Viruses
Chapter 2 Ce!s
  Section 3
What are viruses???
cold sores          the flu        measles        AIDS

virus
•nonliving particle
•strand of hereditary material surrounded by a protein
coating
•no nucleus or other organelles
•no cell membrane
•can have many shapes
•too small to be seen with the light microscope
how do viruses multiply
•all viruses can make copies of themselves
•they can’t do that without the help of a living cell
•the living cell is called a host cell
•crystallized viruses can be stored for years. Then, if
they enter an organism, they can multiply quickly.
•once a virus is in a host cell, the virus can act in 1 of 2
ways:
       •be active
       •become latent (inactive)
active viruses
When a virus enters a cell and is active, it causes the host cell to
make new viruses. This process destroys the host cell.


Steps that occur:
      virus aaches to a specific host cell
      virus’s hereditary material enters the host cell
      hereditary material causes the cell to make viral hereditary
      material and proteins
      new viruses form inside the host cell
      new viruses are released as host cell bursts open and is
      destroyed
latent viruses
virus enters the cell

its hereditary material can become part of the cell’s hereditary
material

does not immediately make new viruses or destroy the cell

as host cell reproduces, the viral DNA is copied

can be latent for years

certain conditions, whether inside or outside your body, cause
the latent virus to become an active virus
example:


 COLD SORE
 a latent virus in the body has become active
 cold sore is a sign that the virus is active and destroying
 cells in your lip
 when the cold sore goes away, the virus has become latent
 again
 virus is still in your body’s cells, but it is “hiding” and doing
 no apparent harm
how do viruses affect organisms?
Who can viruses aack?
     animals, plants, fungi, protists, bacteria
Some viruses only infect only specific kinds of cells...
     Some viruses are limited to one host species (ie: potato
     leafroll virus) or to one type of tissue.
     Some can affect a broad range of hosts. Rabies, for
     example, can infect humans and many animals.
The virus and the place it aaches to the surface on the host
cell must fit together exactly. Because of this, they usually
only aack one type of cell.
How do viruses move?
They cannot move by themselves. They reach a host’s
body by being carried by the wind or by being inhaled.
fighting
viruses
We fight viruses by geing VACCINES

they are used to prevent diseases

made form weakened virus particles that can’t cause
disease anymore

vaccines have been used to prevent many diseases, such as:
measles, mumps, smallpox, chicken pox, polio, rabies, swine
flu
first vaccine
   Edward Jenner is credited with developing the
 first vaccine in 1796.
  He developed a vaccine for smallpox, a disease
 that was still feared in the early twentieth
 century.
  Jenner noticed that people who got a disease
 called cowpox didn’t get smallpox.
  Jenner didn’t know he was fighting a virus
treating viral diseases
WHAT YOUR BODY DOES ON ITS OWN: make interferons.
What are interferons???
    proteins that are produced rapidly by virus-infected cells
    they move to non-infected cells, causing them to produce
    protective substances.
MEDICINE THAT CAN HELP: Antiviral drugs
Antiviral drugs can be given to infected patients to help fight a
virus.
Some are effective, but some have adverse side effects.
Antibiotics treat bacterial infections but not viral diseases
preventing viral diseases

Public health measures for preventing viral diseases
includes:

    Vaccinating people

    Improving sanitary conditions

    Quarantining patients

    Controlling animals that spread disease
research with viruses
Through research, scientists are discovering helpful uses for
some viruses.
Gene therapy substitutes normal hereditary material for
a cell’s defective hereditary material.
The normal material is enclosed in viruses that “infect”
targeted cells.
The new hereditary material replaces the defective hereditary
material.
Using gene therapy, scientists hope to help people with genetic
disorders and find a cure for cancer.
Viruses
Viruses

Viruses

  • 1.
  • 2.
    What are viruses??? coldsores the flu measles AIDS virus •nonliving particle •strand of hereditary material surrounded by a protein coating •no nucleus or other organelles •no cell membrane •can have many shapes •too small to be seen with the light microscope
  • 3.
    how do virusesmultiply •all viruses can make copies of themselves •they can’t do that without the help of a living cell •the living cell is called a host cell •crystallized viruses can be stored for years. Then, if they enter an organism, they can multiply quickly. •once a virus is in a host cell, the virus can act in 1 of 2 ways: •be active •become latent (inactive)
  • 4.
    active viruses When avirus enters a cell and is active, it causes the host cell to make new viruses. This process destroys the host cell. Steps that occur: virus aaches to a specific host cell virus’s hereditary material enters the host cell hereditary material causes the cell to make viral hereditary material and proteins new viruses form inside the host cell new viruses are released as host cell bursts open and is destroyed
  • 7.
    latent viruses virus entersthe cell its hereditary material can become part of the cell’s hereditary material does not immediately make new viruses or destroy the cell as host cell reproduces, the viral DNA is copied can be latent for years certain conditions, whether inside or outside your body, cause the latent virus to become an active virus
  • 9.
    example: COLD SORE a latent virus in the body has become active cold sore is a sign that the virus is active and destroying cells in your lip when the cold sore goes away, the virus has become latent again virus is still in your body’s cells, but it is “hiding” and doing no apparent harm
  • 10.
    how do virusesaffect organisms? Who can viruses aack? animals, plants, fungi, protists, bacteria Some viruses only infect only specific kinds of cells... Some viruses are limited to one host species (ie: potato leafroll virus) or to one type of tissue. Some can affect a broad range of hosts. Rabies, for example, can infect humans and many animals. The virus and the place it aaches to the surface on the host cell must fit together exactly. Because of this, they usually only aack one type of cell.
  • 12.
    How do virusesmove? They cannot move by themselves. They reach a host’s body by being carried by the wind or by being inhaled.
  • 13.
    fighting viruses We fight virusesby geing VACCINES they are used to prevent diseases made form weakened virus particles that can’t cause disease anymore vaccines have been used to prevent many diseases, such as: measles, mumps, smallpox, chicken pox, polio, rabies, swine flu
  • 14.
    first vaccine Edward Jenner is credited with developing the first vaccine in 1796. He developed a vaccine for smallpox, a disease that was still feared in the early twentieth century. Jenner noticed that people who got a disease called cowpox didn’t get smallpox. Jenner didn’t know he was fighting a virus
  • 16.
    treating viral diseases WHATYOUR BODY DOES ON ITS OWN: make interferons. What are interferons??? proteins that are produced rapidly by virus-infected cells they move to non-infected cells, causing them to produce protective substances. MEDICINE THAT CAN HELP: Antiviral drugs Antiviral drugs can be given to infected patients to help fight a virus. Some are effective, but some have adverse side effects. Antibiotics treat bacterial infections but not viral diseases
  • 18.
    preventing viral diseases Publichealth measures for preventing viral diseases includes: Vaccinating people Improving sanitary conditions Quarantining patients Controlling animals that spread disease
  • 19.
    research with viruses Throughresearch, scientists are discovering helpful uses for some viruses. Gene therapy substitutes normal hereditary material for a cell’s defective hereditary material. The normal material is enclosed in viruses that “infect” targeted cells. The new hereditary material replaces the defective hereditary material. Using gene therapy, scientists hope to help people with genetic disorders and find a cure for cancer.