Fungi can reproduce both sexually and asexually. Asexual reproduction is more common and occurs through fragmentation, fission, budding or sporulation. Sporulation produces spores like sporangiospores or conidia. Sexual reproduction involves the union of nuclei through plasmogamy and karyogamy, followed by meiosis. It occurs via processes like planogametic copulation, gametangial contact or somatogamy and produces offspring through recombination of genetic material.
Bacteria are microscopic, single-celled organisms that thrive in diverse environments. These organisms can live in soil, the ocean and inside the human gut. Humans' relationship with bacteria is complex. Sometimes bacteria lend us a helping hand, such as by curdling milk into yogurt or helping with our digestion.
The algae reproduce by vegetative, asexual, and sexual methods. Vegetative reproduction is by fragmentation, where each fragment develops into a thallus. Asexual reproduction is by the production of flagellated zoospores which on germination give rise to new plants.
Bacteria are microscopic, single-celled organisms that thrive in diverse environments. These organisms can live in soil, the ocean and inside the human gut. Humans' relationship with bacteria is complex. Sometimes bacteria lend us a helping hand, such as by curdling milk into yogurt or helping with our digestion.
The algae reproduce by vegetative, asexual, and sexual methods. Vegetative reproduction is by fragmentation, where each fragment develops into a thallus. Asexual reproduction is by the production of flagellated zoospores which on germination give rise to new plants.
The plant body in algae is always a thallus. It is not differentiated in root, stem and leaves. Algae range in size from minute unicellular plants (less than 1 µ in diameter in some planktons) to very large highly differentiated multicellular forms e.g., some sea-weeds.
Their forms may be colonial (loose or integrated by inter-connections of protoplasmic strands), filamentous (branched or un-branched), septate (branched or un-branched), non-septate or branched, multinucleate siphonaceous tube where the nuclear divisions occur without usual septa formation.
Fungi are a kingdom of usually multicellular eukaryotic organisms that are heterotrophs (cannot make their own food) and have important roles in nutrient cycling in an ecosystem. Fungi reproduce both sexually and asexually, and they also have symbiotic associations with plants and bacteria.
Fungi get their nutrition by absorbing organic compounds from the environment. Fungi are heterotrophic: they rely solely on carbon obtained from other organisms for their metabolism and nutrition. Fungi have evolved in a way that allows many of them to use a large variety of organic substrates for growth, including simple compounds such as nitrate, ammonia, acetate, or ethanol. Their mode of nutrition defines the role of fungi in their environment.
Fungi obtain nutrients in three different ways:
They decompose dead organic matter. A saprotroph is an organism that obtains its nutrients from non-living organic matter, usually dead and decaying plant or animal matter, by absorbing soluble organic compounds. Saprotrophic fungi play very important roles as recyclers in ecosystem energy flow and biogeochemical cycles. Saprophytic fungi, such as shiitake (Lentinula edodes) and oyster mushrooms (Pleurotus ostreatus), decompose dead plant and animal tissue by releasing enzymes from hyphal tips. In this way, they recycle organic materials back into the surrounding environment. Because of these abilities, fungi are the primary decomposers in forests.
They feed on living hosts. As parasites, fungi live in or on other organisms and get their nutrients from their host. Parasitic fungi use enzymes to break down living tissue, which may cause illness in the host. Disease-causing fungi are parasitic. Recall that parasitism is a type of symbiotic relationship between organisms of different species in which one, the parasite, benefits from a close association with the other, the host, which is harmed.
They live mutualistically with other organisms. Mutualistic fungi live harmlessly with other living organisms. Recall that mutualism is an interaction between individuals of two different species, in which both individuals benefit.
Rhizopus is a genus of common saprophytic fungi on plants and specialized parasites on animals. They are found in a wide variety of organic substances , including "mature fruits and vegetables", jellies, syrups, leather, bread, peanuts, and tobacco.
Introduction,In some fungi ,true sexual cycle comprising of nuclear fusion and meiosis is absent.
These fungi derive the benefits of sexuality through a cycle know as parasexuaL cycle.
First Reported by- Gudio Pontecorvo and J.A.Roper(1952)
Parasexual cycle was reported in
Aspergillus nidulans,the imperfect stage of Emericella nidulans.
Since then parasexual cycle has been discovered not only in several members of Deutromycetes but also in fungi belonging to Ascomycetes and Basidiomycetes.
