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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2260
Optical Disc Detection, Localization and Glaucoma Identification of
Retinal Fundus Image
Priya Hankare1 , Purvi Kakasagar2, Bhaviya Jagad3, Dhwanil Barot4, Omkar Joshi5
2-5Department of Electronics and Telecommunications Engineering, K.J. SOMAIYA INSTITUTE OF ENGINEERING
AND INFORMATION TECHNOLOGY, Mumbai, Maharashtra, India
1 Assistant Professor, Department of electronics and Telecommunications,KJSIEIT,Mumbai,Maharashtra,India
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - The major cause of blindness in
the world is diabetic-related eye disease. Various parts of
the body get affected due to complication of diabetes.
Diabetic retinopathy is termed as high level of glucose in the
retina, which may cause blurring of the vision and can lead
to blindness. To avoid further damage of vision, time to time
testing of retina is done to detect the early stages of diabetic
retinopathy. This project aims for detection of Diabetic
retinopathy (DR) by taking cup to disc ratio into
consideration. Morphological processing techniques are
used on the fundus images to extract features of optic disc
such as area of disc and area of cup, we calculate the area of
each extracted feature. Depending on the area of cup to disc
ratio we identify the severity of the disease. Depending on
the severity of disease, treatment measures can be analysed.
To make it more user friendly GUI in MATLAB is used and to
track the progress of disease, database is maintained. By
making use of this project, ophthalmologists will surely be
able to track the severity of disease and make it more
efficient to keep Diabetic retinopathy (DR) under control.
KeyWords: Diabetic Retinopathy(DR) , Fundus Camera,
Morphological Operations, Segmentation.
1.INTRODUCTION
In this project, an approach is made to identify the image
given by the patient. The image is classified into 3
categories: Normal, Non-Proliferative Diabetic
Retinopathy, Proliferative Diabetic
Retinopathy.Processing of the fundus image is done so
that various diseases in the eye can be obtained such as
haemorrhages. Hard exudates, laser treatment marks, etc.
Fundus camera has to be used for taking image of a retina.
This process is useful for patients who cannot regularly
visit doctor and thus sending an image of their retina will
be useful for further diagnosis. This project aims to reduce
the blindness caused due to diabetic retinopathy by
regular scanning of the retina and processing it to
determine the health of the eye.
2. LITERATURE SURVEY
An image processing system has the features to help the
ophthalmologist in diagnosing eye diabetic retinopathy
diseases better. It aims to detect the changes in retina. The
classification system which states the DR stages are based on
the values obtained of cup and disc. [1] The system can help
ophthalmologist to perform early screening on diabetes
patients. The proposed method used processes fundus
image database obtained from Hospital. Together with
other suitable retinal features extraction and classification
methods, this segmentation method can form the basis of a
fast and easy to use diagnostic support tool for diabetic
retinopathy, which will give a huge advantage in terms of
improved access to mass screening people for risk or
presence of diabetes.
2.1 TYPES OF DISEASES: -
Microaneurysms –
The walls i.e. capillary walls are weakened which leads
them to leakages.
Haemorrhages –
The capillaries that are weakened are ruptured which
causes small dots or haemorrhages on the retinal layers.
[2]
Exudates –
The proteins are leaked from retinal blood vessels. These
look like yellow flakes. These are termed as hard exudates.
These are the residues caused from leakage from damaged
capillaries. The most common cause of hard exudates are
DR [3].
Intraretinal Microvascular Abnormality (IrMA): -
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2261
Intraretinal microvascular abnormalities (or IrMAs) are
the cause of dilation of blood vessels also known as
capillaries within the retina.They appear as abnormal
branching . [4]
Fig 1: Healthy retina vs Diabetic Retinopathy affected eye.
Fig 2: Healthy optic nerve vs optic nerve in eye with
glaucoma
3. IMPLEMENTATION
Firstly, Fundus camera will be used to take images of
retina. Retina images contains optical disc, blood vessels.
This project is focused on optic disc. So the size of optic
disc will be cropped and saved for further processing. The
cropped image of optic disc will be converted into binary
image. Then the cup of the disc will be cropped from the
retina image. Same processing techniques will be used for
the cup. The threshold levels of the two cropped images
will be different. The ratio of cup-to-disc ratio is important
for determining the severity of the disease. The ratio
values can be different for various reasons but the range is
majorly fixed for normal, mild or heavily DR affected eyes.
Fig 3: Handheld Fundus Camera
 Taking the image of retina by using fundus
camera which has microscope attached to high
end camera, back of the eye is captured.
Colour Image of Eye Effected by Glaucoma
 Then this captured image is transferred to the
computer and is stored to maintain the database
of patient.
 This retina image is colour image, we load this
image into the application and then the optic disc
is cropped manually.
