The document discusses the importance of systems thinking to address crises related to water, energy, food, and the environment. It notes that food, fuel, and fertilizer crises have occurred repeatedly in recent years due to their interconnected nature. Climate change is exacerbating challenges across these systems. The Nexus Gains initiative aims to develop innovations and governance approaches to strengthen cross-sectoral integration and boost the resilience of these linked systems through various workstreams. Scenario analyses show the potential impacts of policies like fossil fuel taxes on hunger, unmet water needs, and other outcomes across different world regions.