Blood-derived Stem Cells for Superficial Digital Flexor Tendon Injuries in Horses
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This document discusses using blood-derived stem cell treatment for superficial digital flexor tendon injuries in horses. The treatment involves collecting a blood sample from a horse's lower limbs, isolating the nucleated blood cell fraction, incubating the cells to stimulate growth, and then injecting the grown cells into the injured tendon site. A study found that after 3-6 months, horses that received the stem cell treatment showed excellent regeneration of new tendon tissue compared to their condition at the time of diagnosis based on ultrasound images. The treatment can quickly repair tendon injuries by regenerating new, high quality tissue.
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This document describes a new bioinformatic procedure for identifying the genetic basis of physiological processes in non-model species. The procedure is illustrated by identifying genes involved in cold-induced angiogenesis in carp, a non-model species. The strategy uses ortholog prediction between carp, zebrafish and human to link carp DNA sequences to known angiogenic genes. Conditioned stepped reciprocal best hit BLAST analysis was found to be the most effective ortholog assignment method. Applying this strategy to carp gene expression data identified 135 candidate genes involved in cold-induced angiogenesis, 12 of which were examined in more detail.
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This document discusses platelet rich plasma (PRP), its history and uses, mechanisms of action, and clinical evidence. Some key points:
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Orthobiologics is a current terminology for the application of various cells, cytokines, growth factors.Tissue Engineering,Gene Therapy,Osteoarthritis,Avascular Necrosis,Sickle Cell Disease,Disc Regeneration,PRP,Autologous Chondrocyte Transplantation,BMAC,Spinal cord Injury paraplegia,Autoimmnune disorders,Diabetic foot,Tendinopathies,Wound Healing,,SCAFFOLDS IN STEM CELL THERAPY.Regenerative medicine is now an recognized specialty which has evolved from degerative diseases of Orthopaedic Surgery.Articular Cartilage : Repair To Regenerate To Replace Dr.Sandeep C Agrawal Agrasen Hospital Gondia India www.agrasenortho.com
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Adult Stem cells in Orthopaedics
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Παρουσίαση του Δρ. Σταύρου Αλευρογιάννη που έγινε στο ξενοδοχείο Χίλτον, στις 12/06/15 στα πλαίσια Ημερίδας της Ελληνικής Εταιρείας Αναγεννητικής Ιατρικής, Αντιγήρανσης και Βιοτεχνολογίας, στο 41ο Πανελλήνιο Ιατρικό Συνέδριο.
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Orthobiologics is a current terminology for the application of various cells, cytokines, growth factors.Tissue Engineering,Gene Therapy,Osteoarthritis,Avascular Necrosis,Sickle Cell Disease,Disc Regeneration,PRP,Autologous Chondrocyte Transplantation,BMAC,Spinal cord Injury paraplegia,Autoimmnune disorders,Diabetic foot,Tendinopathies,Wound Healing,,SCAFFOLDS IN STEM CELL THERAPY.Regenerative medicine is now an recognized specialty which has evolved from degerative diseases of Orthopaedic Surgery.Articular Cartilage : Repair To Regenerate To Replace Dr.Sandeep C Agrawal Agrasen Hospital Gondia India www.agrasenortho.com
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Stem cell
Stem cells are cells that can differentiate into other types of cells and can self-renew to produce more stem cells. There are two main types: embryonic stem cells, which are pluripotent and found in early stage embryos, and somatic or adult stem cells, which are multipotent and found in adult tissues. Stem cells are studied for their potential uses such as regenerating damaged tissues to treat diseases like diabetes or paralysis.
Properties and uses of stem cells
A stem cell is a "blank" cell that can give rise to multiple tissue types such as a skin, muscle, or nerve cell.
Under certain physiologic or experimental conditions, they can be induced to become tissue- or organ-specific cells with special functions.
Biological Presentation On Stem Cells
The document discusses different types of stem cells including adult stem cells, fetal stem cells, and embryonic stem cells. It notes that adult stem cell research has had 74 clinical successes in treating various diseases and conditions, while embryonic stem cell research has had no successes and risks tumor formation. The document raises ethical issues with extracting stem cells from embryos and fetuses as it requires their destruction. It concludes that adult stem cells are a promising research area that avoids ethical issues.
Stem cell therapy
Stem cells are undifferentiated cells that can differentiate into specialized cells and can self-renew. There are several types of stem cells including embryonic, adult, and fetal stem cells. Embryonic stem cells are the most versatile but also raise ethical issues, while adult stem cells are more limited in their differentiation potential. Stem cell therapy works by stem cells differentiating into the type of cells needed to repair damaged tissue when transplanted into the body. Current applications of stem cell therapy include treating diseases like cancer, diabetes, and Parkinson's disease.
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- 1. Blood-derived Stem Cells for Superficial Digital Flexor Tendon Injuries in Horses ELLAINE SUGIAN
- 2. Superficial Digital Flexor Tendon (SDFT) Superficial Digital Flexor Tendon Injuries in Racehorses. Also common in show jumping, endurance riding, and dressage Treatments include retirement, medication, therapy and surgery Blood-Derived Stem Cell Treatment can repair tendon injuries by quickly regenerating new quality tissue
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- 4. Study Results Citation • Images a, c, and e are horses 1, 2, and 3 on the day of diagnosis • Images b and d are horse 1 and 2 after 3 months • Image f is horse 3 after 6 months “EXCELLENT ADVENTURES IN THE GAME or how i turned my money into bales of hay”. Website. 2011 July 9. Image. <http://waytintotheraces.blogspot.com/2011/07/brave- monarch-retired.html> Fiske-Jackson, Andy. “Tendon Injuries in Horses-Treatment and Healing”. Vetsonline. Website. 2014 January 27. Images and text. <http://www.vetsonline.com/ publications/veterinary-times/archives/n-44- 04/tendon-injuries-in-horsesa-a-treatment-and- healing.html#f5>. Dreamstime. Website. Image. <http://www.dreamstime.com/stock-illustration- science-microscope-cartoon-vector-clipart-created- adobe-illustrator-eps-format-illustration-use-web-print- image41776500>. G. Marfe, G. Rotta, et al. “Use of blood-derived stem cells (BDSCs) for superficial digital flexor tendon injuries in horses. 2012. Science Direct.