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Cementum
Dr.Nour Hayel Kasbari
• One of the four tissues of the periodontuim.
• Thickest at the root apex and in the interradicular
areas.
• Cementum is continuous with the PDL on it’s outer
surface and firmly adherent to dentine.
• It's prime function is to give attachment to collagen
fibers of the PDL.
• It is involved in tooth repair and regeneration.
Three patters for the arrangement of the
cement-enamel junction
Physical properties
 Cementum is pale yellow.
 Softer than dentine and more permeable(permeability
decreases with age).
 Relative softness with its thinness cervically means that it can
be removed readily with abrasion when gingival recession
exposes the root causing sensitivity.
Chemical properties
 Contains organic and inorganic material.
 The principle inorganic material is hyroxyapatite, calcium
is also found ( in higher levels than enamel and dentine).
 The organic matrix is primarily collagen type I.
 Other non-collagenous proteins: bone sialoprotein,
dentine sialoprotein, fibronectin..
 CAP ( cementum derived attachment protein) promote
attachment of mesenchymal cells to extracellular matrix,
and maybe a marker to diffrentiate cementum and bone.
 Cementum is rich in GAGs esp. chondroitin sulphate and
located around cementum lacunae.
Classification of cementum
1. Based on the presence or absence of cells.
2. Based on the nature and origin of the organic
matrix.
3. Based on the presence or absence of cells and
on the nature and origin of the organic matrix.
1.Based on the presence or absence of cells.
A. Acellular cementum (primary cementum) : formes first
Does not contain cells , covers the root adjacent to dentine.
B. Cellular cementum(secondary cementum): contains
cemetocytes, formation rate is slow , it is well mineralized,
found mainly in the apical area covering apical area overlying
acellular cementum.
 Although usually cellular cementum overlie acellular
cementum the reverse may occur , or the two varients of the
cementum to alternate.
2.Based on the nature and origin of the organic matrix
cementum derives it's organic matrix from two
sources:
A.Extrensic fibers: they are sharpey fibers from the PDL,
these fibers continue in the same direction as the principle
fibers of the ligament.
B.Intrinsic fibers: derived from cementoblasts, run parallel to
the root surface and at right angle to the extrensic fibers.
C.Mixed fibre cementum : both extrensic and intrinsic fibers are
present.
3-Based on the presence or absence of cells and on
the nature and origin of the organic matrix.
A. Acellular extrensic fibre cementum (AEFC):
 Corresponds with acellular cementum, found in the
cervical two thirds.
 Fibers derived from sharpy fibers.
 Formed slowly and root surface is smooth.
B. Cellular intrinsic fibre cementum(CIFC):
 Corrosponds to cellular cementum .
 Composed only of intrinsic fibers running parallel to the
root surface.
 Has no role in tooth attachment since there's no sharpy
fibers.
 Less cellular than bone and has a cemetoid seam on its
outer surface.
C.mixed fibre cementum:
 Collagen fibers are both extrinsic and intrinsic .
 Intrinsic fibers are fewer in number and run between the
larger ovoid or round extrinsic fibers.
 If the formation rate is slow cementum may be termed
acellular mixed fibre cementum.
 If the formation rate is fast, cementum may be termed
cellular mixed fibre cementum.
D. Afibrillar cementum
 Contains no collagen fibers.
 Sparsely distributed and consists of a well mineralized
ground substances that maybe of epithelial origin.
 It's thin, acellular layer covers cervical enamel or in between
fibrillar cementum and dentine.
 Formed following the loss of reduced enamel epithelium.
A. Mineralized intrinsic fibers
B.mineralized extrinsic fibers
Cementum-dentine junction
 This junction is of clinical importance because of the
processes involved in maintaining tooth function while
repairing diseased root.
 Intermediate layer found between cementum and
dentine.
 This layer is characterization by wide , irregular ,
branching spaces which interconnect with dentinal
tubules.
 Intermediate layer may function as a permeability barrier
preceding cementogenesis.
 Also related to regeneration of the periodontuim following
periodontal surgery.
• Cementum near the periodontuim is not
homogenous because of the ongoing calcification
and the presence of sharpey fibers.
• At deeper levels , closer to dentine acellular
cementum resembles dentine.
Resorption and repair of
cementum
• Cementum is less susceptible to resorption than bone,
but localised areas of resorption are found associated
with micro trauma.
• Resorption is carried out out by multinucleated
odontoclasts.
• The unmineralized surface layer of collagen protects
against resorption.
• Repair occurs as a layer of formative cells
(cementoblasts) depositing a thin layer of
precementum.
• Reversal line separates the repair tissue from
underlying dental tissues.
• When the speed of formation of the repair tissue is
slow the repair tissue cannot be distinguished
histologically, and it is well mineralized
• If the speed is rapid it resembles woven bone.
Clinical consideration
cemental callus
• sometimes form around root fractures
• Does not usually remodel to the original
dimensions of the tooth.
cementicles
 Are small globular masses of cementum
attached to the root or free in the PDL
 As a result of microtrauma
 More common in apical and middle thirds of the
root and in bifurcationa areas
• Local hypercementosis
• In cases of chronic periapical infections.
• Fusion of adjacent teeth called concrescence.
• Hypercementosis affecting all teeth is associated
with Paget's disease .
Hpophosphatasia
result in reduction of tissue non- specific alkaline
phosphatase which causes significant reduction in
amount of cementum formed, as a result the
attachment of the PDL Fibers is compromised which
causes premature loss of teeth ( both primary and
permenant dentition).