DEFINETION - Parasexuality is defined as a cycle in which Plasmogamy, Karyogamy and Meiosis [Haploidization] take place in sequence but not at a specified time or at specified points in the life cycle of an organism.
Generally parasexual cycle occurs in those fungi in which true sexual cycle does not take place.
Parasexualcycle also know as Somatic recombination. PASEXUALITY ALSO REPORTED IN SOME ORGANISMS- Aspergillus nigar, Penicillium crysogenum, STEPS OF PARASEXUAL CYCLE - 1) ESTABLISHMENT OF HETEROKARYOSIS, 2) Formation of Heterozygous DIPLOIDS, 3) occasional mitotic crossing-over during multiplication of diploid nuclei, 4)occasional haplodization through aneuploidy , COMPARISION BETWEEN SEXUAL AND PARASEXUAL CYCLE, IMPORTANCE OF PARASEXUALITY, C0NCLUSION
Chlamydomonas is unicellular, motile green algae. In this presentation the systematic position, occurrence, structure and different types of reproduction is being explained. palmella stage in vegetative reproduction is one of the outstanding character found among the other algae.
Asexual reproduction in Fungi -Dr C R MeeraMeera C R
This slideshow describes asexual reproduction methods in fungi in detail. Methods like Fission, Budding, Fragmentation, Spore formation (Asexual spores) are explained in detail. Asexual spores and their formation are well explained with examples.
Classifications of Fungi
Characteristics of all Fungi
Structure of Fungi
Reproduction
Classification of Fungi
Basidiomycota
sexual reproduction occur by basidium , will be present spore is called basidiospore .
Asexual by budding ,fragementation, conidiospores.
Ascomycota
microscopic sexual structure in which nonmotile spores, called ascospores.
Mostly the ascomycota is sexual but some asexual it lacks the ascospore.
Zygomycota
Two spore
mitospores ( or) sporangiospore
chlamitospore (or) zygospore
Deuteromycota
Imperfect Fungi referring to our "imperfect" knowledge of their complete life cycles.
sexual life cycle that is either unknown or absent.
Asexual reproduction is by means of conidia or may be lacking.
culture media
SDA medium – sabouraud dextrose agar
The plant body in algae is always a thallus. It is not differentiated in root, stem and leaves. Algae range in size from minute unicellular plants (less than 1 µ in diameter in some planktons) to very large highly differentiated multicellular forms e.g., some sea-weeds.
Their forms may be colonial (loose or integrated by inter-connections of protoplasmic strands), filamentous (branched or un-branched), septate (branched or un-branched), non-septate or branched, multinucleate siphonaceous tube where the nuclear divisions occur without usual septa formation.
Fungi are a kingdom of usually multicellular eukaryotic organisms that are heterotrophs (cannot make their own food) and have important roles in nutrient cycling in an ecosystem. Fungi reproduce both sexually and asexually, and they also have symbiotic associations with plants and bacteria.
Fungi get their nutrition by absorbing organic compounds from the environment. Fungi are heterotrophic: they rely solely on carbon obtained from other organisms for their metabolism and nutrition. Fungi have evolved in a way that allows many of them to use a large variety of organic substrates for growth, including simple compounds such as nitrate, ammonia, acetate, or ethanol. Their mode of nutrition defines the role of fungi in their environment.
Fungi obtain nutrients in three different ways:
They decompose dead organic matter. A saprotroph is an organism that obtains its nutrients from non-living organic matter, usually dead and decaying plant or animal matter, by absorbing soluble organic compounds. Saprotrophic fungi play very important roles as recyclers in ecosystem energy flow and biogeochemical cycles. Saprophytic fungi, such as shiitake (Lentinula edodes) and oyster mushrooms (Pleurotus ostreatus), decompose dead plant and animal tissue by releasing enzymes from hyphal tips. In this way, they recycle organic materials back into the surrounding environment. Because of these abilities, fungi are the primary decomposers in forests.
They feed on living hosts. As parasites, fungi live in or on other organisms and get their nutrients from their host. Parasitic fungi use enzymes to break down living tissue, which may cause illness in the host. Disease-causing fungi are parasitic. Recall that parasitism is a type of symbiotic relationship between organisms of different species in which one, the parasite, benefits from a close association with the other, the host, which is harmed.
They live mutualistically with other organisms. Mutualistic fungi live harmlessly with other living organisms. Recall that mutualism is an interaction between individuals of two different species, in which both individuals benefit.
Rhizopus is a genus of common saprophytic fungi on plants and specialized parasites on animals. They are found in a wide variety of organic substances , including "mature fruits and vegetables", jellies, syrups, leather, bread, peanuts, and tobacco.
