Nano medicine
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Cancer is a group of diseases involving abnormal cell growth that can spread to other parts of the body. Normally cells follow instructions from DNA to stay healthy, but when DNA is damaged or mutated, genes can instruct cells to divide uncontrollably and lead to cancer. Nanomedicine applies nanotechnology to prevent and treat disease by using nanoscale materials like biocompatible nanoparticles and nanorobots for diagnosis and drug delivery. Examples of cancer nanotechnology include injectable nanovectors like liposomes 1-100 nm in size that can deliver drug therapies specifically to breast cancer cells.
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Nanotechnology in medicine
This document discusses nanotechnology and its applications in medicine. It begins with the origins and definitions of nanotechnology. Some key approaches to nanofabrication include top-down and bottom-up methods. Nanocarriers such as liposomes, dendrimers, micelles, and nanoparticles can be used for targeted drug delivery. Nanotechnology has applications in regenerative medicine, disease diagnosis using nanomolecular diagnostics, and in-vitro diagnostics including nano biosensors and nanoarrays. Overall, nanomedicine holds promise for earlier disease detection and more targeted treatment approaches.
Nanobiotechnology lecture 1
introduction to Nanobiotechnology
what is nanotechnology
bionanotechnology
classical biotechnology industrial production using biological system
modern biotechnology from industrial processes to noval therapeutics
modern biotechnology immunological enzymatic and neucleic acid based technology
Dna based technology
self assembly and supramolecular chemistry
formation of ordered structure at nano scale
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From this presentation you can able to get some ideas on nanomedicine and about the future concepts of nanophysics.
Application of nanoparticals in drug delivery system
This document discusses nanoparticles and their applications in pharmaceuticals, with a focus on using gold nanoparticles (AuNPs) for cancer treatment. It defines nanoparticles and describes some common preparation methods. It then discusses several potential medical applications of nanoparticles, including using them as delivery systems for drugs, genes, and targeting cancer cells. Specifically for AuNPs, it covers their synthesis, properties, and how their surfaces can be functionalized. It describes how AuNPs may be useful for photothermal therapy, radiotherapy, and inhibiting angiogenesis for cancer treatment.
Nanomedicine
A brief presentation on Nanomedicine including history, diagnostics and therapeutics along with toxicology
Nanotechnology in medicine
Nanotechnology involves controlling and manipulating matter at the atomic and molecular scale from 1-100 nm. It allows the production of materials and devices with special properties not seen in bulk materials. Nanoparticles can be synthesized through various methods and engineered into different structures. Nanomedicine applies nanotechnology for health and medicine, enabling early disease detection and more targeted treatment through nano-sized materials and biosensors. In cancer treatment, nanoparticles can be engineered to target and deliver chemotherapeutics directly to tumor cells to minimize side effects.
Nanotechnology and its Application in Cancer Treatment
Nanotechnology
Nanomaterials
Nanostructures
Nanoparticles
Unexpected Optical Properties of Nanoparticles
Synthesis of Nanoparticles
Nanotechnology in Cancer Treatment
Role of Sulfur NPs in Cancer Treatment
Human Tumour Cell Lines Used in Research
Ehrlich ascites carcinoma (EAC)
Sulfur Nanoparticles Preparation
MTT Assay
Sulphorhodamine-B (SRB) Assay
Median lethal dose (LD 50)
Experimental design
FT-IR Characterization of Sulfur Nanoparticles
SEM Characterization of Sulfur Nanoparticles
EDS Characterization of Sulfur Nanoparticles
XRD Characterization of Sulfur Nanoparticles
Chemical Studies on Sulfur Nanoparticles In Vitro
Biochemical investigations
Conclusion
Applications of Nanoparticles in cancer treatment
Nanoshells
Nano X-Ray therapy
Drug Delivery by Nanoparticles
Use of Nanotechnology in Diagnosis and Treatment of Cancer
The document discusses how nanotechnology can be used for cancer diagnosis and treatment. It describes several nanoscale devices such as nanopores, nanotubes, quantum dots, dendrimers, liposomes, nanoshells, and nanorobots that can help detect genetic mutations associated with cancer, target delivery of drugs to cancer cells, and enable non-invasive cancer diagnosis and treatment with localized heat therapy. The manipulation of matter at the nanoscale allows more precise cancer detection and targeted therapy with fewer side effects than traditional approaches.
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Nanotechnology in medicine
This document discusses nanotechnology and its applications in medicine. It begins with the origins and definitions of nanotechnology. Some key approaches to nanofabrication include top-down and bottom-up methods. Nanocarriers such as liposomes, dendrimers, micelles, and nanoparticles can be used for targeted drug delivery. Nanotechnology has applications in regenerative medicine, disease diagnosis using nanomolecular diagnostics, and in-vitro diagnostics including nano biosensors and nanoarrays. Overall, nanomedicine holds promise for earlier disease detection and more targeted treatment approaches.
Nanobiotechnology lecture 1
introduction to Nanobiotechnology
what is nanotechnology
bionanotechnology
classical biotechnology industrial production using biological system
modern biotechnology from industrial processes to noval therapeutics
modern biotechnology immunological enzymatic and neucleic acid based technology
Dna based technology
self assembly and supramolecular chemistry
formation of ordered structure at nano scale
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From this presentation you can able to get some ideas on nanomedicine and about the future concepts of nanophysics.
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Nanotechnology in medicine
Nanotechnology involves controlling and manipulating matter at the atomic and molecular scale from 1-100 nm. It allows the production of materials and devices with special properties not seen in bulk materials. Nanoparticles can be synthesized through various methods and engineered into different structures. Nanomedicine applies nanotechnology for health and medicine, enabling early disease detection and more targeted treatment through nano-sized materials and biosensors. In cancer treatment, nanoparticles can be engineered to target and deliver chemotherapeutics directly to tumor cells to minimize side effects.
