The Wilcoxon signed-rank test is a non-parametric statistical test used to compare two related samples or repeated measurements on a single sample to assess if their population mean ranks differ. It can be used as an alternative to the paired t-test when the population cannot be assumed to be normally distributed. The test involves ranking the differences between paired observations, ignoring the signs of the differences, and comparing the sum of the ranks of the positive or negative differences to critical values to determine if there are statistically significant differences between the samples. A limitation is that observations with a difference of zero are discarded, which can be a concern if samples come from a discrete distribution.