1) The document discusses various normal anatomical structures and imaging artifacts that can be mistaken for abnormalities in MRI of the wrist and elbow joints.
2) Specific examples mentioned include "pseudoerosions" of wrist bones that are actually intraosseous blood vessels, as well as pseudodefects of the capitellum and trochlear bones of the elbow that appear as interruptions of the cortical bone.
3) The document emphasizes that these pseudodefects should not be confused with osteochondral lesions, as they do not exhibit marrow edema and occur in different locations. It provides images to illustrate examples of these normal variants.
Appendicular trauma refers to injuries or damage sustained to the appendicular skeleton, which includes the bones of the upper and lower extremities (arms and legs) as well as the pelvis. These injuries can result from various causes such as accidents, falls, sports-related incidents, or direct blows.
Appendicular trauma refers to injuries or damage sustained to the appendicular skeleton, which includes the bones of the upper and lower extremities (arms and legs) as well as the pelvis. These injuries can result from various causes such as accidents, falls, sports-related incidents, or direct blows.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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Presentation1, artifacts and pitfalls of the wrist and elbow joints.
1. Dr/ ABD ALLAH NAZEER. MD.
Artifacts and Pitfalls of the Wrist and Elbow Joints.
2.
3.
4.
5.
6.
7. In 13% of examined wrist we noted
"pseudoerosion". All cases
intraosseous blood vessels
nutritional canals were visible in all
individuals, most commonly in
capitate and lunate bones. We
present possible diagnostic pitfalls in
MR images of Rheumatoid patients.
8. Sagittal, Coronal and Axial T1 Turbo 3D magnetic resonance
image demonstrates "pseudoerosion" of the capitate bone.
9. Sagittal and Axial T1 Turbo 3D
magnetic resonance image
demonstrates "pseudoerosion"
of the lunar bone.
10. Wraparound artifact. MR image of the wrist shows wraparound artifact, with
structures from outside the FOV mapped into the image. The phase-encoding
direction is parallel to the long axis of the hand and wrist; the more proximal
and distal cross sections are mapped into the section of interest.
14. Triangular ligament. (a) Coronal 2D GRE T2*-weighted MR image (1.5-mm section thickness, 50-mm FOV, 224 × 512
matrix with ZIP) shows the triangular ligament. The proximal lamina of the ligament attaches to the fovea of the
ulnar styloid process (dashed arrow). The distal lamina attaches to the tip of the ulnar styloid process (solid arrow)
(12-14). The region of increased signal intensity between the laminae is the ligamentum subcruentum (arrowhead).
not tear (b) Corresponding low-power photomicrograph (azan stain) shows collagen fibers with vascular connective
tissue (arrows). Demineralized bone appears dark red, hyaline cartilage appears medium blue, and collagen fibers
with vascular connective tissue appear as heterogeneous regions of mixed light blue and white.
15. Elbow
Although is not an articulation often evaluated by MRI, such as shoulder
and knee, the elbow can present pitfalls and is essential that radiologists
be aware to not make mistakes.
Pseudodefect of the capitellum
Pseudodefect of the capitellum is one of the most frequently pitfall found
in elbow, usually seen in coronal and sagittal images, and should not be
confused with osteochondral lesion.
Two osteochondral diseases are described in capitellum: osteochondritis
dissecans and Panner's disease.
Panner's disease generally affects younger patients, around 5-10 years,
and tends to involve the whole capitellum. Osteochondritis dissecans
occurs in patients in adolescence, involvement of the capitellum is often
partial and tends to form loose bodies.
However, the osteochondral lesion occurs on the anterior aspect of the
capitellum while pseudo-defect affects the posterolateral aspect and there
is no marrow edema. The presence of synovial fluid or contrast makes
easier to recognize this pseudodefect.
16. Trochlear pseudodefect
Trochlear pseudodefect is a bare area devoid of cartilage localized in the trochlear
notch. It is usually has a small size, measuring up to 7 mm in width.
The lesion appears as a slight interruption of cortical bone in sagittal images and
like the pseudo-defect of the capitellum should not be confused with
osteochondral injury. The absence of edema confirms it is a normal find.
It is important to report that trochlear pseudodefect can be a place for loose
bodies’ deposit.
Transverse trochlear ridge:
Transverse trochlear ridge is detected as central elevation in the trochlear groove
on sagittal images and was detected by Rosenberg and colleagues in 68% of the
ulnar bones inspected.
It is usually very small, up to 3 mm high, but in a few case can be prominent and
simulate an osteophyte.
Triceps tendon: striations and insertion
The triceps tendon is formed by a small surface layer and another layer deeper
and thicker, which combine to insert on the posterior aspect of the olecranon.
At the triceps tendon insertion high signal can be detected and should not be
confused with tear or degeneration. This high signal occurs by the presence of
fibro-fatty tissue between the tendon fibers.
17. Sagittal and coronal proton-density fast spin-echo (TR 2300 ms, TE 35
ms) demonstrate the pseudodefect of the capitellum (white arrows).
18. (c) Coronal and (d) sagittal T2-weighted images of the elbow in a 53-year-old
woman with lateral epicondylosis. Images demonstrate subcortical cystic
change (arrow) along the posterior portion of the capitellum, compatible
with a pseudodefect, not to be mistaken for an osteochondral lesion.
22. Plica: This structure on the lateral side of the joint is sometimes seen and is a plica.
It can be prominent and almost look like a meniscus. It is a normal structure, but
sometimes it is thickened or irregular and it may be a cause of symptoms.
24. Sagittal proton-density fast spin-echo (TR 2300 ms, TE 35 ms) image of the elbow showing
cortical interruption (white arrow): trochlear pseudodefect. There is no marrow edema.