This document provides guidance on writing the materials and methods section of a research study. It discusses including a list of all materials used, such as live organisms, reagents, chemicals, and experimental units. The materials and methods section should specify these materials in sufficient detail and describe the procedures to allow others to evaluate and replicate the study. It is important to control for experimental error by using proper research design, replication, and statistical analysis to reduce or eliminate errors from instruments, limited samples or trials, and lack of controls. The materials and methods section should be written in an expository style using future tense for proposed studies and past tense for technical reports, without personal pronouns, spelling out numbers if they start sentences, and including diagrams to