This document provides a 5-step guide to safely managing peroxide-forming chemicals in laboratories. Step 1 explains that peroxide formers are chemicals that can spontaneously form explosive peroxide compounds over time when exposed to factors like oxygen, light, or heat. Step 2 outlines protocols for proper storage, handling, and testing of peroxide formers. Step 3 recommends training researchers on identification and safety procedures for peroxide formers. Step 4 discusses determining appropriate disposal times based on chemical hazard classifications. Step 5 suggests developing long-term plans for continual education and chemical inventory management. The document aims to help laboratories avoid accidents from improperly managed peroxide-forming chemicals.
Chemical safety at laboratories & Chemical industriesNikesh Banwade
Presentation on Chemical Safety at Laboratory and Chemical Industries.The PPT includes
OHSA’s Haz-Com Standard, Chemical Labels and Identification, Chemical Procurement, Chemical Storage, Chemical Transporting and Emergency Response Procedure.
Chemical safety at laboratories & Chemical industriesNikesh Banwade
Presentation on Chemical Safety at Laboratory and Chemical Industries.The PPT includes
OHSA’s Haz-Com Standard, Chemical Labels and Identification, Chemical Procurement, Chemical Storage, Chemical Transporting and Emergency Response Procedure.
A presentation about NFPA diamonds and MSDSs. Highly modified off of one I found on the internet here -- http://www.nisd.net/communicationsarts/pages/chem/ppt/safety_pres.ppt
The health effects of hazardous chemicals are often less clear than the physical hazards. Data on the health effects of chemical exposure, especially from chronic exposure, are often incomplete. When discussing the health effects of chemicals, two terms are often used interchangeably - toxicity and hazard.
Safe Chemical Handling & Initial Spill ResponseDavid Horowitz
This presentation was prepared for the Sixteenth Annual Southeastern Massachusetts Drinking Water Fair held on June 16, 2011 at the Massachusetts Maritime Academy. The event was hosted by the Barnstable County Water Utilities Association and the Plymouth County Water Works Association. Attendees received Training Contact Hours (TCHs).
Chemical Management System in Textile Manufacturing and Processing is required to achieve the safe use of chemicals and to control the hazards that they present to workers, the community and the environment. It can take a lot of chemicals to make clothes. The apparel sector certainly is not as chemical intensive as other global industries, but its variety of chemical operations and materials does present a range of potential hazards to its workers and the surrounding communities and environment.
Chemicals are the most common and significant health hazards and Chemicals can be hazardous for numerous reasons and can combine with other chemicals to make new hazards.
Therefore All hazards must be taken into account when using and storing chemicals.
# Understand that chemicals hazards.
# Understand that safe storage is an important issue.
# Understand that many chemical injuries result from
improper storage.
# Know four basic rules of chemical safety.
# Be aware of the categories of dangerous chemicals
and appropriate safety precautions.
COSHH (Control of Substances Hazardous to Health) TrainingTraining Express
COSHH covers chemicals, fumes, dust, vapours, mists and gases, as well as any packaging with hazard symbols. This COSHH – Control of Substances Hazardous to Health Training Course provides training for employees of all levels, teaching them how to comply with COSHH safety regulations and recognize any potential hazards and risks while at work.
See Details: http://bit.ly/2Wx0N0z
A presentation about NFPA diamonds and MSDSs. Highly modified off of one I found on the internet here -- http://www.nisd.net/communicationsarts/pages/chem/ppt/safety_pres.ppt
The health effects of hazardous chemicals are often less clear than the physical hazards. Data on the health effects of chemical exposure, especially from chronic exposure, are often incomplete. When discussing the health effects of chemicals, two terms are often used interchangeably - toxicity and hazard.
Safe Chemical Handling & Initial Spill ResponseDavid Horowitz
This presentation was prepared for the Sixteenth Annual Southeastern Massachusetts Drinking Water Fair held on June 16, 2011 at the Massachusetts Maritime Academy. The event was hosted by the Barnstable County Water Utilities Association and the Plymouth County Water Works Association. Attendees received Training Contact Hours (TCHs).