Introduction,In some fungi ,true sexual cycle comprising of nuclear fusion and meiosis is absent.
These fungi derive the benefits of sexuality through a cycle know as parasexuaL cycle.
First Reported by- Gudio Pontecorvo and J.A.Roper(1952)
Parasexual cycle was reported in
Aspergillus nidulans,the imperfect stage of Emericella nidulans.
Since then parasexual cycle has been discovered not only in several members of Deutromycetes but also in fungi belonging to Ascomycetes and Basidiomycetes.
DEFINETION - Parasexuality is defined as a cycle in which Plasmogamy, Karyogamy and Meiosis [Haploidization] take place in sequence but not at a specified time or at specified points in the life cycle of an organism.
Generally parasexual cycle occurs in those fungi in which true sexual cycle does not take place.
Parasexualcycle also know as Somatic recombination. PASEXUALITY ALSO REPORTED IN SOME ORGANISMS- Aspergillus nigar, Penicillium crysogenum, STEPS OF PARASEXUAL CYCLE - 1) ESTABLISHMENT OF HETEROKARYOSIS, 2) Formation of Heterozygous DIPLOIDS, 3) occasional mitotic crossing-over during multiplication of diploid nuclei, 4)occasional haplodization through aneuploidy , COMPARISION BETWEEN SEXUAL AND PARASEXUAL CYCLE, IMPORTANCE OF PARASEXUALITY, C0NCLUSION
Chlamydomonas is unicellular, motile green algae. In this presentation the systematic position, occurrence, structure and different types of reproduction is being explained. palmella stage in vegetative reproduction is one of the outstanding character found among the other algae.
Asexual reproduction in Fungi -Dr C R MeeraMeera C R
This slideshow describes asexual reproduction methods in fungi in detail. Methods like Fission, Budding, Fragmentation, Spore formation (Asexual spores) are explained in detail. Asexual spores and their formation are well explained with examples.
Classifications of Fungi
Characteristics of all Fungi
Structure of Fungi
Reproduction
Classification of Fungi
Basidiomycota
sexual reproduction occur by basidium , will be present spore is called basidiospore .
Asexual by budding ,fragementation, conidiospores.
Ascomycota
microscopic sexual structure in which nonmotile spores, called ascospores.
Mostly the ascomycota is sexual but some asexual it lacks the ascospore.
Zygomycota
Two spore
mitospores ( or) sporangiospore
chlamitospore (or) zygospore
Deuteromycota
Imperfect Fungi referring to our "imperfect" knowledge of their complete life cycles.
sexual life cycle that is either unknown or absent.
Asexual reproduction is by means of conidia or may be lacking.
culture media
SDA medium – sabouraud dextrose agar
Fungi are eukaryotic, spore bearing, achlorophyllous, heterotrophic organisms that generally reproduce sexually and asexually and whose filamentous, branched somatic structures are typically surrounded by cell walls containing chitin or cellulose or both with many organic molecules and exhibiting absorptive nutrition.Fungi frequently reproduce by the formation of spores. A spore is a survival or dispersal unit, consisting of one or a few cells, that is capable of germinating to produce a new hypha. Unlike plant seeds, fungal spores lack an embryo, but contain food reserves needed for germination. Many fungi produce more than one type of spore as part of their life cycles. Fungal spores may be formed via an asexual process involving only mitosis (mitospores), or via a sexual process involving meiosis (meiospores). Sexual and asexual reproduction may require different sets of conditions (e. g., nutrients, temperature, light, moisture).
Described about general characters of fungi which include sexual and asexual reproduction with diagram, so it will be easy for undergraduates to understand the various concepts
Describe in detail about fungi and general characters of fungi and different modifications and reproduction in fungi especially for undergraduate students
Detail description about important fungi that comes under chytridiomycota and zygomycota has been described, gives an idea about fungi and their life cycles under thus groups
REPRODUCTION IN FUNGI
Vegetative Reproduction
-Fission of somatic cell
-Budding of somatic cell
-Fragmentation or disjoining of hypha
Asexual spore formation
-Endospore
-Conidia
-Aplanospores
-Arthrospores/Oidia
-Chlamydomonas
Sexual Reproduction
-Plasmogamy
-Karyogamy
-Meiosis
---Oogamy
---Isogamy and anisogamy
---Spermatization
---Direct union of vegetative hypha and parthenogenesis
SEXUAL SPORES IN FUNGI
i. Ascospore
ii. Basidiospore
iii. Zygospore
iv. Oospore
LIFE CYCLE
--Haploid phase
--Dipload phase
--Haploid and diploid phases
--Dikaryotic phase
Mycology is the branch of biology concerned with the study of fungi.
