Meningitis
•Download as PPTX, PDF•
1 like•38 views
The document provides an overview of meningitis, including: 1) Meningitis is a serious inflammation of the meninges that protects the brain and spinal cord. It can be caused by bacteria, viruses, fungi or other factors. 2) Symptoms include fever, headache, vomiting, sensitivity to light, and stiff neck. Left untreated, meningitis can cause brain damage or death. 3) Diagnosis involves spinal fluid tests. Treatment focuses on antibiotics, antivirals or antifungals depending on the cause. Early diagnosis and treatment are important to prevent long term effects.
Report
Share
Report
Share
Recommended
Meningitis
Meningitis is an infection of the meninges, the membranes covering the brain and spinal cord. It used to occur mainly in infants but a vaccine has reduced infant cases, so it now occurs primarily in adults. Viral meningitis is usually less severe and people typically recover fully, while bacterial meningitis can cause more serious complications like seizures, increased intracranial pressure, and residual neurological deficits if not treated promptly.
Bacterial & Viral Meningitis
Meningitis is an inflammation of the membranes covering the brain and spinal cord caused by bacterial or viral infections. The two most common types of bacterial meningitis are caused by Neisseria meningitidis (meningococcal meningitis) and Streptococcus pneumoniae (pneumococcal meningitis). Viruses from the enterovirus group are the most common cause of viral meningitis. Symptoms of meningitis include fever, headache, stiff neck, and sensitivity to light. While bacterial meningitis requires intravenous antibiotics, viral meningitis is usually treated with supportive care. Handwashing is the best way to prevent transmission between people through contact with nose and throat secretions.
Meningitis
PREPARED BY: MUHAMMAD ARIFF B. MAHDZUB
BACHELOR MEDICINE AND SURGERY (MBBS)
UNIVERSITY COLLEGE SHAHPUTRA, KUANTAN
bacterial meningitis
Bacterial meningitis is a serious infection of the membranes surrounding the brain and spinal cord. It is usually caused by bacteria such as Streptococcus pneumoniae or Neisseria meningitidis. Symptoms include sudden onset of fever, headache, and neck stiffness. Without prompt treatment, bacterial meningitis can cause death or permanent disability. Diagnosis involves examination of cerebrospinal fluid obtained through lumbar puncture. Empirical antibiotic therapy with drugs such as ceftriaxone and vancomycin is started immediately while diagnostic tests are pending. Vaccination is the most effective way to prevent certain types of bacterial meningitis.
Meningitis
Meningitis is an inflammation of the meninges, the protective membranes covering the brain and spinal cord. It is usually caused by microorganisms like bacteria and viruses spreading into the cerebrospinal fluid through the blood. The main types are bacterial, viral, fungal, parasitic, and non-infectious meningitis. Bacterial meningitis causes vary by age group, with newborns commonly experiencing Group B Streptococcus and older adults experiencing Streptococcus pneumoniae and Neisseria meningitidis.
Meningitis by lupote philip
Meningitis is an inflammation of the meninges that cover the brain and spinal cord. It is most commonly caused by bacteria, viruses, and fungi. The document discusses the various causes of meningitis including the typical bacteria that cause bacterial meningitis. It also outlines the signs and symptoms, methods of diagnosis including lumbar puncture, and treatment approaches which involve antibiotics for bacterial meningitis and antivirals for viral meningitis. Nursing care aims to maintain a clear airway, prevent complications, and maintain good nutrition.
Bacterial meningitis - Etiology, pathogenesis, Clinical features, Investigati...
Bacterial meningitis - Etiology, pathogenesis, Clinical features, Investigati...Chetan Ganteppanavar
Bacterial meningitis - Etiology, pathogenesis, Clinical features, Investigation, Treatment and OutcomeComplications of meningitis in children
Complications from meningitis can arise from the spread of infection or the healing process. Infection can spread to areas like the brain ventricles, subdural spaces, veins and sinuses, and bloodstream, potentially causing issues like ependymitis, thrombophlebitis, and metastatic infections. During healing, complications include arachnoid fibrosis which can lead to hydrocephalus, cranial nerve compression causing palsies, and obliterative endarteritis resulting in brain ischemia or infarcts. While viral meningitis complications are rare, bacterial meningitis poses greater risks like subdural effusion and neurological sequelae such as deafness, blindness, seizures, and mental retardation
Recommended
Meningitis
Meningitis is an infection of the meninges, the membranes covering the brain and spinal cord. It used to occur mainly in infants but a vaccine has reduced infant cases, so it now occurs primarily in adults. Viral meningitis is usually less severe and people typically recover fully, while bacterial meningitis can cause more serious complications like seizures, increased intracranial pressure, and residual neurological deficits if not treated promptly.
