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Organozinc compounds
1) Organozinc compounds are less reactive than organolithium and organomagnesium compounds due to their more covalent C-Zn bond, allowing preparation of functionalized derivatives.
2) Organozinc compounds are commonly prepared by reacting primary or secondary halides with zinc metal or Rieke zinc under inert atmosphere due to their sensitivity to oxidation.
3) Organozinc reagents are useful in organic syntheses such as Reformatsky reactions, Simmons-Smith cyclopropanation reactions, and cross-coupling reactions like Negishi and Fukuyama couplings.
Organolithium Compounds and Reactions
This PPT is usefull for aspirants of JEE-IIT, CSIR-NET and UPSC exams in CHEMISTRY section. It is also usefull for grduates and Post graduates students of Indian Universities.
organomagnesium-compounds.ppt
The document discusses organomagnesium halides (Grignard reagents). It describes how Grignard reagents are useful synthetic intermediates for carbon-carbon bond formation and are sources of nucleophilic carbanions. It summarizes several reactions of Grignard reagents including additions to carbonyl compounds, substitutions of alkyl/alkenyl/aryl halides, synthesis of ethers, amines, aldehydes and more. It also discusses the mechanisms and applications of important Grignard reactions such as the Bouveault, Benary, Bodrous, Dzhemilev and Kulinkovich reactions.
Organoborane or Organoboron compounds
Organoborane chemistry deals with organoboron compounds that contain carbon-boron bonds. Key reactions of organoboranes include hydroboration of alkenes, oxidation of organoboranes to alcohols, isomerization of organoboranes at high temperatures, protonolysis with carboxylic acids, and carbonylation with carbon monoxide. Carbonylation can produce aldehydes, ketones, or alcohols depending on reaction conditions and presence of migrating groups.
Mannich reaction
The Mannich reaction involves the condensation of an enolizable carbonyl compound, an aldehyde such as formaldehyde, and an amine to form a β-amino carbonyl compound known as a Mannich base. The reaction proceeds via the initial addition of the amine to the aldehyde to form an iminium ion intermediate, which then reacts with the enol form of the carbonyl compound to eliminate a proton and form the Mannich base product. While versatile building blocks in organic synthesis, the Mannich reaction has limitations in terms of substrate scope and control of regio- and stereoselectivity. Examples of applications include the synthesis of tropinone, a precursor of atropine, as well
Organomagnesium and lithium
Victor Grignard discovered the Grignard reagent in 1900, for which he won the Nobel Prize in Chemistry in 1912. Grignard reagents are organometallic compounds consisting of an alkyl, vinyl or aryl group bonded to magnesium. They react productively with aldehydes, ketones, esters, epoxides, and carbon dioxide to form alcohols, acids, and ketones. Organolithium reagents, which have a more ionic carbon-lithium bond, are more reactive than Grignard reagents and react similarly with functional groups like aldehydes and ketones. Grignard and organolithium reagents are important tools for carbon-carbon bond formation in organic synthesis.
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Organozinc compounds
1) Organozinc compounds are less reactive than organolithium and organomagnesium compounds due to their more covalent C-Zn bond, allowing preparation of functionalized derivatives.
2) Organozinc compounds are commonly prepared by reacting primary or secondary halides with zinc metal or Rieke zinc under inert atmosphere due to their sensitivity to oxidation.
3) Organozinc reagents are useful in organic syntheses such as Reformatsky reactions, Simmons-Smith cyclopropanation reactions, and cross-coupling reactions like Negishi and Fukuyama couplings.
Organolithium Compounds and Reactions
This PPT is usefull for aspirants of JEE-IIT, CSIR-NET and UPSC exams in CHEMISTRY section. It is also usefull for grduates and Post graduates students of Indian Universities.
organomagnesium-compounds.ppt
The document discusses organomagnesium halides (Grignard reagents). It describes how Grignard reagents are useful synthetic intermediates for carbon-carbon bond formation and are sources of nucleophilic carbanions. It summarizes several reactions of Grignard reagents including additions to carbonyl compounds, substitutions of alkyl/alkenyl/aryl halides, synthesis of ethers, amines, aldehydes and more. It also discusses the mechanisms and applications of important Grignard reactions such as the Bouveault, Benary, Bodrous, Dzhemilev and Kulinkovich reactions.
