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EPIDEMIOLOGY
OF MUMPS
DR. MAHESWARI JAIKUMAR.
maheswarijaikumar2103@gmail.com
MUMPS
• An acute infectious disease
caused by a RNA virus classified
as genus Rubulavirus of the
family paramyxoviridae.
• This organism has a predilection
for glandular and nervous tissue.
• Clinically the disease is
recognized by non-suppurative
enlargement and tenderness of
one or both the parotid glands.
• Other organs may be involved.
• Constitutional symptoms vary, or
may be in apparent.
• The disease occurs throughout
the world.
DISEASE BURDEN
• In most part of the world, the
annual incidence of mumps in
the absence of immunization is
in the range of 100-1000
cases/100,00 population with
epidemic peak every 2-5 years.
• Natural infection confers a life
long immunity.
AGENT FACTORS
AGENT
• The causative agent, Myxovirus
parotiditis is a RNA virus of the
myxovirus family.
• The virus can be grown readily in
chick embryo or tissue culture.
There is only one serotype.
SOURCE OF INFECTION
• Both clinical and subclinical
cases.
• The virus can be isolated from
saliva or from swabs taken from
the surface of Stenson’s duct.
• Virus has also been found in the
blood, urine, human milk and
cerebro spinal fluid (in one case)
COMMUNICABILITY
• Usually 4-6 days before and at
the onset of parotitis.
• Once the swelling has subsided,
the case may be regarded as no
longer infectious.
SECONDARY ATTACK
• Estimated to be about 86 %
HOST FACTORS
• AGE AND GENDER : Mumps is
frequently seen among children of the
age group 5-9 yrs.
• However no age is exempt if there is no
previous immunity. The disease tends
to be more severe in adults than in
children.
IMMUNITY
• One attack, clinical or subclinical
infection confers a life long
immunity.
• Most infants below the age of 6
months are immune because of
maternal antibodies.
ENVIRONMENTAL FACTORS
• Mumps is largely an endemic
disease.
• Cases are reported throughout the
year, the peak incidence is in
winter and spring.
• Epidemics are associated with over
crowding.
MODE OF TRANSMISSION
• The disease is spread mainly by
droplet infection and after direct
contact with an infected person.
INCUBATION PERIOD
• Varies from 2 to 3 weeks,
usually 18 days.
CLINICAL FEATURES
• Mumps is a generalized virus
infection.
• In 30 to 40 % cases infection is
clinically non apparent.
• In clinically apparent cases, it is
characterized by pain and
swelling either in one or both
the parotid glands but also may
involve sublingual and
submandibular glands.
PAROTID GLAND
• The case (child) complains of
“ear ache "on the affected side
prior to the onset of swelling.
• This is accompanied by pain and
stiffness on opening the mouth
before the swelling of the gland
is evident.
• Mumps may also affect the
testes, pancreas, CNS, ovaries,
prostate gland.
• In severe cases there may be
fever, headache and other
constitutional symptoms which
may last from 3-5 days.
• The swelling subsides slowly
over 1-2 weeks.
COMPLICATIONS
• Complications are not serious.
• They are orchitis, ovaritis,
pancreatitis, meningo-
encephalitis, thyroiditis, neuritis,
hepatitis and myocarditis.
PREVENTION
• Highly effective live attenuated
vaccine is now available.
• The commonly vaccine is the JERYL-
LYNN, RIT 4385, LENINGRAD-3, L-
ZAGARB and URABE strains.
• A single dose of
(0.5ml)intramuscularly produces
detectable antibodies in 95% of
vaccinees.
• MMR vaccine is administered as
a trivalent vaccine for children
(on completing 9 month)
HOME MANAGEMENT
CONTROL
• The control of mumps is difficult
because the disease is infectious
before a diagnosis can be made.
• However cases should be isolated
till the manifestations subside.
• Measures should be taken to
disinfect the articles used by the
patient.
• Contacts should be kept under
surveillance.
THANK YOU

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EPIDEMIOLOGY OF MUMPS

  • 1.
