This document proposes a case study to monitor water quality in Vembanad Lake using remote sensing, modeling, and field observations. Vembanad Lake is an ecologically important water body in Kerala, India that has experienced increased pollution and disease outbreaks from development. The study aims to identify reservoirs of pathogenic vibrios like V. cholerae in the lake, understand their seasonal and spatial variation, and develop models to forecast disease outbreaks. Researchers will use remote sensing, field measurements, laboratory experiments, statistical modeling, and citizen science with local volunteers. The goals are to generate risk maps of outbreak areas, make recommendations to reduce pathogens and prevent disease, and engage communities through education programs.