The word 'myco' is derived from the Greek word mýkēs meaning “mushroom, fungus”.
Heinrich Anton de Bary is the father of Mycology.
Fungi are eukaryotic organisms that include such as yeasts, moulds and mushrooms. These organisms are classified under kingdom fungi.
Fungi are diverse and widespread.
PHARMACEUTICAL MICROBIOLOGY (BP303T) Unit-III Part-1 Study of morphology, cla...Ms. Pooja Bhandare
PHARMACEUTICAL MICROBIOLOGY (BP303T)Unit-IIIPart-1Study of morphology, classification, reproduction/replication and cultivation of fungi, Introduction fungi. Morphological Characteristics of fungi, CLASSIFICATION: Depending on cell morphology, fungi can be divided into 4 classes:
Moulds Yeasts ,Yeast like fungi and
Dimorphic fungi
Depending on their sexual spores formation fungi are divided into 4 classes:
Zygomycetes Ascomycetes
Basidiomycetes Dueteromycetes
Reproduction and sporulation;Vegetative, Asexual
and Sexual
Vegetative reproduction: Fragmentation ,Fission, budding, Sclerotia Rhizomorphs
Asexual reproduction: Zoospores
Sporangiospore, Conidia
Oidia Uredospores ,Basidiospores
Sexual reproduction:Planogametic copulation: Isogamy Heterogamy
Gametangial contact
Gametangial copulation Spermatization Somatogamy CULTIVATION OF FUNGI: Brain Heart Infusion (BHT) agar
Czapek’s agar
Mycobiotic agar Inhibitory mold agar (IMA)
Potato dextrose agar
Sabouraud’s dextrose agar (SDA):
Sabouraud’s heart infusion (SABHI) agar
Potato Flake agar
Potato dextrose-yeast extract agar (PDYA)
. Cornmeal agar
Malt extract agar (MEA)
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
2. REPRODUCTION
• Reproduction is the formation of new individuals
having all the characteristics typical of a species.
• The fungi reproduce by means of asexual and
sexual or parasexual reproduction.
• Asexual reproduction is sometimes called
somatic or vegetative and it does not involve
union of nuclei, sex cells or sex organs.
• The union of two nuclei characterizes sexual
reproduction.
3. ASEXUAL REPRODUCTION
• In fungi, asexual reproduction is more important
for the propagation of species.
• Asexual reproduction does not involve union of
sex organs (gametangia) or sex cells (gametes)
or nuclei.
• It is repeated several times during the life span
of a fungus producing numerous asexual
spores.
4. • In fungi the following are the common methods
of asexual reproduction.
• Hence, it is more important for fungi than sexual
reproduction.
• Asexual spores are formed after mitosis ,hence
also called mitospores.
5. Methods of asexual reproduction
1. Fragmentation .
2. Fission.
3. Budding.
4. Sporulation ( production of spores).
6. 1. Fragmentation
• It is the most common method.
• Hypha of fungus breaks into small pieces, each broken
piece is called a fragment, which function as a
propagating unit and grows into a new mycelium.
• The spores produced by fragmentation are called
arthrospores (arthron = joint) (spora = seed) or
oidia..
• Eg. Oidium, Geotrichum. Sometimes, the contents of
intercalary cells or terminal cells of hypha rounded off
and surrounded by thick wall and formed as
chlamydospores which are thick walled resistant
spores produced either singly or in chains. Eg.
Fusarium oxysporum, Ustilago tritici.
7.
8. 2. Fission / Transverse fission
• The parent cell elongates, nucleus under go
mitotic division and forms two nuclei, then the
contents divide into equal halves by the
formation of a transverse septum and separates
into two daughter cells.
• Eg. Saccharomyces cerevisiae.
9. 3.Budding
• The spores formed through budding are called blastospores.
• The parent cell puts out initially a small out growth called bud
/blastos ie., sprout or out growth which increases in size and
nucleus divides, one daughter nucleus accompanied by a
portion of cytoplasm migrates into bud and the other nucleus
remains in the parent cell.
• Later, the bud increases in size and a constriction is formed at
the base of bud, cutting off completely from parent cell.
• Bud, when separated from parent cell, can function as an
independent propagating unit.
• Sometimes multiple buds are also seen i.e., bud over bud and
looks likepseudomycelium.
• Eg. Saccharomyces cerevisiae.
10.
11. 4. Sporulation ( spores):
• The process of production of spores is called
sporulation.
• Spore: It is a minute, simple propagating unit of
the fungi, functioning as a seed but differs from it
in lacking a preformed embryo that serves in the
reproduction of same species.
• Spores vary in colour, size, number of cells and
the way in which they are borne.
12. There are 2 main types of spores.
1. Sporangiospores
2. Conidia
13. Sporangiospores
• When the asexual spores are produced internally,
within the sporangia, such spores are called
sporangiospores.
• The sac like structure which produces
sporangiospores is called sporangium.
• The special hypha bearing sporangium is called
sporangiophore which may or may not be
distinguishable from hypha.
• A small sporangium with or without columella
containing a few or single spore is called as
sporangiolum.
• Eg. Choanephora trispora.
15. Sporangiospores are of 2 types.
a. Zoospores /planospores
Eg. Pythium, Phytophthora.
b. Aplanospores
Eg. Rhizopus stolonifer, Mucor.
16.
17. 2. Conidia / Conidiospores
• (konis = dust; oides=like)
• Conidia are non- motile asexual spores which may
arise directly from somatic hyphae or from
specialized conidiogenous cells (a cell from which
conidia are produced) or on conidiophore (hypha
which bear conidia).
• Conidia are produced freely on conidiophore ie., at
the tips or sides of conidiophore or may be
produced in specialized asexual fruiting bodies viz.,
pycnidium, acervulus, sporodochium and
synnemata.
20. SEXUAL REPRODUCTION
• Sexual reproduction involves union of two compatible
nuclei or sex cells or sex organs or somatic cells or
somatic hyphae for the formation of new individuals.
• Sexual stage is perfect stage and technically called as
teleomorphic stage.
• Sexual cycle normally occurs once in the life span of
the fungus.
21. Phases in Sexual reproduction
1. Plasmogamy: union of two protoplasts takes
place. As a result of it the two nuclei come together
within the same cell.
2. Karyogamy: union of 2 sexually compatible nuclei
brought together by plasmogamy to form a diploid
nucleus (2n) i.e., zygote.
3. Meiosis: This is reduction division . The number of
chromosomes is reduced to haploid (n) i.e., diploid
nucleus results into haploid nucleus..
22. Methods of sexual reproduction
1. Planogametic copulation.
2. Gametangial contact.
3. Gametangial copulation.
4. Spermatisation.
5. Somatogamy.
23. 1.Planogametic copulation ( gametogamy )
• This involves the union of 2 naked gametes one or both
of which are motile.
a. Isogamy (Isogamous planogametic copulation) : If both
gametes are motile and similar. Eg. Plasmodiophora
brassicae.
b. Anisogamy (Anisogamous planogametic copulation) : If
both gametes are motile but dissimilar. E g. Allomyces
macrogynus
c. Heterogamy: If gametes are dissimilar, one motile,
another is non motile. Eg. Monoblepharis polymorpha.
24. 2.Gametangial contact ( gametangy / oogamy ):
• Male and female gametangia come in contact . At the
place of contact, dissolution of wall occurs and a
fertilization tube is formed.
• The contents of male gametangium migrate into
female gametangium through a pore or fertilization
tube developed at the point of contact.
• The gametangia do not loose their identity.
• Eg. Pythium aphanidermatum.
25.
26. 3.Gametangial copulation ( gametangiogamy )
• The isogametangia come in contact, their intervening
wall dissolves leading to fusion of entire contents of
two contacting gametangia to form a single unit.
• Gametangia loose their identity.
• The protoplasts fuse and the unit increases in size.
• Eg. Rhizopus stolonifer.
28. 4.Spermatization
• Minute, uninucleate male cells called as spermatia
which are produced on spermatiophores in a fruiting
body ( pycnium) are carried to female reproductive
structures called receptive hyphae.
• Spermatia and receptive hyphae come in contact and
contents of male spermatium migrate into female
receptive hypha, thus making the cell binucleate.
• This process is called dikaryotization.
• Eg. Puccinia graminis tritici.
29.
30. 5.Somatogamy
• Many higher fungi do not produce sex organs.
• In such cases somatogamy takes place.
• It is the union of 2 somatic hyphae or somatic cells
representing opposite sexes to form sexual spores.
• Eg. Agaricus campestris.