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13. Implants in Young Children and Adolescents
                                                     Arun Sharma DDS
                         Department of Preventive and Restorative Dentistry
                                    UCSF School of Dentistry
                                             John Beumer III DDS, MS
            Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry
                                               UCLA School of Dentistry
     This program of instruction is protected by copyright ©. No portion of this program of instruction
     may be reproduced, recorded or transferred by any means electronic, digital, photographic,
     mechanical etc., or by any information storage or retrieval system, without prior permission.
Objectives
!  Present some guidelines for implant therapy in children
Issues
!  Should  Implants should be
   placed in children?
!  If so, which patients?
!  At what age should
   implants be placed?
Implants in Young Children and Adolescents
Our Primary Concern with Implant Placement is Growth
!   The    newborn lacks pronounced alveolar ridges
!     Maxillary vertical development comes with developing tooth buds and
      the formation and eruption of teeth
!     The maxilla comes down and forward secondary to sutural apposition
      and with downward and forward growth of the alveolar process
      associated with the eruption of primary and permanent teeth
!     Growth of the mandible is not dependent on the presence of teeth
Implants in Young Children and Adolescents
Growth
 !   Inthe absence of maxillary teeth the alveolar ridges do not develop
     and the maxilla will be underdeveloped sagitally and vertically

 !   Mandibular growth is not dependent on the presence of teeth

 !   Therefore, in the presence of anadontia or hypodontia the
     relationship between the maxilla and mandible is disproportionate with
     most patients developing Class III relationships
Implants in Young Children and Adolescents
Growth
  !    Implants do not change position with growth and do not move
       vertically with alveolar development (Odman et al, 1991, Sharma
       and Vargervik , 2006)

  !    Implants placed in the anterior portions of the maxilla and mandible
       do not affect transverse growth of these structures (Thilander et
       al, 1992)
Partial or Complete Anadontia
          Patient Classification (Sharma and Vargervik, 2006)
!   Group   I – Children congenitally missing one tooth with adjacent
      permanent teeth
!     Group II – Children missing multiple teeth but with permanent teeth
      adjacent to edentulous sites
!     Group III – Children who are completely edentulous in one arch or
      have one or two teeth in undesirable positions
Group I   – Children congenitally missing one tooth with adjacent permanent teeth
Cleft lip and palate patients with single tooth defects secondary to partial anadontia

                                        Cleft                      Partial Anadontia




        Partial Anadontia
Group I – Children congenitally missing one tooth with adjacent permanent teeth
                    Dentition in Cleft Patients

                       !   Missing  Lateral
                           Incisors – 40%
                       !   Supernumerary
                           Lateral Incisors– 7%
                       !   Hypodontia – 50%
Group I – Children congenitally missing one tooth with adjacent permanent teeth
             Management of the Missing Lateral Incisor in Clefts
Implants - Issues
    ! Growth - Skeletal Development
       !   Dental alveolar

       !   Mandible and maxilla

       ! It is advisable to wait until two consecutive
           cephalometric films one year apart show no
           evidence of growth
    ! Site development
       !   Horizontal and vertical deficiencies usually present    Courtesy A Sharma
Group I – Children congenitally missing one tooth with adjacent permanent teeth
Note: Gingival
contours are not
quite normal

Why?
Scarring
                                                                           Courtesy A Sharma
associated with
the closure and
grafting the cleft   Consequences: None. Almost all cleft patients have a low smile line.
Group I – Children congenitally missing one tooth with adjacent permanent teeth
           Management of the Missing Lateral Incisor in Clefts
Implants - Issues
  !   Consequences of early placement
   !   Implant will be submerged relative to the adjacent
       teeth with the attendant esthetic consequences
   !   Less favorable implant biomechanics ie. crown

       root ratios
                                                                 Courtesy A Sharma
Note gingival contours. These are to be
expected given the scarring secondary to
the multiple surgical procedures necessary
to close and graft the cleft.