Chemical Management System in Textile Manufacturing and Processing is required to achieve the safe use of chemicals and to control the hazards that they present to workers, the community and the environment. It can take a lot of chemicals to make clothes. The apparel sector certainly is not as chemical intensive as other global industries, but its variety of chemical operations and materials does present a range of potential hazards to its workers and the surrounding communities and environment.
Chemicals are the most common and significant health hazards and Chemicals can be hazardous for numerous reasons and can combine with other chemicals to make new hazards.
Therefore All hazards must be taken into account when using and storing chemicals.
# Understand that chemicals hazards.
# Understand that safe storage is an important issue.
# Understand that many chemical injuries result from
improper storage.
# Know four basic rules of chemical safety.
# Be aware of the categories of dangerous chemicals
and appropriate safety precautions.
COSHH (Control of Substances Hazardous to Health) TrainingTraining Express
COSHH covers chemicals, fumes, dust, vapours, mists and gases, as well as any packaging with hazard symbols. This COSHH – Control of Substances Hazardous to Health Training Course provides training for employees of all levels, teaching them how to comply with COSHH safety regulations and recognize any potential hazards and risks while at work.
See Details: http://bit.ly/2Wx0N0z
Removal of peroxide from thf mfg of thf using activated alumina ballsPharma Desiccants
Chemical compounds when stored for a prolonged period and later when exposed to air and light undergo slow oxidation and lead to the formation of Peroxide, which can be visualized in the form of Crystals. The Peroxide thus, formed get detonated on combining with other compounds or when disturbed due to fiction or heat resulting in an explosion
alo
Working in a laboratory usually involves working with various chemical, physical, and biological hazards. Because the hazards vary from laboratory to laboratory, employers must address the hazards specific to their laboratories. Standard precautions are meant to reduce the risk of transmission of blood borne and other pathogens from both recognized and unrecognized sources. They are the basic level of infection control precautions which are to be used, as a minimum, in the health care settings.
For many years, a class of non-bleach liquid sporicidal disinfectants, also known as cold sterilants, have been used in biological research and pharmaceutical production to control microbial contamination. These are made up of a stabilized mixture of peracetic acid (PAA), hydrogen peroxide and acetic acid. Spor-Klenz®, manufactured by STERIS Life Sciences, is a popular example. Sampling and analysis of PAA is a challenge because it coexists with acetic acid and hydrogen peroxide and PAA’s chemical properties are similar to the two chemicals. Although ACGIH has established a TLV® for PAA, neither NIOSH nor OSHA have a sampling or analytical method for it. Additionally, PAA and acetic acid have STELs which require short-term monitoring.
Chemical Safety Guidelines with hazard and risk controlsDecentN
This course briefly covers chemical hazard and risk associated with appropriate safety controls. This presentation also cover chemical labeling and classification as per GHS system.
How to Prepare for and Respond to a Confirmed COVID-19 Case at Your Lab or Ma...Triumvirate Environmental
As essential businesses continue to operate, it’s crucial to consider how to handle a confirmed COVID-19 case in the workplace. Despite safety precautions to avoid the spread, one of your employees may get sick – do you know what to do? The COVID-19 pandemic has drastically altered how we work and operate. Take a proactive approach to safely keep your business operational in the event of a confirmed COVID-19 case by developing sound disinfection policies and procedures.
ISO auditing leads to improved company EHS culture, consistency, and team focus. When organizations conform to these ISO standards and obtain third-party ISO certification, it authenticates that they utilize standardized management systems to continuously improve Occupational Health and Safety and Environmental performance.
Does your organization need an industrial hygiene program? Are you looking to create a program but don’t know where to start? Industrial hygiene allows you to anticipate, evaluate and control environmental factors that impact people’s health. Critical to environmental health and safety, an industrial hygiene program is important not only for regulatory compliance but also to maintain your public relations and reputation.
