Total Physical Response (TPR) is a language teaching method where learners listen to instructions in the target language and perform physical actions. It is based on the belief that language is learned most effectively by comprehending language without pressure to produce it. Key principles of TPR include using movement to enhance memory, imperatives to provide instruction, and developing comprehension before production. TPR has advantages like being memorable and engaging for kinesthetic learners, but has limitations for teaching abstract concepts and prioritizing receptive over productive skills.