This document discusses high-speed, high-resolution inspection of flat panel displays. It introduces a distributed image sensor computing system (DISCS) that uses GPUs for parallel processing to enable fast, in-line inspection. The DISCS uses dark-field illumination and line scan cameras for 2D defect detection. Algorithms like binarization and edge detection are implemented on the GPUs. Experimental results on touch panels and glass show inspection of megapixel images in under 3 seconds. Stereoscopic line scanning and moire topography techniques are discussed for 3D surface profiling with nanometer resolution and micrometer depth detection. Phase shifting interferometry is used to extract height maps. The system is designed for industrial inspection and could integrate