Oral Histology - Cementum

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Oral Histology - Cementum

  • 2. • One of the four tissues of the periodontuim. • Thickest at the root apex and in the interradicular areas. • Cementum is continuous with the PDL on it’s outer surface and firmly adherent to dentine. • It's prime function is to give attachment to collagen fibers of the PDL. • It is involved in tooth repair and regeneration.
  • 3. Three patters for the arrangement of the cement-enamel junction
  • 4. Physical properties  Cementum is pale yellow.  Softer than dentine and more permeable(permeability decreases with age).  Relative softness with its thinness cervically means that it can be removed readily with abrasion when gingival recession exposes the root causing sensitivity.
  • 5. Chemical properties  Contains organic and inorganic material.  The principle inorganic material is hyroxyapatite, calcium is also found ( in higher levels than enamel and dentine).  The organic matrix is primarily collagen type I.  Other non-collagenous proteins: bone sialoprotein, dentine sialoprotein, fibronectin..  CAP ( cementum derived attachment protein) promote attachment of mesenchymal cells to extracellular matrix, and maybe a marker to diffrentiate cementum and bone.  Cementum is rich in GAGs esp. chondroitin sulphate and located around cementum lacunae.
  • 6. Classification of cementum 1. Based on the presence or absence of cells. 2. Based on the nature and origin of the organic matrix. 3. Based on the presence or absence of cells and on the nature and origin of the organic matrix.
  • 7. 1.Based on the presence or absence of cells. A. Acellular cementum (primary cementum) : formes first Does not contain cells , covers the root adjacent to dentine. B. Cellular cementum(secondary cementum): contains cemetocytes, formation rate is slow , it is well mineralized, found mainly in the apical area covering apical area overlying acellular cementum.  Although usually cellular cementum overlie acellular cementum the reverse may occur , or the two varients of the cementum to alternate.
  • 8.
  • 9.
  • 10. 2.Based on the nature and origin of the organic matrix cementum derives it's organic matrix from two sources: A.Extrensic fibers: they are sharpey fibers from the PDL, these fibers continue in the same direction as the principle fibers of the ligament. B.Intrinsic fibers: derived from cementoblasts, run parallel to the root surface and at right angle to the extrensic fibers. C.Mixed fibre cementum : both extrensic and intrinsic fibers are present.
  • 11.
  • 12. 3-Based on the presence or absence of cells and on the nature and origin of the organic matrix. A. Acellular extrensic fibre cementum (AEFC):  Corresponds with acellular cementum, found in the cervical two thirds.  Fibers derived from sharpy fibers.  Formed slowly and root surface is smooth. B. Cellular intrinsic fibre cementum(CIFC):  Corrosponds to cellular cementum .  Composed only of intrinsic fibers running parallel to the root surface.  Has no role in tooth attachment since there's no sharpy fibers.  Less cellular than bone and has a cemetoid seam on its outer surface.
  • 13.
  • 14. C.mixed fibre cementum:  Collagen fibers are both extrinsic and intrinsic .  Intrinsic fibers are fewer in number and run between the larger ovoid or round extrinsic fibers.  If the formation rate is slow cementum may be termed acellular mixed fibre cementum.  If the formation rate is fast, cementum may be termed cellular mixed fibre cementum. D. Afibrillar cementum  Contains no collagen fibers.  Sparsely distributed and consists of a well mineralized ground substances that maybe of epithelial origin.  It's thin, acellular layer covers cervical enamel or in between fibrillar cementum and dentine.  Formed following the loss of reduced enamel epithelium.
  • 15.
  • 16. A. Mineralized intrinsic fibers B.mineralized extrinsic fibers
  • 17. Cementum-dentine junction  This junction is of clinical importance because of the processes involved in maintaining tooth function while repairing diseased root.  Intermediate layer found between cementum and dentine.  This layer is characterization by wide , irregular , branching spaces which interconnect with dentinal tubules.  Intermediate layer may function as a permeability barrier preceding cementogenesis.  Also related to regeneration of the periodontuim following periodontal surgery.
  • 18.
  • 19. • Cementum near the periodontuim is not homogenous because of the ongoing calcification and the presence of sharpey fibers. • At deeper levels , closer to dentine acellular cementum resembles dentine.
  • 20. Resorption and repair of cementum • Cementum is less susceptible to resorption than bone, but localised areas of resorption are found associated with micro trauma. • Resorption is carried out out by multinucleated odontoclasts. • The unmineralized surface layer of collagen protects against resorption. • Repair occurs as a layer of formative cells (cementoblasts) depositing a thin layer of precementum. • Reversal line separates the repair tissue from underlying dental tissues.
  • 21. • When the speed of formation of the repair tissue is slow the repair tissue cannot be distinguished histologically, and it is well mineralized • If the speed is rapid it resembles woven bone.
  • 22. Clinical consideration cemental callus • sometimes form around root fractures • Does not usually remodel to the original dimensions of the tooth. cementicles  Are small globular masses of cementum attached to the root or free in the PDL  As a result of microtrauma  More common in apical and middle thirds of the root and in bifurcationa areas
  • 23.
  • 24. • Local hypercementosis • In cases of chronic periapical infections. • Fusion of adjacent teeth called concrescence. • Hypercementosis affecting all teeth is associated with Paget's disease . Hpophosphatasia result in reduction of tissue non- specific alkaline phosphatase which causes significant reduction in amount of cementum formed, as a result the attachment of the PDL Fibers is compromised which causes premature loss of teeth ( both primary and permenant dentition).