The document summarizes key aspects of protein synthesis, including the roles of initiation, elongation, and termination factors. Many factors involved are GTP-binding proteins whose conformations change depending on whether GTP or GDP is bound. Guanine nucleotide exchange factors (GEFs) stimulate the release of GDP and binding of GTP to reactivate GTP-binding proteins. Initiation requires initiation factors IF-1, IF-2, and IF-3. Elongation involves elongation factors EF-Tu, EF-Ts, and EF-G, which are GTP-binding proteins that deliver aminoacyl-tRNAs and catalyze translocation.