Bacterial structures
and their functions
Iqbal Danish & fakiha javed
M.phil 1st Semester
Structures external to the cell
wall
Glycocalyx
Flagella
Pilli
Fimbrae
Capsule
Axial filament
Structures internal to cell wall
Cytoplasm
Cell membrane
Nucleus
Ribosomes
Inclusion bodies
Endospores
Mesosomes
Plasmid
Transposomes
Cell envelope
Lipopolysaccride
Techoic acid
Cell wall
 Cell wall is multilayer structure located external to
cytoplasm membrane
 Internally it is composed of peptidoglycan and external
structure vary according to the bacterial type
 Provide structural support t and maintain shape of cell
 Cell wall of acid fast bacteria have mycolic acid
 Sugar backbone with peptide side chains that are cross
linked
 Give rigid support, protect against osmotic pressure
flagella
Characteristics:
 Filamentous protein appendages attached to cell surface
 Have swimming movements incase of motile bacteria
 Have tactic behaviour(ability to move in response to
enviroment stimuli)
Composition
 Basal body
 Hook
 Long filament of polymerized protein called flagellin
Division on basis of locomotion
Polar(one area of cell)
Peritrichous(entire bacterial cell)
capsule
Characteristics:
 Bacteria produce or excrete high molecular weight of
polysaccride sugar coating called capsule
 Located outside the cell
Functions:
 Provide protection to bacteria from host
 Protect from phagocytosis
 Help in bacterial adhesion
Endospore
characteristics
 special structure formed by some bacteria(Bacillus,C
lostridium)
 Resistant to heat,chemicals,radiations and chemicals)
 Sporulation
 Spore to vegetative cycle
Pilli(fimbrae)
 Characteristics:
 Hair like filament short than flagella
 Composed of subunit of pillin
 Proteins are arranged in helical strand
 Mainly found in gram negative organisms
 Function:
 Attached to specific receptor
 Sex pilli(attachment)
Glycocalyx(slime layer)
Characteristics:
 Viscous,sticky,gelatinousPolysacchride coating external to
cell wall
 Adhere firmly to structres like skin,heart and catheter walls
 Important component of biofilm
Function:
 Adhesive property
 Antigenic sites
axial filament
characteristics:
 Bundle of fibrils
 Rotation of filament produce the movement
 Present in spirochetes
Structures internal to cell wall
Cytoplasm
 Thick,aqous,semitransparent and elastic material
 Contain ribosomes and various types of nutriental storage
granules
 About 80% water containing carbohydrates,proteins and
lipids
nucleus
 Consist of polyamine magnesium ions bond to negatively
charge circular super coiled double stranded DNA,small
amount of RNA and other proteins
 Cells genetic information which carries all the information's
requires for cell structures and function
 Purified nucleotides reveal that they composed of 60%
DNA 30% RNA 10% proteins by weight
plasmid
 Small circular non chromosomal double stranded DNA capable
of self replication
 Most frequently extra chromosomal but may become integrated
into bacterial DNA
 Function:
 Contain genes that confirm protective properties such as
antibiotics resistance are virulence factors are their own
transmissibility of other bacteria
 Plasmid play role in the lives of the organisms that have them
Types:
Episomes
Conjugate
colplasmid
Ribosomes
 Complex structure made of protein and RNA
 Shape of protein is determined by its amino acid sequence
 Risbosome present in cytoplasm loosly attach in plasma
membrane
 70S ribosome in prokaryotes,weight 2.7million
Inclusion bodies
 Several kind of deposits in cytoplasm
 Useful when enviroment is deficient
 Avoid osmotic pressure
 Metachromatic bodies use for storage
Mesosomes
 Structure invagination of plasma membrane
Two types
 Septal mesosomes
 Lateral mesosomes
 Functions:
 DNA replication
 Cell division
 secretion
Cytoplasmic membrane
 Composed of phospholipids bilayer
 Does not contain sterol
Cytochrome enzyme involved in electron transport and
oxidative phosporilation,lipids , enzymes and P binding
protein involved in cell wall biosynthesis
Function
 Selectively permeability and active transport
 Site of action of certain antibiotics such as polymixin
Transposomes
 Small piece of DNA that move bacteria rapidly from one
side to another between the DNA of the bacteria plasmid
and bacteriophage
 Also called jumping genes
Function:
 Code for antibiotic resistance and enzymes metabolic
enzymes and toxins
 May alter expression of neighboring genes are cause
mutation to genes into which they are inserted
Teichoic acid
 Are water soluble polymers containing a ribitole and
glycerol residue linked by phosphodiaster bonds
 Found in cell wall and is bonded to peptidoglycan
 Lipotechicacid is found in cell membrane and bounded to
membrane glycolipid in mesosomes specially
 Functions
 Important bacterial surface ,antigenic determinants
 It helps anchor the wall to membrane

Bacterial structures and their functions

  • 1.
