Bioinformatics is defined as the field that studies biology using computers and information technology. It involves the collection, storage, and analysis of molecular biological data using techniques from computer science and statistics. Some key events in bioinformatics include Watson and Crick proposing the DNA double helix structure in 1953, and the development of sequence alignment and structure prediction algorithms in the 1970s. Bioinformatics aims to better understand living cells at the molecular level by analyzing raw molecular sequence and structure data. It provides globally accessible databases and analysis tools to enable sharing and study of biological data.
INTRODUCTION
DEFINITION OF BIOINFORMATICS
HISTORY
OBJECTIVE OF BIOINFORMATIC
TOOLS OF BIOINFORMATICS
PROCEDURE AND TOOLS OF BIOINFORMATIC
BIOLOGICAL DATABASES
HOMOLOGY AND SIMILARITY TOOLS (SEQUENCE ALIGNMENT)
PROTEIN FUNCTION ANALYSIS TOOLS
STRUCTURAL ANALYSIS TOOLS
SEQUENCE MANIPULATION TOOLS
SEQUENCE ANALYSIS TOOLS
APPLICATION
CONCLUSION
REFERENCES
Bioinformatics is a hybrid science that links biological data with techniques for information storage, distribution, and analysis to support multiple areas of scientific research, including biomedicine.
An introduction to bioinformatics practices and aims will be given and contrasted against approaches from other fields. Most importantly, it will be discussed how bioinformatics fits into the discovery cycle for hypothesis driven neuroscience research.
INTRODUCTION
DEFINITION OF BIOINFORMATICS
HISTORY
OBJECTIVE OF BIOINFORMATIC
TOOLS OF BIOINFORMATICS
PROCEDURE AND TOOLS OF BIOINFORMATIC
BIOLOGICAL DATABASES
HOMOLOGY AND SIMILARITY TOOLS (SEQUENCE ALIGNMENT)
PROTEIN FUNCTION ANALYSIS TOOLS
STRUCTURAL ANALYSIS TOOLS
SEQUENCE MANIPULATION TOOLS
SEQUENCE ANALYSIS TOOLS
APPLICATION
CONCLUSION
REFERENCES
Bioinformatics is a hybrid science that links biological data with techniques for information storage, distribution, and analysis to support multiple areas of scientific research, including biomedicine.
An introduction to bioinformatics practices and aims will be given and contrasted against approaches from other fields. Most importantly, it will be discussed how bioinformatics fits into the discovery cycle for hypothesis driven neuroscience research.
INTRODUCTION
DEFINITION OF BIOINFORMATICS
HISTORY
OBJECTIVES OF BIOINFORMATICS
TOOLS OF BIOINFORMATICS
BIOLOGICAL DATABASES
HOMOLOGY AND SIMILARITY TOOLS (SEQUENCE ALIGNMENT)
PROTEIN FUNCTION ANALYSIS TOOLS
STRUCTURAL ANALYSIS TOOLS
SEQUENCE MANIPULATION TOOLS
SEQUENCE ANALYSIS TOOLS
APPLICATION
CONCLUSION
REFERENCES
An Introduction to Bioinformatics
Drexel University INFO648-900-200915
A Presentation of Health Informatics Group 5
Cecilia Vernes
Joel Abueg
Kadodjomon Yeo
Sharon McDowell Hall
Terrence Hughes
Slides for the afternoon session on "Introduction to Bioinformatics", delivered at the James Hutton Institute, 29th, 20th May and 5th June 2014, by Leighton Pritchard and Peter Cock.
Slides cover introductory guidance and links to resources, theory and use of BLAST tools, and a workshop featuring some common tools and tasks.
Bioinformatics Introduction and Use of BLAST ToolJesminBinti
Hi, I am Jesmin, studying MCSE. I think this file will help you if you want to know the basic information about Bioinformatics and the use of BLAST tool. The BLAST tool is the tool that matches the sequences of DNA,RNA and proteins.