Organoborane or Organoboron compounds
Organoborane chemistry deals with organoboron compounds that contain carbon-boron bonds. Key reactions of organoboranes include hydroboration of alkenes, oxidation of organoboranes to alcohols, isomerization of organoboranes at high temperatures, protonolysis with carboxylic acids, and carbonylation with carbon monoxide. Carbonylation can produce aldehydes, ketones, or alcohols depending on reaction conditions and presence of migrating groups.
Mannich reaction
The Mannich reaction involves the condensation of an enolizable carbonyl compound, an aldehyde such as formaldehyde, and an amine to form a β-amino carbonyl compound known as a Mannich base. The reaction proceeds via the initial addition of the amine to the aldehyde to form an iminium ion intermediate, which then reacts with the enol form of the carbonyl compound to eliminate a proton and form the Mannich base product. While versatile building blocks in organic synthesis, the Mannich reaction has limitations in terms of substrate scope and control of regio- and stereoselectivity. Examples of applications include the synthesis of tropinone, a precursor of atropine, as well
Organomagnesium and lithium
Victor Grignard discovered the Grignard reagent in 1900, for which he won the Nobel Prize in Chemistry in 1912. Grignard reagents are organometallic compounds consisting of an alkyl, vinyl or aryl group bonded to magnesium. They react productively with aldehydes, ketones, esters, epoxides, and carbon dioxide to form alcohols, acids, and ketones. Organolithium reagents, which have a more ionic carbon-lithium bond, are more reactive than Grignard reagents and react similarly with functional groups like aldehydes and ketones. Grignard and organolithium reagents are important tools for carbon-carbon bond formation in organic synthesis.
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The document summarizes the Reformatsky reaction, an important carbon-carbon bond forming reaction discovered in 1887. It describes the reaction mechanism and conditions, such as the use of zinc, chromium, or indium as reagents and solvents like THF, DMF, or Et2O. The document outlines exceptions to the reaction, recent advancements like one-pot or chiral auxiliary introduced versions, and applications to the synthesis of various compounds, concluding that the Reformatsky reaction allows new C-C bond formation and β-hydroxy ester or lactone generation under neutral conditions.
Organolithium reagent hand written notes
The document discusses the benefits of meditation for reducing stress and anxiety. Regular meditation practice can help calm the mind and body by lowering heart rate and blood pressure. Making meditation a part of a daily routine, even if just 10-15 minutes per day, can have mental and physical health benefits over time by helping people feel more relaxed and focused.
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Neber rearrgment
The Neber rearrangement is a base-induced rearrangement of O-acylated ketoximes to the corresponding α-amino ketones. It was discovered in 1926 by Neber and Friedolsheim during their investigation of the Beckmann rearrangement. The Neber rearrangement has since become an important synthetic tool for synthesizing heterocycles that use amino ketones as intermediates. It proceeds through an alkoxide-induced rearrangement of the O-acylated ketoxime to form an α-amino ketone product. There are some limitations in that aldoximes do not undergo the rearrangement and substrates generally require a methylene group in the α-position.
Katsuki Sharpless Asymmetric Epoxidation and its Synthetic Applications
The Sharpless epoxidation reaction allows for the asymmetric epoxidation of allylic alcohols. It uses tert-butyl hydroperoxide as the oxidizing agent, titanium tetra isopropoxide as the catalyst, and a chiral tartrate ester ligand such as diethyl tartrate. The tartrate ligand provides chirality and controls the face selectivity of the epoxidation reaction. The Sharpless epoxidation has been widely used in the synthesis of pharmaceuticals, natural products, and other chemicals.
Wittig reaction
The Wittig reaction involves reacting an aldehyde or ketone with a triphenylphosphonium ylide to form an alkene and triphenylphosphine oxide. The reaction proceeds through betaine and oxaphosphetane intermediates. The stereochemistry of the product can be controlled by the reactants and conditions. Similar reactions are the Horner and Horner-Emmons-Wadsworth reactions, which use different reagents. The Wittig reaction is one of the main methods for synthesizing alkenes from carbonyl compounds.
Michael addition reaction
Michael addition reaction involves the conjugate addition of a nucleophile to an α,β-unsaturated carbonyl compound. It proceeds through a reversible 1,2-addition of the nucleophile to the β-carbon, which can then undergo irreversible proton elimination to form the more stable thermodynamic enolate product by removing the π-bond of the C=C. This reaction is useful for forming C-C bonds and natural products, with examples given of its application in multi-step syntheses using further carbonyl reactions like aldol condensation.
