This document discusses hair structure and the hair growth cycle. It notes that hair grows from follicles in the dermis and is composed mainly of keratin protein. Hair has several layers - the medulla, cortex, and cuticle. The hair growth cycle consists of the anagen (growth), catagen (regression), telogen (rest), and exogen (shedding) phases. During anagen, hair grows rapidly from the hair bulb. Catagen is a transition phase where growth stops. Telogen is a resting phase where the hair remains until it sheds during exogen. The document also briefly discusses formulations for different types of shampoos.

1. Hair and
Hair Growth Cycle
Siddu K M
M Pharm
Department of Pharmaceutics
Al Ameen College of Pharmacy, Bengaluru

2. What is hair?
• Hair is a protein filament that grows from follicles found in the
dermis, or skin.
• It is one of the defining characteristics of mammals.
• It is an important biomaterial primarily composed of protein, notably
keratin.

3. The main functions of Hair
• Thermo regulation
• Protection
• Facilitation for evaporation of perspiration
• Heat insulation on head

4. Structure of Hair

5. Anatomy of Hair

6. Layers of Hair
1. Medulla
2. Cortex
3. Cuticle

7. Medulla
oCentre layer of hair shaft
oNot always present , can be continuous broken
oMade up of large loosely connected cells
oNo known function

8. Cortex
oLargest and most important layer of the hairshaft
oDetermines the texture of the hair
oContains melanin and moisture

9. Cuticle
oThe outer layer of the hair shaft
oMade up of clear overlapping scales
oContains no melanin

10. Hair growth cycle
• Hair development is a continuous cyclic process and all mature
follicles go through a growth cycle consisting of growth (anagen),
regression (catagen), rest (telogen) and shedding (exogen) phases.
• The duration of the phases changes based on the location of the hair
and also personal nutritional and hormonal status and age.

12. Anagen
• The anagen is the active growth phase in which the
follicle enlarges and takes the original shape and the
hair fiber is produced.
• Almost 85–90% of all scalp hairs are in anagen.
• Mitosis is occurring
• Hair grows between 1 to 1.5 cm per month.
• Hair bulb is round and full & contains melanin in it.

13. Catagen
• At the end of anagen, mitotic activity of the matrix
cells is diminished and the follicle enters a highly
controlled involutionary phase known as catagen.
• Catagen lasts approximately 2 weeks in humans,
regardless of the site and follicle type.
• Transition stage
• Mitosis stops

14. Telogen
• The telogen stage is defined as the duration
between the completion of follicular regression and
the onset of the next anagen phase.
• Telogen stage lasts for 2–3 months.
• Approximately 10–15% of all hair is in telogen
stage.
• Hairs fall out , approx 50-80 hairs per day are lost.

15. SHAMPOOS AND HAIR RESTORING AGENTS
• A Shampoo is a preparation of a surfactant in a suitable form – liquid,
solid or powder which when used under the specialized conditions
will remove surface grease, dirt and skin debris from the hair shaft
and scalp without adversely affecting the user.
oIdeal properties
• It should produce good amount of foam.
• It should be easily removed on rinsing with water.
• It should impart a pleasant fragrance to the hair.
• It should not cause any side affects or irritation to the skin or eye.
• It should be effectively or completely remove dust or soil.
• It should not make the hand rough.

16. Formulation Of Different Types Of Shampoo
1. Powder Shampoo

17. 2. Lotion shampoo

18. 3. Liquid shampoo

19. 4. Anti dandruff shampoo

20. 5. Conditioning shampoo

21. 6. Herbal shampoo

22. 7. Mintop 10% Lotion

23. 8. Nizoral Shampoo 1%
Ketaconazole ………………..1%
Acrylic acid polymer
Butylated hydroxyl toluene
Cocamide MEA
FD & C BLUE #1
Fragrance
Glycol distearate
Polyquaternium -7
Quaternium -15
NaCl
Sodium cocayl sarcosinate
NaoH
SLS
Tetrasodium EDTA
Water

24. THANK YOU