    Bacterial structures and theirfunctions Iqbal Danish & fakiha javed M.phil 1st Semester
  • 2.
    Structures external tothe cell wall Glycocalyx Flagella Pilli Fimbrae Capsule Axial filament
  • 3.
    Structures internal tocell wall Cytoplasm Cell membrane Nucleus Ribosomes Inclusion bodies Endospores Mesosomes Plasmid Transposomes Cell envelope Lipopolysaccride Techoic acid
  • 4.
    Cell wall  Cellwall is multilayer structure located external to cytoplasm membrane  Internally it is composed of peptidoglycan and external structure vary according to the bacterial type  Provide structural support t and maintain shape of cell  Cell wall of acid fast bacteria have mycolic acid  Sugar backbone with peptide side chains that are cross linked  Give rigid support, protect against osmotic pressure
  • 5.
    flagella Characteristics:  Filamentous proteinappendages attached to cell surface  Have swimming movements incase of motile bacteria  Have tactic behaviour(ability to move in response to enviroment stimuli) Composition  Basal body  Hook  Long filament of polymerized protein called flagellin Division on basis of locomotion Polar(one area of cell) Peritrichous(entire bacterial cell)
  • 6.
    capsule Characteristics:  Bacteria produceor excrete high molecular weight of polysaccride sugar coating called capsule  Located outside the cell Functions:  Provide protection to bacteria from host  Protect from phagocytosis  Help in bacterial adhesion
  • 7.
    Endospore characteristics  special structureformed by some bacteria(Bacillus,C lostridium)  Resistant to heat,chemicals,radiations and chemicals)  Sporulation  Spore to vegetative cycle
  • 8.
    Pilli(fimbrae)  Characteristics:  Hairlike filament short than flagella  Composed of subunit of pillin  Proteins are arranged in helical strand  Mainly found in gram negative organisms  Function:  Attached to specific receptor  Sex pilli(attachment)
  • 9.
    Glycocalyx(slime layer) Characteristics:  Viscous,sticky,gelatinousPolysacchridecoating external to cell wall  Adhere firmly to structres like skin,heart and catheter walls  Important component of biofilm Function:  Adhesive property  Antigenic sites
  • 10.
    axial filament characteristics:  Bundleof fibrils  Rotation of filament produce the movement  Present in spirochetes
  • 11.
    Structures internal tocell wall Cytoplasm  Thick,aqous,semitransparent and elastic material  Contain ribosomes and various types of nutriental storage granules  About 80% water containing carbohydrates,proteins and lipids
  • 12.
    nucleus  Consist ofpolyamine magnesium ions bond to negatively charge circular super coiled double stranded DNA,small amount of RNA and other proteins  Cells genetic information which carries all the information's requires for cell structures and function  Purified nucleotides reveal that they composed of 60% DNA 30% RNA 10% proteins by weight
  • 13.
    plasmid  Small circularnon chromosomal double stranded DNA capable of self replication  Most frequently extra chromosomal but may become integrated into bacterial DNA  Function:  Contain genes that confirm protective properties such as antibiotics resistance are virulence factors are their own transmissibility of other bacteria  Plasmid play role in the lives of the organisms that have them Types: Episomes Conjugate colplasmid
  • 14.
    Ribosomes  Complex structuremade of protein and RNA  Shape of protein is determined by its amino acid sequence  Risbosome present in cytoplasm loosly attach in plasma membrane  70S ribosome in prokaryotes,weight 2.7million
  • 15.
    Inclusion bodies  Severalkind of deposits in cytoplasm  Useful when enviroment is deficient  Avoid osmotic pressure  Metachromatic bodies use for storage
  • 16.
    Mesosomes  Structure invaginationof plasma membrane Two types  Septal mesosomes  Lateral mesosomes  Functions:  DNA replication  Cell division  secretion
  • 17.
    Cytoplasmic membrane  Composedof phospholipids bilayer  Does not contain sterol Cytochrome enzyme involved in electron transport and oxidative phosporilation,lipids , enzymes and P binding protein involved in cell wall biosynthesis Function  Selectively permeability and active transport  Site of action of certain antibiotics such as polymixin
  • 18.
    Transposomes  Small pieceof DNA that move bacteria rapidly from one side to another between the DNA of the bacteria plasmid and bacteriophage  Also called jumping genes Function:  Code for antibiotic resistance and enzymes metabolic enzymes and toxins  May alter expression of neighboring genes are cause mutation to genes into which they are inserted
  • 19.
    Teichoic acid  Arewater soluble polymers containing a ribitole and glycerol residue linked by phosphodiaster bonds  Found in cell wall and is bonded to peptidoglycan  Lipotechicacid is found in cell membrane and bounded to membrane glycolipid in mesosomes specially  Functions  Important bacterial surface ,antigenic determinants  It helps anchor the wall to membrane