Ziegler natta catalysts.pptx
Zeigler Natta catalyst is an important class of chemical compounds remarfot their ability to effect the polymerization of olefin to polymers of high molecular weights and streoregular structures.
It was developed by German SCientist Karl Zeigler and Itanlian scientist Giulio Natta and they received the 1963 Nobel prize in chemistry.
It's a combination of organimetallics which consists of a complex Triethyl aluminum an transition metal halide(Titanium tetrachloride ) which analysis polymerization.
Other transition metal such as Vanadium,Zirconium,Chromium, have also proven effective.
Diazomethane reagent
Diazomethane is a highly reactive, toxic gas that is soluble in ether. It has the molecular formula CH2N2 and a boiling point of -23°C. Though explosive, it can be handled safely as an ethereal solution. Diazomethane is prepared through various methods including Pechmann's, Arndt and Amende's, and Backer's. It is used as a synthetic reagent for methylation of acids, alcohols, and phenols. It can also be used for homologation, ring expansion, synthesis of heterocyclic compounds, and generation of carbines through loss of nitrogen.
Sigmatropic rearrangement reactions (pericyclic reaction)
This document discusses sigmatropic rearrangements, a type of pericyclic reaction involving intramolecular migration of an atom or group across a conjugated pi system. It defines sigmatropic rearrangements and explains that they can occur through thermal or photochemical processes. The document categorizes different types of sigmatropic rearrangements such as Cope, Claisen, and [2,3] rearrangements. It provides examples of these reactions and discusses factors that determine reaction stereochemistry such as suprafacial versus antrafacial migration. The document also references several organic chemistry textbooks for further information on sigmatropic rearrangement mechanisms and applications.
Organotin compound
The document discusses organotin compounds and their chemical reactions. Organotin compounds contain tin in the +4 oxidation state, which allows it to form stable organic derivatives called stannanes. Due to its larger size compared to carbon, carbon substituents on the tin atom can be transferred via both radical and polar mechanisms in chemical reactions. The document also mentions that organotin compounds are used to reduce alkyl halides, carbonyl compounds, alkenes, and alkynes through various reaction pathways.
SMILES REARRANGEMENT [REACTION AND MECHANISM]
The Smiles rearrangement is an intramolecular aromatic nucleophilic substitution reaction. It involves the migration of a substituent X from one carbon of an aromatic ring to another, with an aromatic substituent Y acting as the nucleophile. A specific example provided is the migration of an SO2Ar group to the ortho position of an ArO- nucleophile, activated by an adjacent nitro group. The X group is usually S, SO, or SO2, while the Y nucleophile is typically the conjugate base of OH, NH2, NHR or SH, though even CH2 has been used.
synthetic Reagents and its application Diazomethane
Diazomethane is a yellow, poisonous, potentially explosive compound with the chemical formula CH2N2. It is a valuable synthetic reagent that is used for methylation reactions and in the synthesis of heterocyclic compounds. Diazomethane can be prepared through Pechmann's method involving the reaction of methylamine with ethyl chlorofomate or through hydrolysis of an ethereal solution of an N-methyl nitrosamide with aqueous base. It is chemically very reactive and transforms functional groups, making it useful for a variety of synthetic applications.
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FREE RADICALS , CARBENES AND NITRENES.pptx
This document discusses free radicals, carbenes, and nitrenes. It defines each type of species, describes their characteristics such as electronic structure and stability. The document outlines different types for each species and methods for their formation and synthetic applications. Free radicals form through bond homolysis and vary in stability based on alkyl substituents. Carbenes are divalent carbon species that exist as singlet or triplet forms with different hybridizations. Nitrenes are analogous to carbenes but with nitrogen and vary in stability and spin state. Examples of formation and trapping methods are provided along with sample synthetic reactions for each reactive intermediate.
Gilman Reagent
Gilman reagent, also known as organocopper reagents, are prepared by reacting organomagnesium, organolithium, or organozinc reagents with copper(I) salts. Gilman reagents react with a variety of electrophiles including acid chlorides, aldehydes, ketones, epoxides, and alkyl halides. Some common reactions of Gilman reagents are: 1) reactions with acid chlorides to form ketones, 2) coupling reactions between two different alkyl halides to form C-C bonds, and 3) conjugate addition reactions of the organocopper reagent to unsaturated carbonyl compounds like enones. Gilman reagents offer advantages over Grignard reagents for
Synthesis of benzimidazole
1) The document describes the procedure for synthesizing benzimidazole from o-phenylenediamine and formic acid.
