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PRESENTER:
RAHIM GOHAR
Quality assurance of 3-D treatment
planning systems
for external photon and electron beams
Review
IAEA TRS -430
AAPM Task Group- 53
 Canadian Association of Provincial
Cancer Agencies(CAPCA)
overview
 Introduction
 IAEA TRS 430
 Task Group 53
 Canadian Association of Provincial Cancer Agencies(CAPCA)
(2nd part)
 What's going on in the TPS
 Eclipse
 Planning
 Limitations
 Current practices
 What needs to be done???
introduction
 Generally
“Quality assurance, is all those planned and
systematic actions necessary to provide adequate confidence
that a product or service will satisfy the given requirements
for quality (ISO 9000:1994).”
Quality Assurance in Radiotherapy
“QA of a TPS is a dynamic process which evolves with
time”
Purpose
 Proper functioning of TPS
 verification of dose calculations.
 Validation of planning algorithms
 to reduce uncertainties
 reduces the likelihood of accident
 inter-comparison of results
among different radiotherapy
centers,
 Patient safety (End Result)
Reports on QA of TPS
Early reports on QA of TPS
 AAPM Report TG-53
Recent reports on QA of TPS
 IAEA Report
 ESTRO (1998)
Aspects of TPS QA
We can categorize QA tests according to
 System and software
 Configuration process
 Data entry
Evolution of QA of a TPS
 Dynamic process
 Introduction of new software
Tolerances and accuracy
 Accuracy of treatment
 Tolerances in treatment planning http://blog.iactiveit.com/?p=224
Errors in Treatment Planning Process
 Input of patient anatomical data
 Treatment planning system (TPS)
 Dosimetric data for radiation beams
 Dose calculation algorithms
 Geometric data for treatment machines
 Patient and treatment data management & transfer
 Human errors
Quality Assurance in Treatment Planning
 Appropriate program
 Consultants, protocol implementation
 Error identification
 Expertise , mechanism
 Reduce the likelihood of unexpected dosimetric errors
 End Result
BUT……..
Periodic Quality Assurance
After commissioning
 Integrity of
o Hardware, software, data transfer
Upgrading of system
o subset of acceptance tests
Be careful
Some important QC checks
Central processing unit
 Purpose
o To check the functionality of CPU
 Procedure
o Restart or reboot the computer as recommended by the vendor or
as appropriate
o Observe onscreen messages
o Malfunctions(notice if any)
Some important QC checks
Digitizer
 Purpose
o Check the sensitivity, accuracy
 Procedure
 Input any contour of known dimension
 Use screen ruler for verification
 Deviation
 Within 1mm
B
A
1
0
C
6
7
5
D
E
Some important QC checks
Backup recovery
 To confirm that data that have been backed up can be
recovered.
 Restore data that have been recently backed up
 Check the integrity of the restored data.
Some important QC checks
Computed tomography transfer
 Purpose
 To check that CT transfer protocols
have not changed.
 Procedure
 Transfer four basic patient studies
• prone, supine, head first and feet first
Anatomical description
Basic patient entry
 Uniqueness of patient
Image conversion, input and use
 Import, patient orientation
 slice position
Some important QC checks
 Computed tomography density and geometry
 Purpose
 To check that the relationship between the CT number and density and
image geometry has not changed
 Procedure
 Scan a phantom with insertion
of some known density and geometry
 Transfer images to the TPS
 Comparison (0.2cm for distance,
0.02 for electron
density)
Tissue characterization phantom
Reverse verification of HU number
 Hounsfield unit
o Linear transformation attenuation coefficient measurement, by taking
water as reference medium
o Quantitative scale(not SI or derived quantity)
 The CT # of a medium is related to its
attenuation coefficient. They range
from -1000 (air) to “zero” (water) to
1000 (bone):
 H = [(µm - µw) ÷ µw] x 1000
Dosimetric error that would result from the uncertainties from in the HU calibration
Confirmation of the basic beam data
External beam revalidation
 Purpose
 To check the constancy of external beam dose calculations to
safeguard against inadvertent alteration or corruption.
 Procedure
 Check data files
 Review the directory
 Check the creation date
 TPS configuration
 Review calculation model
parameters and check against
the commissioning data.
 Test plans with and without
in-homogeinity
MONITOR UNIT/TIME CHECK
Standard geometrical set up
SSD = 95cm
Depth = 5cm
F.S = 10x10cm2
1 monitor unit =1cGy
Recommissioning or additional data
If a new machine is installed
 update the TPS data
MONITOR UNIT/TIME CHECK
Independent (redundant) check of the MUs/time
 Computer program
 Manual calculation
 Deviation
S
. R
SAD
100
dr
P
SSD
dm
S
Dose uniformity verification at field junction
 Creating junction
 Run the plan on 2-D Array
 Comparison in veri-soft
 Criteria
Photon-Photon field junction
 Beam profile across the junction
BEV
Electron-Electron field junction
 Beam profile across the junction
Electron-photon field junction
 Beam profile across the junction BEV
Electron-photon field junction
Measured electron-photon junction profile
using Gafchromatic films
Dose distribution verification using 2-D Array
Tolerances for the accuracy of photon beam dose calculations
of treatment planning systems
 Objectivity
 Precision
 Machine specific
 Reproducibility
 Accuracy
 Calculation Dependent
 Depends on several factors
Life itself is the second name of uncertainty
Thank you for your attention
Queries??