    UCSF Data (Sharma and Vargervik, 2006)                  Courtesy A Sharma


!   24 patients (15 male, 9 female)      !   33 implants placed
!   9 bilateral clefts                   !   31 implants restored
!   15 unilateral clefts                 !   28 still in function
Grafting the Cleft and Placing the Implants
                               Average age in years
!   Alveolar   cleft bone graft - 14.3
     !  Range   (12 – 26) Median 15

!   Implant   Placement - 18.1
     !  Range   (14 – 28) Median 19
Group I – Children congenitally missing one tooth with adjacent permanent teeth
  Most clefts present with either horizontal or
  vertical bone deficiencies and require
  grafting prior to implant placement

    Implant Placement n = 33
    !   Adequate  bone 15 (45.4%)
    !   Need for regraft 18 (54.6%)
Results
!    Implants placed   -     33    *2 implants failed at 2nd stage

!    Implants restored -     31    *2 failed in a bilateral cleft after 4 years


!    Implants in function - 28     *1 failed in a unilateral cleft after 11 years
Follow up Time (months)
!   Time   since placement - 133.6 mths
     (Range 85 – 166. Median 130)


!   Time   since restored - 129 mths
     (Range 74 – 158, Median 121)
Summary 2006 Data (Sharma and Vagervik, 2006)

!  Dental Implants can be      !  Dental implants placed in grafted
   successfully placed in         alveolar clefts can be successfully
   grafted alveolar clefts –      restored and loaded – 90.3%
   93.9 %                        !   2 implants lost in one patient after 4 yrs
                                 ! 1 implant lost after 11 years
UCSF Protocol (Sharma and Vargervik, 2006)
!    Expand maxilla orthodontically (7 – 8 years)
!    Close oro-nasal defect by grafting alveolar cleft (9 – 12 years)
!    Guide cuspid into arch and maintain space for lateral
!    If inadequate bone then regraft
!    Place implant to replace lateral incisor (after growth is
     completed 15 – 19 years)
Implants for those congenitally missing one tooth with adjacent
                        permanent teeth secondary to partial anadontia
              Issues
Orthodontics
!   Diastemas closed
!   Occlusion
       !    Anterior guidance
!  7   mm between the root surfaces
         of the adjacent teeth
Site enhancement
!   Horizontal       and vertical deficiencies
Implants for those congenitally missing one
tooth with adjacent permanent teeth secondary
              to partial anadontia
•  Consolidate the arch segments before implant placement
             14 y/o
                               19 y/o
Timing for Implant Placement

Lateral cephalograms, taken one year apart
demonstrating no dento-alveolar change
Implants for the patient with missing lateral incisors
Distance
between roots
!  7   mm

Avoid small
diameter
implants
Implants for the patient with missing lateral incisors
Implants for the patient with missing lateral incisors
Issues
•  Avoid small diameter
      implants
•  Implant position and
      angulation
•  Surgical templates
•  Gingival contours
•  Anterior guidance
•  Screw retention
Implant position                      Surgical Placement
  •  Screw access channel should exit through the cingulum (arrow)
  •  Head of the implant should be 2-4 mm below the proposed CEJ



                                                                     2-4 mm
This implant has been placed to     Implant positioning
  far beneath the gingiva.
                                              Result: The depth
                                              of the peri-implant is
                                              excessive leading to
                                              an increased risk of
                     Attachment               peri-implantitis and
                     level                    progressive bone
                                              loss around the
                      Gingival                implant.
                      margin
                                  30 months
                                     later                             Avoid labial inclinations
Implant positioning




Custom abutments - Labially inclined implants
Implants for the patient with missing lateral incisors
Implants for the patient with missing lateral incisors
                Brother – implant
                 placed at age 18
                 yrs 6 mths



                Sister – implant
                  placed at age 16
                  yrs 2 mths
Implants in Patients with Ectodermal Dysplasia and Nonsyndromic Forms of Partial Anadontia




Group II – Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
Group III – Children who are completely edentulous in one arch or have one or two teeth in
                 undesirable positions
Heriditary Ectodermal Dysplasia
!  Inherited: 1 in 100,000 live births
!  Many variants
!  Ectodermal tissues affected
      !   Hair
      !   Nails
      !   Teeth
      !   Sweat Glands
Ectodermal Dysplasia
Dental Problems
!   Unpredictable tooth eruption and loss
!   Poorly shaped crowns and roots
!   Defective enamel formation
!   Lack of alveolar development with
       closed vertical dimension of
       occlusion
!   Class III jaw relation
!   Prosthodontic challenges
    !   Group II vs Group III
Group II - Children missing multiple teeth but with permanent teeth adjacent
                            to edentulous sites

