This document discusses the physiological effects of positioning on ventilation and oxygen transport in patients. It notes that positioning restores ventilation to dependent lung regions more effectively than other methods. Positioning affects lung volumes, compliance, and arterial oxygenation by improving ventilation/perfusion matching in the lungs. Studies show that lung volume decreases from standing to sitting to supine positions, as abdominal contents push on the diaphragm. Position changes from supine to side lying can clear atelectasis from dependent lung regions. The document examines the effects of different positions on a patient's spirometry results, flows, volumes, and oxygen saturation as measured by devices like a spirometer and LifeShirt.