Comments
Note: “As you sow so shall you Reap”

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Quality assurance of treatment planning system by Rahim Gohar

  • 1. PRESENTER: RAHIM GOHAR Quality assurance of 3-D treatment planning systems for external photon and electron beams Review IAEA TRS -430 AAPM Task Group- 53  Canadian Association of Provincial Cancer Agencies(CAPCA)
  • 2. overview  Introduction  IAEA TRS 430  Task Group 53  Canadian Association of Provincial Cancer Agencies(CAPCA) (2nd part)  What's going on in the TPS  Eclipse  Planning  Limitations  Current practices  What needs to be done???
  • 3. introduction  Generally “Quality assurance, is all those planned and systematic actions necessary to provide adequate confidence that a product or service will satisfy the given requirements for quality (ISO 9000:1994).”
  • 4. Quality Assurance in Radiotherapy “QA of a TPS is a dynamic process which evolves with time” Purpose  Proper functioning of TPS  verification of dose calculations.  Validation of planning algorithms  to reduce uncertainties  reduces the likelihood of accident  inter-comparison of results among different radiotherapy centers,  Patient safety (End Result)
  • 5. Reports on QA of TPS Early reports on QA of TPS  AAPM Report TG-53 Recent reports on QA of TPS  IAEA Report  ESTRO (1998)
  • 6. Aspects of TPS QA We can categorize QA tests according to  System and software  Configuration process  Data entry Evolution of QA of a TPS  Dynamic process  Introduction of new software Tolerances and accuracy  Accuracy of treatment  Tolerances in treatment planning http://blog.iactiveit.com/?p=224
  • 7. Errors in Treatment Planning Process  Input of patient anatomical data  Treatment planning system (TPS)  Dosimetric data for radiation beams  Dose calculation algorithms  Geometric data for treatment machines  Patient and treatment data management & transfer  Human errors
  • 8. Quality Assurance in Treatment Planning  Appropriate program  Consultants, protocol implementation  Error identification  Expertise , mechanism  Reduce the likelihood of unexpected dosimetric errors  End Result BUT……..
  • 9. Periodic Quality Assurance After commissioning  Integrity of o Hardware, software, data transfer Upgrading of system o subset of acceptance tests
  • 11. Some important QC checks Central processing unit  Purpose o To check the functionality of CPU  Procedure o Restart or reboot the computer as recommended by the vendor or as appropriate o Observe onscreen messages o Malfunctions(notice if any)
  • 12. Some important QC checks Digitizer  Purpose o Check the sensitivity, accuracy  Procedure  Input any contour of known dimension  Use screen ruler for verification  Deviation  Within 1mm B A 1 0 C 6 7 5 D E
  • 13. Some important QC checks Backup recovery  To confirm that data that have been backed up can be recovered.  Restore data that have been recently backed up  Check the integrity of the restored data.
  • 14. Some important QC checks Computed tomography transfer  Purpose  To check that CT transfer protocols have not changed.  Procedure  Transfer four basic patient studies • prone, supine, head first and feet first
  • 15. Anatomical description Basic patient entry  Uniqueness of patient Image conversion, input and use  Import, patient orientation  slice position
  • 16. Some important QC checks  Computed tomography density and geometry  Purpose  To check that the relationship between the CT number and density and image geometry has not changed  Procedure  Scan a phantom with insertion of some known density and geometry  Transfer images to the TPS  Comparison (0.2cm for distance, 0.02 for electron density) Tissue characterization phantom
  • 17. Reverse verification of HU number  Hounsfield unit o Linear transformation attenuation coefficient measurement, by taking water as reference medium o Quantitative scale(not SI or derived quantity)  The CT # of a medium is related to its attenuation coefficient. They range from -1000 (air) to “zero” (water) to 1000 (bone):  H = [(µm - µw) ÷ µw] x 1000 Dosimetric error that would result from the uncertainties from in the HU calibration
  • 18. Confirmation of the basic beam data
  • 19. External beam revalidation  Purpose  To check the constancy of external beam dose calculations to safeguard against inadvertent alteration or corruption.  Procedure  Check data files  Review the directory  Check the creation date  TPS configuration  Review calculation model parameters and check against the commissioning data.  Test plans with and without in-homogeinity
  • 20. MONITOR UNIT/TIME CHECK Standard geometrical set up SSD = 95cm Depth = 5cm F.S = 10x10cm2 1 monitor unit =1cGy
  • 21. Recommissioning or additional data If a new machine is installed  update the TPS data
  • 22. MONITOR UNIT/TIME CHECK Independent (redundant) check of the MUs/time  Computer program  Manual calculation  Deviation S . R SAD 100 dr P SSD dm S
  • 23. Dose uniformity verification at field junction  Creating junction  Run the plan on 2-D Array  Comparison in veri-soft  Criteria
  • 24. Photon-Photon field junction  Beam profile across the junction BEV
  • 25. Electron-Electron field junction  Beam profile across the junction
  • 26. Electron-photon field junction  Beam profile across the junction BEV
  • 28. Measured electron-photon junction profile using Gafchromatic films
  • 30. Tolerances for the accuracy of photon beam dose calculations of treatment planning systems  Objectivity  Precision  Machine specific  Reproducibility  Accuracy  Calculation Dependent  Depends on several factors Life itself is the second name of uncertainty
  • 31.
  • 32. Thank you for your attention Queries?? Comments Note: “As you sow so shall you Reap”