Smoking for 5th year 2011
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Tobacco use is responsible for many preventable deaths worldwide each year and results from neurochemical, environmental, and individual factors. Common pharmacological treatments for tobacco dependence include nicotine replacement therapies, bupropion, and varenicline, which work by reducing withdrawal symptoms and cravings. Non-pharmacological interventions such as counseling can also help treat tobacco dependence, and combining pharmacological and non-pharmacological treatments tends to be most effective.
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This document discusses the biological basis of tobacco addiction and implications for treatment. It begins by explaining why people begin abusing drugs, such as for pleasure, stress relief, or peer pressure. It then defines addiction and dependence, outlining the diagnostic criteria. The document discusses how nicotine acts in the brain through acetylcholine receptors to stimulate the reward pathway. Genetic and conditioning factors that contribute to addiction are also reviewed. The text closes by summarizing withdrawal symptoms and different pharmacological treatments used to aid smoking cessation.
Teenagers With Addictive Behaviors Delana Frazier1
This document discusses addictive behaviors in teenagers and treatment options. It covers epidemiology of substance use in Texas teenagers, pathogenesis and progression of addiction, risk factors, clinical presentation, guidelines for smoking cessation and treatment, and pharmacotherapy options like nicotine replacement therapies. Treatment for addictive behaviors involves counseling, medication, and referral to intensive inpatient programs when needed. Outpatient therapy can effectively treat tobacco addiction in teenagers.
Blackbox(englisch)
Knowledge has been gathered from ten years of interdisciplinary addiction research as well as from two years of experience of the first German Alcohol and Baclofen Forum. This brochure aims at giving an overview of the present state of treatment methods of addiction, anxiety, and depression.
This „Blackbox“ and the matching „Whitebox“ contain more than forty authentic user reports covering their experiences over a period of 6 to 24 months. They provide a clear picture:
„The End of my Addiction“ remains no longer solely the individual experience of a French cardiologist (O. Ameisen, 2004). Moreover it is the reality as experienced by numerous patients and the doctors who treat them – out of necessity – relying on „off- label-use“.
recent advances in smoking cessation
Dr. Priyanka Kumawat presented on smoking cessation treatments. Key points:
1) Quitting smoking reduces health risks but is difficult due to nicotine addiction. Over 1 billion people smoke worldwide and smoking causes many cancers and pulmonary/cardiovascular diseases.
2) FDA-approved smoking cessation treatments include nicotine replacement therapies, bupropion, and varenicline. Emerging treatments include e-cigarettes, vaccines, and drugs targeting nicotine receptors or withdrawal symptoms.
3) All smokers trying to quit should be offered medication. Higher doses of nicotine replacements may help highly dependent smokers. Second-line drugs like clonidine may help those unable to use first-line
Anticraving drugs its efficacy & evidence
This document discusses medications used to treat addiction and prevent relapse. It describes three pathways of alcohol craving and medications like naltrexone, acamprosate, and disulfiram that are used to treat alcohol dependence. Naltrexone and acamprosate have different mechanisms of action and combining them may increase treatment effectiveness. Other medications discussed for various addictions include bupropion for nicotine addiction, varenicline for smoking cessation, rimonabant for reducing cravings, and baclofen and disulfiram for cocaine addiction. The document provides details on the mechanisms, efficacy evidence and side effects of these various pharmacological treatments.
NicoNixRx White Paper
NicoNixRx is a topical smoking cessation cream formulated by Trinity Medical Pharmacy using FDA-approved ingredients. It is a first-of-its-kind transdermal therapy that aims to suppress nicotine withdrawal symptoms through a multi-modal approach, combining antidepressants like SSRIs, TCAs, and atypical agents in one simple topical formula. This novel therapy has advantages over other smoking cessation treatments by potentially eliminating systemic side effects through limited dermal absorption while targeting withdrawal symptoms through multiple neurological pathways. Clinical studies are still needed to demonstrate the safety and efficacy of this compounded drug therapy.
Tob control 2012-aveyard-252-7
This document discusses approaches to improving smoking cessation at the individual level. It first explains that smoking is an addiction and describes withdrawal symptoms experienced when trying to quit. The two main approaches to assisting cessation are pharmacotherapy and behavioral support. Pharmacotherapy such as nicotine replacement therapy, bupropion, and varenicline can help reduce urges to smoke and withdrawal symptoms. Behavioral support aims to boost motivation and develop skills to avoid smoking. The document argues that treating tobacco addiction and assisting with cessation should be part of medical treatment due to the health risks of smoking.
Improving smoking cessation approaches at the individual level
This document discusses approaches to improving smoking cessation at the individual level. It first explains that smoking is an addiction and describes withdrawal symptoms experienced when trying to quit. The two main approaches to assisting cessation are pharmacotherapy and behavioral support. Pharmacotherapy such as nicotine replacement therapy, bupropion, and varenicline can help reduce urges to smoke and withdrawal symptoms. Behavioral support aims to boost motivation and develop skills to avoid smoking. The document argues that treating tobacco addiction and assisting with cessation should be part of medical treatment due to the health risks of smoking.
