This document discusses wrinkles and treatments to avoid them. It begins by defining cosmetics and cosmeceuticals. It then classifies cosmeceuticals and discusses anti-aging and the types of wrinkles. There are four main types of wrinkles: atrophic crinkling rhytids caused by collagen and elasticity loss; permanent elastic creases from repeated facial expressions; dynamic expression lines from muscle movements; and gravitational folds from aging and gravity. Treatments discussed include prescription and herbal creams containing ingredients like retinol, hyaluronic acid, and antioxidants to exfoliate, hydrate, and rebuild collagen. Several herbal cosmeceutical formulations using ingredients like aloe vera

1. WRINKLES
BY: SHRESTHA
1ST M.PHARMA
AL AMEEN COLLEGE OF PHARMACY
DEPT. OF. PHARMACEUTICS

2. CONTENTS
 INTRODUCTION TO COSMETICS
 WHAT IS COSMECUTICALS
 CLASSIFICATION OF COSMECEUTICALS
 ANTI AGING
 WRINKLES
 TYPES OF WRINKLES
 TREATMENT TO AVOID WRINKLES
 HERBAL TREATMENT
 REFERENCES

3. INTRODUCTION….
About Cosmetics
• The word natural products is defined as existing in (or) caused by nature
,cultivated (or) uncultivated , not artificial , wild existing in natural state .
• The word COSMETICS arises from a greek word ‘KOSMETICOS’ which
means to adorn ( more attractive ).
• Cosmetics are used to enhance and alter the appearance of the face or
fragrance and texture of the body. Many cosmetics are designed for use
of applying to the face, hair, and body. They are generally mixtures of
chemical compounds; some being derived from natural sources, and
some being synthetics or artificial.

4. WHAT IS COSMECEUTICALS….. ?
•Cosmeceuticals are cosmetic products with biologically active
ingredients purporting to have medical or drug-like benefits.
• The term “cosmeceutical” was introduced by dermatologist Dr
Albert Kligman in 1984 and is derived from a combination of
the words cosmetic and pharmaceutical.
• Cosmeceuticals are products that have both cosmetic and
therapeutic (medical or drug-like) effects, and are intended to
have a beneficial effect on skin health and beauty. Like
cosmetics, they are applied topically as creams or lotions but
contain active ingredients that have an effect on skin cell
function.

5. • Cosmeceuticals are available “over-the-counter” (without
prescription) and are generally used as part of a regular skin
care regime to help improve skin tone and texture, pigmentation
and fine lines.
THE MARRIAGE OF COSMETICS TO PHARMACEUTICALS………..
Cosme + Ceutical

6. CLASSIFICATION OF COSMECEUTICALS….
• SKIN : Anti-Acne , Anti-Inflammatory , Antioxidant, Anti-
wrinkle, Anti-aging , Astringent , Depigmentation ,
Moisturizing, Bleaching , Cleansing, Antiseptic ,
Antiseptic Cooling effect , Sun Screen , Smoothening of
skin , Nourishing to skin ETC.
• HAIR : Anti dandruff , Anti- Lice ,Hair tonic ,Hair
wash, Hair dye , Hair conditioner , Shining of
hairs, Reduce hair loss etc.
• OTHERS : Toothpastes, Toothpowders

7. ANTI AGING

8. Anti aging
• The General aging process, which is genetically determined
and occurs by the passing of time, is called Intrinsic skin
aging or the chronological aging process, where as the
skin aging process induced by environmental factors is called
Extrinsic skin aging.
• Intrinsic aging occurs as a natural result of aging; it affects
the skin on the entire body, including the photoprotected
areas in a similar manner. Intrinsic aging can be considered
as a slow, continuous, and irreversible tissue degradation .
However, people of identical chronological age may appear to
have younger- or older-looking skin.

9. • The Intrinsically aged skin can be characterized primarily by
functional alterations, such as thinning of the dermis, degeneration
of the elastin network, and loss of hydration.
• Extrinsic aging can be defined as the acceleration of intrinsic aging
caused by exposure to various environmental factors, such as sun,
wind, smoking, and air pollutants . The primary factors causing
human skin aging are UV radiation from the sun as well as
smoking.
oIt has been known that smoking leads to
premature aging, i.e., smokers in general look
older than their chronological age. It is more
interesting, however, that smoking has been
shown to be a great contributor to facial wrinkling
than sun exposure
DID YOU
KNOW….??

11. WRINKLES
• Wrinkle are also known as a Rhytide, is a fold, ridge or
crease in the skin or on fabric. Skin wrinkles typically appear
as a result of aging processes such as Glycation, habitual
sleeping positions , loss of body mass, or temporarily, as the
result of prolonged immersion in water. Age wrinkling in the
skin is promoted by habitual facial expressions , aging, sun
damage, smoking , poor hydration, and various other factors.

12. Types of wrinkles……..
1. Atrophic Crinkling Rhytids :
• These wrinkles are those little parallel lines that disappear
when our skin is stretched taut.
• They can occur on our face, or anywhere on our body
 What Causes Them
• These lines are a result of a loss of collagen and elasticity
which leads to skin sagging.
• Sun damage UV exposure unleashes free radicals in our skin
that break down collagen and elastin, the building blocks that
give our skin firmness and structure.