The deadlines for Tier II Reports, Biennial Reports, and OSHA 300 Logs are all fast approaching. Are you prepared to file all your necessary reports in time? It is important to take the time to carefully review your facility to determine your requirements for these regulatory reports.
Cannabis growers, cultivators, and distributors face unique compliance challenges when navigating federal and state regulations, managing hazardous and non-hazardous waste streams, and ensuring your facility runs safely and compliantly. This webinar will help early-stage and fast-growing cannabis companies understand the state and federal regulatory environment, obtain permits and licenses, and build environmental, health, and safety (EH&S) programs. Whether your cannabis organization is new to the compliance world or has some safety programs in place, this webinar will provide guidance on how to reach operational excellence.
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OSHA violations are expensive and time consuming to resolve. It is significantly cheaper and easier to create an OSHA-compliant workplace from the start. Ensuring OSHA compliance requires a complete understanding of the OSHA requirements and a complete assessment of your current workplace. In this webinar, our expert will walk you through the key steps to creating an OSHA-compliant workplace.
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2019 Healthcare Accreditation Regulatory Updates: How Do the New Regulations ...Triumvirate Environmental
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Oil spills present real public health and environmental concerns. In response to these concerns, the EPA created rules around SPCC. The EPA’s SPCC rules are meant to prevent oil discharge from entering navigable waters and/or adjoining shorelines.
There have been many recent changes to the DEA and EPA regulations regarding pharmaceutical waste management. Is your organization compliant with the current rules? Here is a comprehensive look at the disposal and onsite waste management regulations for controlled substances.
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There are over 90 biotechnology and pharmaceutical laboratories located within the Cambridge city limits. With such a high concentration of labs, the city has stringent regulations to contain exposure risks and ensure that the community is safe. In this session, the Department of Public Health will discuss lab safety in the city. Join us to gain a more comprehensive understanding of Massachusetts and Cambridge regulations to ensure you are running a safe and compliant lab.
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Medical or Biological Waste, a.k.a., Regulated Medical Waste, is regulated by the Massachusetts Department of Public Health. DPH has adopted management requirements codified under 105 CMR 480 that affect those who generate such wastes. Individuals impacted by these rules would be employees who are responsible for the medical/bio waste management program and those who manage the waste onsite (e.g., internal transport, storage, onsite treatment, and other handling).
Recently the National Safety Council collaborated with three Campbell Institute members to understand the role fatigue plays in their operations at selected locations. Research participants took part in a two-part survey consisting of an operational needs assessment and an employee survey.
Does your organization run internal audits regularly? Prepare for a regulator to come knocking at your door by catching areas of non-compliance before the inspector can. Internal audits allow you to identify gaps in your existing EHS programs and improve processes before an official inspection, so you can be confident in your audit-readiness.
Despite well-defined requirements, procedures, and targets, many organizations still struggle with delivering well-defined, exceptional EHS compliance programs. A strong external partnership can reposition your EHS compliance program and drive strong operational and financial outcomes. But once you decide to establish an EHS partnership, how do you ensure you are getting the most out of it?
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Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Toxic effects of heavy metals : Lead and Arsenicsanjana502982
Heavy metals are naturally occuring metallic chemical elements that have relatively high density, and are toxic at even low concentrations. All toxic metals are termed as heavy metals irrespective of their atomic mass and density, eg. arsenic, lead, mercury, cadmium, thallium, chromium, etc.
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As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Salas, V. (2024) "John of St. Thomas (Poinsot) on the Science of Sacred Theol...Studia Poinsotiana
I Introduction
II Subalternation and Theology
III Theology and Dogmatic Declarations
IV The Mixed Principles of Theology
V Virtual Revelation: The Unity of Theology
VI Theology as a Natural Science
VII Theology’s Certitude
VIII Conclusion
Notes
Bibliography
All the contents are fully attributable to the author, Doctor Victor Salas. Should you wish to get this text republished, get in touch with the author or the editorial committee of the Studia Poinsotiana. Insofar as possible, we will be happy to broker your contact.