Nanotechnology and its Application in Cancer Treatment
Nanotechnology
Nanomaterials
Nanostructures
Nanoparticles
Unexpected Optical Properties of Nanoparticles
Synthesis of Nanoparticles
Nanotechnology in Cancer Treatment
Role of Sulfur NPs in Cancer Treatment
Human Tumour Cell Lines Used in Research
Ehrlich ascites carcinoma (EAC)
Sulfur Nanoparticles Preparation
MTT Assay
Sulphorhodamine-B (SRB) Assay
Median lethal dose (LD 50)
Experimental design
FT-IR Characterization of Sulfur Nanoparticles
SEM Characterization of Sulfur Nanoparticles
EDS Characterization of Sulfur Nanoparticles
XRD Characterization of Sulfur Nanoparticles
Chemical Studies on Sulfur Nanoparticles In Vitro
Biochemical investigations
Conclusion
Applications of Nanoparticles in cancer treatment
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Use of Nanotechnology in Diagnosis and Treatment of Cancer
The document discusses how nanotechnology can be used for cancer diagnosis and treatment. It describes several nanoscale devices such as nanopores, nanotubes, quantum dots, dendrimers, liposomes, nanoshells, and nanorobots that can help detect genetic mutations associated with cancer, target delivery of drugs to cancer cells, and enable non-invasive cancer diagnosis and treatment with localized heat therapy. The manipulation of matter at the nanoscale allows more precise cancer detection and targeted therapy with fewer side effects than traditional approaches.
NANO TECHNOLOGY IN DRUG DELIVERY SYSTEM
Nanotechnology uses structures sized 100 nm or smaller to develop drug delivery systems. Nanoparticles made from metals, lipids, polymers, or biological materials can encapsulate drugs and transport them in the body. Lipid nanoparticles like liposomes are biocompatible and protect drugs, allowing targeted delivery. Polymer nanoparticles like dendrimers and micelles also encapsulate drugs. Nanotechnology overcomes obstacles like the blood-brain barrier and can uniformly deliver drugs while sustaining their release and preventing degradation. Problems in drug delivery like poor oral availability are addressed through these nanoscale drug carriers.
NANOTECHNOLOGY, Applied For Treatment of Cancer
This document discusses using nanotechnology to treat cancer. It describes how nanodevices can be designed with sensors, motors, processors and other components to identify and destroy cancer cells. The nanodevices are injected and use scanning and mathematical computations to navigate the body and locate cancer cells. Once found, a gene reader identifies the cancer cells and RF energy is used to destroy them, while a bio-telemetry system monitors the nanodevice components.
NANOTECHNOLOGY IN TREATMENT OF CANCER
Nanotechnology involves engineering at the nanoscale (1-100 nanometers) and can be used in various fields including medicine. It has several applications for cancer treatment such as using nanoparticles, nanotubes, quantum dots, dendrimers, liposomes, nanoshells, silica nanoparticles, and nanorobots to more precisely deliver drugs to cancer cells, detect genetic mutations associated with cancer, and potentially diagnose and treat cancer. Nanoparticles in particular show promise for overcoming limitations of conventional cancer treatments like poor solubility, lack of targeting, and side effects by selectively targeting cancer cells and increasing drug localization.
Application of Gold nanoparticle in Phtothermal therapy of cancer
Gold nanoparticles are clusters of gold atoms up to 100nm in diameter that appear in various forms like spheres, rods, shells, cages, and stars. They are synthesized using chemical methods like the Turkevich, Brust, and Martin methods. Gold nanoparticles are analyzed using techniques like UV-Vis spectroscopy, TEM, and AFM. Due to their biocompatibility and stability, gold nanoparticles have medical applications in diagnosis, imaging, drug delivery, and photothermal therapy. In particular, gold nanoparticles can be used for photothermal therapy of cancer by converting light to heat to destroy tumor cells when irradiated with near infrared light.
Process design.cancer treatment using nanoparticles. ppt
Nanoparticles show promise for improving cancer detection and treatment. They are small enough to enter cells and interact with DNA and proteins. Quantum dots and nanoshells can be used to detect cancer signatures. Nanoshells coated with cancer-targeting molecules can selectively heat and destroy cancer cells when exposed to near-infrared light, protecting healthy cells. While challenges remain around toxicity and delivery, nanoparticles may enable cheaper, less toxic cancer therapies compared to chemotherapy and improve outcomes.
gold nanoshells
Gold nanoshells are being researched for use in photothermal cancer therapy. They are synthesized using methods such as coating silica-liposomes with gold. When exposed to near-infrared light, gold nanoshells heat up and destroy cancer cells in vitro. However, challenges remain in making them efficiently and safely for human use, which requires further research and FDA approval before clinical trials can begin.
Applications of nanobiotechnology in medicine
Nanomedicine uses nanotechnology to detect and treat diseases at the molecular level. Applications include using nanoparticles for targeted drug delivery to cancer sites, using nanobots to identify and destroy cancer cells, using photodynamic therapy to destroy tumors by activating nanoparticles with light, and developing nanorobots to remove plaque from arteries or break up kidney stones. Future applications may involve cell-sized robots to detect diseases by floating through the bloodstream or developing respirocytes as artificial red blood cells to deliver oxygen throughout the body.
Gold nanoparticles applications and challenges
Review paper on the applications and challenges of gold nanoparticles in medicine and dentistry.
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cancer treatment using nanotechnology
The main aim deals with the eradication of cancer cells by providing a steady, possible method of destroying and curing the cancer in an efficient and safe way so that healthy cells are not affected in any manner. This technology also focuses on a main idea that the patient is not affected by cancer again. The purpose of using the RF signal is to save normal cells.
