Acute rheumatic fever is an autoimmune disease that occurs after a streptococcal throat infection. It causes inflammation in connective tissues and blood vessels in joints and the heart. Symptoms include arthritis, heart issues like valve damage, and involuntary movements. Treatment involves antibiotics to eliminate streptococcus, medications for pain and inflammation, bed rest, and potentially heart valve replacement for severe cases. Long term prevention requires continued antibiotics to avoid recurrent bouts of the disease.