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imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
BLOOD AND BLOOD COMPONENT- introduction to blood physiology
5 Steps to Managing Peroxide-Forming Chemical
1. 5 Steps to Managing
Peroxide-Forming
Chemicals
Keep your
chemicals from
blowing up in
your face
(literally)
2. About the Experts
Olivia
Smith
Olivia
Smith
is
a
Program
Manager
at
Triumvirate
Environmental.
In
this
role
she
manages
a
pharmaceu:cal
company’s
chemical
and
biological
waste
programs
as
well
as
their
inventory
program.
Olivia
leads
a
team
of
four
who
are
responsible
for
comple:ng
safety
and
compliance
inspec:ons
in
labs
and
workspaces.
She
graduated
from
Goucher
College
with
a
BA
in
Biology.
Schuyler
Stuart
Schuyler
Stuart
has
worked
at
Triumvirate
Environmental
for
4
years.
He
is
currently
working
as
a
Life
Sciences
opera:ons
manager
working
to
manage
opera:ons
as
well
as
Life
Sciences
biotech
and
pharmaceu:cal
clients.
He
manages
of
team
of
environmental
specialists
at
these
sites.
He
graduated
from
Hartwick
College
with
a
BA
in
Biology.
5 Steps to Managing Peroxide Forming Chemicals 2
3. Introduction
A
student
at
University
of
California,
Berkeley
was
injured
in
a
peroxide-‐forming
chemical
explosion
in
November
of
2006.
Glass
fragments
shot
into
her
face
and
torso.
She
needed
s:tches
above
her
eyes
as
well
as
other
hospital
treatments.
Peroxide
forma5on
in
laboratory
chemicals
by
auto-‐oxida5on
can
result
in
unexpected
lab
explosions,
resul5ng
in
injuries
and
even
fatali5es.
This
guide
will
teach
you
to
protect
your
laboratory
workers
from
accidents
like
this
in
5
steps.
Let’s
get
started!
5 Steps to Managing Peroxide Forming Chemicals 3
4. 5 Steps
1 What Are Peroxide Formers?
2 Protocol: The Dos & the Don’ts
3 Train in Playing it Safe
4 Know When to Discard
5 Plan for the Long Haul
5 Steps to Managing Peroxide Forming Chemicals 4
5. 1 What Are Peroxide Formers?
What
are
they?
In
short,
peroxide
formers
are
chemicals
that
if
leU
aUer
opening
for
a
certain
amount
of
:me
or
if
treated
in
a
certain
way,
can
form
poten:ally
explosive
peroxide
by-‐products.
The
list
of
peroxide
forming
chemicals
is
long
and
broken
up
into
four
classes
(A
through
D).
Class
A
peroxide
formers
are
the
most
likely
to
form
peroxide
crystals
and
should
be
disposed
of
aUer
three
months.
Class
D
chemicals
are
the
least
likely
and
should
be
disposed
of
aUer
12
months.
Stay
tuned
for
more
details
on
these
classes
in
following
chapters.
5 Steps to Managing Peroxide Forming Chemicals 5
6. 1 What Are Peroxide Formers?
What
are
they?
(Con5nued)
It’s
important
to
audit
your
chemical
supply
thoroughly
before
determining
whether
or
not
you’re
using
peroxide
forming
chemicals.
How
do
they
form?
Chemicals
can
form
dangerous
peroxide
by-‐products
in
a
number
of
ways.
The
most
dangerous
chemicals
are
those
that
become
poten:ally
explosive
when
stored
for
a
certain
amount
of
5me
–
usually
aGer
3-‐months
of
opening.