  • 2. EPIDEMIOLOGY OF MUMPS DR. MAHESWARI JAIKUMAR. maheswarijaikumar2103@gmail.com
  • 3.
  • 4.
  • 5. MUMPS • An acute infectious disease caused by a RNA virus classified as genus Rubulavirus of the family paramyxoviridae. • This organism has a predilection for glandular and nervous tissue.
  • 6. • Clinically the disease is recognized by non-suppurative enlargement and tenderness of one or both the parotid glands. • Other organs may be involved.
  • 7.
  • 8. • Constitutional symptoms vary, or may be in apparent. • The disease occurs throughout the world.
  • 9. DISEASE BURDEN • In most part of the world, the annual incidence of mumps in the absence of immunization is in the range of 100-1000 cases/100,00 population with epidemic peak every 2-5 years.
  • 10. • Natural infection confers a life long immunity.
  • 12. AGENT • The causative agent, Myxovirus parotiditis is a RNA virus of the myxovirus family. • The virus can be grown readily in chick embryo or tissue culture. There is only one serotype.
  • 13. SOURCE OF INFECTION • Both clinical and subclinical cases. • The virus can be isolated from saliva or from swabs taken from the surface of Stenson’s duct.
  • 14. • Virus has also been found in the blood, urine, human milk and cerebro spinal fluid (in one case)
  • 15. COMMUNICABILITY • Usually 4-6 days before and at the onset of parotitis. • Once the swelling has subsided, the case may be regarded as no longer infectious.
  • 16. SECONDARY ATTACK • Estimated to be about 86 %
  • 17. HOST FACTORS • AGE AND GENDER : Mumps is frequently seen among children of the age group 5-9 yrs. • However no age is exempt if there is no previous immunity. The disease tends to be more severe in adults than in children.
  • 18. IMMUNITY • One attack, clinical or subclinical infection confers a life long immunity. • Most infants below the age of 6 months are immune because of maternal antibodies.
  • 19. ENVIRONMENTAL FACTORS • Mumps is largely an endemic disease. • Cases are reported throughout the year, the peak incidence is in winter and spring. • Epidemics are associated with over crowding.
  • 20. MODE OF TRANSMISSION • The disease is spread mainly by droplet infection and after direct contact with an infected person.
  • 21. INCUBATION PERIOD • Varies from 2 to 3 weeks, usually 18 days.
  • 22. CLINICAL FEATURES • Mumps is a generalized virus infection. • In 30 to 40 % cases infection is clinically non apparent.
  • 23. • In clinically apparent cases, it is characterized by pain and swelling either in one or both the parotid glands but also may involve sublingual and submandibular glands.
  • 25. • The case (child) complains of “ear ache "on the affected side prior to the onset of swelling. • This is accompanied by pain and stiffness on opening the mouth before the swelling of the gland is evident.
  • 26. • Mumps may also affect the testes, pancreas, CNS, ovaries, prostate gland. • In severe cases there may be fever, headache and other constitutional symptoms which may last from 3-5 days.
  • 27.
  • 28. • The swelling subsides slowly over 1-2 weeks.
  • 29. COMPLICATIONS • Complications are not serious. • They are orchitis, ovaritis, pancreatitis, meningo- encephalitis, thyroiditis, neuritis, hepatitis and myocarditis.
  • 30.
  • 31. PREVENTION • Highly effective live attenuated vaccine is now available. • The commonly vaccine is the JERYL- LYNN, RIT 4385, LENINGRAD-3, L- ZAGARB and URABE strains.
  • 32.
  • 33. • A single dose of (0.5ml)intramuscularly produces detectable antibodies in 95% of vaccinees. • MMR vaccine is administered as a trivalent vaccine for children (on completing 9 month)
  • 34.
  • 35.
  • 37. CONTROL • The control of mumps is difficult because the disease is infectious before a diagnosis can be made. • However cases should be isolated till the manifestations subside.
  • 38.
  • 39. • Measures should be taken to disinfect the articles used by the patient. • Contacts should be kept under surveillance.