This document discusses the role of rasa dravyas (herbo-mineral substances) in the treatment of Madhumeha (diabetes mellitus). It begins with an introduction on Madhumeha and the use of rasa dravyas in Ayurveda. It then discusses various rasa dravyas like Abhraka, Vaikrantha, Makshika, etc. and their properties. It also mentions several classical and patent Ayurvedic formulations used to treat Madhumeha. It reviews some research works on specific rasa dravyas and their effects on blood glucose and lipids. The discussion concludes that Madhumeha is considered incurable but rasa dravyas can provide benefits in its