Colour Image of Optic Disc
 We first detect the optic disc from the cropped
image for which we make use of thresholding, i.e.
we set threshold values for R, G and B.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2262
 Counting the black and the white pixels we get the
area of the optic disc.
 Similarly, we set different thresholding value for
cup and get the area of the cup.
Binary Image of Cup
 By using this values of optic disc and cup, we find
out the cup to disc ratio and depending on the
value result is displayed, i.e. severity of the
disease (HIGH, MEDIUM, NORMAL).
4.RESULT & CONCLUSION
Original Cropped Optic
Disc
Cup
Early detection of diabetic retinopathy is very important
because it enables timely treatment that can ease the
burden of the disease on the patients and their families by
maintaining a sufficient quality of vision and preventing
severe vision loss and blindness. Positive economic
benefits can be achieved with early detection of diabetic
retinopathy because patients can be more productive and
can live without special medical care. Image processing
and analysis algorithms are important because they
enable development of automated systems for early
detection of diabetic retinopathy.
ACKNOWLEDGEMENT
We would like to thank Prof. Priya Hankare for her
support and guidance. Also we would like to thank Aditya
Jyot Hospital for their help in providing us retina pictures
and solving all our queries.
REFERENCES
[1] Ahmad Zikri Rozlan ,Hadzli Hashim ,Syed Farid Syed
Adnan ,Chen Ai Hong ,Miswanudin Mahyudin. “A proposed
diabetic retinopathy classification algorithm with
statistical inference of exudates detection”. IEEE
Xplore.Web.11 September.2014
[2] Dr. Olivia Scott, “Diabetic Retinopathy and Diabetic Eye
Problems”. Web.20 January 2016.
[3] Anonymous
[4] Chris Kirkpatrick, “Intraretinal Microvascular
Abnormality (IrMA)”.2013
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2263
Purvi Kakasagar,Bachelor of
Engineering from K.J. SOMAIYA
INSTITUTE OF ENGINEERING
AND INFORMATION
TECHNOLOGY, Mumbai,
Maharashtra, India
Bhaviya Jagad, Bachelor of
Engineering from K.J. SOMAIYA
INSTITUTE OF ENGINEERING
AND INFORMATION
TECHNOLOGY, Mumbai,
Maharashtra, India
Dhwanil Barot, Bachelor of
Engineering from K.J. SOMAIYA
INSTITUTE OF ENGINEERING
AND INFORMATION
TECHNOLOGY, Mumbai,
Maharashtra, India
Omkar Joshi, Bachelor of
Engineering from K.J. SOMAIYA
INSTITUTE OF ENGINEERING
AND INFORMATION
TECHNOLOGY, Mumbai,
Maharashtra, India

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Optical Disc Detection, Localization and Glaucoma Identification of Retinal Fundus Image

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2260 Optical Disc Detection, Localization and Glaucoma Identification of Retinal Fundus Image Priya Hankare1 , Purvi Kakasagar2, Bhaviya Jagad3, Dhwanil Barot4, Omkar Joshi5 2-5Department of Electronics and Telecommunications Engineering, K.J. SOMAIYA INSTITUTE OF ENGINEERING AND INFORMATION TECHNOLOGY, Mumbai, Maharashtra, India 1 Assistant Professor, Department of electronics and Telecommunications,KJSIEIT,Mumbai,Maharashtra,India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - The major cause of blindness in the world is diabetic-related eye disease. Various parts of the body get affected due to complication of diabetes. Diabetic retinopathy is termed as high level of glucose in the retina, which may cause blurring of the vision and can lead to blindness. To avoid further damage of vision, time to time testing of retina is done to detect the early stages of diabetic retinopathy. This project aims for detection of Diabetic retinopathy (DR) by taking cup to disc ratio into consideration. Morphological processing techniques are used on the fundus images to extract features of optic disc such as area of disc and area of cup, we calculate the area of each extracted feature. Depending on the area of cup to disc ratio we identify the severity of the disease. Depending on the severity of disease, treatment measures can be analysed. To make it more user friendly GUI in MATLAB is used and to track the progress of disease, database is maintained. By making use of this project, ophthalmologists will surely be able to track the severity of disease and make it more efficient to keep Diabetic retinopathy (DR) under control. KeyWords: Diabetic Retinopathy(DR) , Fundus Camera, Morphological Operations, Segmentation. 1.INTRODUCTION In this project, an approach is made to identify the image given by the patient. The image is classified into 3 categories: Normal, Non-Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy.Processing of the fundus image is done so that various diseases in the eye can be obtained such as haemorrhages. Hard exudates, laser treatment marks, etc. Fundus camera has to be used for taking image of a retina. This process is useful for patients who cannot regularly visit doctor and thus sending an image of their retina will be useful for further diagnosis. This project aims to reduce the blindness caused due to diabetic retinopathy by regular scanning of the retina and processing it to determine the health of the eye. 2. LITERATURE SURVEY An image processing system has the features to help the ophthalmologist in diagnosing eye diabetic retinopathy diseases better. It aims to detect the changes in retina. The classification system which states the DR stages are based on the values obtained of cup and disc. [1] The system can help ophthalmologist to perform early screening on diabetes patients. The proposed method used processes fundus image database obtained from Hospital. Together with other suitable retinal features extraction and classification methods, this segmentation method can form the basis of a fast and easy to use diagnostic support tool for diabetic retinopathy, which will give a huge advantage in terms of improved access to mass screening people for risk or presence of diabetes. 