                                     –
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
                                     Implants - Advantages
!   Improved     stability, retention
      and support
!     Improved mastication
      efficiency
!     Preservation of residual
      tissues
     !    Remaining teeth
     !    Bone
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
Issues
  – Orthodontic care
     • Consolidate
       permanent dentition
       and the edentulous
       spaces
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
Issues
   !   Growth and timing of
       implant placement
   !   Prefer to wait until
       growth is completed
     !   Implants
                can be considered
      prior to completion of growth
      but the patient and family
      must recognize that the
      restoration is provisional
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
Issues
   – Retention of residual
     permanent dentition
     •  Permanent and deciduous
        dentition are often used to
        support provisional
        restorations
     •  Permanent dentition may be
        sacrificed at a later date in
        order to idealize the position
        and arrangement of implants
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
Issues
   – Interocclusal space
     •  Even when patients retain
        some permanent dentition
        there may be excessive
        interocclusal space
     •  The vertical dimension of
        occlusion must be restored if
        facial height and an a
        favorable esthetic result
        obtained
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
Issues
   !   Orthognathic surgery
   !   Occlusal plane
   !   Fixed vs removable
     !   Lack of maxillary
         development favors
         removable in the
         maxilla
     !   In the mandible fixed is

         generally favored
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
!  Early implant
   placement in the
   presence of
   permanent molars

!  Continued alveolar
   development and the
   resultant open bite                                                 From Sharma A and Vargervik K, 2006
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites
                       Timing for Implant Placement

 Lateral cephalograms, taken one year
 apart demonstrating no dento-alveolar
 change
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites


Surgical Issues
!   Volume    of bone at desired
         implant sites
!     Lack of keratinized attached
         tissues
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites




    Prosthodontic Issues
    !   Status   of existing permanent dentition – which teeth to retain, which to remove
    !     Implant positions and arrangement
    !     Vertical dimension of occlusion – How much interoccclusal space
    !     Occlusal plane
    !     Fixed vs removable
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites




The maxillary overlay removable partial denture. This prosthesis restores the vertical dimension of
occlusion, helps idealize the occlusal plane and replaces the missing dentition.
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites




Fixed was chosen in this patient. Why?                            Key design features
!   Central incisors presented with normal size and shape         !   No ridge laps
!   Development  of the maxilla was relatively normal
                                                                  !   Proxy bush access
!     Normal amount of interocclusal space                                                Courtesy T.L. Chang
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites




!   The bar in the anterior region was milled to a 3 degree taper
!   This custom substructure was designed to resolve implant angulation problems
                                                                                      Courtesy T.L. Chang
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites




!   At   UCLA we prefer retrievable restorations as opposed to cemented ones. Therefore
         the suprastructure was retained with lingual set screws
                                                                                      Courtesy T.L. Chang
Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites

!   Finished
           prosthesis
!   Note the
           pink
     porcelain




                                                                                        Courtesy T.L. Chang
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                  in undesirable positions
 Conventional prosthodontic
 options are undesirable

 Why?
 !   Resorption
 !   Loss of keratinized
        attached tissues
 !    Wear and tear on existing
        dentition
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                       in undesirable positions
Issues
  !     Timing of implant placement
  !     Effect of growth on implants
  !     Effect of implants on growth
  !     Long term success rate ?
  !     Compliance
  !     Risk vs reward
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions

 •  Growth
    – No dentoalveolar growth
    – Downward and forward growth of the
      mandible


                                                                 From Sharma A and Vargervik K, 2006
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                 in undesirable positions




        •  Implants placed anterior portion of the maxilla and mandible
        •  Fixed vs Removable
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions




   Delivery – Age 13                                             From Sharma A and Vargervik, 2006)
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions
           Age 13            Age 17
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions




      Age 20 with remake of the prosthesis following orthognathic surgery
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions




    Issues
        Provisionalization
                                                                        Courtesy Dr. R. Faulkner
        Fate of permanent dentition
Group III – Children who are completely edentulous in one arch or have
                one or two teeth in undesirable positions




Issues
!   Provisionalization
!   Fate   of permanent dentition                            Courtesy Dr. R. Faulkner
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions




         Completed restorations
                                                                        Courtesy Dr. R. Faulkner
Group III – Children who are completely edentulous in one arch or have one or two teeth
                                in undesirable positions


    •  Implants can be placed at an early age dependent upon
       compliance
    •  Surgery may be necessary when growth is complete to correct
       the anticipated jaw discrepancy
UCSF Study (Sharma A and Vargervik K, 2006)
                      Study Population
                                Average Age
Implant Placement               10.8 (5 to 14) yrs
Implant Restoration             12.3 (6 to 15) yrs.
UCSF Study (Sharma A and Vargervik K, 2006)
         Followup – October 2005