Bacterial & Viral Meningitis
Meningitis is an inflammation of the membranes covering the brain and spinal cord caused by bacterial or viral infections. The two most common types of bacterial meningitis are caused by Neisseria meningitidis (meningococcal meningitis) and Streptococcus pneumoniae (pneumococcal meningitis). Viruses from the enterovirus group are the most common cause of viral meningitis. Symptoms of meningitis include fever, headache, stiff neck, and sensitivity to light. While bacterial meningitis requires intravenous antibiotics, viral meningitis is usually treated with supportive care. Handwashing is the best way to prevent transmission between people through contact with nose and throat secretions.
Meningitis
PREPARED BY: MUHAMMAD ARIFF B. MAHDZUB
BACHELOR MEDICINE AND SURGERY (MBBS)
UNIVERSITY COLLEGE SHAHPUTRA, KUANTAN
bacterial meningitis
Bacterial meningitis is a serious infection of the membranes surrounding the brain and spinal cord. It is usually caused by bacteria such as Streptococcus pneumoniae or Neisseria meningitidis. Symptoms include sudden onset of fever, headache, and neck stiffness. Without prompt treatment, bacterial meningitis can cause death or permanent disability. Diagnosis involves examination of cerebrospinal fluid obtained through lumbar puncture. Empirical antibiotic therapy with drugs such as ceftriaxone and vancomycin is started immediately while diagnostic tests are pending. Vaccination is the most effective way to prevent certain types of bacterial meningitis.
Meningitis
Meningitis is an inflammation of the meninges, the protective membranes covering the brain and spinal cord. It is usually caused by microorganisms like bacteria and viruses spreading into the cerebrospinal fluid through the blood. The main types are bacterial, viral, fungal, parasitic, and non-infectious meningitis. Bacterial meningitis causes vary by age group, with newborns commonly experiencing Group B Streptococcus and older adults experiencing Streptococcus pneumoniae and Neisseria meningitidis.
Meningitis by lupote philip
Meningitis is an inflammation of the meninges that cover the brain and spinal cord. It is most commonly caused by bacteria, viruses, and fungi. The document discusses the various causes of meningitis including the typical bacteria that cause bacterial meningitis. It also outlines the signs and symptoms, methods of diagnosis including lumbar puncture, and treatment approaches which involve antibiotics for bacterial meningitis and antivirals for viral meningitis. Nursing care aims to maintain a clear airway, prevent complications, and maintain good nutrition.
Bacterial meningitis - Etiology, pathogenesis, Clinical features, Investigati...
Bacterial meningitis - Etiology, pathogenesis, Clinical features, Investigati...Chetan Ganteppanavar
Bacterial meningitis - Etiology, pathogenesis, Clinical features, Investigation, Treatment and OutcomeComplications of meningitis in children
Complications from meningitis can arise from the spread of infection or the healing process. Infection can spread to areas like the brain ventricles, subdural spaces, veins and sinuses, and bloodstream, potentially causing issues like ependymitis, thrombophlebitis, and metastatic infections. During healing, complications include arachnoid fibrosis which can lead to hydrocephalus, cranial nerve compression causing palsies, and obliterative endarteritis resulting in brain ischemia or infarcts. While viral meningitis complications are rare, bacterial meningitis poses greater risks like subdural effusion and neurological sequelae such as deafness, blindness, seizures, and mental retardation
Meningitis jose ramonjoyanes-jorgegonzalez
Meningitis is an infectious disease that causes inflammation of the membranes surrounding the brain and spinal cord. It can be caused by viruses or bacteria found in the nose and throat. Common symptoms include high fever, severe headache, stiff neck, vomiting, and confusion. While most cases are mild and caused by viruses, bacterial meningitis can be life-threatening if not treated promptly with antibiotics. Vaccines exist to help prevent some common types of bacterial meningitis. Diagnosis involves examining cerebrospinal fluid through a lumbar puncture procedure.
Meningitis
Meningitis is an inflammation of the protective membranes (meninges) surrounding the brain and spinal cord. It is usually caused by a viral or bacterial infection. The meninges have three layers (dura mater, arachnoid mater, and pia mater) that are separated by fluid-filled spaces. Meningitis is a medical emergency because it can be life-threatening. It most commonly affects children and young adults. Bacterial meningitis is usually preceded by a mild respiratory infection that allows bacteria to enter the bloodstream and meninges. Diagnosis involves examination of cerebrospinal fluid obtained via lumbar puncture for signs of infection.
Meningitis
Meningitis is an inflammation of the protective membranes covering the brain and spinal cord caused most commonly by viral and bacterial infections. It can be life-threatening if not treated properly. The symptoms include headache, neck stiffness, fever, and sensitivity to light. A lumbar puncture of the cerebrospinal fluid is required for diagnosis. Treatment involves antibiotics for bacterial meningitis and supportive care, while prevention focuses on vaccination programs.
Cns infections Lecture
The document outlines key information about infections of the central nervous system, including various bacterial, viral, protozoal and fungal infections that can cause meningitis or encephalitis. It discusses the typical presentation, symptoms, diagnostic evaluation and treatment of different types of meningitis and how they vary depending on the causative pathogen and patient age.
