composed of  Bone cells (osteocytes) in lacunae (cavities)  Hard matrix of calcium salts  Used to protect and support the body Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 28. Connective Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.19a
  • 29. Connective Tissue Types  Cartilage  Composed of  Abundant collagen fibers and elastic fibers  Rubbery matrix  Chondrocytes Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings  Locations  Larynx, fetal skeleton, cushion-like discs between vertebrae, bronchi, nose, ears…
  • 30. Connective Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.19b
  • 31. Connective Tissue Types  Dense connective tissue (dense fibrous tissue)  Main matrix element is collagen fiber  Locations  Tendons—attach skeletal muscle to bone  Ligaments—attach bone to bone at joints  Dermis—lower layers of the skin Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 32. Connective Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.19d
  • 33. Connective Tissue Types  Loose connective tissue types  Adipose tissue  Matrix is an areolar tissue in which fat globules predominate  Many cells (adipocytes) contain large lipid deposits  Functions  Insulates the body  Protects some organs  Serves as a site of fuel storage Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 34. Connective Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.19f
  • 35. Connective Tissue Types  Blood (vascular tissue)  Blood cells surrounded by fluid matrix called blood plasma  Fibers are visible during clotting  Functions as the transport vehicle for materials  Formed elements – EErryytthhrrooccyytteess –red blood cells – LLeeuukkooccyytteess –white blood cells – PPllaatteelleettss -blood clotting Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 36. Connective Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.19h
  • 37. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Body Tissues  Tissues  Groups of cells with similar structure and function  Four primary types  Epithelial tissue (epithelium)  Connective tissue  Muscle tissue  Nervous tissue
  • 38. Muscle Tissue  Function is to produce movement  Three types  Skeletal muscle  Cardiac muscle  Smooth muscle Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 39. Muscle Tissue Types  Skeletal muscle  Under voluntary control  Contracts to pull on bones or skin  Produces gross body movements or facial expressions  Characteristics of skeletal muscle cells  Striated  Multinucleate (more than one nucleus)  Long, cylindrical (each cell is the length of the muscle) Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 40. Muscle Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.20a
  • 41. Muscle Tissue Types  Cardiac muscle  Under involuntary control  Found only in the heart  Function is to pump blood  Characteristics of cardiac muscle cells  Cells are attached to other cardiac muscle cells at intercalated disks  Striated  One nucleus per cell Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 42. Muscle Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.20b
  • 43. Muscle Tissue Types  Smooth muscle  Under involuntary muscle  Found in walls of hollow organs such as stomach, uterus, and blood vessels  Characteristics of smooth muscle cells  No visible striations  One nucleus per cell  Spindle-shaped cells Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 44. Muscle Tissue Types Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.20c
  • 45. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Body Tissues  Tissues  Groups of cells with similar structure and function  Four primary types  Epithelial tissue (epithelium)  Connective tissue  Muscle tissue  Nervous tissue
  • 46. Nervous Tissue  Composed of neurons and nerve support cells  Sends impulses to other areas of the body  Irritability  Conductivity  Neurons and glial cells Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 47. Nervous Tissue Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 3.21