Gold nanoparticles: strange properties and applications
View our gold nanoparticle range: http://www.innovabiosciences.com/gold-conjugation-kits.html
Gold nanoparticles exhibit extraordinary properties quite unlike those of the bulk metal. These properties can be exploited in a variety of assay applications, including lateral flow tests, microscopy, flow cytometry and FRET assays. There are also a number of therapeutic applications, especially in the field of cancer. This free and exciting webinar focuses on the following points:
1. Introduction to Gold
2. Unique properties of nanoparticles
3. Why does "40nm gold" never look the same from different suppliers?
4. Methods of attaching proteins and analytes to gold
5. Uses of nanoparticles in diagnostics
6. Uses of nanoparticles in therapeutics
Nanomedicine
Nanomedicine is an interdisciplinary field that uses nanotechnology for medical applications. It aims to diagnose, treat, and prevent disease at the molecular level using nano-scale tools. The document outlines the history of nanomedicine from Richard Feynman's 1959 talk introducing nanotechnology to current applications. Key applications discussed include drug delivery using nanoparticles like liposomes, imaging contrast agents, and miniaturized medical devices. Challenges also remain around potential toxicities of nanomaterials.
Protein based nanostructures for biomedical applications
Proteins are kind of natural molecules that show unique
functionalities and properties in biological materials and
manufacturing feld. Tere are numerous nanomaterials
which are derived from protein, albumin, and gelatin. Tese
nanoparticles have promising properties like biodegradability, nonantigenicity, metabolizable, surface modifer, greater
stability during in vivo during storage, and being relatively
easy to prepare and monitor the size of the particles.
These particles have the ability to attach covalently with
drug and ligand
Nanotech in pharmacy
Nanotechnology refers to technology conducted at the nanoscale from 1 to 100 nanometers. It has many applications in pharmaceutics including as drug delivery mechanisms, biosensors, and imaging tools. Nanotechnology uses nanomaterials like nanoparticles, nanotubes, dendrimers and nanostructures to target drugs intracellularly, help treat diseases like cancer and improve drug absorption. Current applications of nanotechnology in pharmaceutics include areas like nanomedicine, tissue engineering, biosensors and imaging.
Targeting oral cancer using gold nanoparticles
1. Done by: Dr. Mohamad Ghazi Kassem
2. What is Nanotechnology An engineered DNA strandtiny motor pRNA Semiconducting metal junction formed by two carbon nanotubes Nanotechnology is the creation of functional materials, devices and systems, through the understanding and control of matter at dimensions in the nanometer scale length (1-100 nm), where new functionalities and properties of matter are observed and harnessed for a broad range of applications.
3. What is Nanoscale Fullerenes C60 22 cm 12,756 Km 1.27 × 107 m 0.22 m 10 millions times smaller 0.7 nm 0.7 × 10-9 m 1 billion times smaller
4. What Are Gold Nanoparticles? • Gold nanoparticles (‘nanogold’) occur as clusters of gold atoms up to 100nm in diameter. Gold nanoparticle • Nanogold has unusual visible properties because the particles are small enough to scatter visible light. - in contrast, mass gold reflects light. 5nm gold clusters
5. • Gold nanoparticles appear yellow to deep red to in solution. - colour depends on size of nanoparticles • The distance between particles also affects colour - surface plasmon resonance is the term used by nanotechnologists to describe this effect.
6. Why Gold Nanoparticles Cancer is a difficult disease to treat, contain, and identify. There are many different ways for treating cancer such as surgery, chemotherapy, radiation and many others. These methods are effective if the cancer tumor is caught soon enough. However, these treatments are not effective enough because they do not only target the affected cells, they also affect healthy cells. But • Gold Nanoparticles are non toxic • With Gold Nanoparticles we can detecting cancer cells and even destroy them without affect healthy cells.
7. Mostafa A. El-Sayed Julius Brown Chair and Regents Professor; Director, Laser Dynamics Laboratory “Gold nanoparticles are very good at scattering and absorbing light,” said Mostafa El-Sayed, director of the Laser Dyanamics Laboratory and chemistry professor at Georgia Tech. “We wanted to see if we could harness that scattering property in a living cell to make cancer detection easier. So far, the results are extremely promising.”
8. Gold Nanoparticle Tumor Detection The common strategy to detect the tumor is the functionalization of the nanoparticle with an antibody specific to the tumor antigens, and then detect the nanoparticle by some spectroscopic technique B. Tumor photograph Imaging with gold nanoparticles as contrast agent
9. Many cancer cells have a protein, known as Epidermal Growth Factor Receptor (EFGR), all over their surface, while healthy cells typically do not express the protein as strongly. By conjugating, or binding, the gold nanoparticles to an antibody for EFGR, suitably named antiEFGR, researchers were able to get the nanoparticles to attach themselves to the cancer cells. Electrostatically + + + + - - - + + + - + -+ - - + + + + Covalently S S S S S S S S
10. Gold Nanoparticles Nanoshells
Nanomedicine (nanotechnology in medicine )
This document discusses the applications of nanotechnology in medicine. It begins by defining nanotechnology as dealing with structures between 1-100 nanometers in size, around the size of viruses. Nanomedicine aims to monitor, control and improve human biological systems at the molecular level using nanostructures. Some key applications discussed include nanodrug delivery systems, in vitro diagnostics using lab-on-a-chip devices, in vivo imaging and implants, nanopharmaceuticals using nanocarriers for targeted drug delivery, and regenerative medicine using stem cells and biomaterials at the nanoscale. The document examines the potential benefits and challenges of applying nanotechnology across various medical fields.
nanomedicine
This document discusses nanomedicine and its potential applications. Nanomedicine uses engineered nanodevices and nanostructures to monitor, repair, construct and control human biological systems at the molecular level. The goals of nanomedicine include improved diagnostics, treatment and prevention through a personalized single platform that integrates detection, diagnostics, treatment. Some potential applications discussed include using nanoparticles to deliver drugs precisely to tumor sites, detecting cancer at the molecular level, and developing multifunctional therapeutics. While nanomedicine is not fully realized yet, it could change medicine by making therapies more effective, economical and safe compared to current methods.
