This document discusses the chemistry of morphine. It begins by defining morphine as a natural opium alkaloid and describing the composition of opium. It then classifies opium alkaloids and describes the isolation and structure elucidation of morphine. The document outlines morphine's chemical constitution and structure-activity relationship. It explains how analgesic activity can be increased or decreased by modifying morphine's structure. Finally, it lists some common uses of morphine and codeine.