The Renaissance began in Italy in the 13th century as Christian art broke from medieval conventions. Interest grew in human emotion and the human form. By the 15th century, art reflected more detailed observation of anatomy, perspective, and the natural world. Humanism and Neo-Platonism philosophy developed, seeking to reconcile pagan ideals of beauty with Christianity. The Renaissance reached its peak in the early 16th century under artists like Michelangelo and Raphael in Rome.