2) Key steps include heating a mixture of o-phenylenediamine and excess formic acid at 100°C for 2 hours, then making the reaction mixture alkaline with sodium hydroxide to precipitate crude benzimidazole.
3) Benzimidazole has biological applications as an active component in anthelmintic and antiulcer drugs, and its derivatives also show antimicrobial and anticancer properties.
Synthesis of Coumarins
This document summarizes the synthesis of 7-Hydroxy-4-Methyl Coumarin via the Pechmann condensation reaction of resorcinol and ethyl acetoacetate in the presence of concentrated sulfuric acid. Coumarins are an important class of compounds that are found in plants and have various medical applications such as antimicrobial and antitumor properties. The procedure involves cooling concentrated sulfuric acid to below 5°C and adding a solution of resorcinol and ethyl acetoacetate dropwise, followed by workup to obtain an impure product that is recrystallized from ethanol.
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Organolithium reagent hand written notes
The document discusses the benefits of meditation for reducing stress and anxiety. Regular meditation practice can help calm the mind and body by lowering heart rate and blood pressure. Making meditation a part of a daily routine, even if just 10-15 minutes per day, can have mental and physical health benefits over time by helping people feel more relaxed and focused.
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These slides will introduce you readers about synthesis of Longifolene through its retrosynthestic analysis. It consist of synthetic and retrosynthetic module of Longifolene given by different scientists
Neber rearrgment
The Neber rearrangement is a base-induced rearrangement of O-acylated ketoximes to the corresponding α-amino ketones. It was discovered in 1926 by Neber and Friedolsheim during their investigation of the Beckmann rearrangement. The Neber rearrangement has since become an important synthetic tool for synthesizing heterocycles that use amino ketones as intermediates. It proceeds through an alkoxide-induced rearrangement of the O-acylated ketoxime to form an α-amino ketone product. There are some limitations in that aldoximes do not undergo the rearrangement and substrates generally require a methylene group in the α-position.
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The Sharpless epoxidation reaction allows for the asymmetric epoxidation of allylic alcohols. It uses tert-butyl hydroperoxide as the oxidizing agent, titanium tetra isopropoxide as the catalyst, and a chiral tartrate ester ligand such as diethyl tartrate. The tartrate ligand provides chirality and controls the face selectivity of the epoxidation reaction. The Sharpless epoxidation has been widely used in the synthesis of pharmaceuticals, natural products, and other chemicals.
Wittig reaction
The Wittig reaction involves reacting an aldehyde or ketone with a triphenylphosphonium ylide to form an alkene and triphenylphosphine oxide. The reaction proceeds through betaine and oxaphosphetane intermediates. The stereochemistry of the product can be controlled by the reactants and conditions. Similar reactions are the Horner and Horner-Emmons-Wadsworth reactions, which use different reagents. The Wittig reaction is one of the main methods for synthesizing alkenes from carbonyl compounds.
Michael addition reaction
Michael addition reaction involves the conjugate addition of a nucleophile to an α,β-unsaturated carbonyl compound. It proceeds through a reversible 1,2-addition of the nucleophile to the β-carbon, which can then undergo irreversible proton elimination to form the more stable thermodynamic enolate product by removing the π-bond of the C=C. This reaction is useful for forming C-C bonds and natural products, with examples given of its application in multi-step syntheses using further carbonyl reactions like aldol condensation.
Ziegler natta catalysts.pptx
Zeigler Natta catalyst is an important class of chemical compounds remarfot their ability to effect the polymerization of olefin to polymers of high molecular weights and streoregular structures.
It was developed by German SCientist Karl Zeigler and Itanlian scientist Giulio Natta and they received the 1963 Nobel prize in chemistry.
It's a combination of organimetallics which consists of a complex Triethyl aluminum an transition metal halide(Titanium tetrachloride ) which analysis polymerization.
Other transition metal such as Vanadium,Zirconium,Chromium, have also proven effective.