   Time since placed     139 (125 - 170) months
   Time since restored   130 (117 – 162) months
UCSF Study (Sharma A and Vargervik K, 2006)
          Mandible                        Maxilla
!   24   implants placed        !   22   implants placed
!     24 implants restored      !   21   implants restored (1 failed at 2nd stage)
!     100% integration          !   20   implants in function (Oct 2005) 1lost in
                                         1998
!     6 removable and 1 fixed
                                !     6 removable prosthesis
      prosthesis
Maxillary Implants              Mandibular Implants
             (6 patients)                     (7 patients)
!   Sinus lift              2 pts   Alveoplasty           7 pts
!   Bone graft (iliac)      3 pts   Bone grafts (iliac)   3 pts
!   Implants placed         22      Implants placed       24
Complications
!   Poor oral hygiene         4
!   Soft tissue hypertrophy   3
!   Difficulty adapting       2
Prosthetic Revision – 5 patients
!  1  maxillary overdenture
!   2 maxillary RPD’s
!   3 mandibular overdentures
!   1 mandibular fixed
UCSF Study (Sharma A and Vargervik K, 2006)
                      Summary
!   Implants can be placed in patients with ED
!   Implants can be successfully restored and loaded in patients with ED
!   Growth does not alter implant position (ankylosed)
!   Implants do not interfere with the growth
Implants for the Growing Child
!   Edentulous growing
     patient – Consider
     placing early
!   Partially
           dentate
     growing patient-
     approach with
     caution
Selected References
•  Hickey A, Vego T: Prosthetic treatments for patients with ectodermal dysplasia. J Prosthet Dent
   86:364-8, 2001
•  Guckes A, Scurria M, King T, et al: Prospective clinical trial of dental implants in persons with
   ectodermal dysplasia J Prosthet Dent 88:21-25, 2002
•  Sharma A and Vargervik K: Using implants for the growing child. J Calif Dent Assoc 34:71
   9-724, 2006
•  Odman J, Grodhal K et al: The effect of osseointegrated implants on dentoalveolar development: A
   clinical and radiographic study in growing pigs Eur J Orthod 13:279-286, 1991
Selected References

•  Thilander B, Odman J, et al: Aspects of osseointegrated implants inserted in growing jaws: A
   biometric and radiographic study in the young pig. Eur J Orthod 14:99-109, 1992
•  Kearns G, Perrott D, Sharma A: Placement of endosseous implants in grafted alveolar clefts.
   Cleft Palate Craniofac J 34:520-5, 1997
•  Kearns G, Sharma A, et al: Placement of implants in children and adolescents with heredity
   ectodermal dysplasia. Oral Surg Oral Med Oral Path Oral Radiol Endod 88:5-10, 1999

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Implants in Growing Children