Nanomaterials in Drug Delivery
Nanomaterials are materials with at least one dimension between 1-100 nm that exhibit unique properties compared to larger materials. They have many applications including in drug delivery due to their high surface area and ability to reach difficult areas of the body smaller than cells. Nanoscale drug delivery systems include nanoparticles, liposomes, dendrimers, polymers, nanoshells, fullerenes, nanotubes, and quantum dots. Liposomes in particular are spherical vesicles consisting of an aqueous core surrounded by a lipid bilayer that can encapsulate both hydrophilic and hydrophobic drugs and provide benefits like controlled release and altered pharmacokinetics. The development of nano-carriers is improving drug therapy by enhancing efficiency and selectivity while reducing side effects
An Overview Of Nanotechnology In Medicine
Nanotechnology involves manipulating matter at the atomic or molecular scale, typically 100 nanometers or smaller. Richard Feynman first suggested the possibility of nanomachines in 1959. Albert Hibbs later suggested using nanomachines for medical purposes like surgery. Current applications of nanotechnology in medicine include more targeted drug delivery, cancer treatment using gold nanoparticles, microsurgery using nanoscale instruments, medical robotics, and tissue engineering. While nanomedicine holds promise, it also raises social, economic, ethical, and safety issues that warrant careful consideration and oversight to ensure its safe and equitable development and use.
DNA Nanotechnology: Concept and its Applications
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Nanobiotechnology BY Neelima Sharma,WCC CHENNAI,neelima.sharma60@gmail.com
Nanobiotechnology combines nanotechnology and biotechnology to create functional materials and devices at the nanoscale (1-100 nm) where new properties emerge. It allows for imaging and manipulation of biomolecules, development of biosensors, targeted drug delivery for cancer treatment, and regenerative medicine using biomimetic tissues. While offering promising applications, nanobiotechnology may also pose toxicity risks if nanoparticles are able to penetrate tissues and cells and cause biochemical damage.
Nanotechnology and Cancer 6.pdf
This document discusses how nanotechnology can be used for cancer diagnosis and treatment. It provides an overview of cancer, common diagnosis and treatment methods, and drawbacks. Then it introduces nanotechnology and how nanoparticles, nanotubes, and nanorobots can help detect cancer earlier and more precisely compared to traditional methods. Nanoparticles can also be used for targeted drug delivery to cancer cells to improve treatment effectiveness while reducing side effects.
Medical science using nano technology
Ultimate goal of nanomedicine is to integrate disease detection, diagnostics, treatment and prevention into a single personalized platform. Nanoparticles can be used for targeted drug delivery and detection of pathogens and cancer. For example, gold nanoparticles have been functionalized with oligonucleotides to detect specific RNA sequences through fluorescence. Nanoparticles less than the size of cancer cell pores can pass through tumor interstitial spaces, delivering therapeutic payloads directly inside tumors. While promising applications are under development, regulatory issues around safety, ethics, and artificial intelligence must be addressed for nanomedicine to realize its potential for widespread health improvements.
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This document discusses using nanotechnology to treat cancer. It describes how nanodevices can be designed with sensors, motors, processors and other components to identify and destroy cancer cells. The nanodevices are injected and use scanning and mathematical computations to navigate the body and locate cancer cells. Once found, a gene reader identifies the cancer cells and RF energy is used to destroy them, while a bio-telemetry system monitors the nanodevice components.
NANOTECHNOLOGY IN TREATMENT OF CANCER
Nanotechnology involves engineering at the nanoscale (1-100 nanometers) and can be used in various fields including medicine. It has several applications for cancer treatment such as using nanoparticles, nanotubes, quantum dots, dendrimers, liposomes, nanoshells, silica nanoparticles, and nanorobots to more precisely deliver drugs to cancer cells, detect genetic mutations associated with cancer, and potentially diagnose and treat cancer. Nanoparticles in particular show promise for overcoming limitations of conventional cancer treatments like poor solubility, lack of targeting, and side effects by selectively targeting cancer cells and increasing drug localization.
Application of Gold nanoparticle in Phtothermal therapy of cancer
Gold nanoparticles are clusters of gold atoms up to 100nm in diameter that appear in various forms like spheres, rods, shells, cages, and stars. They are synthesized using chemical methods like the Turkevich, Brust, and Martin methods. Gold nanoparticles are analyzed using techniques like UV-Vis spectroscopy, TEM, and AFM. Due to their biocompatibility and stability, gold nanoparticles have medical applications in diagnosis, imaging, drug delivery, and photothermal therapy. In particular, gold nanoparticles can be used for photothermal therapy of cancer by converting light to heat to destroy tumor cells when irradiated with near infrared light.
Process design.cancer treatment using nanoparticles. ppt
Nanoparticles show promise for improving cancer detection and treatment. They are small enough to enter cells and interact with DNA and proteins. Quantum dots and nanoshells can be used to detect cancer signatures. Nanoshells coated with cancer-targeting molecules can selectively heat and destroy cancer cells when exposed to near-infrared light, protecting healthy cells. While challenges remain around toxicity and delivery, nanoparticles may enable cheaper, less toxic cancer therapies compared to chemotherapy and improve outcomes.
gold nanoshells
Gold nanoshells are being researched for use in photothermal cancer therapy. They are synthesized using methods such as coating silica-liposomes with gold. When exposed to near-infrared light, gold nanoshells heat up and destroy cancer cells in vitro. However, challenges remain in making them efficiently and safely for human use, which requires further research and FDA approval before clinical trials can begin.
