What factors affect the degree of membrane fluidity? Explain in detail the Fluid Mosaic Model. Solution Degree of membrane fluidity is affected by many factors as follows: Fluid Mosaic model describes the bilayer structure of plasma membrane having various phospholipids, cholestrols, carbohydrate, and membrane proteins embedded into it. main composition of the plasma layer is Phospholipid Bilayer Hydrophobic ends of the lipid bilayer form the skeleton of the membrane whereas hydrophilic ends form hydrogen bonds with other molecules like water on both sides of the membrane. Middle part of membrane is hydrophobic in nature. Other than lipids, proteins and carbohydrate are other main constituents of the membrane. Proteins are folded and embedded into the membrane. Carbohydrates are found at the outer part of membrane and generally are found attached to proteins or lipids..