Meningitis
This document discusses different types of meningitis, including acute pyogenic meningitis, acute lymphocytic meningitis, and chronic meningitis. Acute pyogenic meningitis is caused by bacteria and results in inflammation of the meninges around the brain. Common causative organisms vary with age. Acute lymphocytic meningitis is usually viral and has milder symptoms that resolve more quickly. Chronic meningitis includes tuberculous and cryptococcal types, which cause long-term granulomatous inflammation that may lead to hydrocephalus. Diagnosis is based on examination of cerebrospinal fluid characteristics.
Meningitis
This document discusses meningitis, including causes, symptoms, diagnosis, and treatment. Meningitis is an inflammation of the membranes surrounding the brain and spinal cord caused by bacteria, viruses, fungi or parasites. Common bacterial causes include Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. Symptoms include fever, headache, stiff neck and confusion. Diagnosis involves lumbar puncture and examining cerebrospinal fluid. Treatment involves antibiotics and managing increased intracranial pressure. Prevention focuses on isolation, chemoprophylaxis for contacts, and vaccination.
Bacterial meningitis
summary of Bacterial meningitis
Describe the properties, transmission and pathogenesis of
Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae
as causative agents of meningitis.
BACTERIAL MENINGITIS BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE CHIN...
BACTERIAL MENINGITIS BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE CHIN...Prof Dr Bashir Ahmed Dar
Meningitis is an infection of the protective membranes (meninges) surrounding the brain and spinal cord. It is usually caused by bacteria, viruses, or fungi. The disease is contagious and can spread through respiratory and fecal-oral routes. Common symptoms include headache, fever, and neck stiffness. Bacterial meningitis requires prompt antibiotic treatment to prevent serious complications like brain damage.Meningitis
Module: Pharmacology and Therapeutics III, (Therapeutics part)
Coordinator: Dr. Arwa M. Amin Mostafa
Academic Level: Undergraduate, B.Pharmacy
School: Dubai Pharmacy College
Year of first presented in Class: 2018
This presentation is for Educational purpose. It has no commercial value associated with it.
Bacterial meningitis
This document summarizes bacterial meningitis. It is an inflammation of the meninges caused by bacteria entering the bloodstream from infections like pneumonia or ear infections. The most common types are pneumococcal, meningococcal, Hib, and listeria. Symptoms include high fever, severe headache, stiff neck, and confusion. Treatment involves intravenous antibiotics and managing complications. Prevention focuses on immunizations, hand washing, and food safety.
Meningitis Powerpoint
Meningococcal meningitis is an inflammation of the membranes covering the brain and spinal cord caused by the Neisseria meningitidis bacterium. Symptoms include intense headache, fever, stiff neck, and confusion or coma. Infants may only show irritability, tiredness, or poor feeding. Diagnosis is made through spinal fluid tests and treatment requires immediate antibiotics and hospitalization. Vaccines can prevent certain strains of the disease.
Meningitis
Acute bacterial meningitis is a medical emergency characterized by infection of the membranes surrounding the brain and spinal cord. The classic triad of symptoms includes fever, headache, and neck stiffness. Common causative organisms vary by age but include Streptococcus pneumoniae in about 50% of cases. Diagnosis involves lumbar puncture and CSF analysis showing elevated white blood cells, low glucose, and high protein levels. Treatment involves prompt administration of antibiotics like third generation cephalosporins and vancomycin before diagnostic tests. Outcomes depend on causative organism and presence of complications like seizures, altered mental status, and increased intracranial pressure.
Viral meningitis
This document summarizes various types of viral meningitis. The most common causes are enteroviruses, which account for over 75% of cases. Symptoms include headache, photophobia, and neck stiffness. Cerebrospinal fluid analysis typically shows lymphocytic pleocytosis. Treatment is supportive, with analgesics and antipyretics. Recovery is usually full. Rare causes include herpes simplex virus 2, arboviruses, mumps virus, and Epstein-Barr virus. Mollaret's meningitis is a recurrent form of aseptic meningitis believed to be caused by herpes virus. Chronic meningitis lasting over 4 weeks can be infectious or non-infectious.
22 Purulent Meningitis
Purulent meningitis is a serious infectious disease of the central nervous system that is most common in infants and children. The causative bacteria vary depending on the patient's age. Common bacteria include meningococci, hemophilus influenzae, and pneumococci. Purulent meningitis presents with nonspecific systemic symptoms along with signs of meningeal irritation and increased intracranial pressure. Diagnosis involves analysis of cerebrospinal fluid which shows neutrophilic pleocytosis, elevated proteins and low glucose. Complications can include subdural effusions, seizures, hydrocephalus and ventriculitis. Treatment involves initial broad-spectrum antibiotics targeting the common bacteria, followed by pathogen-directed therapy for
Meningitis
Meningitis is an inflammation of the membranes (meninges) surrounding the brain and spinal cord. It can be caused by bacteria, viruses, fungi or parasites. Bacterial meningitis is the most dangerous form and can cause death within hours if not treated promptly with antibiotics. Symptoms include sudden onset of fever, headache and stiff neck. Those at highest risk include adolescents, young adults living in dorms, infants, and people with certain medical conditions. While the disease is contagious through respiratory and mouth secretions, vaccination provides protection against some common types. Proper hygiene and promptly treating infections can also help prevent meningitis.