Applications of nanobiotechnology in medicine
Nanomedicine uses nanotechnology to detect and treat diseases at the molecular level. Applications include using nanoparticles for targeted drug delivery to cancer sites, using nanobots to identify and destroy cancer cells, using photodynamic therapy to destroy tumors by activating nanoparticles with light, and developing nanorobots to remove plaque from arteries or break up kidney stones. Future applications may involve cell-sized robots to detect diseases by floating through the bloodstream or developing respirocytes as artificial red blood cells to deliver oxygen throughout the body.
Gold nanoparticles applications and challenges
Review paper on the applications and challenges of gold nanoparticles in medicine and dentistry.
Gold nanoparticles is a game-changer in delivering patient care. Its versatility can be put to use in diagnosis, imaging and treatment of various conditions. It relatively recent innovation although gold is a metal that has had a lot of meaning in human civilisation.With a lot of potential left unexplored one has to what and watch the miracles this breakthrough has in store for medical science.
cancer treatment using nanotechnology
The main aim deals with the eradication of cancer cells by providing a steady, possible method of destroying and curing the cancer in an efficient and safe way so that healthy cells are not affected in any manner. This technology also focuses on a main idea that the patient is not affected by cancer again. The purpose of using the RF signal is to save normal cells.
Gold nanoparticles: strange properties and applications
View our gold nanoparticle range: http://www.innovabiosciences.com/gold-conjugation-kits.html
Gold nanoparticles exhibit extraordinary properties quite unlike those of the bulk metal. These properties can be exploited in a variety of assay applications, including lateral flow tests, microscopy, flow cytometry and FRET assays. There are also a number of therapeutic applications, especially in the field of cancer. This free and exciting webinar focuses on the following points:
1. Introduction to Gold
2. Unique properties of nanoparticles
3. Why does "40nm gold" never look the same from different suppliers?
4. Methods of attaching proteins and analytes to gold
5. Uses of nanoparticles in diagnostics
6. Uses of nanoparticles in therapeutics
Nanomedicine
Nanomedicine is an interdisciplinary field that uses nanotechnology for medical applications. It aims to diagnose, treat, and prevent disease at the molecular level using nano-scale tools. The document outlines the history of nanomedicine from Richard Feynman's 1959 talk introducing nanotechnology to current applications. Key applications discussed include drug delivery using nanoparticles like liposomes, imaging contrast agents, and miniaturized medical devices. Challenges also remain around potential toxicities of nanomaterials.
Protein based nanostructures for biomedical applications
Proteins are kind of natural molecules that show unique
functionalities and properties in biological materials and
manufacturing feld. Tere are numerous nanomaterials
which are derived from protein, albumin, and gelatin. Tese
nanoparticles have promising properties like biodegradability, nonantigenicity, metabolizable, surface modifer, greater
stability during in vivo during storage, and being relatively
easy to prepare and monitor the size of the particles.
These particles have the ability to attach covalently with
drug and ligand
Nanotech in pharmacy
Nanotechnology refers to technology conducted at the nanoscale from 1 to 100 nanometers. It has many applications in pharmaceutics including as drug delivery mechanisms, biosensors, and imaging tools. Nanotechnology uses nanomaterials like nanoparticles, nanotubes, dendrimers and nanostructures to target drugs intracellularly, help treat diseases like cancer and improve drug absorption. Current applications of nanotechnology in pharmaceutics include areas like nanomedicine, tissue engineering, biosensors and imaging.
Targeting oral cancer using gold nanoparticles
1. Done by: Dr. Mohamad Ghazi Kassem
2. What is Nanotechnology An engineered DNA strandtiny motor pRNA Semiconducting metal junction formed by two carbon nanotubes Nanotechnology is the creation of functional materials, devices and systems, through the understanding and control of matter at dimensions in the nanometer scale length (1-100 nm), where new functionalities and properties of matter are observed and harnessed for a broad range of applications.
3. What is Nanoscale Fullerenes C60 22 cm 12,756 Km 1.27 × 107 m 0.22 m 10 millions times smaller 0.7 nm 0.7 × 10-9 m 1 billion times smaller
4. What Are Gold Nanoparticles? • Gold nanoparticles (‘nanogold’) occur as clusters of gold atoms up to 100nm in diameter. Gold nanoparticle • Nanogold has unusual visible properties because the particles are small enough to scatter visible light. - in contrast, mass gold reflects light. 5nm gold clusters
5. • Gold nanoparticles appear yellow to deep red to in solution. - colour depends on size of nanoparticles • The distance between particles also affects colour - surface plasmon resonance is the term used by nanotechnologists to describe this effect.
6. Why Gold Nanoparticles Cancer is a difficult disease to treat, contain, and identify. There are many different ways for treating cancer such as surgery, chemotherapy, radiation and many others. These methods are effective if the cancer tumor is caught soon enough. However, these treatments are not effective enough because they do not only target the affected cells, they also affect healthy cells. But • Gold Nanoparticles are non toxic • With Gold Nanoparticles we can detecting cancer cells and even destroy them without affect healthy cells.
7. Mostafa A. El-Sayed Julius Brown Chair and Regents Professor; Director, Laser Dynamics Laboratory “Gold nanoparticles are very good at scattering and absorbing light,” said Mostafa El-Sayed, director of the Laser Dyanamics Laboratory and chemistry professor at Georgia Tech. “We wanted to see if we could harness that scattering property in a living cell to make cancer detection easier. So far, the results are extremely promising.”
