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Usage of Antibiotics in
Broiler Production
Sachith Sri Mihiraj
BSc (Special), M.Agri
 An antimicrobial drug used in the treatment and
prevention of bacterial infections
What is an Antibiotic?
 Treatment and prevention of bacterial infections
 Sub therapeutic doses
 Improve feed efficiency
 Growth stimulator
 Reduce economic losses to farmers
Why use Antibiotics?
 Bacitracin (e.g., BMD, Pennitracin MD, Albac)
 Chlortetracycline (e.g., Chloratet, Aureomycin)
 Lincomycin (e.g., Lincomx)
 Oxytetracycline (e.g., Terramycin)
 Penicillin
 Tylosin (e.g., Tylan)
 Virginiamycin (e.g., Stafac, V-Max)
 Ionophores
 Enrofloxacin
Common Antibiotics
Common Antibiotics Used in Sri
Lanka
 Product Name: Enrocip
 Active Ingredients:
Enrofloxacin 10%
 Indications: Salmonellosis,
pasteurellosis, mixed and
chronic infections.
 Category: Antibiotic,
administer as oral suspension
 Dosage – 10mg/kg
 Product Name: Dinatrim
 Active ingredients:
Micronized trimethoprim and
sulphadiazine
 Indications: Treatment for
salmonellosis, pathogenic e
coli, pasturella,
corynebacterium spp
 Category: Antibiotic come in
as oral suspension
 Product Name: Amoxycillin
50 %
 Active ingredients:
Amoxycillin Trihydrate
 Indications: Effective on E
coli, salmonella spp, and
corynebacterium spp
 Category: Antibiotic , come
in powder form
 Product Name: Bio Neoxyl
 Active ingredients:
Neomysin and
oxytetracycline
 Indications: Antibiotic
effective against E coli,
Salmonella and clostridium
spp Category: Antibiotic,
oral treatment
SULTRIM 48 %
Tylovet
TIAMULINE 10%
 Development of antibiotic resistant species of bacteria
Negative Effects
 Effects of drug residues in meat
 Drug hypersensitivity reaction
 Carcinogenic effect
 Mutagenic effect
 Teratogenic effect
 Disruption of Normal Intestinal Flora
 Reduce normal microbiota making the bird more
susceptible to pathogens
 Weaken the immune system, compromise liver function
and impair performance.
 Aminoglycosides and sulpphonamides can compromise
kidney function and impair mineral absorption
Negative effects contd.
 Only give antibiotics to animals under veterinary supervision.
 Not use antibiotics for growth promotion or to prevent
diseases in healthy animals.
 Vaccinate animals to reduce the need for antibiotics and use
alternatives to antibiotics when available.
 Promote and apply good practices at all steps of production
and processing of foods from animal and plant sources.
 Improve biosecurity on farms and prevent infections through
improved hygiene and animal welfare.
WHO Response
 Probiotics (Ex; Lactobacillus, Saccharomyces)
 Prebiotics (Ex; Biolex MB)
 Enzymes (Ex; Xylenes, amylase, protease combination)
 Organic acids (Ex; Citric acid, Formic acid)
 Bacteriocins (Ex; Albusin-B)
 Bacteriophages
 Phytogenic feed additives(Ex; Cinnamon, Fever tea, Garlic,
Black pepper)
 Essential oils (Ex; thymol, trans cinnamaldehyde, eugenol)
 Nanoparticles (Ex; Ag, Cu)
Alternatives
 Animal Diseases Act No. 59
 Ban of all antibiotics as growth promoters and in
medicated feed
 Stop issuing of license to import antibiotics (2019
onward)
 Completely stop usage of antibiotics in livestock by
2022
Government Regulation
 Mehdi. Y. (2018), “Use of antibiotics in broiler
production: Global impacts and alternatives”
 Beyene. T. (2015), “Veterinary Drug Residues in Food-
animal Products: Its Risk Factors and Potential Effects on
Public Health”
 http://www.who.int/news-room/fact-
sheets/detail/antibiotic-resistance
References

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Usage of Antibiotics in broiler production