Bacterial meningitis amiri
This document discusses bacterial meningitis. It introduces the disease and common causative agents such as Streptococcus pneumoniae, Haemophilus influenzae, and Listeria monocytogenes. It notes the incidence is about 5 per 100,000 people per year in developed countries and around 200 cases per year in Kuwait. The clinical presentation typically includes headache, neck stiffness, fever, and altered mental status. Diagnosis involves blood and cerebrospinal fluid tests and neuroimaging may be required if certain symptoms are present.
Medicine 5th year, 5th lecture/part two (Dr. Mohammed Tahir)
The document discusses different types of central nervous system (CNS) infections including meningitis (bacterial, viral, fungal), encephalitis (bacterial, viral), and abscesses. It provides details on common causative agents of bacterial meningitis at different ages. Symptoms include fever, headache, vomiting and altered mental status. Signs include meningeal signs and increased intracranial pressure. Treatment depends on the identified causative organism and may include antibiotics, antivirals, or antitubercular medications. Chronic or recurrent meningitis can be caused by persistent infection, malignancy or non-infectious inflammatory disorders.
Encephalitis meningitis
The document discusses meningitis and encephalitis. It defines meningitis as an inflammation of the protective membranes covering the brain and spinal cord, known as the meninges. There are various causes of meningitis including bacterial, viral, parasitic and non-infectious. Common symptoms include headache, fever and neck stiffness. Diagnosis involves spinal fluid analysis and imaging. Treatment depends on the cause but may include antibiotics, antivirals or antifungals. Encephalitis additionally involves inflammation of the brain tissue and can be caused by viruses, bacteria, parasites and fungi. It presents with fever and neurological symptoms. Treatment focuses on the underlying cause and management of symptoms.
Meningitis and its management
Meningitis is an inflammation of the meninges that can be caused by bacterial, viral, fungal or parasitic infections. Bacterial meningitis is the most common and can be life-threatening if not treated promptly with antibiotics. Symptoms include headache, fever, neck stiffness, nausea and altered mental status. Diagnosis involves lumbar puncture, culture and analysis of cerebrospinal fluid. Treatment focuses on identifying the causative organism and administering the appropriate antibiotics, antivirals or antifungals. Outcomes depend on early diagnosis and treatment, with sequelae including hearing loss, neurological deficits, and death.
Meningitis
Meningitis is an inflammation of the protective membranes covering the brain and spinal cord. It can be caused by bacteria, viruses, fungi, or certain drugs. Common symptoms include fever, headache, and neck stiffness. Diagnosis involves examining cerebrospinal fluid obtained via lumbar puncture. Treatment involves immediate antibiotics, steroids, and other drugs depending on the cause. Complications can include brain damage, hearing loss, and death if not treated promptly.
Meningitis audrey perotti
Meningitis is an inflammation of the membranes surrounding the brain and spinal cord. It can be caused by various bacteria, viruses, and fungi. Bacterial meningitis requires immediate medical treatment with antibiotics to prevent permanent damage or death. Symptoms include headache, fever, and neck stiffness. While meningitis is most common in sub-Saharan Africa, outbreaks can occur anywhere. Vaccines exist for some causes of bacterial meningitis.
Meningitis
This document provides an overview of meningitis, including its causes, symptoms, diagnosis, and management. It discusses the different types of meningitis such as bacterial, viral, fungal, and non-infectious meningitis. The most common causes of bacterial meningitis are Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, and Listeria monocytogenes. Viral meningitis is generally less severe but can still be fatal depending on factors like the virus and patient's immune status. Diagnosis involves blood tests, lumbar puncture of cerebrospinal fluid, and determining markers like C-reactive protein level. Prompt treatment with antibiotics
More Related Content
What's hot
Meningitis jose ramonjoyanes-jorgegonzalez
Meningitis is an infectious disease that causes inflammation of the membranes surrounding the brain and spinal cord. It can be caused by viruses or bacteria found in the nose and throat. Common symptoms include high fever, severe headache, stiff neck, vomiting, and confusion. While most cases are mild and caused by viruses, bacterial meningitis can be life-threatening if not treated promptly with antibiotics. Vaccines exist to help prevent some common types of bacterial meningitis. Diagnosis involves examining cerebrospinal fluid through a lumbar puncture procedure.
Meningitis
Meningitis is an inflammation of the protective membranes (meninges) surrounding the brain and spinal cord. It is usually caused by a viral or bacterial infection. The meninges have three layers (dura mater, arachnoid mater, and pia mater) that are separated by fluid-filled spaces. Meningitis is a medical emergency because it can be life-threatening. It most commonly affects children and young adults. Bacterial meningitis is usually preceded by a mild respiratory infection that allows bacteria to enter the bloodstream and meninges. Diagnosis involves examination of cerebrospinal fluid obtained via lumbar puncture for signs of infection.