  • 1. 13. Implants in Young Children and Adolescents Arun Sharma DDS Department of Preventive and Restorative Dentistry UCSF School of Dentistry John Beumer III DDS, MS Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry UCLA School of Dentistry This program of instruction is protected by copyright ©. No portion of this program of instruction may be reproduced, recorded or transferred by any means electronic, digital, photographic, mechanical etc., or by any information storage or retrieval system, without prior permission.
  • 2. Objectives !  Present some guidelines for implant therapy in children
  • 3. Issues !  Should Implants should be placed in children? !  If so, which patients? !  At what age should implants be placed?
  • 4. Implants in Young Children and Adolescents Our Primary Concern with Implant Placement is Growth !   The newborn lacks pronounced alveolar ridges !   Maxillary vertical development comes with developing tooth buds and the formation and eruption of teeth !   The maxilla comes down and forward secondary to sutural apposition and with downward and forward growth of the alveolar process associated with the eruption of primary and permanent teeth !   Growth of the mandible is not dependent on the presence of teeth
  • 5. Implants in Young Children and Adolescents Growth !   Inthe absence of maxillary teeth the alveolar ridges do not develop and the maxilla will be underdeveloped sagitally and vertically ! Mandibular growth is not dependent on the presence of teeth ! Therefore, in the presence of anadontia or hypodontia the relationship between the maxilla and mandible is disproportionate with most patients developing Class III relationships
  • 6. Implants in Young Children and Adolescents Growth !  Implants do not change position with growth and do not move vertically with alveolar development (Odman et al, 1991, Sharma and Vargervik , 2006) ! Implants placed in the anterior portions of the maxilla and mandible do not affect transverse growth of these structures (Thilander et al, 1992)
  • 7. Partial or Complete Anadontia Patient Classification (Sharma and Vargervik, 2006) !   Group I – Children congenitally missing one tooth with adjacent permanent teeth !   Group II – Children missing multiple teeth but with permanent teeth adjacent to edentulous sites !   Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions
  • 8. Group I – Children congenitally missing one tooth with adjacent permanent teeth Cleft lip and palate patients with single tooth defects secondary to partial anadontia Cleft Partial Anadontia Partial Anadontia
  • 9. Group I – Children congenitally missing one tooth with adjacent permanent teeth Dentition in Cleft Patients !   Missing Lateral Incisors – 40% !   Supernumerary Lateral Incisors– 7% !   Hypodontia – 50%
  • 10. Group I – Children congenitally missing one tooth with adjacent permanent teeth Management of the Missing Lateral Incisor in Clefts Implants - Issues ! Growth - Skeletal Development !   Dental alveolar !   Mandible and maxilla ! It is advisable to wait until two consecutive cephalometric films one year apart show no evidence of growth ! Site development !   Horizontal and vertical deficiencies usually present Courtesy A Sharma
  • 11. Group I – Children congenitally missing one tooth with adjacent permanent teeth Note: Gingival contours are not quite normal Why? Scarring Courtesy A Sharma associated with the closure and grafting the cleft Consequences: None. Almost all cleft patients have a low smile line.
  • 12. Group I – Children congenitally missing one tooth with adjacent permanent teeth Management of the Missing Lateral Incisor in Clefts Implants - Issues !   Consequences of early placement !  Implant will be submerged relative to the adjacent teeth with the attendant esthetic consequences !   Less favorable implant biomechanics ie. crown root ratios Courtesy A Sharma
  • 13. Note gingival contours. These are to be expected given the scarring secondary to the multiple surgical procedures necessary to close and graft the cleft. UCSF Data (Sharma and Vargervik, 2006) Courtesy A Sharma !   24 patients (15 male, 9 female) !  33 implants placed !   9 bilateral clefts !   31 implants restored !   15 unilateral clefts !   28 still in function
  • 14. Grafting the Cleft and Placing the Implants Average age in years !   Alveolar cleft bone graft - 14.3 !  Range (12 – 26) Median 15 !   Implant Placement - 18.1 !  Range (14 – 28) Median 19
  • 15. Group I – Children congenitally missing one tooth with adjacent permanent teeth Most clefts present with either horizontal or vertical bone deficiencies and require grafting prior to implant placement Implant Placement n = 33 !   Adequate bone 15 (45.4%) !   Need for regraft 18 (54.6%)
  • 16. Results !  Implants placed - 33 *2 implants failed at 2nd stage !  Implants restored - 31 *2 failed in a bilateral cleft after 4 years !  Implants in function - 28 *1 failed in a unilateral cleft after 11 years
  • 17. Follow up Time (months) !   Time since placement - 133.6 mths (Range 85 – 166. Median 130) !   Time since restored - 129 mths (Range 74 – 158, Median 121)
  • 18. Summary 2006 Data (Sharma and Vagervik, 2006) !  Dental Implants can be !  Dental implants placed in grafted successfully placed in alveolar clefts can be successfully grafted alveolar clefts – restored and loaded – 90.3% 93.9 % !   2 implants lost in one patient after 4 yrs ! 1 implant lost after 11 years