Diazomethane reagent
Diazomethane is a highly reactive, toxic gas that is soluble in ether. It has the molecular formula CH2N2 and a boiling point of -23°C. Though explosive, it can be handled safely as an ethereal solution. Diazomethane is prepared through various methods including Pechmann's, Arndt and Amende's, and Backer's. It is used as a synthetic reagent for methylation of acids, alcohols, and phenols. It can also be used for homologation, ring expansion, synthesis of heterocyclic compounds, and generation of carbines through loss of nitrogen.
Sigmatropic rearrangement reactions (pericyclic reaction)
This document discusses sigmatropic rearrangements, a type of pericyclic reaction involving intramolecular migration of an atom or group across a conjugated pi system. It defines sigmatropic rearrangements and explains that they can occur through thermal or photochemical processes. The document categorizes different types of sigmatropic rearrangements such as Cope, Claisen, and [2,3] rearrangements. It provides examples of these reactions and discusses factors that determine reaction stereochemistry such as suprafacial versus antrafacial migration. The document also references several organic chemistry textbooks for further information on sigmatropic rearrangement mechanisms and applications.
Organotin compound
The document discusses organotin compounds and their chemical reactions. Organotin compounds contain tin in the +4 oxidation state, which allows it to form stable organic derivatives called stannanes. Due to its larger size compared to carbon, carbon substituents on the tin atom can be transferred via both radical and polar mechanisms in chemical reactions. The document also mentions that organotin compounds are used to reduce alkyl halides, carbonyl compounds, alkenes, and alkynes through various reaction pathways.
SMILES REARRANGEMENT [REACTION AND MECHANISM]
The Smiles rearrangement is an intramolecular aromatic nucleophilic substitution reaction. It involves the migration of a substituent X from one carbon of an aromatic ring to another, with an aromatic substituent Y acting as the nucleophile. A specific example provided is the migration of an SO2Ar group to the ortho position of an ArO- nucleophile, activated by an adjacent nitro group. The X group is usually S, SO, or SO2, while the Y nucleophile is typically the conjugate base of OH, NH2, NHR or SH, though even CH2 has been used.
synthetic Reagents and its application Diazomethane
Diazomethane is a yellow, poisonous, potentially explosive compound with the chemical formula CH2N2. It is a valuable synthetic reagent that is used for methylation reactions and in the synthesis of heterocyclic compounds. Diazomethane can be prepared through Pechmann's method involving the reaction of methylamine with ethyl chlorofomate or through hydrolysis of an ethereal solution of an N-methyl nitrosamide with aqueous base. It is chemically very reactive and transforms functional groups, making it useful for a variety of synthetic applications.
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FREE RADICALS , CARBENES AND NITRENES.pptx
This document discusses free radicals, carbenes, and nitrenes. It defines each type of species, describes their characteristics such as electronic structure and stability. The document outlines different types for each species and methods for their formation and synthetic applications. Free radicals form through bond homolysis and vary in stability based on alkyl substituents. Carbenes are divalent carbon species that exist as singlet or triplet forms with different hybridizations. Nitrenes are analogous to carbenes but with nitrogen and vary in stability and spin state. Examples of formation and trapping methods are provided along with sample synthetic reactions for each reactive intermediate.
Gilman Reagent
Gilman reagent, also known as organocopper reagents, are prepared by reacting organomagnesium, organolithium, or organozinc reagents with copper(I) salts. Gilman reagents react with a variety of electrophiles including acid chlorides, aldehydes, ketones, epoxides, and alkyl halides. Some common reactions of Gilman reagents are: 1) reactions with acid chlorides to form ketones, 2) coupling reactions between two different alkyl halides to form C-C bonds, and 3) conjugate addition reactions of the organocopper reagent to unsaturated carbonyl compounds like enones. Gilman reagents offer advantages over Grignard reagents for
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Preparation of p-nitroacetanilide from Acetanilide
Semi Micro Qualitative Organic chemistry lab manual
Semi Micro Qualitative Organic chemistry lab manual
M.Sc. Organic Chemistry Student Project Presentation
M.Sc. Organic Chemistry Student Project Presentation
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(June 12, 2024) Webinar: Development of PET theranostics targeting the molecu...