  • 1. Usage of Antibiotics in Broiler Production Sachith Sri Mihiraj BSc (Special), M.Agri
  • 2.  An antimicrobial drug used in the treatment and prevention of bacterial infections What is an Antibiotic?
  • 3.  Treatment and prevention of bacterial infections  Sub therapeutic doses  Improve feed efficiency  Growth stimulator  Reduce economic losses to farmers Why use Antibiotics?
  • 4.  Bacitracin (e.g., BMD, Pennitracin MD, Albac)  Chlortetracycline (e.g., Chloratet, Aureomycin)  Lincomycin (e.g., Lincomx)  Oxytetracycline (e.g., Terramycin)  Penicillin  Tylosin (e.g., Tylan)  Virginiamycin (e.g., Stafac, V-Max)  Ionophores  Enrofloxacin Common Antibiotics
  • 5. Common Antibiotics Used in Sri Lanka  Product Name: Enrocip  Active Ingredients: Enrofloxacin 10%  Indications: Salmonellosis, pasteurellosis, mixed and chronic infections.  Category: Antibiotic, administer as oral suspension  Dosage – 10mg/kg
  • 6.  Product Name: Dinatrim  Active ingredients: Micronized trimethoprim and sulphadiazine  Indications: Treatment for salmonellosis, pathogenic e coli, pasturella, corynebacterium spp  Category: Antibiotic come in as oral suspension
  • 7.  Product Name: Amoxycillin 50 %  Active ingredients: Amoxycillin Trihydrate  Indications: Effective on E coli, salmonella spp, and corynebacterium spp  Category: Antibiotic , come in powder form
  • 8.  Product Name: Bio Neoxyl  Active ingredients: Neomysin and oxytetracycline  Indications: Antibiotic effective against E coli, Salmonella and clostridium spp Category: Antibiotic, oral treatment
  • 10.  Development of antibiotic resistant species of bacteria Negative Effects
  • 11.  Effects of drug residues in meat  Drug hypersensitivity reaction  Carcinogenic effect  Mutagenic effect  Teratogenic effect  Disruption of Normal Intestinal Flora
  • 12.  Reduce normal microbiota making the bird more susceptible to pathogens  Weaken the immune system, compromise liver function and impair performance.  Aminoglycosides and sulpphonamides can compromise kidney function and impair mineral absorption Negative effects contd.
  • 13.  Only give antibiotics to animals under veterinary supervision.  Not use antibiotics for growth promotion or to prevent diseases in healthy animals.  Vaccinate animals to reduce the need for antibiotics and use alternatives to antibiotics when available.  Promote and apply good practices at all steps of production and processing of foods from animal and plant sources.  Improve biosecurity on farms and prevent infections through improved hygiene and animal welfare. WHO Response
  • 14.  Probiotics (Ex; Lactobacillus, Saccharomyces)  Prebiotics (Ex; Biolex MB)  Enzymes (Ex; Xylenes, amylase, protease combination)  Organic acids (Ex; Citric acid, Formic acid)  Bacteriocins (Ex; Albusin-B)  Bacteriophages  Phytogenic feed additives(Ex; Cinnamon, Fever tea, Garlic, Black pepper)  Essential oils (Ex; thymol, trans cinnamaldehyde, eugenol)  Nanoparticles (Ex; Ag, Cu) Alternatives
  • 15.  Animal Diseases Act No. 59  Ban of all antibiotics as growth promoters and in medicated feed  Stop issuing of license to import antibiotics (2019 onward)  Completely stop usage of antibiotics in livestock by 2022 Government Regulation
  • 16.  Mehdi. Y. (2018), “Use of antibiotics in broiler production: Global impacts and alternatives”  Beyene. T. (2015), “Veterinary Drug Residues in Food- animal Products: Its Risk Factors and Potential Effects on Public Health”  http://www.who.int/news-room/fact- sheets/detail/antibiotic-resistance References

Editor's Notes

  1. They may either kill or inhibit the growth of bacteria.
  2. Therapeutic, batch if one infected, preventive
  3. a substance which is able to transport particular ions across a lipid membrane in a cell.
  4. Enrofloxacin - fluoroquinolones
  5. www.biomin.net/en/articles/negative-effects-of-antibiotics-on-production-and-viable-alternatives/ Reduce normal microbiota including commensal gut microbes that produce bacteriocins making the bird more susceptible to opportunistic pathogens The destruction of large amounts of gram negative bacteria and the subsequent release of endotoxins can weaken the immune system, compromise liver function and impair performance. Aminoglycosides and sulpphonamides can compromise kidney function and impair mineral absorption
  6. Consumers' pressure and worries towards harmful effects of antibiotic use and the ban of antibiotics in EU have promp ted re- searchers to think about alternatives to antibiotics (Diarra and Malouin, 20 1 4). The aim of these alternativ es is to maintain a low mortality rat e, a good level of animal yield while preserving envi- ronment and consumer health. Much research has been carried out to look for natural agents with similar beneficial effects of gro wth promot ers. There are indeed a number of non-therapeutic alter - natives that can substitute antibiotics use. Among these, the most popular are probiotics, prebiotics, enzymes, organic acids, immu- nostimulants, bacteriocins, bacteriophages, ph ytogenic feed addi- tives, phytoc ides, nanoparticles and essential Oils.