Isopropyl
ether
and
vinylidene
chloride
are
examples
of
such
chemicals.
5 Steps to Managing Peroxide Forming Chemicals 6
7. 1 What Are Peroxide Formers?
How
do
they
form?
(Con5nued)
Peroxides
can
form
when
boZles
containing
these
chemicals
are
exposed
to
light,
heat,
oxygen,
moisture,
or
impuri:es.
When
they
have
formed,
unscrewing
a
cap
can
contribute
to
a
peroxide
explosion.
Small
things
like
air
exposure
can
contribute
to
crystals
forming
and
explosion
upon
opening.
The
explosion
this
could
cause
could
break
a
boZle
into
pieces
in
a
millisecond
and
send
shards
flying
with
enough
force
to
fatally
injure
a
researcher.
5 Steps to Managing Peroxide Forming Chemicals 7
8. 1 What Are Peroxide Formers?
How
do
they
form?
(Con5nued)
Other
chemicals
can
become
explosive
if
they
become
concentrated
through
processes
such
as
dis5lla5on
or
evapora5on
during
laboratory
research.
Some
of
these
chemicals
are
diethyl
ether,
tetrahydrofuran,
1,
4
dioxane,
isopropyl
ether,
cyclohexene,
glycol
ethers,
decalin,
and
2-‐propanol.
Here
is
a
list
of
common
peroxide
forming
chemicals.
This
list
is
not
complete.
To
determine
if
you
have
any
peroxide
chemicals
in
your
workspace
contact
one
of
our
specialists
for
a
consulta:on.
5 Steps to Managing Peroxide Forming Chemicals 8
9. 1 What Are Peroxide Formers?
How
do
I
know
if
they’re
dangerous?
So,
if
you’ve
determined
you
have
peroxide
forming
chemicals,
how
do
you
know
when
peroxides
have
formed
in
your
solvents?
Although
tes:ng
is
the
best
way
to
determine
this,
there
are
telltale
signs
–
visible
crystals
that
look
like
snowflakes,
precipitate,
discolora5on
of
solids,
and/or
an
oily
viscous
layer.
If
any
of
these
warning
signs
are
present,
researchers
should
cease
moving
forward
in
any
usage
of
this
solvent
and
enlist
the
help
of
EH&S.
Even
if
there
aren’t
any
telltale
signs
of
peroxide,
all
people
handling
formers
should
have
explicit
requirements
for
safe
handling.
In
the
next
sec:on
you’ll
learn
what
these
requirements
should
be.
5 Steps to Managing Peroxide Forming Chemicals 9
10. 5 Steps
1 What Are Peroxide Formers?
2 Protocol: The Dos & the Don’ts
3 Train in Playing it Safe
4 Disposal Determinations
5 Plan for the Long Haul
5 Steps to Managing Peroxide Forming Chemicals 10
11. 2 Protocol: The Dos & the Don’ts
Your
EH&S
department
should
develop
a
list
of
management
protocols
for
researchers.
While
protocol
should
be
tailored
to
your
specific
environment,
we
did
most
of
the
heavy
liUing
and
a
made
a
list
of
Dos
and
Don’ts
that
should
be
included
in
all
protocols.
Do’s
1. Avoid
less
stable
chemicals
if
the
procedure
can
do
without
them.
2. If
a
peroxide-‐forming
solvent
is
necessary
to
use,
es:mate
in
advance
–
as
accurately
as
possible
–
the
amount
needed
for
a
certain
procedure.
This
will
help
you
avoid
the
costly
disposal
of
leUovers.
3. Use
any
old
boZles
(with
date
of
receipt
under
1
year)
before
ordering
or
using
new
ones.
4. Purchase
chemicals
with
inhibitors
such
as
butylated
hydroxytoluene
5 Steps to Managing Peroxide Forming Chemicals 11
12. 2 Protocol: The Dos & the Don’ts
Do’s
(Con5nued)
5. Store
peroxide-‐forming
solvents
in
opaque
containers
under
inert
atmospheric
gases.
