Cardiac arrest is a medical emergency where the heart fails to pump blood effectively. It can be caused by cardiac or non-cardiac issues and requires immediate treatment to potentially reverse it, including cardiopulmonary resuscitation (CPR) and defibrillation. CPR involves chest compressions and rescue breathing to manually circulate blood and oxygen through the body until spontaneous circulation is restored. The appropriate treatment depends on the underlying heart rhythm, with shockable rhythms like ventricular fibrillation treated with defibrillation.
Mechanical Ventilation (MV) is almost always a challenging topic for ICU nurses and practitioners. In this presentation we are going to review and relearn basics of MV together.
comprehensive presentation on 2D echo use in ICu set up. helpful in finding causes of shock and also in monitoring of fluid status in critically ill patients.
Mechanical Ventilation (MV) is almost always a challenging topic for ICU nurses and practitioners. In this presentation we are going to review and relearn basics of MV together.
comprehensive presentation on 2D echo use in ICu set up. helpful in finding causes of shock and also in monitoring of fluid status in critically ill patients.
Mechanical Ventilation of Patient with COPD ExacerbationDr.Mahmoud Abbas
Mechanical Ventilation of Patient with COPD Exacerbation lecture presented by Dr Andres Esteban at the Egyptian Critical care Summit 2015 held at Cairo, egypt.
The Egyptian Critical Care Summit is the leading medical event and exhibition for Intensive Care Medicine in Egypt.
An excellent tool to treat refractory hypoxia. Target audience are ICU junior physicians and Respiratory Therapists. It will take away the fear of "What is APRV?" from your hearts and you will feel ready to give it a try.
Mechanical Ventilation of Patient with COPD ExacerbationDr.Mahmoud Abbas
Mechanical Ventilation of Patient with COPD Exacerbation lecture presented by Dr Andres Esteban at the Egyptian Critical care Summit 2015 held at Cairo, egypt.
The Egyptian Critical Care Summit is the leading medical event and exhibition for Intensive Care Medicine in Egypt.
An excellent tool to treat refractory hypoxia. Target audience are ICU junior physicians and Respiratory Therapists. It will take away the fear of "What is APRV?" from your hearts and you will feel ready to give it a try.
Cardiac capability improvement in cardiac rehabSubodh Gupta
ReLiva is dedicated to provide high quality comprehensive physiotherapy services to patients. This document details the cardiac rehabilitation program of ReLiva Physio and the benefits to the patients after cardiac events like myocardial infarction (MI), CABG, aortic valve replacement (AVR), angioplasty, chronic heart failure (CHF) and others. More information at www.reliva.in
in this topic the technique of chest physiotherapy, indications, contradications of chest physiotherapy are explained. different positions used in postural drainage are briefed.
if a person sudely collapses in front of you. what should we do?
immediately we should assess for cadiac arrest.
if so, immediately we should start high quality CPR.
This slide focuses on how to assess for cardiac arrest and how to do CPR.
Advanced cardiac life support or advanced cardiovascular life support (ACLS) refers to a set of clinical interventions for the urgent treatment of cardiac arrest, stroke and other life-threatening medical emergencies, as well as the knowledge and skills to deploy those interventions.
Similar to Als, cardiac arrest ghanem @@@Cardiology 2014 (20)
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
4. Cardiac arrest, also known as
cardiopulmonary arrest or circulatory
arrest, is the end of normal circulation of the
blood due to failure of the heart to contract
effectively.
Also referred as a sudden cardiac arrest
(SCA).
Cardiac arrest is a medical emergency that, in
certain situations, is potentially reversible if
treated early.
Unexpected cardiac arrest sometimes leads to
death almost immediately; this is called
sudden cardiac death (SCD).
5.
6. Based upon the ECG rhythm
1. SHOCKABLE
The two shockable rhythms are ventricular
fibrillation and pulseless ventricular
tachycardia
2. NON-SHOCKABLE
The two non–shockable rhythms are asystole
and pulseless electrical activity
9. Non-cardiac:
The most common non-cardiac causes:
Trauma
non-trauma related bleeding (such as
gastrointestinal bleeding, aortic rupture,
and intracranial hemorrhage)
Overdose
Drowning
12. Absence of palpable pulse.(The main
diagnostic criterion to diagnose a cardiac
arrest is lack of circulation: Lack of carotid
pulse is the gold standard for diagnosing
cardiac arrest).
Lack of consciousness.
Abnormal or absent breathing.
“silent chest”
Death.
N.B: Misdiagnosis may lead
to………………!!!!!!!
13.
14.
15. Delay Can Be Deadly
Patient delay is the biggest
cause of not getting care
fast.
