Nitrenes are nitrogen analogues of carbenes that contain no charge and are highly reactive and electrophilic. They exist in both singlet and triplet states, with the triplet state being more stable due to the presence of unpaired electrons. Nitrenes can be generated from acyl and alkyl azides, from sulphinylamine, or through insertion reactions. Important reactions involving nitrenes include the Beckmann rearrangement, Hofmann bromamide reaction, Curtius rearrangement, Lossen rearrangement, and Schmidt rearrangement.

1. NITRENE
BEBETO G NAIR
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1ST MSC ANALYTICAL CHEMISTRY
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2. Bebeto G Nitrenes 26/09/2019
Nitrenes
 Nitrogenous analogue of carbene
 Monovalent nitrogen species
 Contains no charge
 Electron deficient
 Electrophile
 Highly reactive
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3. Singlet
SP 2 Hybridisation
STRUCTURE OF NITRENE
Triplet
SP Hybridisation
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4. Stability
 Triplet > Singlet
 Presence of unpaired electrons in each orbital
 Only 33KJ/mol Energy
 Usually present in Ground state
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5. Generation
 From acyl and alkyl Azides
 From sulphinylamine
 Insertion reaction
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6. From acyl and alkyl azides
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7. From sulphinylamine
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8. Insertion reaction
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9. Important Name Reactions
 Beckmann Rearrangement Reaction
 Hoffman Bromamide Reaction
 Curtius Rearrangement Reaction
 Lossen Rearrangement Reaction
 Schmidt Rearrangement Reaction
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10. Beckmann Rearrangement Reaction
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- Ernst Otto Bechmann

11. Hofmann Bromamide Reaction
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- August Wilhelm Von Hofmann

12. Curtius rearrangement
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- Theodor Curtius

13. Lossen rearrangement
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- Wilhelm Lossen

14. Schmidt rearrangement
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- Karl Friedrich Schmidt

15. Bebeto G Nitrenes 26/09/2019
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