13. 2. Permanent Elastic Creases
• These are crease lines that end up becoming permanent
wrinkles as we age . The little lines tend to show up on our
cheeks, upper lip, and the base of our necks.
• Smoking is also a big factor in deepening these creases, like
those lines you get around your lips from repeatedly pursing
your mouth.
3. Dynamic Expression Lines
• These fun lines are the ones which we get from repeated facial
muscle movements that cause creases in the skin that become
more permanent.

14. • They usually show up around the mouth, eyes, and forehead.
• What Causes Them - we get these lines from basically living our
life and being a human being . They’re like a collection of little
moments from every time we squinted on a sunny day, laughed at
an inside joke, or frowned when a character gets killed off on your
favourite show.
 Unless you want to become a robot and stop expressing yourself,
you’re gonna get these lines and creases on your face.
4. Gravitational Folds
• These are those wrinkles that occur
naturally with age as our skin loses
structure and starts tofold and sag.
What Causes Them As the name suggests,
time + gravity = gravitational folds.
We can chalk this one up to good ol ’ aging.As we get older, our
skin starts to lose collagen and elastin leading to wrinkling and
sagging.

15. Treatment to avoid wrinkles….???
• If we want to get some wrinkle-smoothing power out of your skincare, we
should look for the formulas that include these age-defying ingredients
which are…
• Retinol The vitamin A derivative, retinol, smooth's skin by gently exfoliating
to lift away dead skin cells and encourage new cell turnover.
• EG: tretinoin cream ,ROC Retinol correxion deep wrinkle cream
• Hyaluronic Acid Fine lines and wrinkles are made more apparent when
your skin is dry or dehydrated.
Hyaluronic acid is a mega moisture
humectant, which means it grabs moisture
and holds it to your skin’s surface to deliver
hydration

16. • Antioxidants are the superheroes that swoop to defeat that
sun damage can cause free radicals to break down collagen
and it helps to support skin healing by encouraging cell repair
and rebuilding collagen and elastin.
EG : L- ASCORBIC ACID CREAM 20%
• Peptides are chains of amino acids which make up the skin
protein, collagen . By applying peptides product we’re
rebuilding up the blocks of collagen to fortify skin and bring
back its firmness.

17. HERBAL TREATMENT
Pat Anjali Anti – Wrinkle face cream
INGRIDIENTS QUANTITY TAKEN
• Aloe Vera 1500 mg
• Wheat Germ 100mg
• Jojoba 30mg
• Cucumber 30mg
• Almond 25mg
• Sandalwood 5mg
• Turmeric 15mg
• Papaya 25mg
• Banana 25m mg
• other rich herbs q.s

18.  Himalaya anti- wrinkle cream
Ingredient's used
• Caprylic triglyceride
• Aloe barbadensis leaf juice
• Lens esculent a seed extract
• Glyceryl stearate
• Ricinus communis seed oil
• Cetyl alcohol
• Sucrose cocoate
• Citrus limon peel extract
• Sodium benzoate
• Carbomer
• Disodium EDTA

19.  Biotique bio Carrot seed anti -aging after bath body oil :
• Ingridients used Quaantity taken
• Carrot seed oil 0.5%
• Almond 1.0%
• Ground nut oil 2.0%,
• Mahuva oil 3.5%
• Rai oil 0.7%

20.  Forest essential external youth formula
Dates and litchi
• Dates (Phoenix dactylifera)
• Sweet almond oil (prunus amygdalus dulcis)
• Genhu (Triticum vulgare)
• Kasturi manjal (turmeric)
• Witch hazel
• Litchi
• Fenugreek
• Amla fruit extract

21.  L- ASCORBIC ACID CREAM 20% Ingredient used :
•
• L- ascorbic acid – increases collagen synthesis, powerful
antioxidant and rich source of vit C.
• Phenyl trimethicone – skin conditioning agent
• Dimethicone - moisturizer
• Cyclopentasiloxane – reduces fines lines and wrinkle
• Tocopheryl acetate - potent antioxidant and reduces
photo damage.

22.  Anti – wrinkle deep wrinkle night moisturizer
• Ingridient used
• Retinol
• Tocopherol
• Ppg2 (myristyl ether propionate)
• Cetearyl alcohol
• Cetyl dimethicone
• Hexyldecylstearate
• Bisabolon
• PEG100 stearate
• Methylparaben
• Disodium EDTA

23. PONDS AGE MIRACLE night cream review
• Water
• Dimethicone cross polymer
• Peg-10 dimethicone
• Glycerine
• Triehoxycaprylysilane
• Caprylic acid
• Camelina Sativum seed oil
 OLAY Age defining anti wrinkle cream
• Aqua
• Glycerine
• Isopropyl palmitate
• Disodium edta
• Palmatic acid
• Limonene
• citronellol

24. references
• COSMECEUTICALS by Y. Madhusudan Rao ,
Shayeda
• Poucher’ s perfume cosmetics and soaps, 10th
edition
• Harry’s cosmeticology 8th edition
• Introduction to cosmetic formulation and
technology, by Gabirella Baki, Kenneth s.
Alexander