8. Gold Nanoparticle Tumor Detection The common strategy to detect the tumor is the functionalization of the nanoparticle with an antibody specific to the tumor antigens, and then detect the nanoparticle by some spectroscopic technique B. Tumor photograph Imaging with gold nanoparticles as contrast agent
9. Many cancer cells have a protein, known as Epidermal Growth Factor Receptor (EFGR), all over their surface, while healthy cells typically do not express the protein as strongly. By conjugating, or binding, the gold nanoparticles to an antibody for EFGR, suitably named antiEFGR, researchers were able to get the nanoparticles to attach themselves to the cancer cells. Electrostatically + + + + - - - + + + - + -+ - - + + + + Covalently S S S S S S S S
10. Gold Nanoparticles Nanoshells
Nanomedicine (nanotechnology in medicine )
This document discusses the applications of nanotechnology in medicine. It begins by defining nanotechnology as dealing with structures between 1-100 nanometers in size, around the size of viruses. Nanomedicine aims to monitor, control and improve human biological systems at the molecular level using nanostructures. Some key applications discussed include nanodrug delivery systems, in vitro diagnostics using lab-on-a-chip devices, in vivo imaging and implants, nanopharmaceuticals using nanocarriers for targeted drug delivery, and regenerative medicine using stem cells and biomaterials at the nanoscale. The document examines the potential benefits and challenges of applying nanotechnology across various medical fields.
nanomedicine
This document discusses nanomedicine and its potential applications. Nanomedicine uses engineered nanodevices and nanostructures to monitor, repair, construct and control human biological systems at the molecular level. The goals of nanomedicine include improved diagnostics, treatment and prevention through a personalized single platform that integrates detection, diagnostics, treatment. Some potential applications discussed include using nanoparticles to deliver drugs precisely to tumor sites, detecting cancer at the molecular level, and developing multifunctional therapeutics. While nanomedicine is not fully realized yet, it could change medicine by making therapies more effective, economical and safe compared to current methods.
Nanomaterials in Drug Delivery
Nanomaterials are materials with at least one dimension between 1-100 nm that exhibit unique properties compared to larger materials. They have many applications including in drug delivery due to their high surface area and ability to reach difficult areas of the body smaller than cells. Nanoscale drug delivery systems include nanoparticles, liposomes, dendrimers, polymers, nanoshells, fullerenes, nanotubes, and quantum dots. Liposomes in particular are spherical vesicles consisting of an aqueous core surrounded by a lipid bilayer that can encapsulate both hydrophilic and hydrophobic drugs and provide benefits like controlled release and altered pharmacokinetics. The development of nano-carriers is improving drug therapy by enhancing efficiency and selectivity while reducing side effects
An Overview Of Nanotechnology In Medicine
Nanotechnology involves manipulating matter at the atomic or molecular scale, typically 100 nanometers or smaller. Richard Feynman first suggested the possibility of nanomachines in 1959. Albert Hibbs later suggested using nanomachines for medical purposes like surgery. Current applications of nanotechnology in medicine include more targeted drug delivery, cancer treatment using gold nanoparticles, microsurgery using nanoscale instruments, medical robotics, and tissue engineering. While nanomedicine holds promise, it also raises social, economic, ethical, and safety issues that warrant careful consideration and oversight to ensure its safe and equitable development and use.
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Nanobiotechnology BY Neelima Sharma,WCC CHENNAI,neelima.sharma60@gmail.com
Nanobiotechnology combines nanotechnology and biotechnology to create functional materials and devices at the nanoscale (1-100 nm) where new properties emerge. It allows for imaging and manipulation of biomolecules, development of biosensors, targeted drug delivery for cancer treatment, and regenerative medicine using biomimetic tissues. While offering promising applications, nanobiotechnology may also pose toxicity risks if nanoparticles are able to penetrate tissues and cells and cause biochemical damage.
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Application of Gold nanoparticle in Phtothermal therapy of cancer
Application of Gold nanoparticle in Phtothermal therapy of cancer
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Process design.cancer treatment using nanoparticles. ppt
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Protein based nanostructures for biomedical applications
Protein based nanostructures for biomedical applications
Nanobiotechnology BY Neelima Sharma,WCC CHENNAI,neelima.sharma60@gmail.com
Nanobiotechnology BY Neelima Sharma,WCC CHENNAI,neelima.sharma60@gmail.com
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This document discusses how nanotechnology can be used for cancer diagnosis and treatment. It provides an overview of cancer, common diagnosis and treatment methods, and drawbacks. Then it introduces nanotechnology and how nanoparticles, nanotubes, and nanorobots can help detect cancer earlier and more precisely compared to traditional methods. Nanoparticles can also be used for targeted drug delivery to cancer cells to improve treatment effectiveness while reducing side effects.
Medical science using nano technology
Ultimate goal of nanomedicine is to integrate disease detection, diagnostics, treatment and prevention into a single personalized platform. Nanoparticles can be used for targeted drug delivery and detection of pathogens and cancer. For example, gold nanoparticles have been functionalized with oligonucleotides to detect specific RNA sequences through fluorescence. Nanoparticles less than the size of cancer cell pores can pass through tumor interstitial spaces, delivering therapeutic payloads directly inside tumors. While promising applications are under development, regulatory issues around safety, ethics, and artificial intelligence must be addressed for nanomedicine to realize its potential for widespread health improvements.
Nanotechnology in cancer therapy
This presentation is related to cancer treatment and involvement of the nanotechnology in cancer research. This has different nanotechnology-related delivery information.
Nano technology for medicine
This document discusses the field of nanomedicine and its applications. Nanomedicine uses nano-sized materials and devices in medicine to diagnose, treat, and prevent diseases. It has several advantages like enabling targeted drug delivery, reducing side effects, and allowing for easier detection of diseases. However, there are also limitations regarding toxicity, developing nanomaterials with advanced properties requires expertise, and only a few nanoparticle formulations have been approved for clinical use. The document outlines areas of nanomedicine like drug delivery, medical nanorobots, gene delivery, and cancer detection. It suggests that expanding nanomedicine to detect and treat virus-caused diseases could be useful.
cancer treatment using nanotechnology by RAMYA G
This document discusses using nanotechnology for cancer treatment. It describes how nanoparticles can target cancer cells due to their rapid growth and nutrient intake. Experiments showed that mice with human prostate tumors treated with nanoparticles targeted to cancer cells had a 100% survival rate, compared to 57% for untargeted nanoparticles and 14% for chemotherapy alone. Challenges include developing biocompatible nanoparticles that can target cancer cells without side effects. Future applications could include human trials in the next few years and managing cancer as a chronic disease in 15-20 years.
