This document provides an overview of major developments in Europe between 1450-1650, including the Reformation, Age of Exploration, and establishment of new empires. It summarizes key events like Martin Luther posting his 95 Theses in 1517, sparking the Protestant Reformation. It also outlines the spread of Calvinism and the establishment of the Church of England, as well as the Catholic Counter-Reformation and Council of Trent. The document then discusses the expansion of European powers like Spain, Portugal, and England through figures like Columbus, Da Gama and battles such as Lepanto.