6. Keep
away
from
heat
and
light.
7. Close
containers
:ghtly
and
keep
caps
free
from
dirt,
dust,
powders,
and
other
liquids.
8. Open
boZles
with
these
chemicals
carefully
behind
a
safety
shield
in
a
fume
cupboard.
9. Test
for
peroxide
forma:on
before
conduc:ng
dis:lla:on
or
evapora:on
with
pre-‐used
solvents.
Use
test
strips,
interferences,
and
potassium
iodide.
>80
ppm
peroxides
should
be
disposed
of!
If
lower,
keep
retes:ng
every
3
months.
Chemical
distributors
will
provide
inhibitor
formula:ons
and
storage
:mes
for
products.
10. If
boZles
display
and
peroxide
warning
signs
(like
visible
crystals
or
precipita:on)
contact
EH&S
professionals
to
dispose
of
the
chemical
immediately.
5 Steps to Managing Peroxide Forming Chemicals 12
13. 2 Protocol: The Dos & the Don’ts
Don’ts
1. Do
not
perform
dis:lla:on
or
evapora:on
prior
5 Steps to Managing Peroxide Forming Chemicals 13
to
tes:ng.
2. Do
not
dis:ll
peroxide-‐forming
solvents
at
all
unless
this
process
is
very
well
controlled.
3. Do
not
return
unused
chemical
to
the
container.
Dispose
of
it
appropriately.
4. Do
not
touch
a
boZle
that
contains
a
peroxide-‐
forming
solvent
if
you
see
snowflake-‐like
crystals,
any
precipitate,
discolored
solids,
or
a
viscous
layer.
Contact
EH&S.
5. Do
not
expose
peroxide-‐forming
solvents
to
heat,
light,
air,
moisture,
or
impuri:es.
6. Do
not
use
a
boZle
of
peroxide-‐forming
solvent
without
first
reading
the
date
on
the
label.
14. 2 Protocol: The Dos & the Don’ts
For
a
good
example
of
a
protocol
sheet,
look
here.
We
suggest
typing
up
instruc:ons
in
addi:on
to
this
list
above
and
hanging
it
up
throughout
the
facility
to
educate
employees
and
ensure
compliance.
5 Steps to Managing Peroxide Forming Chemicals 14
15. 5 Steps
1 What Are Peroxide Formers?
2 Protocol: The Dos & the Don’ts
3 Train in Playing it Safe
4 Know When to Discard
5 Plan for the Long Haul
5 Steps to Managing Peroxide Forming Chemicals 15
16. 3 Train in Playing it Safe
There
are
several
simple
steps
you
can
take
to
ensure
your
researchers
are
fully
educated
on
proper
peroxide
former
protocol.
To
make
this
easier
on
you,
we’ve
created
a
checklist.
Employee
Educa5on
Checklist
q Require
formalized
training
for
new
researchers.
q Supply
handbooks
and
addi:onal
lab
safety
and
chemical
management
reading
to
all
researchers.
q Con:nue
to
mandate
regular
refreshers
for
undergraduate
and
graduate
researchers
aUer
their
first
year.
q Review
your
inventory
and
make
a
list
of
materials
that
can
poten5ally
form
peroxides.
Make
this
list
and
the
characteris:cs/hazard
levels
of
each
chemical
public
to
your
researchers.
You
can
find
an
example
here,
from
a
higher
educa:on
ins:tute
with
over
7,000
students.
Note
that
this
list
is
a
part
of
a
safety
topic
update
sent
out
from
EH&S.
5 Steps to Managing Peroxide Forming Chemicals 16
17. 3 Train in Playing it Safe
Employee
Educa5on
Checklist
(Con5nued)
q Implement
chemical
safety
by
gelng
word
out
to
researchers
in
a
way
that
catches
their
aZen:on.
