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Connective Tissues
 Connect epithelium to the rest of the body
(basal lamina)
 Provide structure (bone)
 Store energy (fat)
 Transport materials (blood)
 Have no contact with environment
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Characteristics of Connective Tissues
 Specialized cells
 Solid extracellular protein fibers
 Fluid extracellular ground substance
 The extracellular components of connective
tissues (fibers and ground substance) make up
the matrix
 Majority of tissue volume
 Determines specialized function
Matrix
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Ground Substance
 Is clear, colorless, and viscous
 Fills spaces between cells and slows
pathogen movement
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Classification of Connective Tissues
 Connective tissue proper
 Connect and protect
 Fluid connective tissues
 Transport
 Supportive connective tissues
 Structural strength
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Categories of Connective Tissue Proper
 Loose connective tissue
 More ground substance, less fibers
 For example, fat (adipose tissue)
 Dense connective tissue
 More fibers, less ground substance
 For example, tendons
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Connective Tissue Fibers
 Collagen fibers
 Most common fibers in connective tissue proper
 Long, straight, and unbranched
 Strong and flexible
 Resist force in one direction
 For example, tendons and ligaments
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Connective Tissue Fibers
 Reticular fibers
 Network of interwoven fibers (stroma)
 Strong and flexible
 Resist force in many directions
 Stabilize functional cells (parenchyma) and
structures
 For example, sheaths around organs
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Connective Tissue Fibers
 Elastic fibers
 Contain elastin
 Branched and wavy
 Return to original length after stretching
 For example, elastic ligaments of vertebrae
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Loose Connective Tissues
 The packing materials of the body
 Three types in adults
 Areolar
 Adipose
 Reticular
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Areolar Tissue
 Least specialized
 Open framework
 Viscous ground substance
 Elastic fibers
 Holds blood vessels and capillary beds
 For example, under skin (subcutaneous layer)
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Adipose Tissue
 Contains many adipocytes (fat cells)
 Types of adipose tissue
 White fat:
– most common
– stores fat
– absorbs shocks
– slows heat loss (insulation)
 Brown fat:
– more vascularized
– adipocytes have many mitochondria
– when stimulated by nervous system, fat break down
accelerates, releasing energy
– absorbs energy from surrounding tissues
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Adipose Tissue
 Adipose cells
 Adipocytes in adults do not divide:
– expand to store fat
– shrink as fats are released
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Reticular Tissue
 Provides support
 Complex, three-dimensional network
 Supportive fibers (stroma)
 Support functional cells (parenchyma)
 Reticular organs
 Spleen, liver, lymph nodes, and bone marrow
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Dense Connective Tissues
 Connective tissues proper, tightly packed with
high numbers of collagen or elastic fibers
 Dense regular connective tissue
 Dense irregular connective tissue
 Elastic tissue
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Dense Regular Connective Tissue
 Tightly packed, parallel collagen fibers
 Tendons attach muscles to bones
 Ligaments connect bone to bone and stabilize
organs
 Aponeuroses attach in sheets to large, flat
muscles
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Dense Irregular Connective Tissue
 Interwoven networks of collagen fibers
 Layered in skin
 Around cartilages (perichondrium)
 Around bones (periosteum)
 Form capsules around some organs (e.g., liver,
kidneys)
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Elastic Tissue
 Made of elastic fibers
 For example, elastic ligaments of spinal vertebrae
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Fluid Connective Tissues
 Blood and lymph
 Watery matrix of dissolved proteins
 Carry specific cell types (formed elements)
 Formed elements of blood
– red blood cells (erythrocytes)
– white blood cells (leukocytes)
– platelets
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Fluid Elements of Fluid Connective
Tissues
 Extracellular
 Plasma
 Interstitial fluid
 Lymph
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Lymph
 Extracellular fluid
 Collected from interstitial space
 Monitored by immune system
 Transported by lymphoid (lymphatic) system
 Returned to venous system
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Connective Tissues
 Fluid Tissue Transport Systems
 Cardiovascular system (blood)
 Arteries
 Capillaries
 Veins
 Lymphoid (lymphatic) system (lymph)
 Lymphatic vessels
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Supportive Connective Tissues
 Support soft tissues and body weight
 Cartilage
 Gel-type ground substance
 For shock absorption and protection
 Bone
 Calcified (made rigid by calcium salts, minerals)
 For weight support
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Supportive Connective Tissues
 Cartilage Matrix
 Proteoglycans derived from chondroitin sulfates
 Ground substance proteins
 Chondrocytes (cartilage cells) surrounded by
lacunae (chambers)
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Supportive Connective Tissues
 Cartilage Structure
 No blood vessels:
 Chondrocytes produce antiangiogenesis factor
 Perichondrium:
 Outer, fibrous layer (for strength)
 Inner, cellular layer (for growth and maintenance)
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Supportive Connective Tissues
 Types of Cartilage
 Hyaline cartilage
 Stiff, flexible support
 Reduces friction between bones
 Found in synovial joints, rib tips, sternum, and trachea
 Elastic cartilage
 Supportive but bends easily
 Found in external ear and epiglottis
 Fibrous cartilage (fibrocartilage)
 Limits movement
 Prevents bone-to-bone contact
 Pads knee joints
 Found between pubic bones and intervertebral discs
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Supportive Connective Tissues
 Bone or osseous tissue
 Strong (calcified: calcium salt deposits)
 Resists shattering (flexible collagen fibers)
 Bone cells or osteocytes
 Arranged around central canals within matrix
 Small channels through matrix (canaliculi) access
blood supply
 Periosteum
 Covers bone surfaces
 Fibrous layer
 Cellular layer
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

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A detailed description about the Connective Tissues