Meningitis
Meningitis is an inflammation of the protective membranes covering the brain and spinal cord caused most commonly by viral and bacterial infections. It can be life-threatening if not treated properly. The symptoms include headache, neck stiffness, fever, and sensitivity to light. A lumbar puncture of the cerebrospinal fluid is required for diagnosis. Treatment involves antibiotics for bacterial meningitis and supportive care, while prevention focuses on vaccination programs.
Cns infections Lecture
The document outlines key information about infections of the central nervous system, including various bacterial, viral, protozoal and fungal infections that can cause meningitis or encephalitis. It discusses the typical presentation, symptoms, diagnostic evaluation and treatment of different types of meningitis and how they vary depending on the causative pathogen and patient age.
Meningitis
This document discusses different types of meningitis, including acute pyogenic meningitis, acute lymphocytic meningitis, and chronic meningitis. Acute pyogenic meningitis is caused by bacteria and results in inflammation of the meninges around the brain. Common causative organisms vary with age. Acute lymphocytic meningitis is usually viral and has milder symptoms that resolve more quickly. Chronic meningitis includes tuberculous and cryptococcal types, which cause long-term granulomatous inflammation that may lead to hydrocephalus. Diagnosis is based on examination of cerebrospinal fluid characteristics.
Meningitis
This document discusses meningitis, including causes, symptoms, diagnosis, and treatment. Meningitis is an inflammation of the membranes surrounding the brain and spinal cord caused by bacteria, viruses, fungi or parasites. Common bacterial causes include Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. Symptoms include fever, headache, stiff neck and confusion. Diagnosis involves lumbar puncture and examining cerebrospinal fluid. Treatment involves antibiotics and managing increased intracranial pressure. Prevention focuses on isolation, chemoprophylaxis for contacts, and vaccination.
Bacterial meningitis
summary of Bacterial meningitis
Describe the properties, transmission and pathogenesis of
Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae
as causative agents of meningitis.
BACTERIAL MENINGITIS BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE CHIN...
BACTERIAL MENINGITIS BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE CHIN...Prof Dr Bashir Ahmed Dar
Meningitis is an infection of the protective membranes (meninges) surrounding the brain and spinal cord. It is usually caused by bacteria, viruses, or fungi. The disease is contagious and can spread through respiratory and fecal-oral routes. Common symptoms include headache, fever, and neck stiffness. Bacterial meningitis requires prompt antibiotic treatment to prevent serious complications like brain damage.Meningitis
Module: Pharmacology and Therapeutics III, (Therapeutics part)
Coordinator: Dr. Arwa M. Amin Mostafa
Academic Level: Undergraduate, B.Pharmacy
School: Dubai Pharmacy College
Year of first presented in Class: 2018
This presentation is for Educational purpose. It has no commercial value associated with it.
Bacterial meningitis
This document summarizes bacterial meningitis. It is an inflammation of the meninges caused by bacteria entering the bloodstream from infections like pneumonia or ear infections. The most common types are pneumococcal, meningococcal, Hib, and listeria. Symptoms include high fever, severe headache, stiff neck, and confusion. Treatment involves intravenous antibiotics and managing complications. Prevention focuses on immunizations, hand washing, and food safety.
Meningitis Powerpoint
Meningococcal meningitis is an inflammation of the membranes covering the brain and spinal cord caused by the Neisseria meningitidis bacterium. Symptoms include intense headache, fever, stiff neck, and confusion or coma. Infants may only show irritability, tiredness, or poor feeding. Diagnosis is made through spinal fluid tests and treatment requires immediate antibiotics and hospitalization. Vaccines can prevent certain strains of the disease.
Meningitis
Acute bacterial meningitis is a medical emergency characterized by infection of the membranes surrounding the brain and spinal cord. The classic triad of symptoms includes fever, headache, and neck stiffness. Common causative organisms vary by age but include Streptococcus pneumoniae in about 50% of cases. Diagnosis involves lumbar puncture and CSF analysis showing elevated white blood cells, low glucose, and high protein levels. Treatment involves prompt administration of antibiotics like third generation cephalosporins and vancomycin before diagnostic tests. Outcomes depend on causative organism and presence of complications like seizures, altered mental status, and increased intracranial pressure.
Viral meningitis
This document summarizes various types of viral meningitis. The most common causes are enteroviruses, which account for over 75% of cases. Symptoms include headache, photophobia, and neck stiffness. Cerebrospinal fluid analysis typically shows lymphocytic pleocytosis. Treatment is supportive, with analgesics and antipyretics. Recovery is usually full. Rare causes include herpes simplex virus 2, arboviruses, mumps virus, and Epstein-Barr virus. Mollaret's meningitis is a recurrent form of aseptic meningitis believed to be caused by herpes virus. Chronic meningitis lasting over 4 weeks can be infectious or non-infectious.