Electronic smoking
This document discusses the health effects of smoking and provides information on smoking cessation. Some key points:
1) Smoking significantly increases the risk of developing respiratory diseases and cancer, and over half of respiratory disease deaths are due to smoking. The risks diminish rapidly after quitting.
2) Nicotine replacement therapies like patches, gum, and lozenges can help reduce withdrawal symptoms and increase success rates for quitting. Bupropion is also used as a non-nicotine oral therapy.
3) Electronic nicotine delivery systems (ENDS) like e-cigarettes are increasingly popular but their long-term safety is still unknown. While they may contain fewer toxicants than cigarettes, health risks may
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Effective treatment for drug addiction in Mindheal Homeopathy clinic ,Chembur...
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Teenagers With Addictive Behaviors Delana Frazier1
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Improving smoking cessation approaches at the individual level
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Dietary fiber from whole foods like grains, legumes, vegetables, and fruits has demonstrated benefits for gastrointestinal (GIT) health. Isolated and extracted fibers also show promising regulatory effects on the gut and microbiome. However, fibers have varying physicochemical properties depending on their origin and processing that influence their functional characteristics and clinical applications. More research is needed, including well-designed randomized controlled trials, to determine which fiber sources, characteristics, doses and durations optimize GIT health benefits and manage gastrointestinal disorders. Combining fibers with different physiological effects may be a promising therapeutic strategy.
Med j club mm covid20
- Coronaviruses typically cause common colds but SARS-CoV and MERS-CoV can cause pneumonia, respiratory failure, and death. A novel coronavirus, SARS-CoV-2, emerged in Wuhan, China in late 2019 and caused a global pandemic.
- SARS-CoV-2 spreads mainly through respiratory droplets when people cough, sneeze or talk within 6 feet of each other. Asymptomatic and pre-symptomatic people are highly infectious.
- COVID-19 symptoms range from mild to critical illness. The elderly and those with pre-existing conditions are at higher risk for severe disease. Diagnosis involves PCR testing of respiratory samples.
GIT J Club IBD- sexual dysfunction20.
- Sexual dysfunction and infertility are more prevalent in men with IBD compared to the general population.
- Depression is the most consistent negative predictive factor of sexual function among men with IBD.
- Sulfasalazine can reversibly reduce male fertility, so it is recommended to discontinue 3-4 months prior to conception. Most other IBD medications do not significantly impact fertility.
- Men with IBD have an increased risk of prostate cancer and prostate cancer screening guidelines for higher risk patients should be followed.
GIT J Club IBD- pregnancy2020
The document summarizes a consensus clinical care pathway for women with inflammatory bowel disease (IBD) who are considering pregnancy or are pregnant. The pathway was created by an expert multidisciplinary team representing multiple societies to provide standardized, evidence-based recommendations for gastroenterology and obstetric providers to ensure healthy pregnancies for women with IBD. It addresses the lack of consistent advice available previously by compiling available data on therapeutic options for IBD that have increased over the last 15 years and putting them into an easily accessible format for clinical practice.
Med 5th geriatrics20
This document provides an overview of geriatrics and common issues in caring for elderly patients. It discusses how biological age is more important than chronological age in clinical decision making. Frailty and disability are also addressed. Common geriatric problems like falls, delirium, incontinence and adverse drug reactions are examined in terms of presentation, evaluation, and management strategies. The importance of a comprehensive assessment, considering multiple comorbidities and functional status, is emphasized in developing treatment plans for elderly patients.
GIT 4th abd wall pain
Here are the answers to the CME questions:
1. b
2. e
3. a
4. b
5. d
6. b
7. Inguinal hernias
8. E
GIT 4th endoscopy indications20
Upper and lower GI endoscopies have diagnostic, therapeutic, and screening indications. For upper endoscopy, common diagnostic indications include dyspepsia in patients over age 60 or with red flags, upper GI bleeding, and dysphagia. Therapeutic uses include treatment of bleeding, removal of foreign bodies, dilation of strictures, and stenting. Screening is done for portal hypertension, Barrett's esophagus, eosinophilic esophagitis, and cancers. Lower endoscopy indications involve diagnostic evaluation of bleeding, abdominal pain, diarrhea, and screening of average-risk adults over 50 and high-risk groups. Therapeutic colonoscopy is used for polypectomy, bleeding treatment, and stricture dilation
GIT J Club from UEG Week 2018.
Dr. Hiwa Abubakir and Dr. Mohamed Alshekhani discuss the management of nonvariceal gastrointestinal bleeding. They recommend endoscopy within 24 hours, or earlier for high-risk patients, to identify and treat the bleeding source. A variety of endoscopic tools can be used for hemostasis, including injection of adrenaline combined with clips, bands, electrocautery, or laser coagulation. Newer tools like over-the-scope clips are best for high-risk or recurrent bleeders. Doppler probes help ensure complete vessel occlusion. Additional prothrombotic agents or interventions may be needed in some cases.
