Cardiovascular morbidity and mortality as a result of tobacco products continues to be a global healthcare crisis, particularly in low- and middle-income nations. tobacco products continue to evolve faster than the scientific understanding of their biological effects posing fresh challenges.
When tobacco is burned, a complex chemical mixture of more than 7,000 compounds is produced, many of which are causally associated with premature deaths and diseases affecting nearly every organ system in the body. Even brief exposure to parental and peers smoke sets in permanent adverse biological changes in children. None of the tobacco products is safe and there is no minimum threshold below which tobacco is safe.
Coauthors: Dr Christa Maria Joel, Dr Hira Zahid, Dr Michael Oludipe, Dr Qudroh, Dr Gilda Philip, Ms Philo Mary Fernandez
Module: Effects of Lifestyle on Health
Supervisors: Ms Jane Tobias and Dr Daniel Boakye
University of the West of Scotland
Cardiovascular morbidity and mortality as a result of tobacco products continues to be a global healthcare crisis, particularly in low- and middle-income nations. tobacco products continue to evolve faster than the scientific understanding of their biological effects posing fresh challenges.
When tobacco is burned, a complex chemical mixture of more than 7,000 compounds is produced, many of which are causally associated with premature deaths and diseases affecting nearly every organ system in the body. Even brief exposure to parental and peers smoke sets in permanent adverse biological changes in children. None of the tobacco products is safe and there is no minimum threshold below which tobacco is safe.
Coauthors: Dr Christa Maria Joel, Dr Hira Zahid, Dr Michael Oludipe, Dr Qudroh, Dr Gilda Philip, Ms Philo Mary Fernandez
Module: Effects of Lifestyle on Health
Supervisors: Ms Jane Tobias and Dr Daniel Boakye
University of the West of Scotland
Discover the effects of smoking on your finances,society,health,environment and unborn baby.These slides will open your eyes to the harmful effects of tobacco,so,much so that you won't want to touch it again.
GPCS organised a short awareness programme on World No Tobacco Day on 31st May 2021. Apart from 31 NCC Cadets, more than 50 senior students were also present. The programme was concluded with Pledge taking movement.
It gives insight into why tobacco smoking is harful and what strategies one should adpot to quit smoking. Some interesting snapshots makes the point clear to all
Discover the effects of smoking on your finances,society,health,environment and unborn baby.These slides will open your eyes to the harmful effects of tobacco,so,much so that you won't want to touch it again.
GPCS organised a short awareness programme on World No Tobacco Day on 31st May 2021. Apart from 31 NCC Cadets, more than 50 senior students were also present. The programme was concluded with Pledge taking movement.
It gives insight into why tobacco smoking is harful and what strategies one should adpot to quit smoking. Some interesting snapshots makes the point clear to all
"Quitting Smoking: Your Journey to a Healthier Life"
Embarking on the journey to quit smoking is not just a decision; it's a transformational commitment to reclaiming your health and vitality. In this insightful publication, we delve into the multifaceted process of quitting smoking, offering comprehensive guidance and support every step of the way.
From understanding the psychological and physical dependencies to implementing effective cessation strategies, each page is a roadmap to success. Discover practical tips for managing cravings, navigating withdrawal symptoms, and cultivating a mindset of resilience. Through personal stories, expert insights, and evidence-based techniques, this publication empowers you to break free from the grip of tobacco addiction and embrace a smoke-free future.
Join the millions who have embarked on this life-changing journey and experience the profound benefits of quitting smoking. Your health, happiness, and longevity await.
health publications :
These “basic six” services were: vital statistics, communicable disease control, environmental sanitation, public health laboratory services, maternal and child health services, and public health education
Tobacco . Its definition, available forms , fatal dose , contents , pathophysiology , pharmacokinetics and toxicology. Diagnosis and treatment of toxicity.
Everolimus eluting stents or bypass surgery finalGOPAL GHOSH
Trials and registry studies have shown lower long-term mortality after CABG than after PCI among patients with multivessel disease.These previous analyses did not evaluate PCI with second-generation drug-eluting stents
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
2. Definition
• Never Smokers – Adults who have never smoked a
cigarette or who smoked fewer than 100 cigarettes in their
entire lifetime.
• Former Smokers – Adults who have smoked at least 100
cigarettes in their lifetime, but say they currently do not
smoke.
• Nonsmokers – Adults who currently do not smoke
cigarettes, including both former smokers and never smokers.
• Current Smokers – Adults who have smoked 100
cigarettes in their lifetime and currently smoke cigarettes every
day (daily) or some days (nondaily).
http://dhds.cdc.gov/guides/healthtopics/indicator
3.
4.
5. FACTORS?
• Cigarette smoke contains over 4,000 known
components, of which only a few components
have been examined in isolation
Carbon monoxide (CO)
Polycyclic aromatic hydrocarbons found in the tar
fraction
Nicotine
Free radical-mediated oxidative stress(Currently
most accepted hypothesis)
6. Effects
• Cigarette smoking predisposes the individual to
several different clinical atherosclerotic syndromes,
including stable angina, acute coronary syndromes,
sudden death, and stroke. Aortic and peripheral
atherosclerosis are also increased.
7. Hung MJ, Hu P, Hung MY. Coronary Artery Spasm: Review and
Update. Int J Med Sci 2014; 11(11):1161-1171
8. • Passive smoking (environmental tobacco exposure)
with a smoke exposure about one-hundredth that of
active CS is associated with approximately a 30%
increase in risk of CAD, compared with an 80%
increase in active smokers