The document discusses different types of CNS stimulants including analeptics, methylxanthines, central sympathomimetic agents, and antidepressants. It notes that traditional analeptics like picrotoxin and PTZ are potent but non-selective and now obsolete, but used for research. Newer selective agents like modafinil and doxapram are used to treat conditions like narcolepsy and respiratory issues.

2. The CNS stimulants mostly produced a generalized action
which may
Produce convulsion at higher doses.

3. TYPE OF DRUGS NAME OF DRUGS
 ANALEPTICS PICROTOXIN,PENTYLENE
TETRAZOLE,MEDAFINIL,
DOXAZEPAM HYDROCHLORIDE.
 METHYLXANTHINES : CAFFINE,THEOPHYLLENE, THE
OBROMINE.
 CENTRAL SYMPATHOMIMETIC
AGENTS :
AMPHETAMINE,
METHAMPHETAMINE,
PHENTERMINE,BENZOPHETAMI
NE, FENFLURAMINE
 ANTIDEPRESSANTS :
a) MONO AMINE OXIASE INHIBITORS PHENELZINE
SULFATE,TRANYLCYPROMINE
SULFATE
b)TRICYCLIC ANTIDEPRESSANTS IMIPRAMINE,DESIMIPRAMINE,
CLOMIPRAMINE,
AMITRYPTILENE

5. 1.The traditional analeptics are potent and non-selective.
2.They can be illustrated by
a)picrotoxin
& b) PTZ
3.BOTH OF THEM ARE OBSOLATED NOW.
4.But used in research purpose.
5.Newer agents
a)modafinil
& b)doxapram are selective
6.These two are used in narcolepsy and as respiratory
stimulant.

20. References :
1.Wilson & Gisvold’s Organic Medicinal and
Pharmaceutical chemistry
2.Essentials of Medical Pharmacology
-KD TRIPATHY