Include
a
list
of
chemicals
&
hazards
in
prominent
parts
of
the
lab,
warning
labels
on
boZles
that
contain
peroxide-‐forming
solvents,
and
handling
:ps
in
standard
of
procedure
(SOP)
documenta:on,
trainings,
email
updates,
etc.
q Require
researchers
to
read
Safety
Data
Sheets
(SDSs)
prior
to
working
with
any
new
chemical.
5 Steps to Managing Peroxide Forming Chemicals 17
18. 5 Steps
1 What Are Peroxide Formers?
2 Protocol: The Dos & the Don’ts
3 Train in Playing it Safe
4 Know When to Discard
5 Plan for the Long Haul
5 Steps to Managing Peroxide Forming Chemicals 18
19. 4 Know When to Discard
Removing
expired
peroxide-‐forming
solvents
should
be
a
process
managed
by
EH&S
and
par:cipated
in,
to
an
extent,
by
researchers.
While
researchers
should
track
dates
of
receipt
and
last-‐opened
on
boZles
in
the
lab
and
test
for
peroxides,
it
is
up
to
EH&S
to
develop
and
implement
the
label
system,
as
well
as
to
monitor
that
researchers
are
fulfilling
this
label
system,
and
to
perform
regular
inventory
inspec:ons.
Below
is
an
example
of
a
label.
The
University
of
Illinois
uses
this
for
peroxide-‐forming
chemicals.
5 Steps to Managing Peroxide Forming Chemicals 19
20. 4 Know When to Discard
(con:nued)
An
even
more-‐detailed
example
can
be
found
below.
This
label,
taken
from
a
higher
educa:on
ins:tu:on,
contains
a
hazard
warning,
direc:ons
for
handling,
EH&S
contact
informa:on,
date
received
and
opened,
disposal
instruc:ons,
and
tes:ng
dates/
results.
5 Steps to Managing Peroxide Forming Chemicals 20
21. 4 Know When to Discard
(con:nued)
In
order
to
determine
disposal
requirements,
divide
your
chemical
inventory
into
the
four
different
classes
of
peroxide-‐
forming
chemicals:
By
labeling
tracking
and
repor:ng
all
chemicals
you
can
ensure
safety
and
compliance
for
your
organiza:ons
and
it’s
employees.
5 Steps to Managing Peroxide Forming Chemicals 21
22. 4 Know When to Discard
(Con:nued)
While
researchers
should
be
aware
of
these
disposal
requirements
and
no:fy
EH&S
of
disposal
needs,
it
is
EH&S’s
responsibility
to
ensure
that
these
standards
are
being
followed.
Disposing
of
chemicals
prior
to
peroxide
forma:on
saves
your
research
ins:tu:on
thousands
of
dollars.
Costs
depend
on
the
amount
of
material,
but
typically
are
between
$2,000
and
$6,000.
Wai:ng
to
dispose
of
a
chemical
un:l
peroxides
form
may
also
require
your
ins:tu:on
to
pay
a
fine
to
your
local
fire
or
police
departments.
Not
only
are
disposal
costs
high
for
chemicals
peroxides,
but
the
NFPA
has
strict
guidelines
for
storage
limits
of
these
materials.
Your
fire
department
could
charge
anywhere
from
$100
to
$1000
or
shut
down
your
lab
and
building
if
expired
peroxides
are
found.
If
negligence
is
found,
OSHA
could
also
charge
tens
of
thousands
of
dollars.
5 Steps to Managing Peroxide Forming Chemicals 22
23. 4 Know When to Discard
What
can
you
do
today?
Perform
an
inventory
check
to
benchmark
the
current
standing
of
chemicals
within
your
labs.
If
you
have
boZles
with
unknown
cons:tuents
in
your
lab,
or
if
the
date
of
origin/last-‐open
of
a
boZle
containing
peroxide-‐forming
chemicals
is
found
within
your
building,
cease
research
immediately
and
ask
the
researcher
who
owns
the
boZle
for
further
details.