2.1 TYPES OF DISEASES: - Microaneurysms – The walls i.e. capillary walls are weakened which leads them to leakages. Haemorrhages – The capillaries that are weakened are ruptured which causes small dots or haemorrhages on the retinal layers. [2] Exudates – The proteins are leaked from retinal blood vessels. These look like yellow flakes. These are termed as hard exudates. These are the residues caused from leakage from damaged capillaries. The most common cause of hard exudates are DR [3]. Intraretinal Microvascular Abnormality (IrMA): -
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2261 Intraretinal microvascular abnormalities (or IrMAs) are the cause of dilation of blood vessels also known as capillaries within the retina.They appear as abnormal branching . [4] Fig 1: Healthy retina vs Diabetic Retinopathy affected eye. Fig 2: Healthy optic nerve vs optic nerve in eye with glaucoma 3. IMPLEMENTATION Firstly, Fundus camera will be used to take images of retina. Retina images contains optical disc, blood vessels. This project is focused on optic disc. So the size of optic disc will be cropped and saved for further processing. The cropped image of optic disc will be converted into binary image. Then the cup of the disc will be cropped from the retina image. Same processing techniques will be used for the cup. The threshold levels of the two cropped images will be different. The ratio of cup-to-disc ratio is important for determining the severity of the disease. The ratio values can be different for various reasons but the range is majorly fixed for normal, mild or heavily DR affected eyes. Fig 3: Handheld Fundus Camera  Taking the image of retina by using fundus camera which has microscope attached to high end camera, back of the eye is captured. Colour Image of Eye Effected by Glaucoma  Then this captured image is transferred to the computer and is stored to maintain the database of patient.  This retina image is colour image, we load this image into the application and then the optic disc is cropped manually. Colour Image of Optic Disc  We first detect the optic disc from the cropped image for which we make use of thresholding, i.e. we set threshold values for R, G and B.
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2262  Counting the black and the white pixels we get the area of the optic disc.  Similarly, we set different thresholding value for cup and get the area of the cup. Binary Image of Cup  By using this values of optic disc and cup, we find out the cup to disc ratio and depending on the value result is displayed, i.e. severity of the disease (HIGH, MEDIUM, NORMAL). 4.RESULT & CONCLUSION Original Cropped Optic Disc Cup Early detection of diabetic retinopathy is very important because it enables timely treatment that can ease the burden of the disease on the patients and their families by maintaining a sufficient quality of vision and preventing severe vision loss and blindness. Positive economic benefits can be achieved with early detection of diabetic retinopathy because patients can be more productive and can live without special medical care. Image processing and analysis algorithms are important because they enable development of automated systems for early detection of diabetic retinopathy. ACKNOWLEDGEMENT We would like to thank Prof. Priya Hankare for her support and guidance. Also we would like to thank Aditya Jyot Hospital for their help in providing us retina pictures and solving all our queries. REFERENCES [1] Ahmad Zikri Rozlan ,Hadzli Hashim ,Syed Farid Syed Adnan ,Chen Ai Hong ,Miswanudin Mahyudin. “A proposed diabetic retinopathy classification algorithm with statistical inference of exudates detection”. IEEE Xplore.Web.11 September.2014 [2] Dr. Olivia Scott, “Diabetic Retinopathy and Diabetic Eye Problems”. Web.20 January 2016. [3] Anonymous [4] Chris Kirkpatrick, “Intraretinal Microvascular Abnormality (IrMA)”.2013
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 2263 Purvi Kakasagar,Bachelor of Engineering from K.J. SOMAIYA INSTITUTE OF ENGINEERING AND INFORMATION TECHNOLOGY, Mumbai, Maharashtra, India Bhaviya Jagad, Bachelor of Engineering from K.J. SOMAIYA INSTITUTE OF ENGINEERING AND INFORMATION TECHNOLOGY, Mumbai, Maharashtra, India Dhwanil Barot, Bachelor of Engineering from K.J. SOMAIYA INSTITUTE OF ENGINEERING AND INFORMATION TECHNOLOGY, Mumbai, Maharashtra, India Omkar Joshi, Bachelor of Engineering from K.J. SOMAIYA INSTITUTE OF ENGINEERING AND INFORMATION TECHNOLOGY, Mumbai, Maharashtra, India