Med j club dm antithrombosis19
The document discusses antithrombotic strategies for patients with diabetes who are at risk of cardiovascular events. It proposes strategies for primary prevention, stable coronary artery disease, acute coronary syndromes, ischemic stroke, peripheral artery disease, atrial fibrillation, and venous thromboembolism. More aggressive antithrombotic therapies are associated with greater reduction in recurrent cardiovascular events for patients with diabetes. However, these strategies must be weighed against the risk of bleeding. Further clinical trials are still needed to better understand optimal antithrombotic treatment for cardiovascular patients with diabetes.
Git 4th GC18.
1) Gastric carcinoma is the third leading cause of cancer death worldwide, with highest incidence in East Asia and parts of South America.
2) Risk factors include H. pylori infection, smoking, diet high in salted/preserved foods, and family history of gastric cancer.
3) Early detection through endoscopy in dyspeptic patients over 50 years old or with red flags can improve outcomes, as resection allows for potential cure in early gastric cancer confined to mucosa or submucosa.
GIT J Club IBS NEJM17.
This document summarizes guidelines for the diagnosis and management of irritable bowel syndrome (IBS). It defines IBS and its subtypes based on the Rome IV criteria. It recommends diagnosing IBS based on symptoms in the absence of alarm features or abnormal test results. Limited testing like fecal calprotectin can help distinguish IBS from inflammatory bowel disease. Treatment involves dietary changes, probiotics, antispasmodics, antidepressants, and targeted therapies depending on IBS subtype and predominant symptoms. For refractory cases, a multidisciplinary approach including psychological support may help manage persistent symptoms.
GIT 4th indication for upper GI endoscopy.
Upper gastrointestinal endoscopy has diagnostic, therapeutic, and screening indications. Diagnostically, it is used to detect diseases causing dyspepsia like gastric cancer, investigate upper GI bleeding, diagnose dysphagia, remove foreign bodies, assess GERD, detect esophageal varices, and diagnose celiac disease. Therapeutically, it treats upper GI bleeding, removes foreign bodies, dilates strictures, treats achalasia, places stents, treats GERD, eradicates Barrett's esophagus, inserts feeding tubes, and performs bariatric procedures. Screening indications include detecting Barrett's esophagus, portal hypertension, and cancers of the esophagus and stomach in high-risk patients
GIT Cholestatic AI HBD 17
The document discusses various autoimmune and cholestatic liver diseases including primary biliary cholangitis, primary sclerosing cholangitis, and intrahepatic cholestasis of pregnancy. It provides details on the epidemiology, clinical features, diagnosis, and management of these conditions. It also includes several multiple choice questions to test understanding of topics covered in the document.
GiIT 4th CRC 2017.
- Screening and surveillance are recommended for CRC starting at age 50 to detect and remove precancerous polyps through colonoscopy.
Git j club colonoscopy mistakes.
1. The document outlines 19 potential mistakes that can occur during colonoscopy procedures. These include doing colonoscopies without proper indications or patient evaluation, failing to adequately prepare the colon, misdiagnosing conditions like ulcerative colitis or hemorrhoids, not performing important parts of the exam like ileal intubation or biopsies, and not adhering to quality standards. Addressing these issues can help improve safety, accuracy of diagnoses, and overall quality of colonoscopy.
GIT 4th ibd 2017
This document provides an overview of inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. It discusses risk factors, clinical manifestations, diagnostic testing, and treatment approaches. The main points are:
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- Genetic and environmental factors contribute to risk. Smoking increases risk for Crohn's but decreases risk for ulcerative colitis.
- Symptoms vary based on disease location but may include abdominal pain, diarrhea, bleeding, weight loss, and nutritional deficiencies. Extraintestinal manifestations are more common with Crohn's.
GIT 4th IBS 2017
This document provides information on irritable bowel syndrome (IBS), including its definition, diagnostic criteria, subtypes, differential diagnosis, evaluation, and management approaches. Some key points:
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Ppi seminar hiwa.
This document discusses the classical and long-term indications for PPI use, including GERD, Barrett's esophagus, use with NSAIDs, use with anti-platelets, and non-ulcer dyspepsia. For GERD, guidelines recommend daily PPI for erosive esophagitis but intermittent PPI courses may be sufficient for many patients. For Barrett's esophagus, the absolute cancer risk reduction with daily PPI is low. For NSAID and anti-platelet users at high risk of bleeding, the benefits of daily PPI are well documented. Intermittent PPI courses are often sufficient for non-ulcer dyspepsia, though some patients may require long-
Ppi symposium araz.
This document discusses potential long-term side effects of PPI use including increased risk of dementia, chronic kidney disease, and fractures. It notes that the evidence for associations between PPI use and these conditions is not conclusive. The document advises using the lowest effective dose of PPIs for indicated conditions and avoiding long-term daily use when possible. It also stresses the importance of only prescribing PPIs for appropriate indications and discontinuing them when no clear benefit exists.
Ppi symposium muhsin
The document summarizes short-term side effects of PPIs (proton pump inhibitors), which are generally well tolerated. The most common side effects are headache, diarrhea, abdominal pain and nausea. Diarrhea appears to be related to acid suppression and the overall incidence is less than 5%, though it may be dosage and age related. PPIs are considered safe for short-term use and have similar safety profiles to H2 blockers. PPIs should be used cautiously in patients with liver disease.
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