  • 19. UCSF Protocol (Sharma and Vargervik, 2006) !  Expand maxilla orthodontically (7 – 8 years) !  Close oro-nasal defect by grafting alveolar cleft (9 – 12 years) !  Guide cuspid into arch and maintain space for lateral !  If inadequate bone then regraft ! Place implant to replace lateral incisor (after growth is completed 15 – 19 years)
  • 20. Implants for those congenitally missing one tooth with adjacent permanent teeth secondary to partial anadontia Issues Orthodontics !  Diastemas closed !   Occlusion !  Anterior guidance !  7 mm between the root surfaces of the adjacent teeth Site enhancement !   Horizontal and vertical deficiencies
  • 21. Implants for those congenitally missing one tooth with adjacent permanent teeth secondary to partial anadontia •  Consolidate the arch segments before implant placement 14 y/o 19 y/o
  • 22. Timing for Implant Placement Lateral cephalograms, taken one year apart demonstrating no dento-alveolar change
  • 23. Implants for the patient with missing lateral incisors Distance between roots !  7 mm Avoid small diameter implants
  • 24. Implants for the patient with missing lateral incisors
  • 25. Implants for the patient with missing lateral incisors Issues •  Avoid small diameter implants •  Implant position and angulation •  Surgical templates •  Gingival contours •  Anterior guidance •  Screw retention
  • 26. Implant position Surgical Placement •  Screw access channel should exit through the cingulum (arrow) •  Head of the implant should be 2-4 mm below the proposed CEJ 2-4 mm
  • 27. This implant has been placed to Implant positioning far beneath the gingiva. Result: The depth of the peri-implant is excessive leading to an increased risk of Attachment peri-implantitis and level progressive bone loss around the Gingival implant. margin 30 months later Avoid labial inclinations
  • 28. Implant positioning Custom abutments - Labially inclined implants
  • 29. Implants for the patient with missing lateral incisors
  • 30. Implants for the patient with missing lateral incisors Brother – implant placed at age 18 yrs 6 mths Sister – implant placed at age 16 yrs 2 mths
  • 31. Implants in Patients with Ectodermal Dysplasia and Nonsyndromic Forms of Partial Anadontia Group II – Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions
  • 32. Heriditary Ectodermal Dysplasia !  Inherited: 1 in 100,000 live births !  Many variants !  Ectodermal tissues affected ! Hair ! Nails ! Teeth ! Sweat Glands
  • 33. Ectodermal Dysplasia Dental Problems !   Unpredictable tooth eruption and loss !   Poorly shaped crowns and roots !   Defective enamel formation !   Lack of alveolar development with closed vertical dimension of occlusion !   Class III jaw relation !   Prosthodontic challenges !   Group II vs Group III
  • 34. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites –
  • 35. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Implants - Advantages !   Improved stability, retention and support !   Improved mastication efficiency !   Preservation of residual tissues !  Remaining teeth !  Bone
  • 36. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Issues – Orthodontic care • Consolidate permanent dentition and the edentulous spaces
  • 37. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Issues !   Growth and timing of implant placement !   Prefer to wait until growth is completed !   Implants can be considered prior to completion of growth but the patient and family must recognize that the restoration is provisional
  • 38. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Issues – Retention of residual permanent dentition •  Permanent and deciduous dentition are often used to support provisional restorations •  Permanent dentition may be sacrificed at a later date in order to idealize the position and arrangement of implants
  • 39. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Issues – Interocclusal space •  Even when patients retain some permanent dentition there may be excessive interocclusal space •  The vertical dimension of occlusion must be restored if facial height and an a favorable esthetic result obtained
  • 40. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Issues !   Orthognathic surgery !   Occlusal plane !   Fixed vs removable !  Lack of maxillary development favors removable in the maxilla !   In the mandible fixed is generally favored
  • 41. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites !  Early implant placement in the presence of permanent molars !  Continued alveolar development and the resultant open bite From Sharma A and Vargervik K, 2006
  • 42. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Timing for Implant Placement Lateral cephalograms, taken one year apart demonstrating no dento-alveolar change
  • 43. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Surgical Issues !   Volume of bone at desired implant sites !   Lack of keratinized attached tissues
  • 44. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Prosthodontic Issues !   Status of existing permanent dentition – which teeth to retain, which to remove !   Implant positions and arrangement !   Vertical dimension of occlusion – How much interoccclusal space !   Occlusal plane !   Fixed vs removable
  • 45. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites The maxillary overlay removable partial denture. This prosthesis restores the vertical dimension of occlusion, helps idealize the occlusal plane and replaces the missing dentition.