If
the
cons:tuents
of
a
boZle
with
peroxide
indicators
remain
unknown,
or
the
dates
for
peroxide-‐forming
chemicals
cannot
be
determined,
bring
in
an
outside
company
with
high-‐haz
experience
to
deal
with
this
situa:on.
5 Steps to Managing Peroxide Forming Chemicals 23
24. 5 Steps
1 What Are Peroxide Formers?
2 Protocol: The Dos & the Don’ts
3 Train in Playing it Safe
4 Know When to Discard
5 Plan for the Long Haul
5 Steps to Managing Peroxide Forming Chemicals 24
25. 5 Plan for the Long Haul
4
Keys
to
Long-‐term
Success
1. Regular
inspec5ons
–
the
University
of
California
performs
safety
inspec:ons
of
lab
space
every
two
weeks,
verifying
that
all
containers
are
labeled
and
properly
sealed.
You
should
also
have
someone
in
EH&S
monitor
and
replenish
boZle
labels
and
test
materials
so
that
researchers
have
no
excuse
when
it
comes
to
following
protocol.
2. Con5nual
training
–
who
tracks
training
in
your
EH&S
department?
Are
researchers
being
no:fied
and
held
accountable
when
they
need
to
refresh
their
training?
3. Applicability
–
Share
with
researchers
instances
of
mismanagement.
In
order
to
make
peroxide
hazards
real
to
your
researchers,
send
out
incident
reports
at
your
ins:tu:on,
and
distribute
news
ar:cles
that
show
the
unfortunate
aUer-‐effects
of
improper
handling.
4. Accountability
–
Do
researchers
know
the
consequences
of
not
s:cking
to
EH&S
rules?
How
are
they
held
accountable
if
they
do
not
properly
label,
manage,
and
dispose
of
peroxide-‐
forming
chemicals?
5 Steps to Managing Peroxide Forming Chemicals 25
26. cOnclusion
The
dangers
of
peroxides
are
real,
but
they
should
not
prevent
staff
in
your
labs
from
performing
what
they
are
there
for
–
research.
EH&S
departments
should
use
this
guide
to
develop
a
plan
for
the
management
of
peroxide-‐forming
chemicals,
to
improve
a
current
plan,
or
to
educate
researchers.
Increased
awareness
in
labs
triggers
compliant
behaviors
and
minimizes
risk
and
cost.
Special
thanks
to
New
England
Quality
Manager,
Ted
Dubiel
whose
wri=ng
was
an
invaluable
resource
in
the
crea=on
of
this
guide.
5 Steps to Managing Peroxide Forming Chemicals 26
27. about
Triumvirate
Environmental
is
a
environmental
services
provider
to
life
sciences,
biotechnology,
and
pharmaceu:cal
companies
throughout
the
US.
We
pride
ourselves
on
providing
innova:ve,
customer-‐in:mate
environmental
services
that
keep
your
organiza:on
safe,
compliant,
and
focused
on
its
mission.
To
learn
more
about
peroxides
management
,
or
any
of
our
life
science
services,
please
call:
888-‐TEI-‐WOWS
5 Steps to Managing Peroxide Forming Chemicals 27
28. Complete Peroxide Former
Management
5 Steps to Managing Peroxide Forming Chemicals 28
We
will:
• Do
a
complete
chemical
audit
of
your
en:re
inventory
• Label
all
peroxide
forming
compounds
with
a
“peroxide
former”
tag
• Label
everything
with
received
and
expira:on
dates
• Train
employees
on
peroxide
formers
&
encourage
addi:onal
labeling
to
beZer
determine
peroxide
poten:al
• Perform
regular
sweeps
of
storage
area.
• Proac:vely
move
and
material
due
to
expire.
• Remove
any
dangerous
peroxide
formers
safely
and
compliantly
Call for a
Consultation