(June 12, 2024) Webinar: Development of PET theranostics targeting the molecu...Scintica Instrumentation
Targeting Hsp90 and its pathogen Orthologs with Tethered Inhibitors as a Diagnostic and Therapeutic Strategy for cancer and infectious diseases with Dr. Timothy Haystead.Applied Science: Thermodynamics, Laws & Methodology.pdf
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
ESR spectroscopy in liquid food and beverages.pptx
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
Pests of Storage_Identification_Dr.UPR.pdf
InIndia-post-harvestlosses-unscientificstorage,insects,rodents,micro-organismsetc.,accountforabout10percentoftotalfoodgrains
Graininfestation
Directdamage
Indirectly
•theexuviae,skin,deadinsects
•theirexcretawhichmakefoodunfitforhumanconsumption
About600speciesofinsectshavebeenassociatedwithstoredgrainproducts
100speciesofinsectpestsofstoredproductscauseeconomiclosses
The cost of acquiring information by natural selection
This is a short talk that I gave at the Banff International Research Station workshop on Modeling and Theory in Population Biology. The idea is to try to understand how the burden of natural selection relates to the amount of information that selection puts into the genome.
It's based on the first part of this research paper:
The cost of information acquisition by natural selection
Ryan Seamus McGee, Olivia Kosterlitz, Artem Kaznatcheev, Benjamin Kerr, Carl T. Bergstrom
bioRxiv 2022.07.02.498577; doi: https://doi.org/10.1101/2022.07.02.498577
Immersive Learning That Works: Research Grounding and Paths Forward
We will metaverse into the essence of immersive learning, into its three dimensions and conceptual models. This approach encompasses elements from teaching methodologies to social involvement, through organizational concerns and technologies. Challenging the perception of learning as knowledge transfer, we introduce a 'Uses, Practices & Strategies' model operationalized by the 'Immersive Learning Brain' and ‘Immersion Cube’ frameworks. This approach offers a comprehensive guide through the intricacies of immersive educational experiences and spotlighting research frontiers, along the immersion dimensions of system, narrative, and agency. Our discourse extends to stakeholders beyond the academic sphere, addressing the interests of technologists, instructional designers, and policymakers. We span various contexts, from formal education to organizational transformation to the new horizon of an AI-pervasive society. This keynote aims to unite the iLRN community in a collaborative journey towards a future where immersive learning research and practice coalesce, paving the way for innovative educational research and practice landscapes.
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
学校原件一模一样【微信：741003700 】《(salfor毕业证书)索尔福德大学毕业证》【微信：741003700 】学位证，留信认证（真实可查，永久存档）原件一模一样纸张工艺/offer、雅思、外壳等材料/诚信可靠,可直接看成品样本，帮您解决无法毕业带来的各种难题！外壳，原版制作，诚信可靠，可直接看成品样本。行业标杆！精益求精，诚心合作，真诚制作！多年品质 ,按需精细制作，24小时接单,全套进口原装设备。十五年致力于帮助留学生解决难题，包您满意。
本公司拥有海外各大学样板无数，能完美还原。
1:1完美还原海外各大学毕业材料上的工艺：水印，阴影底纹，钢印LOGO烫金烫银，LOGO烫金烫银复合重叠。文字图案浮雕、激光镭射、紫外荧光、温感、复印防伪等防伪工艺。材料咨询办理、认证咨询办理请加学历顾问Q/微741003700
【主营项目】
一.毕业证【q微741003700】成绩单、使馆认证、教育部认证、雅思托福成绩单、学生卡等！
二.真实使馆公证(即留学回国人员证明,不成功不收费)
三.真实教育部学历学位认证（教育部存档！教育部留服网站永久可查）
四.办理各国各大学文凭(一对一专业服务,可全程监控跟踪进度)
如果您处于以下几种情况：
◇在校期间，因各种原因未能顺利毕业……拿不到官方毕业证【q/微741003700】
◇面对父母的压力，希望尽快拿到；
◇不清楚认证流程以及材料该如何准备；
◇回国时间很长，忘记办理；
◇回国马上就要找工作，办给用人单位看；
◇企事业单位必须要求办理的
◇需要报考公务员、购买免税车、落转户口
◇申请留学生创业基金
留信网认证的作用:
1:该专业认证可证明留学生真实身份
2:同时对留学生所学专业登记给予评定
3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
The technology uses reclaimed CO₂ as the dyeing medium in a closed loop process. When pressurized, CO₂ becomes supercritical (SC-CO₂). In this state CO₂ has a very high solvent power, allowing the dye to dissolve easily.
Authoring a personal GPT for your research and practice: How we created the Q...