22 Purulent Meningitis
Purulent meningitis is a serious infectious disease of the central nervous system that is most common in infants and children. The causative bacteria vary depending on the patient's age. Common bacteria include meningococci, hemophilus influenzae, and pneumococci. Purulent meningitis presents with nonspecific systemic symptoms along with signs of meningeal irritation and increased intracranial pressure. Diagnosis involves analysis of cerebrospinal fluid which shows neutrophilic pleocytosis, elevated proteins and low glucose. Complications can include subdural effusions, seizures, hydrocephalus and ventriculitis. Treatment involves initial broad-spectrum antibiotics targeting the common bacteria, followed by pathogen-directed therapy for
Meningitis
Meningitis is an inflammation of the membranes (meninges) surrounding the brain and spinal cord. It can be caused by bacteria, viruses, fungi or parasites. Bacterial meningitis is the most dangerous form and can cause death within hours if not treated promptly with antibiotics. Symptoms include sudden onset of fever, headache and stiff neck. Those at highest risk include adolescents, young adults living in dorms, infants, and people with certain medical conditions. While the disease is contagious through respiratory and mouth secretions, vaccination provides protection against some common types. Proper hygiene and promptly treating infections can also help prevent meningitis.
Bacterial meningitis amiri
This document discusses bacterial meningitis. It introduces the disease and common causative agents such as Streptococcus pneumoniae, Haemophilus influenzae, and Listeria monocytogenes. It notes the incidence is about 5 per 100,000 people per year in developed countries and around 200 cases per year in Kuwait. The clinical presentation typically includes headache, neck stiffness, fever, and altered mental status. Diagnosis involves blood and cerebrospinal fluid tests and neuroimaging may be required if certain symptoms are present.
Medicine 5th year, 5th lecture/part two (Dr. Mohammed Tahir)
The document discusses different types of central nervous system (CNS) infections including meningitis (bacterial, viral, fungal), encephalitis (bacterial, viral), and abscesses. It provides details on common causative agents of bacterial meningitis at different ages. Symptoms include fever, headache, vomiting and altered mental status. Signs include meningeal signs and increased intracranial pressure. Treatment depends on the identified causative organism and may include antibiotics, antivirals, or antitubercular medications. Chronic or recurrent meningitis can be caused by persistent infection, malignancy or non-infectious inflammatory disorders.
Encephalitis meningitis
The document discusses meningitis and encephalitis. It defines meningitis as an inflammation of the protective membranes covering the brain and spinal cord, known as the meninges. There are various causes of meningitis including bacterial, viral, parasitic and non-infectious. Common symptoms include headache, fever and neck stiffness. Diagnosis involves spinal fluid analysis and imaging. Treatment depends on the cause but may include antibiotics, antivirals or antifungals. Encephalitis additionally involves inflammation of the brain tissue and can be caused by viruses, bacteria, parasites and fungi. It presents with fever and neurological symptoms. Treatment focuses on the underlying cause and management of symptoms.
Meningitis and its management
Meningitis is an inflammation of the meninges that can be caused by bacterial, viral, fungal or parasitic infections. Bacterial meningitis is the most common and can be life-threatening if not treated promptly with antibiotics. Symptoms include headache, fever, neck stiffness, nausea and altered mental status. Diagnosis involves lumbar puncture, culture and analysis of cerebrospinal fluid. Treatment focuses on identifying the causative organism and administering the appropriate antibiotics, antivirals or antifungals. Outcomes depend on early diagnosis and treatment, with sequelae including hearing loss, neurological deficits, and death.
Meningitis
Meningitis is an inflammation of the protective membranes covering the brain and spinal cord. It can be caused by bacteria, viruses, fungi, or certain drugs. Common symptoms include fever, headache, and neck stiffness. Diagnosis involves examining cerebrospinal fluid obtained via lumbar puncture. Treatment involves immediate antibiotics, steroids, and other drugs depending on the cause. Complications can include brain damage, hearing loss, and death if not treated promptly.
What's hot (20)
BACTERIAL MENINGITIS BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE CHIN...
BACTERIAL MENINGITIS BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE CHIN...
Medicine 5th year, 5th lecture/part two (Dr. Mohammed Tahir)
Medicine 5th year, 5th lecture/part two (Dr. Mohammed Tahir)
Similar to Meningitis
Meningitis audrey perotti
Meningitis is an inflammation of the membranes surrounding the brain and spinal cord. It can be caused by various bacteria, viruses, and fungi. Bacterial meningitis requires immediate medical treatment with antibiotics to prevent permanent damage or death. Symptoms include headache, fever, and neck stiffness. While meningitis is most common in sub-Saharan Africa, outbreaks can occur anywhere. Vaccines exist for some causes of bacterial meningitis.
Meningitis
This document provides an overview of meningitis, including its causes, symptoms, diagnosis, and management. It discusses the different types of meningitis such as bacterial, viral, fungal, and non-infectious meningitis. The most common causes of bacterial meningitis are Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, and Listeria monocytogenes. Viral meningitis is generally less severe but can still be fatal depending on factors like the virus and patient's immune status. Diagnosis involves blood tests, lumbar puncture of cerebrospinal fluid, and determining markers like C-reactive protein level. Prompt treatment with antibiotics
Introduction to Meningitis for Medical Students
Meningitis is an inflammation (swelling) of the protective membranes covering the brain and spinal cord. A bacterial or viral infection of the fluid surrounding the brain and spinal cord usually causes the swelling. However, injuries, cancer, certain drugs, and other types of infections also can cause meningitis. It is important to know the specific cause of meningitis because the treatment differs depending on the cause.