  • 46. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites Fixed was chosen in this patient. Why? Key design features !   Central incisors presented with normal size and shape !  No ridge laps !   Development of the maxilla was relatively normal !   Proxy bush access !   Normal amount of interocclusal space Courtesy T.L. Chang
  • 47. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites !   The bar in the anterior region was milled to a 3 degree taper !   This custom substructure was designed to resolve implant angulation problems Courtesy T.L. Chang
  • 48. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites !   At UCLA we prefer retrievable restorations as opposed to cemented ones. Therefore the suprastructure was retained with lingual set screws Courtesy T.L. Chang
  • 49. Group II - Children missing multiple teeth but with permanent teeth adjacent to edentulous sites !   Finished prosthesis !   Note the pink porcelain Courtesy T.L. Chang
  • 50. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions
  • 51. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Conventional prosthodontic options are undesirable Why? !   Resorption !   Loss of keratinized attached tissues !  Wear and tear on existing dentition
  • 52. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Issues !   Timing of implant placement !   Effect of growth on implants !   Effect of implants on growth !   Long term success rate ? !   Compliance !   Risk vs reward
  • 53. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions •  Growth – No dentoalveolar growth – Downward and forward growth of the mandible From Sharma A and Vargervik K, 2006
  • 54. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions •  Implants placed anterior portion of the maxilla and mandible •  Fixed vs Removable
  • 55. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Delivery – Age 13 From Sharma A and Vargervik, 2006)
  • 56. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Age 13 Age 17
  • 57. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Age 20 with remake of the prosthesis following orthognathic surgery
  • 58. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Issues Provisionalization Courtesy Dr. R. Faulkner Fate of permanent dentition
  • 59. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Issues !   Provisionalization !   Fate of permanent dentition Courtesy Dr. R. Faulkner
  • 60. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions Completed restorations Courtesy Dr. R. Faulkner
  • 61. Group III – Children who are completely edentulous in one arch or have one or two teeth in undesirable positions •  Implants can be placed at an early age dependent upon compliance •  Surgery may be necessary when growth is complete to correct the anticipated jaw discrepancy
  • 62. UCSF Study (Sharma A and Vargervik K, 2006) Study Population Average Age Implant Placement 10.8 (5 to 14) yrs Implant Restoration 12.3 (6 to 15) yrs.
  • 63. UCSF Study (Sharma A and Vargervik K, 2006) Followup – October 2005 Time since placed 139 (125 - 170) months Time since restored 130 (117 – 162) months
  • 64. UCSF Study (Sharma A and Vargervik K, 2006) Mandible Maxilla !   24 implants placed !   22 implants placed !   24 implants restored !   21 implants restored (1 failed at 2nd stage) !   100% integration !   20 implants in function (Oct 2005) 1lost in 1998 ! 6 removable and 1 fixed !   6 removable prosthesis prosthesis
  • 65. Maxillary Implants Mandibular Implants (6 patients) (7 patients) !   Sinus lift 2 pts Alveoplasty 7 pts !   Bone graft (iliac) 3 pts Bone grafts (iliac) 3 pts !   Implants placed 22 Implants placed 24
  • 66. Complications !  Poor oral hygiene 4 !   Soft tissue hypertrophy 3 !   Difficulty adapting 2
  • 67. Prosthetic Revision – 5 patients !  1 maxillary overdenture !   2 maxillary RPD’s !   3 mandibular overdentures !   1 mandibular fixed
  • 68. UCSF Study (Sharma A and Vargervik K, 2006) Summary !  Implants can be placed in patients with ED !   Implants can be successfully restored and loaded in patients with ED !   Growth does not alter implant position (ankylosed) !   Implants do not interfere with the growth
  • 69. Implants for the Growing Child !   Edentulous growing patient – Consider placing early !   Partially dentate growing patient- approach with caution
  • 70. Selected References •  Hickey A, Vego T: Prosthetic treatments for patients with ectodermal dysplasia. J Prosthet Dent 86:364-8, 2001 •  Guckes A, Scurria M, King T, et al: Prospective clinical trial of dental implants in persons with ectodermal dysplasia J Prosthet Dent 88:21-25, 2002 •  Sharma A and Vargervik K: Using implants for the growing child. J Calif Dent Assoc 34:71 9-724, 2006 •  Odman J, Grodhal K et al: The effect of osseointegrated implants on dentoalveolar development: A clinical and radiographic study in growing pigs Eur J Orthod 13:279-286, 1991
  • 71. Selected References •  Thilander B, Odman J, et al: Aspects of osseointegrated implants inserted in growing jaws: A biometric and radiographic study in the young pig. Eur J Orthod 14:99-109, 1992 •  Kearns G, Perrott D, Sharma A: Placement of endosseous implants in grafted alveolar clefts. Cleft Palate Craniofac J 34:520-5, 1997 •  Kearns G, Sharma A, et al: Placement of implants in children and adolescents with heredity ectodermal dysplasia. Oral Surg Oral Med Oral Path Oral Radiol Endod 88:5-10, 1999