Thematic analysis in qualitative research is a time-consuming and systematic task, typically done using teams. Team members must ground their activities on common understandings of the major concepts underlying the thematic analysis, and define criteria for its development. However, conceptual misunderstandings, equivocations, and lack of adherence to criteria are challenges to the quality and speed of this process. Given the distributed and uncertain nature of this process, we wondered if the tasks in thematic analysis could be supported by readily available artificial intelligence chatbots. Our early efforts point to potential benefits: not just saving time in the coding process but better adherence to criteria and grounding, by increasing triangulation between humans and artificial intelligence. This tutorial will provide a description and demonstration of the process we followed, as two academic researchers, to develop a custom ChatGPT to assist with qualitative coding in the thematic data analysis process of immersive learning accounts in a survey of the academic literature: QUAL-E Immersive Learning Thematic Analysis Helper. In the hands-on time, participants will try out QUAL-E and develop their ideas for their own qualitative coding ChatGPT. Participants that have the paid ChatGPT Plus subscription can create a draft of their assistants. The organizers will provide course materials and slide deck that participants will be able to utilize to continue development of their custom GPT. The paid subscription to ChatGPT Plus is not required to participate in this workshop, just for trying out personal GPTs during it.
Katherine Romanak - Geologic CO2 Storage.pdf
Presented at June 6-7 Texas Alliance of Groundwater Districts Business Meeting
Bob Reedy - Nitrate in Texas Groundwater.pdf
Presented at June 6-7 Texas Alliance of Groundwater Districts Business Meeting
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Current descriptions of immersive learning cases are often difficult or impossible to compare. This is due to a myriad of different options on what details to include, which aspects are relevant, and on the descriptive approaches employed. Also, these aspects often combine very specific details with more general guidelines or indicate intents and rationales without clarifying their implementation. In this paper we provide a method to describe immersive learning cases that is structured to enable comparisons, yet flexible enough to allow researchers and practitioners to decide which aspects to include. This method leverages a taxonomy that classifies educational aspects at three levels (uses, practices, and strategies) and then utilizes two frameworks, the Immersive Learning Brain and the Immersion Cube, to enable a structured description and interpretation of immersive learning cases. The method is then demonstrated on a published immersive learning case on training for wind turbine maintenance using virtual reality. Applying the method results in a structured artifact, the Immersive Learning Case Sheet, that tags the case with its proximal uses, practices, and strategies, and refines the free text case description to ensure that matching details are included. This contribution is thus a case description method in support of future comparative research of immersive learning cases. We then discuss how the resulting description and interpretation can be leveraged to change immersion learning cases, by enriching them (considering low-effort changes or additions) or innovating (exploring more challenging avenues of transformation). The method holds significant promise to support better-grounded research in immersive learning.
Mending Clothing to Support Sustainable Fashion_CIMaR 2024.pdf
Ozturkcan, S., Berndt, A., & Angelakis, A. (2024). Mending clothing to support sustainable fashion. Presented at the 31st Annual Conference by the Consortium for International Marketing Research (CIMaR), 10-13 Jun 2024, University of Gävle, Sweden.
Equivariant neural networks and representation theory
Or: Beyond linear.
Abstract: Equivariant neural networks are neural networks that incorporate symmetries. The nonlinear activation functions in these networks result in interesting nonlinear equivariant maps between simple representations, and motivate the key player of this talk: piecewise linear representation theory.
Disclaimer: No one is perfect, so please mind that there might be mistakes and typos.
dtubbenhauer@gmail.com
Corrected slides: dtubbenhauer.com/talks.html
SAR of Medicinal Chemistry 1st by dk.pdf
In this presentation include the prototype drug SAR on thus or with their examples .
Syllabus of Second Year B. Pharmacy
2019 PATTERN.
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Basics of crystallography, crystal systems, classes and different forms
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(June 12, 2024) Webinar: Development of PET theranostics targeting the molecu...
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Applied Science: Thermodynamics, Laws & Methodology.pdf
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ESR spectroscopy in liquid food and beverages.pptx
ESR spectroscopy in liquid food and beverages.pptx
The cost of acquiring information by natural selection
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Immersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths Forward
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
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Authoring a personal GPT for your research and practice: How we created the Q...
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Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Mending Clothing to Support Sustainable Fashion_CIMaR 2024.pdf
Mending Clothing to Support Sustainable Fashion_CIMaR 2024.pdf
Equivariant neural networks and representation theory
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