4 Meningitis 2012.pptx.ppt
Meningitis is an inflammation of the protective membranes (meninges) surrounding the brain and spinal cord. It is usually caused by a viral or bacterial infection, and can be life-threatening if not treated promptly. Common symptoms in adults include severe headache, fever, and neck stiffness. Diagnosis involves examination for signs of meningismus like Brudzinski's sign and Kernig's sign, and spinal fluid analysis. Prompt treatment with antibiotics or antivirals is required to prevent serious complications like brain damage.
Meningitis presentation CHOs 2023 Finals.pptx
Meningitis is an inflammation of the protective membranes covering the brain and spinal cord. It is usually caused by a viral or bacterial infection and can be life-threatening if not treated promptly. The symptoms of meningitis vary depending on the age of the patient but may include severe headache, fever, neck stiffness, nausea, confusion, and petechial rash. A lumbar puncture is required to diagnose meningitis by examining the cerebrospinal fluid for elevated white blood cells, low glucose levels, and high protein levels. Early diagnosis and treatment of the cause is important to prevent serious complications.
Meningitis
Meningitis is inflammation of the thin tissue that surrounds the brain and spinal cord, called the meninges. There are several types of meningitis. The most common is viral meningitis, which you get when a virus enters the body through the nose or mouth and travels to the brain. Bacterial meningitis is rare, but can be deadly. It usually starts with bacteria that cause a cold-like infection. It can block blood vessels in the brain and lead to stroke and brain damage. It can also harm other organs. Pneumococcal infections and meningococcal infections can cause bacterial meningitis.
Anyone can get meningitis, but it is more common in people whose bodies have trouble fighting infections. Meningitis can progress rapidly. You should seek medical care quickly if you have:
-- A sudden fever
-- A severe headache
-- A stiff neck
Describe the transmission of the meningococcus, and discuss the path.pdf
Describe the transmission of the meningococcus, and discuss the pathogenesis of meningococcal
disease in the body including associated signs and symptoms.
Solution
Transmission:
Meningococcal disease is caused by the bacterium Neisseria meningitidis.Meningococcal disease
is spread from person to person.The bacteria are spread by exchanging respiratory and throat
secretions such as saliva or spit,during close or lengthy contact,especially if living in the same
household.The bacteria are not spread by casual contact or by simply breathing the air where a
person with meningococcal disease has been.Sometimes bacteria spread to people who have had
close or lengthy contact with a patient with meningococcal disease.People in the same
household,roommates,or anyone with direct contact with a patient\'s oral secretions would be
considered at increased risk of getting the infection.
Pathogenesis:
Meningococcal disease causes life-threatening meningitis and sepsis conditions.In the case of
meningitis,bacteria attack the lining between the brain and skull called the meninges.The
meninges begin to swell and affects the central nervous system.The sepsis type of infection is
more deadly,and results in a severe blood poisoning called meningococcal sepsis which affects
the entire body.In this,bacterial toxins rupture blood vessels and can rapidly shut down vital
organs.Within hours,patient\'s health can change from seemingly good to mortality.
This bacterium is surrounded by a slimy outer coat that contains disease-causing endotoxin. The
levels of endotoxin produced by meningococcal bacteria are 100 to 1,000 times greater than
normal.As the bacteria multiply and move through the bloodstream,it sheds concentrated
amounts of toxin.The endotoxin directly affects the heart,reducing its ability to circulate
blood,and also build pressure on blood vessels throughout the body such that some blood vessels
start to hemorrhage,major organs like the lungs and kidneys gets damaged.Patients suffering
from meningococcal disease are treated with a large dose of antibiotic.The systemic antibiotic
flowing through the bloodstream rapidly kills the bacteria but,as the bacteria are killed,even
more toxin is released.It takes many days for the toxin to get neutralised from the body by using
treatment.
Signs and symptoms: The most common symptoms are a stiff neck,high fever,sensitivity of light
,confusion, headaches and vomitings.Bacterial meningitis may result in brain damage,hearing
loss or a learning disability.Meningococcal septicaemia is characterized by a haemorrhagic rash
and rapid circulatory collapse..
Lect 4 Infections of the Central Nervous system.pptx
The document discusses infections of the central nervous system (CNS). It describes the key causes as bacteria, fungi and viruses. It categorizes CNS infections as meningitis, encephalitis, or brain abscess. For meningitis, the document outlines the most common bacterial causes in children and adults, including Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae, Group B Streptococcus, Escherichia coli, and Listeria monocytogenes. It provides details on symptoms, diagnosis and treatment for each.