INTRODUCTION
DEFINITION OF BIOINFORMATICS
HISTORY
OBJECTIVES OF BIOINFORMATICS
TOOLS OF BIOINFORMATICS
BIOLOGICAL DATABASES
HOMOLOGY AND SIMILARITY TOOLS (SEQUENCE ALIGNMENT)
PROTEIN FUNCTION ANALYSIS TOOLS
STRUCTURAL ANALYSIS TOOLS
SEQUENCE MANIPULATION TOOLS
SEQUENCE ANALYSIS TOOLS
APPLICATION
CONCLUSION
REFERENCES
An Introduction to Bioinformatics
Drexel University INFO648-900-200915
A Presentation of Health Informatics Group 5
Cecilia Vernes
Joel Abueg
Kadodjomon Yeo
Sharon McDowell Hall
Terrence Hughes
Slides for the afternoon session on "Introduction to Bioinformatics", delivered at the James Hutton Institute, 29th, 20th May and 5th June 2014, by Leighton Pritchard and Peter Cock.
Slides cover introductory guidance and links to resources, theory and use of BLAST tools, and a workshop featuring some common tools and tasks.
Bioinformatics Introduction and Use of BLAST ToolJesminBinti
Hi, I am Jesmin, studying MCSE. I think this file will help you if you want to know the basic information about Bioinformatics and the use of BLAST tool. The BLAST tool is the tool that matches the sequences of DNA,RNA and proteins.
RNA-seq for DE analysis: extracting counts and QC - part 4BITS
Part 4 of the training sesson 'RNA-seq for differential expression analysis' considers extracting the count table from a mapping, and performing QC to detect sample biases. See http://www.bits.vib.be
An introduction to the tools and methods used for the bioinformatics analysis of ChIP-Seq data.
Written and delivered for the "Epigenetics and its applications in clinical research" course at the Karolinska Institute in Stockholm, Sweden.
Next generation sequencing: research opportunities and bioinformatic challenges. A seminar I gave for the Computational Life Science (Univ. of Oslo) seminar series, March 2, 2011
AGRF in conjunction with EMBL Australia recently organised a workshop at Monash University Clayton. This workshop was targeted at beginners and biologists who are new to analysing Next-Gen Sequencing data. The workshop also aimed to provide users with a snapshot of bioinformatics and data analysis tips on how to begin to analyse project data. An introduction to RNA-seq data analysis was presented by AGRF Senior Bioinformatician Dr. Sonika Tyagi.
Presented: 1st August 2012
Course: Bioinformatics for Biomedical Research (2014).
Session: 4.1- Introduction to RNA-seq and RNA-seq Data Analysis.
Statistics and Bioinformatisc Unit (UEB) & High Technology Unit (UAT) from Vall d'Hebron Research Institute (www.vhir.org), Barcelona.
biotechnology and its applications
application s of biotechnology, bt.cotton, cloning, dna, dna fingerprinting, dna isolation, gene manipulation, genetic engineering, goldenrice., r dnatechnology, recombinant vaccines, transgenic, vectors
History and devolopment of bioinfomatics.ppt (1)Madan Kumar Ca
Dear Sir, Madam
Name: Madan Kumar C A
Topic: History and Development of Bioinformatics
Guide: Dr. Ramesh C K
Associate Professor
Dept of Biotechnnology
Sahyadri Science College
Shivamogga
Bioinformatics Course at Indian Biosciences and Research Instituteajay vishwakrma
Bioinformatics is the study of the inherent structure of biological information and biological systems. It brings together the avalanche of systematic biological data (e.g. genomes) with the analytic theory and practical tools of mathematics and computer science. Bioinformatics is a rapidly evolving and developing field both in terms of breadth of scope of useful applications and in terms of depth of what can be accomplished with the mission providing the training and knowledge in Bioinformatics IBRI has introduced the courses in Bioinformatics.
bioinformatics algorithms and its basicssofav88068
Introduction to bioinformatics, this is where u will learn about basic bioinformatics and its applications . what is bioinformatics and why bioinformatics. the basic fata sequences and blast algorithms. the examples of human genome , DNA , the genetic material and the blueprint of the whole existence. the concept of bioinformatics which is a relatively new field and the tools used there and the pipelines are also new . bioinformatics the lord the Saviour the Christ idk what else to write to up the discoverability score this is completely senseless and useless.SlideShare is a platform where you can upload, present, and discover presentations and infographics from various topics and industries. Please click the link in that email to verify your identity. To learn more, please visit our a and the long live the king of the pirates Luffy will find the one piece this website is totally crap pirate things that is best I've write 1000 words and it still isn't enough idk what else to add this .
INTRODUCTION
HISTORY
WHAT ARE THE DATABASE…?
WHY DATABASE….?
THE “PERFECT” DATABASE
IDENTIFIERS and ACCESSION NUMBER
TECHNICAL DESIGN
MAINTAINANCE OF BIOLOGICAL DATABASES..
