Hypertrophic pyloric stenosis occurs when the pyloric sphincter muscle thickens, narrowing the stomach outlet. It typically affects young infants, especially firstborn males. Projectile vomiting after feeding is the main symptom. Diagnosis involves abdominal x-ray or ultrasound showing thickening of the pylorus. Surgical pyloromyotomy is the standard treatment and relieves the obstruction by cutting the thickened muscle. Nursing care focuses on maintaining nutrition, hydration and family support until surgery can be performed.