Wilms' tumor is a rare, malignant kidney tumor that is most common in children under 5 years old. It makes up about 90% of all kidney tumors diagnosed in children. While the exact cause is unknown, risk factors include family history and certain birth defects. Symptoms can include an abdominal mass, swelling, pain, and high blood pressure. Diagnosis involves imaging tests, blood tests, biopsy and assessing the tumor stage. Treatment involves chemotherapy, surgery to remove the tumor and possibly the kidney, and sometimes radiation therapy. With treatment, about 90% of patients survive at least 5 years.
Wilms tumor (also called Wilms' tumor or nephroblastoma) is a type of childhood cancer that starts in the kidneys. It is the most common type of kidney cancer in children. About 9 of 10 kidney cancers in children are Wilms tumors.
Detailed Powerpoint Presentation on Wilms Tumour …. It includes definition with images, causes, sign and symptoms all treatment modalities with nursing responsibilities and recent research related to this...
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Wilms tumor (also called Wilms' tumor or nephroblastoma) is a type of childhood cancer that starts in the kidneys. It is the most common type of kidney cancer in children. About 9 of 10 kidney cancers in children are Wilms tumors.
Detailed Powerpoint Presentation on Wilms Tumour …. It includes definition with images, causes, sign and symptoms all treatment modalities with nursing responsibilities and recent research related to this...
oth Hodgkin's lymphoma and non-Hodgkin's lymphoma are lymphomas — a type of cancer that begins in a subset of white blood cells called lymphocytes. Lymphocytes are an integral part of your immune system, which protects you from germs.
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Please find the power point on Phototherapy in jaundice . I tried to present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
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2. INTRODUCTION
-A rare, malignant tumor of the kidney
-The most common intra-abdominal tumor in children
-Tumor is usually unilateral, favoring the left kidney, 5% of cases
affect both kidneys.
-Average age of diagnosis is 2 to 4 years old
-It is highly responsive to treatment with 90% of patients surviving
at least 5years
7. Risk Factors
Family history of Wilms’ tumor
African Americans have a higher incidence of WT (lower rate of disease in children of Asian
decent)
Increased rate of incidence in children with certain birth defects:
-Hypospadias
-Cryptorchidism
- Aniridia
- Hemihypertrophy
8. Signs andSymptoms
- Nontender, abdominal mass
- Abdominal swelling
- Abdominal pain
- Fever
- High blood pressure
- Vomiting
- Hematuria
- Loss of appetite
- Constipation
9. Diagnostic Testing
HISTORY
PHYSICAL EXAMINATION:- children with wilms tumor generally first present swollen
abdomen or with an obvious abdominal mass .
BLOOD ANALYSIS:-
-Hb%
-WBC
-PLATELET COUNT
-LFT
-RFT
10. Cont…..
-Abdominal ultrasound
-CT scan
-Intravenous Pyelography: Where dye injected into vein helps to show the structure of the
kidney
-Renal biopsy
-OTHER STUDIES CHEST –XRAY ,CT SCAN of the lungs,bone marrow biopsy may also be
done in order to see if the tumor has spread to other location.
12. 5 Stages
Stage 1: Cancer is found in one kidney only. Size is less than 7cm. Tumor can be completely
removed by surgery. 41% of all Wilms’ tumors are discovered in Stage 1
Stage 2: Cancer is found in one kidney only. Size is larger than 7cm. Tumor can be completely
removed by surgery. 23% of all Wilms’ tumors are discovered in Stage 2
Stage 3: Cancer is found in one kidney only. It has spread to nearby lymph nodes or other
structures of the abdomen and it cannot be completely removed by surgery. 21% of WT
discovered in Stage 3
Stage 4: Cancer is found in one kidney only. It has spread to distant parts of the body; most
commonly, the lungs, liver, bone and/or brain and it cannot be removed by surgery. 10% of WT
discovered in Stage 4
Stage 5: Cancer is found in both kidneys (bilaterally). 5% of WT discovered in Stage 5
14. chemotherapy
-Medication used to kill cancer cells.It is also called systemic
treatment. Because the drugs enters blood and kill cancer cell
throughout the body.
-Under chemotherapy drugs used for 6 months
-This treatment for tumors that have metastasized to
surrounding tissues
•Vincristine
•Doxorubicin
•Cyclophosphamide
•Carboplatin
15. Surgery
surgery to remove the tumor and perhaps the affected kidney in Stage 1 and Stage 2
Types
1. A partial nephrectomy: Is when the cancer and the part of the kidney are removed .It is
usually done if the other kidney is damaged
2. A simple nephrectomy: Is when the whole kidney is removed
3. A Radical nephrectomy: removes the entire kidney and tissue around it. Some time
some lymph nodes may also be removed
16. RADIATION
-In this radiation therapy Xray or other high energy rays are
used to kill cancer cells and shrink tumors
-It may be used before and after surgery and /or chemotherapy.
-Radiation therapy is not given in children below age of 1years.
17. NCLEX ALERT!
DON’T PALPATE THE ABDOMEN and prevent others from doing so. It may
disseminate cancer cells to other sites.
18. Nursing Care
Prior to Diagnostic Testing: Assess the child for allergies to dye or shellfish, Assist the child to remain
still, Instruct child to drink contrast medium if applicable, Sedate the child if prescribed
Prior to Surgical Resection: Do not palpate the abdomen, Provide emotional support, Provide
education to the child and family regarding treatment plan, ongoing therapy, and prognosis
Post Surgery: Administer prescribed analgesics, Monitor for signs of pain and infection, Monitor for
signs of hemorrhage, Monitor vital signs, Provide age-appropriate diversional activities, Keep child’s
skin clean and dry, Provide emotional support
Chemotherapy/Radiation: Medicate child with antiemetics prior to administration, Handle
chemotherapeutic agents carefully, Take care when radiation is in use (wear lead aprons), Observe
the mouth for mucosal ulcerations, Provide several food choices, allowing the child to choose
favorites, Offer cool fluids to prevent dehydration and soothe sore mucous membranes, Provide
education on side effects of chemotherapy/radiation, Use good hand hygiene, Instruct child to avoid
fresh fruits and vegetables, Avoid large crowds and sick visitors, Monitor for signs of bleeding, Avoid
invasive procedures and apply pressure to puncture sites for 5 mins.