2. Drugs acting on Nervous system
Drugs acting on Nervous system is classified into:
A.Drug acting on Autonomous Nervous system.
B.Drug acting on central and peripheral nervous
system.
3. Drug acting on Autonomous
Nervous system.
• It is classified into:
1.Cholinergic Drugs.
2.Anticholinergics drugs.
3.Drugs acting on autonomic Ganglia.
4.Adrenergic Drugs [sympathomimetics].
5.Adrenergic Receptor Antagonists/
Antiadrenergics.
4. Drug acting on central and
peripheral nervous system.
• It is classified into:
1)Skeletal muscle relaxants.
2)Local Anesthetics.
3)General Anesthetics.
4)Drug used in Pre-anaesthetic medication.
5)Sedatives & Hypnotics.
6)Anti-epileptic Drugs
7)Anti-parkinsonian Drugs.
8)Anti-psychotic Drugs.
9)Anti-anxiety Drugs.
10)Anti-depressants.
11)Anti-manic [mood stabilising ] Drugs.
16. Adrenergic Drugs [Sympathomimetics]
• It is classified into :
1.Based on biochemical basis.
a). Catacholamines.
I. Natural : Adrenaline, Noradrenaline, Dopamine.
II.Synthetic: Isoprenaline, Dobutamine.
b) Non catacholamines- Ephedrine, Amphetamine,
Mephentermine, phenylephrine.
17. Based on Mechanism of action
a) Directly acting – Adrenaline, Noradrenaline,
Isoprenaline, phenylephrine, salbutamol,
Methoxamine, Xylometazoline.
b) Indirectly acting – Tyramine.
c) Acting by both Mechanisms - Ephedrine,
Amphetamine, Mephentermine.
18. 3. Based on spectrum activity
a) α antagonists [Alpha]
I. α 1 selective- phenylephrine.
II. α 2 selective – clonidine [catapres]
b) β antagonist [Beta]
I. Non selective – Isoprenaline
II. β1 selective Dobutamine.
III.β2 selective – Terbutaline, Salbutamol.
c)α antagonists & β antagonist -Adrenaline,
Noradrenaline.
d)Dopamine agonists- Dopamine [D1& D2]
Fenoldopam [D1]
25. Centrally Acting muscle relaxants
a) Central α2 agonist – Tizanidine.
b) Mephenesin group – Mephenesin,
Carisoprodol, Methocarabamol,
Chlorozoxazone, Chloromezanone.
c) GABA derivatives: Baclofen.
d) Benzodiazepines: Diazepam and others.
34. Sedatives & Hypnotics
1. Barbiturates:
a) Ultra short acting: Thiopentone,
Methohexitone, Hexobarbitone.
b) Short acting: Secobabitone, Butobarbitone,
Pentobarbitone.
c) Long acting: Phenobarbitone,
Mephobarbitone.
50. References
1. Govind S. Mittal, Pharmacology at a Glance – Classification of
Drugs and Drug of Choice, Paras medical publication books, 4th
Edition 2016, Pg no. 01 – 12
2. Dr. P.K. Panwar, Essentials of pharmacology for nurses, AITBS
pub. 2017, India, Pg no. 90 – 117.
3. Dr. Suresh k sharma, Textbook of pharmacology, pathology &
genetics for nurses, Jaypee pub. 2016 India Pg no 256 – 360.
4. Tara v. Shanbhag, Smita shenoy, Pharmacology preparation
manual for undergraduate, Elsevier pub. 2014. Pg no. 164 – 233.
5. Marilyn Herbert – Ashton, Nancy Clarkson, Pharmacology,
Jones & Barllet pub 2010 India, Pg no 101 – 180.
6. Govind s. mittal, Pharmacology at a glance, Paras medical book
pub. 2009 India 1 – 12.
7. Madhuri Inamdar, Pharmacology in nursing, Vora medical pub.
2006 India 1st
edition, Pg no 120 – 152.