GENERAL FEATURES
SOURCES OF BIOLOGICAL DATA…
DIFFERENT TYPES OF BIOLOGICAL DATABASE
FUNCTION
DATA ENTRY AND QUALITY CONTROL
AVAILIBILITY
APPLICATION
DATA RECORD AT THE YEAR 2004
CONCLUSION
REFFERENCES
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
The Art Pastor's Guide to Sabbath | Steve Thomason
Bioinformatics
1. 1
SIDDAGANGA INSTITUTE OF TECHNOLOGY
Department of Biotechnology
B.E. Biotechnology
Introduction to Bioinformatics
Mr. Vivek Chandramohan
Asst. Professor
Department of Biotechnology
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
2. WHAT IS BIOINFORMATICS?
Computer
Science
Statistics
BIOINFORMATICS
Molecular
Biology
Introduction to Bioinformatics 9/19/2014
2
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
3. DEFINITIONS
"Bioinformatics is the field of science in which biology,
computer science, and information technology merge into
a single discipline.”
-The National Center for
Biotechnology Information(2001) , NCBI
Introduction to Bioinformatics 9/19/2014
3
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
4. Introduction to Bioinformatics 9/19/2014
YEAR DISCOVERY/INVENTION AND ITS SIGNIFICANCE
1953
Watson and Crick proposed the DOUBLE HELIX structure of the genetic
material
1965
The first major bioinformatics project was undertaken by Margaret Dayhoff
in1965, who developed a first protein sequence database called Atlas of
Protein Sequence and Structure
1970
Brookhaven National Laboratory established the Protein Data Bank for
archiving three-dimensional protein structures
1970
The first sequence alignment algorithm was developed by Needleman and
Wunsch
1974
The first protein structure prediction algorithm was developed by Chou and
Fasman
1980
GenBank and the development of fast database searching algorithms such as
FASTA by William Pearson and BLAST by Stephen Altschul and coworkers.
4
TIME LINE
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
5. INTRODUCTION
Analyze, Store and Collect Molecular Biological
information from database
Main perspective of the field is the discovery of new
biological approaches
Provides central, globally accessible databases that
enable scientists to submit, search and analyze
information
Offers analysis software for data studies and
comparisons
Provides tools for modeling, visualizing, exploring and
interpreting data
Introduction to Bioinformatics 9/19/2014
5
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
6. GOALS
The ultimate goal of bioinformatics is to better understand
a living cell and how it functions at the molecular level
Analyzing raw molecular sequence and structural data,
bioinformatics research can generate new insights and
provide a “global” perspective of the cell.
Introduction to Bioinformatics 9/19/2014
6
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
7. WHY BIOINFORMATICS?
Number of researches increasing every day
Explosive growth in biological information
Need for a huge database to store, manage and retrieve
information
Regular updating
Available online to all
Without these most of the medical and biological field
would have been on standstill
Introduction to Bioinformatics 9/19/2014
7
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
8. WHY BIOINFORMATICS?
Introduction to Bioinformatics 9/19/2014
8
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
9. Introduction to Bioinformatics 9/19/2014
9
WHY BIOINFORMATICS?
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
10. FIELDS RELATED TO BIOINFORMATICS
Systems biology
Proteomics
Genomics
Pharmacogenomics
Pharmacogenetics
Cheminformatics
In silico ADME-Tox Prediction
Computational biology
Structural bioinformatics
Evolutionary relationships
Next generation Sequencing
(NGS)
Introduction to Bioinformatics 9/19/2014
10
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
11. APPLICATIONS
Introduction to Bioinformatics 9/19/2014
11
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
12. Introduction to Bioinformatics 9/19/2014
Top 3 Bioinformatics Companies by Revenue (2010-11)
Name of the Companies Location
Ocimum Biosolutions Hyderabad
Strand Life Sciences Bangalore
Geschickten Bangalore
70
60
50
40
30
20
10
0
2010-11 2009-10 2008-09
Biospectrum, Thursday, June 09, 2011
http://biospectrumindia.ciol.com/content/BioServices/11106093.asp
Ocimum Biosolutions
Strand Life Sciences
Geschickten
Revenue in crore
12
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka
13. Introduction to Bioinformatics 9/19/2014
13
Thank You
B.E. Biotechnology, Department of Biotechnology, SIT, Tumkur, Karnataka