Microbivores in simple terms means microbiological pathogens destroyer It is an ideal nanotechnology-based drug delivery system which is—self- powered, computer-controlled medical nanorobot system capable of digitally precise transport, timing, and targeted delivery of pharmaceutical agents to specific cellular and intracellular destinations within the human body

1. MICROBIVORES
GUIDED BY:
PARVATHY S B
ASSISTANT PROFESSOR
DEPARTMENT OF ECE
ACE COLLEGE OF ENGINEERING
PRESENTED BY:
AMAL B R
ROLL NO -14441003
S7-ECE

2. OUTLINE
AIM
 INTRODUCTION
VARIOUS CONDITIONS IN BODY
PRIMARY PHAGOCYTIC SYSTEMS
APPLICATIONS
 ADVANTAGES
DISADVANTAGES
CONCLUSION
REFERENCES
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3. AIM
To know about the ideal nanotechnology-based
drug delivery system and its various features.
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4. INTRODUCTION
Microbivores in simple terms means microbiological pathogens destroyer.
 It is an ideal nanotechnology-based drug delivery system which is—self- powered, computer-controlled medical
nanorobot system capable of digitally precise transport, timing, and targeted delivery of pharmaceutical agents to
specific cellular and intracellular destinations within the human body.

5. VARIOUS CONDITIONS
IN BODY
 SEPSIS
 SEPTICEMIA
 BACTEREMIA
 PHAGE THERAPY
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6. MICROBIVORE
Artificial white blood cell or nanorobotic phagocytes.
Spheroid device 3.4 µm in diameter.
Consist of 610 billion precisely arranged atoms.
Traps blood pathogens & breaks them.
1000 times faster than white blood cells.
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7. PRIMARY PHAGOCYTIC
SYSTEMS
Reversible microbial binding sites
Telescoping grapples
Morcellation chamber
Digestion chamber
Ejection piston and exhaust port
Power supply and fuel buffer tankage
Sensors
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8. REVERSIBLE
MICROBIAL BINDING
SITES
Acquire a pathogen to be digested.
 A collision between a bacterium and the
nanorobotic device allows to recognize reversible
binding sites.
 Bacteria employ right-handed amino acids in
their cellular coats.
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9. TELESCOPING
GRAPPLES
Telescoping robotic grapples establish secure
anchorage to the microbe's plasma membrane.
Grapple force sensors inform the onboard
computer of the captive microbe's footprint size
and orientation.
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10. MORCELLATION
CHAMBER & DIGESTION
CHAMBER
The bacterium is internalized into the
morcellation chamber.
Bacterium is minced into nanoscale pieces.
Remains are pistoned into the digestion
chamber which consists of a pre-programmed set
of digestive enzymes.
These enzymes are injected and extracted 6
times during a single digestion cycle.
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11. EJECTION PISTON AND
EXHAUST PORT
Egestion is an annular-shaped ejection piston
comprised of a 20-nm thick piston pusher plate
driven by at least two 2-micron long.
Afterwards, the piston is retracted, effectively
pulling a vacuum in the DC in preparation to
receive the next batch of morcellate from the MC.
Exhaust port door must be opened prior to
activation of the ejection piston to allow the
digesta to escape.
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12. SENSORS
The microbivore needs a variety of external
and internal sensors to complete its tasks.
 External sensors include chemical sensors for
glucose, oxygen, carbon dioxide.
Acoustic communication sensors mounted
within the nanorobot hull permit the microbivore
to receive external instructions from the
attending physician.
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13. Want big impact?
Use big image.
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14. APPLICATIONS
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Drug delivery
Body surveillance
Surgery
Cancer detection and treatment
Gene therapy
 Diabetes treatment

15. ADVANTAGES
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Most animal cells are 10,000 to 20,000 nm in diameter so microbivores are easy to inject.
 Glucose or natural body sugars and oxygen might be a source for propulsion.
1000 times faster & 80 times more efficient than natural phagocytes.
Completely destroy one pathogen in just 30 seconds.

16. DISADVANTAGES
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Change in behaviour at nano level,may not be suitable for body.
High cost
Larger nanoparticles may accumulate in vital organs.
Nanorobots of larger size will block capillary flow.

17. The concept of microbivores is just a
theoretical justification till now.
But the recent advancement in the field of
nanotechnology gives the hope of the
effective use of this technology in medical
field.
Diseases like AIDs , cancer can be treated
permanently at any stage using these
technologies.
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CONCLUSION

18. REFERENCES
www.ijtra.com Special Issue 41 (AVALON) (March 2016), PP. 70-74
http://www.imm.org/publications/reports/rep025/
http://www.kurzweilai.net/meme/frame.html?main=/articles/art0453.html?
http://www.rfreitas.com/Nano/Microbivores.htm
Soft Machines: Nanotechnology and Life by Richard Anthony Lewis Jones
www.nanomedicine.org
www.nanorobots.com
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