  • 1. Connective Tissues  Connect epithelium to the rest of the body (basal lamina)  Provide structure (bone)  Store energy (fat)  Transport materials (blood)  Have no contact with environment Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 2. Connective Tissues  Characteristics of Connective Tissues  Specialized cells  Solid extracellular protein fibers  Fluid extracellular ground substance  The extracellular components of connective tissues (fibers and ground substance) make up the matrix  Majority of tissue volume  Determines specialized function Matrix Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 3. Connective Tissues  Ground Substance  Is clear, colorless, and viscous  Fills spaces between cells and slows pathogen movement Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 4. Connective Tissues  Classification of Connective Tissues  Connective tissue proper  Connect and protect  Fluid connective tissues  Transport  Supportive connective tissues  Structural strength Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 5. Connective Tissues  Categories of Connective Tissue Proper  Loose connective tissue  More ground substance, less fibers  For example, fat (adipose tissue)  Dense connective tissue  More fibers, less ground substance  For example, tendons Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 6. Connective Tissues  Connective Tissue Fibers  Collagen fibers  Most common fibers in connective tissue proper  Long, straight, and unbranched  Strong and flexible  Resist force in one direction  For example, tendons and ligaments Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 7. Connective Tissues  Connective Tissue Fibers  Reticular fibers  Network of interwoven fibers (stroma)  Strong and flexible  Resist force in many directions  Stabilize functional cells (parenchyma) and structures  For example, sheaths around organs Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 8. Connective Tissues  Connective Tissue Fibers  Elastic fibers  Contain elastin  Branched and wavy  Return to original length after stretching  For example, elastic ligaments of vertebrae Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 9. Connective Tissues  Loose Connective Tissues  The packing materials of the body  Three types in adults  Areolar  Adipose  Reticular Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 10. Connective Tissues  Areolar Tissue  Least specialized  Open framework  Viscous ground substance  Elastic fibers  Holds blood vessels and capillary beds  For example, under skin (subcutaneous layer) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 11. Connective Tissues  Adipose Tissue  Contains many adipocytes (fat cells)  Types of adipose tissue  White fat: – most common – stores fat – absorbs shocks – slows heat loss (insulation)  Brown fat: – more vascularized – adipocytes have many mitochondria – when stimulated by nervous system, fat break down accelerates, releasing energy – absorbs energy from surrounding tissues Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 12. Connective Tissues  Adipose Tissue  Adipose cells  Adipocytes in adults do not divide: – expand to store fat – shrink as fats are released Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 13. Connective Tissues  Reticular Tissue  Provides support  Complex, three-dimensional network  Supportive fibers (stroma)  Support functional cells (parenchyma)  Reticular organs  Spleen, liver, lymph nodes, and bone marrow Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 14. Connective Tissues  Dense Connective Tissues  Connective tissues proper, tightly packed with high numbers of collagen or elastic fibers  Dense regular connective tissue  Dense irregular connective tissue  Elastic tissue Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 15. Connective Tissues  Dense Regular Connective Tissue  Tightly packed, parallel collagen fibers  Tendons attach muscles to bones  Ligaments connect bone to bone and stabilize organs  Aponeuroses attach in sheets to large, flat muscles Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 16. Connective Tissues  Dense Irregular Connective Tissue  Interwoven networks of collagen fibers  Layered in skin  Around cartilages (perichondrium)  Around bones (periosteum)  Form capsules around some organs (e.g., liver, kidneys) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 17. Connective Tissues  Elastic Tissue  Made of elastic fibers  For example, elastic ligaments of spinal vertebrae Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 18. Connective Tissues  Fluid Connective Tissues  Blood and lymph  Watery matrix of dissolved proteins  Carry specific cell types (formed elements)  Formed elements of blood – red blood cells (erythrocytes) – white blood cells (leukocytes) – platelets Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 19. Connective Tissues  Fluid Elements of Fluid Connective Tissues  Extracellular  Plasma  Interstitial fluid  Lymph Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 20. Connective Tissues  Lymph  Extracellular fluid  Collected from interstitial space  Monitored by immune system  Transported by lymphoid (lymphatic) system  Returned to venous system Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 21. Connective Tissues  Fluid Tissue Transport Systems  Cardiovascular system (blood)  Arteries  Capillaries  Veins  Lymphoid (lymphatic) system (lymph)  Lymphatic vessels Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 22. Supportive Connective Tissues  Support soft tissues and body weight  Cartilage  Gel-type ground substance  For shock absorption and protection  Bone  Calcified (made rigid by calcium salts, minerals)  For weight support Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 23. Supportive Connective Tissues  Cartilage Matrix  Proteoglycans derived from chondroitin sulfates  Ground substance proteins  Chondrocytes (cartilage cells) surrounded by lacunae (chambers) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 24. Supportive Connective Tissues  Cartilage Structure  No blood vessels:  Chondrocytes produce antiangiogenesis factor  Perichondrium:  Outer, fibrous layer (for strength)  Inner, cellular layer (for growth and maintenance) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 25. Supportive Connective Tissues  Types of Cartilage  Hyaline cartilage  Stiff, flexible support  Reduces friction between bones  Found in synovial joints, rib tips, sternum, and trachea  Elastic cartilage  Supportive but bends easily  Found in external ear and epiglottis  Fibrous cartilage (fibrocartilage)  Limits movement  Prevents bone-to-bone contact  Pads knee joints  Found between pubic bones and intervertebral discs Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
  • 26. Supportive Connective Tissues  Bone or osseous tissue  Strong (calcified: calcium salt deposits)  Resists shattering (flexible collagen fibers)  Bone cells or osteocytes  Arranged around central canals within matrix  Small channels through matrix (canaliculi) access blood supply  Periosteum  Covers bone surfaces  Fibrous layer  Cellular layer Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings