This document discusses various reconstructive surgery options for restoring form and function after defects in the head and neck region. It outlines a reconstructive ladder ranging from primary closure and skin grafts for small defects, to local and regional flaps, myocutaneous flaps, and free flaps for more complex reconstructions. Key flaps discussed include the pectoralis major flap, fibula flap, radial forearm flap, and anterolateral thigh flap. Patient factors, defect characteristics, and the goal of restoring oral competence, speech, and swallowing are considered in surgical planning. The conclusion emphasizes that reconstructive surgery is essential for improving head and neck cancer survivors' quality of life.
Head and neck cancer reconstruction is arguably the
most challenging area of reconstruction for the reconstructive
surgeon. A clear understanding of the principles of use of local flaps and a comprehensive understanding of the anatomy of these flaps provides the head and neck surgeon with a plethora of local and regional options for primary and secondary reconstruction.
Head and neck cancer reconstruction is arguably the
most challenging area of reconstruction for the reconstructive
surgeon. A clear understanding of the principles of use of local flaps and a comprehensive understanding of the anatomy of these flaps provides the head and neck surgeon with a plethora of local and regional options for primary and secondary reconstruction.
This powerpoint describes the types of maxillectomy & operative steps for total maxillectomy. It also enumerates various flaps used for reconstruction of maxillectomy defect.
This powerpoint describes the types of maxillectomy & operative steps for total maxillectomy. It also enumerates various flaps used for reconstruction of maxillectomy defect.
Advantages of Cervicofial flaps :
Operative time is short.
It causes minimum deviations in relations to important structures around cheek.
reduce surgical risk in high risk patients like old age, diabetic patients, un-controlled hypertension
It can provide excellent skin colour and texture match.
Lecture 2 Facial cosmetic surgery
Maxillofacial Surgery
Dental Students Fifth Year second semester
Al Azhar University Gaza Palestine
Dr. Lama El Banna
https://twitter.com/lama_k_banna
Myringoplasty is the closure of the perforation of pars tensa of the tympanic membrane. When myringoplasty is combined with ossicular reconstruction, it is called tympanoplasty. The operation is performed with the patient supine and face turned to one side.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
How to Give Better Lectures: Some Tips for Doctors
Reconstruction in head and neck surgeries
1.
2. RECONSTRUCTIVE SURGERIES
Aim : Restoration of form and function
Form:
cosmetic
Restoration of contour
Expression of face
Oral competence
Functions:
Speech
Mastication
Deglutition
3. Reconstructive ladder
It consists of following steps starting from simplest to
most complex
Primary closure
Skin grafting
Local flaps
Regional flaps
Distant flaps
Free flaps
4. Patient selection and decision making
Select the most appropriate option for the particular
defect
Patient factors-Age,perfomance
status,comorbidities
Patient choice and expectations
Tissues to be replaced
Occupation
Patient counselling
5. Primary closure
Small and moderate
defects of
Skin
Soft tissues
Mucosa
Should not cause
Restriction of
movements
Tension
Cosmetic disfigurement
6. Skin grafts
For small and superficial
defects of skin and mucosa
Split thickness skin graft
Full thickness skin
grafts
7. Full thickness skin grafts
Ideal for covering small defects
after removal of tumours in areas
like
1. Tip of nose
2. Parts of the pinna
3. Lower eye lid.
Limitation of skin graft:
Colour mismatch,
contour irregularity,
graft contracture
8. Locoregional flaps
Local Flap:
skin flap taken from an
area close to the wound.
E.g.
Abbe transoral cross – Lip flap
A wound on the lip may be
repaired by a flap from the
adjacent cheek.
Eslander flap
Bernad –Burrow flap
9. Local Flaps features:
Rich Vascularity
Lot of local flaps available
Long and thin local flaps can be planned
Good colour and texture match
Good healing of donor site
Less morbidity
Same incision & field
Little expertise
Time saving
10. Regional Flap:
Skin flap is not from the
adjacent area, but is from
the same region of the body.
e.g
Nasolabial flaps
Forehead flaps
Cervical flaps
Submental flaps
11. Submental artery Island Flap
This is an axial pattern flap based on the
submental branch of the facial artery
Advantages:
The donor site scar is hidden
under the mandible.
Flap has a large and reliable
vascular pedicle with excellent
reach to most of the oral cavity.
Ideal thickness for
reconstructing buccal mucosa
and tongue defects.
Less bulk and less time
consuming when compared with
free flaps
12. Disadvantages:
Submental flap harvested with
a thick surrounding fibrofatty
tissue and tissues around the
facial vessels can compromise
the lymphatic clearance. So it
is better to avoid this flap in
patients with clinically
significant node in level IA
and IB.
13. DELTOPECTORAL FLAP
It served as the premier flap for
reconstructing complex head and
neck defects LIKE oral
cavity&cheek
Advantages
Technical simplicity
Predictable vascular supply
The DP flap also provides a
valuable salvage option
The deltopectoral flap is based on
perforators from the internal mammary
artery, usually perforators passing
through the second and third intercostal
spaces.
14. Myocutaneous Flaps
• Commonest reconstructive option for major head
and neck defects
Pectoralis major flaps
Sternomastoid flaps
Trapezius myocutaneous flaps
Latissimuss dorsi flaps
15. Pectoralis major myocutaneous flap
The most frequently used
myocutaneous flap
The workhorse of the head
and neck surgeon
The blood supply to
pectoralis major flap is consistent
and so very reliable.
The donor defect can be
closed primarily in majority of
cases.
16. Main uses of Pectoralis major
Myocutaneous flap
o For reconstruction of major intra oral
lining defects
o For reconstructing outside skin defects
of cheek or full thickness defects of oral
cavity.
o For covering major neck skin defects
following extended radical neck dissection
and in post irradiated patients.
17. o For protecting the exposed carotid vessels following neck
dissection to prevent carotid blow out.
o For augmenting the pharyngeal closure following
laryngopharyngectomy when there is tension in pharyngeal closure
especially in salvage set up.
o For reconstructing circumferential pharyngeal and cervical
oesophageal defects.
18. Platysma flap
Ideal for reconstructing the
superficial lining defects of oral cavity
Disadvantages
Blood supply can be unreliable.
Prior neck dissection or any neck
surgeries precludes the use of this flap
Improper neck dissection may damage
the blood supply to the flap
Removal of the platysma interferes with
the blood supply lead to necrosis of skin.
Platysma flap is not advisable in
patients with prior irradiation to neck.
19. Sternomastoid flap
Advantages
The skin is hairless and thin
An ideal reconstructive option for medium sized cheek
defects.
It does not produce excessive bulk in the face or mouth
Disadvantages
Improper neck dissection is likely to cause damage to
the vascular pedicle.
A previous neck surgery or concurrent
lymphadenectomy preclude the use of this flap
20. Trapezius Myocutaneous Flap
It is used for
reconstructing defects of
head and neck region
and upper back.
Its location makes it
the flap of choice for
defects of the occipital,
parotid and cervical
spine regions.
21. Free Flaps
Features
Pliable so as not to impair
movement in head and neck
Consistent, large and long
pedicle
Possibility of variable size
& thickness
e.g
Radial Forearm flap
Antero lateral Thigh flap
Free Fibula flap
Latissimus Dorsi flap
DCIA flap
TRAM flap
22. MANDIBULAR RECONSTRUCTION
FIBULA FLAP
It consists of the fibula
bone & soft tissues
ADVANTAGES
25 cm of fibula can be
harvested
Extensive periosteal
vascular supply allows
functional reconstruction of the
mandibule
Others
Iliac crest flap
scapular flap
23. CONCLUSION
Reconstructive surgery is an essential part of head and
neck cancer surgery
This improves the form and function of survivors and the
quality of life.
Various options are available for head and neck
reconstructions and has to select the appropriate one