Do not wait more than a few
minutes—
5 at the most
28. Ventricular Fibrillation (VF)
What VF looks like on an EKG
Shock “converts” VF to better rhythm
Defibrillation (electrical shock) is
the primary solution (cannot be
used in other lethal heart rhythms)
40. delayed endotracheal intubation combined
with passive oxygen delivery and minimally
interrupted chest compressions was
associated with improved neurologically intact
survival after out-of-hospital cardiac arrest in
patients with witnessed VF/VT
When an advanced airway (eg, endotracheal
tube or supraglottic airway) is placed, 2
providers no longer deliver cycles of
compressions interrupted with pauses for
ventilation.
1 breath every 6-8 seconds (8-10 breaths per
minute)
49. OTHER…..
1. OXYGEN ADMINISTRATION SET
2. LARYNGOSCOPE WITH DIFFERENT
SIZE
3. I.V. INFUSION SET, CUT DOWN SETS
AND IV FLUIDS
4. CARDIAC MONITOR WITH
DEFIBRILLATOR
5. MECHANICAL VENTILATOR
6. TRACHEOSTOMY SET
7. GAUZE COTTON ETC.
8. STERILE SYRINGES AND NEEDLES.
54. Elbows should be locked and
arms are straight.
Rescuer’s shoulders position
directly over hands.
Begin compression.
Pressure should come from
the shoulders.
Compression should depress
victim’s sternum
approximately 1.5- 2 inches.
Don’t allow the fingers to
touch the chest wall.
Allow chest to rebound to
normal position after each
compression.
55. Approach safely
Check response
Shout for help
Open airway
Check breathing
30 chest compressions
2 rescue breaths
SHOUT FOR
HELP
56. Approach safely
Check response
Shout for help
Open airway
Check breathing
30 chest compressions
2 rescue breaths
OPEN AIRWAY
58. Approach safely
Check response
Shout for help
Open airway
Check breathing
30 chest compressions
2 rescue breaths
CHECK
BREATHING
59. Look, listen and feel
for NORMAL
breathing
Do not confuse
agonal breathing
with NORMAL
breathing
CHECK
BREATHING
60. AGONAL
BREATHING
Occurs shortly after the heart stops in
up to 40% of cardiac arrests
Described as barely, heavy, noisy or
gasping breathing
Recognise as a sign of cardiac arrest
Erroneous information can result in
withholding CPR from cardiac arrest
victim
61. Approach safely
Check response
Shout for help
Open airway
Check breathing
30 chest
30 CHEST
COMPRESSIONS
c2 oremscpuer ebsresaitohsns
62. • Place the heel of one
hand in the centre of
the chest
• Place other hand on
top
• Interlock fingers
• Compress the chest
– Rate 100 min-1
– Depth 4-5 cm
– Equal compression :
relaxation
• When possible change
CPR operator every 2
min
CHEST
COMPRESSIONS
64. WHEN TO STOP
CPR
SPONTANEOUS signs of circulation are
restored.
TURNED over to medical services or
properly trained and authorized personnel.
OPERATOR is already exhausted &
cannot continue CPR.
PHYSICIAN assumes responsibility
(declares death, take over etc)----------
(DNAR???)
67. Neonatal Resuscitation
The etiology of neonatal arrests is nearly
always asphyxia.
Therefore, the A-B-C sequence has been
retained for resuscitation of neonates unless
there is a known cardiac etiology.
Rate:(30:2), to be changed to (15:2) if 2
rescuers.
78. AIRWAY, BREATHING
Appropriate sized ventilation bag on bed
Oxygen ready: humidified oxygen for pediatric
patients
Suction on and ready
Appropriate size suction catheters available
Airway equipment checked and at bedside –
estimate ETT size for children
Rapid sequence intubation tray at bedside
End tidal CO2 assessment equipment at
bedside
Pulse oximeter at bedside and ready
79. CIRCULATION
Manual and automatic BP cuffs at bedside
CPR backboard – available as needed
Heat lamps – available as needed
Intravenous lines stripped
ACLS drugs – available as needed
Appropriate size infusion catheters – available
as needed
Cardiac monitor on and event recording ready
Defibrillator on: appropriate size paddles [peds,
adult, internal] – external pacer pads
Call for blood if needed
80. MISCELLANEOUS
Bedside hematocrit and glucose
monitors
Appropriate size foley catheter –
available as needed
Appropriate size NG tube – available
as needed
81. Drugs used commonly
during resuscitation
Epinephrine (Adrenaline)
Amiodarone
Lidocaine (Lignocaine)
Magnesium Sulphate
(No role: Atropine, Ca++, Na
bicarbonate)
82.
83. Don’t Forget
• Push hard (at least 2 inches).
• Push fast (at least 100/min).
• Minimize interruptions in compressions.
• Compress to ventilation: 30:2
• Defibrillate as soon as possible.
• ETT (8 – 10 breath/min).
• Encourage team resuscitation.
• New 5th link in the chain of survival
(post cardiac arrest care).
85. Forget
Look, Listen and Feel victims before
starting CPR.
Atropine in ACLS.
Routine use of calcium.
Routine use of sodium bicarbonate
(Except in cases of cardiac arrest due
to hyperkalemia or TCA poisoning).