Nanotechnoloy in Cancer.pptx
The document discusses the applications of nanotechnology in cancer diagnosis and treatment. It describes how nanoparticles can be engineered for passive and active tumor targeting via the enhanced permeability and retention effect or by attaching targeting ligands. Various nanocarriers including dendrimers, liposomes, quantum dots, iron oxide nanoparticles, and multifunctional nanoparticles are summarized. The document also discusses how nanotechnology enables targeted delivery of drugs, genes, photosensitizers and hyperthermia for cancer therapy. Nanoparticles can also be used as contrast agents for improved cancer imaging and detection. While nanotechnology has made progress in oncology, more clinical studies are still needed to prove the efficacy and safety of nanomedicine applications for cancer patients.
Nanotechnology
nanotechnology is one of the most advance technology
biotechnology techniques for treatment of different diseases
Nano materials for cancer therapy.pptx (seminar).pptx by me
Nano materials show promise for more targeted cancer treatments with fewer side effects. Nanoparticles can be programmed to selectively destroy cancer cells without harming healthy cells, allowing patients to recover more quickly. Various nano structures under research include gold-coated silica nano shells for targeted drug delivery, dendrimers that can combine imaging, targeting and drug functions, and superparamagnetic nanoparticles for magnetic resonance imaging and targeting via magnetic fields. Applications include using quantum dots for optical detection, carbon nanotubes for biomarker detection, and nano sponges for sustained drug release at tumor sites. Overall, nano technologies may enable more effective cancer diagnostics and treatments with less toxicity.
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The document discusses two discoveries that could lead to better cancer treatments and ways to destroy viruses. Specifically, it summarizes that identifying vulnerable DNA regions that are prone to damage could allow treatments to be targeted. It also discusses how cells' DNA repair machinery uses enzymes to remove stray nucleotides added by viruses, which could stop the replication of viruses like HIV if enhanced. Overall, the document outlines potential medical applications of these findings, like developing effective treatments for diseases currently lacking cures.applicationsofnanobiotechnologyinmedicine-200421050140.pdf
Nanobiotechnology and nanomedicine allow for targeted drug delivery and treatment at the cellular level using nanoparticles and nanorobots. Potential applications include using nanoparticles to deliver chemotherapy directly to tumors, using photodynamic therapy to destroy cancer cells with light, and developing nanorobots to remove plaque from arteries or break up kidney stones with lasers. Future possibilities involve cell-sized robots that can detect disease while circulating in the bloodstream and respirocytes that act as artificial red blood cells to deliver oxygen throughout the body.
NANO TECHNOLOGY
Nanotechnology has potential applications for cancer detection and treatment. It involves engineering systems at the molecular scale, smaller than 100 nanometers. This small size allows nanodevices to enter cells and detect diseases. Researchers are developing nanoparticles linked to antibodies that can seek out and destroy cancer cells through heat ablation. Nanotechnology may improve cancer treatment by targeting cancer cells directly without harming healthy cells. While it offers advantages like increased detection and more effective therapies, challenges remain around toxicity, targeting specificity, and moving applications from research to human trials. Overall, nanotechnology shows promise for transforming cancer treatment if these challenges can be addressed.
Gene therapy
Gene therapy is the insertion of genes into a patient's cells to treat disease. It works by replacing a defective gene with a functional one. The basic process involves identifying the faulty gene causing a condition, delivering a working version of the gene to the affected cells using a viral vector, and having the gene expressed within the target cells. Recent advances include the first FDA-approved gene therapy for an inherited disease in 2017 and CAR-T therapies using genetically engineered immune cells to treat some cancers. While still early in development, gene therapy has shown success in clinical trials for diseases like cystic fibrosis and is a promising field of research.
Samikshya Patel.pptx
fdghtrjvvbcdfzh vcbvsghttbvcvxcsdfrghtngfbvsdvbgnnhgndvbhvjifhuidhbvuuhlknbvhjbfxhlvnljlksbhulidknvlnchlxch.nj.ncjo;jvoihuisjlkjjlkjhv;ijlkvncvjnkjlh kjn jkljnjklmoijbuilhdgoiiovviso9isdujfiiuhihuigifdlhuifdhgriyjdupuivhkansfWastewater Treatment Process: Definition, Procedure & Steps
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Wastewater treatment is the procedure used for the purpose of removing contaminants from wastewater. It further involves the process of converting water into an effluent that can be recycled into the water cycle. Once returned to the water cycle, the effluent is in an acceptable environmental impact or is reused for a variety of purposes.
Wastewater treatment procedure involves the process of treating wastewater appropriately. There are different ways to treat wastewater in a wastewater treatment plant. The treatment plant for domestic wastewater is referred to as a sewage treatment plant. The industrial wastewater treatment process takes place either in a separate industrial wastewater treatment plant or in a sewage treatment plant. Agricultural wastewater treatment plants and leachate treatment plants are two other types of wastewater treatment plants. To know more about the wastewater treatment plant process, read the article below.
Learn Informative Blog
Embibe offers a range of study materials for students in CBSE board. These study materials include previous year question papers, NCERT books and solution sets. A team of experts from Embibe prepares the solution sets that will help the students understand the correct approach to be followed to answer the questions in the solution set correctly. All these study materials are avialable in PDF format and can be downloaded for free.
Wastewater Treatment: Details
A wastewater treatment plant is a facility that treats wastewater, making it considerably cleaner and safer to be released into water bodies. A wastewater treatment plant is a place where wastewater from homes and other buildings is collected and processed. WWTP is an abbreviation for Waste-Water Treatment Plant. A wastewater treatment plant is also referred to as a sewage treatment plant. A modern wastewater treatment plant treats wastewater or sewage through a series of physical, chemical, and biological processes until it becomes fit to be discharged into the environment.
Wastewater Treatment Plant
Wastewater Treatment: Process
Treatment of wastewater involves physical, chemical, and biological processes, which remove physical, chemical and biological matter that contaminates the wastewater. The sewage treatment plant treats all of the collected sewage water. Before wastewater is discharged into water reservoirs, it goes through the following processes.
Wastewater Treatment: Design / Diagram
Wastewater Treatment Plant Design / Diagram
I. Screening
The wastewater that enters the sewage treatment plant is first filtered through bar screens, a process known as screening. The bar screen separates large trash objects from the wastewater, such ab
advance treatments in oral cancer
This document discusses recent advancements in oral cancer treatment, including photodynamic therapy, intralesional chemotherapy, intra-arterial chemotherapy, intensity modulated radiation therapy, immunotherapy, gene therapy, and cancer vaccines. Photodynamic therapy involves injecting a photosensitizer that is activated by light to kill tumor cells. Intralesional chemotherapy directly injects drugs into tumors while intra-arterial chemotherapy injects drugs into arteries feeding tumors. Intensity modulated radiation therapy and immunotherapy such as gene therapy and cancer vaccines are also discussed as promising new oral cancer treatments.
Cancer chemoprevention
Cancer chemoprevention uses natural or laboratory-made substances to prevent cancer from developing. It is typically used by people at higher risk of cancer, such as those with a family history or previous cancer. Some chemopreventive agents studied include tamoxifen, raloxifene, aspirin and other NSAIDs. While chemoprevention may lower cancer risk, it also carries risks of side effects that must be weighed against the individual's cancer risk. Clinical trials test chemopreventive agents' safety and efficacy in delaying or preventing cancer. Targeted drug delivery seeks to concentrate medication in tissues of interest while reducing side effects by specifically targeting cancer cells over normal cells. Strategies include passive,
Nanoparticles in cancer diagnosis
This document discusses the use of nanotechnology for cancer diagnosis and therapy. It begins by defining cancer and tumors, and then introduces nanotechnology and its applications in medicine including drug delivery, imaging, and cancer treatment. Specific nanoparticles discussed for cancer diagnosis include gold nanoparticles, bismuth sulfide nanoparticles, and iron oxide nanoparticles which can be used for computed tomography, magnetic resonance imaging, and ultrasound imaging, respectively. The document also discusses various nanoparticle-based approaches for detecting different types of cancer like bladder and breast cancer. In general, the document outlines how nanotechnology enables more precise cancer diagnosis and targeted therapy.
Nanocarrier based strategies for eye cancer management and
This document discusses nanocarrier based strategies for eye cancer management and treatment. It begins by defining eye cancer and its common types, then discusses various nanocarriers that can be used for detection and treatment of eye cancer like quantum dots, carbon nanotubes, liposomes, dendrimers, gold nanoparticles, and nanoemulsions. The nanocarriers provide benefits like targeted delivery, bypassing biological barriers, and reduced toxicity compared to traditional methods. While nanocarriers provide advantages for drug loading and biocompatibility, they also have challenges with stability, drug release kinetics, and safety that require further research.
Nanomedicine
The document discusses the field of nanomedicine, which uses nanotechnology and medicine to develop novel therapies and improve existing treatments. It describes how atoms and molecules are manipulated at the nanoscale to interact with human cells. Examples of nanomedicine applications provided include quantum dots to detect and locate cancer cells, nanoparticles to deliver chemotherapy drugs directly to cancer cells, and nanotubes to identify DNA changes associated with cancer. The document outlines the advantages of nanomedicine in more precise targeting and delivery of drugs while reducing side effects, and the potential it holds to transform medicine.
Cancer vaccines
A cancer vaccine is a vaccine, that either treats existing cancer or prevents development of a cancer. Vaccines that treat existing cancer are known as therapeutic cancer vaccines.
Cancer vaccines
Cancer vaccines aim to teach the immune system to recognize and destroy cancer cells. There are several types of cancer vaccines being studied including dendritic cell vaccines, antigen vaccines, anti-idiotype vaccines, DNA vaccines, and tumor cell vaccines. These vaccines target various cancers like prostate, melanoma, breast, lung, colorectal, leukemia, kidney and more. If successful, cancer vaccines could open up a new approach in fighting cancer by boosting the body's natural defenses.
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One organism can be located on the surface of another organism as an ectobiont or located within another organism as endobiont.
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Nano medicine
- 2. Cancer •Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
- 3. Cancer Growth • Normally, our cells follow these instructions and we stay healthy. • But when there is a change in our DNA or damage to it, a Gene can mutate. Mutated genes don’t work properly because the instructions in their DNA get mixed up. This can cause cells that should be resting to divide and grow out of control, which can lead to cancer.
- 6. Nano Medicine • Nanomedicine is a branch of medicine that applies the knowledge and tools of nanotechnology to the prevention and treatment of disease. • Nanomedicine involves the use of nanoscale materials, such as biocompatible nanoparticles and nanorobots, for diagnosis,
- 9. What is cancer nanotechnology? Formal definitions of nanotechnological devices typically feature the requirements that the device itself or its essential components be man-made, and in the 1–1,00 nm range in at least one dimension. Cancer-related examples of nano-technologies include injectable drugdelivery NANOVECTORS such as LIPOSOMES for the therapy of breast cancer.7
- 14. Nanovectors • Nanovectors are a type of targeted delivery vehicle that transports nanoscale material. • Eg : antibody-targeted nanoparticles, such as conjugated liposomes