Bacterial meningitis
Bacterial meningitis is an infection of the meninges caused by bacteria such as Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae, and Listeria monocytogenes. It can cause inflammation of the tissues surrounding the brain and spinal cord. Symptoms include headache, fever, stiff neck and photophobia. While it can be life threatening, many patients recover if treated early with antibiotics. Vaccines exist to help prevent certain strains but prompt medical care is still important for treatment.
Pbl 3 –pod 1 : the morphology and structure of Neisseria meningitidis, the tr...
Pbl 3 –pod 1 : the morphology and structure of Neisseria meningitidis, the tr...imam univarsity , college of medicine .
Objective :
describe the morphology and structure of Neisseria meningitidis
describe the transmission and clinical features of meningitides
describe the process of development of meningitides
what is the diagnostic test required for Neisseria meningitidis
list the other causes of meningitis and its cfc finding
done by : asem shadid , college of medicine .Kuliah 19 Alam Sekitar Dan Je, Meningitis
The document discusses meningitis and Japanese encephalitis. It provides details on meningitis including what it is, common causes like meningococcal bacteria, symptoms, groups affected, and importance of vaccination. It notes that two students from UPM died from meningitis in 2002. The document also briefly mentions an outbreak of meningitis in China in 2005 that killed 8 people.
Meningitis
This document provides information on meningitis, including:
1. It describes the anatomy of the meninges and cerebrospinal fluid production and circulation.
2. It identifies the most common causes of meningitis as viral and bacterial infections and lists specific viruses and bacteria that can cause meningitis.
3. It outlines the clinical manifestations of meningitis such as headache, fever, neck stiffness, altered mental status, and seizures. Complications like increased intracranial pressure and brain damage are also discussed.
2. Meningitis diseses of the brain membrane.pptx
The meninges, which cover the brain and spinal cord, become inflamed in meningitis. Bacterial meningitis is more severe and can cause death or brain damage if untreated. Viral meningitis is usually mild and self-limiting. A lumbar puncture collects cerebrospinal fluid which can be analyzed to distinguish between bacterial and viral meningitis and identify the specific cause. Common symptoms include headache, fever, and neck stiffness, while signs include Kernig's sign and Brudzinski's sign.
Meningitis
Meningitis is an infection of the membranes (meninges) surrounding the brain and spinal cord. It can be caused by bacteria, viruses, or fungi. Bacterial meningitis is the most common and life-threatening type. Symptoms include fever, severe headache, nausea, and neck stiffness. Diagnosis involves spinal fluid analysis to identify the cause. Treatment focuses on antibiotics, steroids, and managing increased intracranial pressure. Complications may include hearing loss, learning difficulties, and seizures. Prevention involves vaccination and prompt treatment of infections.
Meningitis
This document provides information on meningitis, including:
- Meningitis is an inflammation of the meninges (membranes covering the brain and spinal cord) that can be caused by bacteria, viruses, fungi, or other causes.
- Common symptoms include fever, headache, and neck stiffness.
- Bacterial meningitis requires immediate treatment with antibiotics to prevent disability or death. Viral meningitis is generally less severe but still requires supportive care.
- Complications can include hearing loss, seizures, learning difficulties, and even death if not properly treated.
Nervous conditions 1.pdf
This document provides information on meningitis, including its causes, signs and symptoms, diagnostic evaluation, and management. It begins by defining meningitis as an inflammation of the meninges caused by various infectious microorganisms or non-infectious etiologies. The major causes are categorized as infective, including bacteria (such as Neisseria meningitidis and Streptococcus pneumoniae), viruses, fungi, and parasites, or non-infective such as cancers or autoimmune disorders. Clinical presentation varies depending on age but may include headache, fever, vomiting, seizures, and neck stiffness. Diagnosis involves lumbar puncture for cerebrospinal fluid analysis along with imaging and lab tests. Management is
meningitis_20240308_230236_0000nursing.pdf
Meningitis is an inflammation of the meninges, the protective membranes covering the brain and spinal cord. It is commonly caused by bacterial, viral, or fungal infections, leading to symptoms like fever, headache, stiff neck, and sensitivity to light. The meninges are made up of three layers (dura mater, arachnoid mater, and pia mater) that cover and protect the brain and spinal cord. Pathogens can enter the meninges through the bloodstream or nearby infections and cause inflammation. This inflammation puts pressure on the brain and can impair brain function if not promptly treated.
9 менингококковая инфекция англ.ppt
1) Meningococcal infection is an acute infectious disease caused by the bacterium Neisseria meningitidis, which can cause nasopharyngitis, meningitis, meningoencephalitis, or meningococcemia.
2) It is transmitted through respiratory droplets and can range from localized infection to severe systemic disease. Common symptoms include fever, headache, neck stiffness, and a petechial rash.
3) Diagnosis involves examination of cerebrospinal fluid which shows increased pressure, cloudiness, and a high number of neutrophils. Treatment requires immediate antibiotic therapy and supportive care for complications like shock. Early diagnosis and treatment are important for recovery.
MENINGITIS.ppt
Meningitis is an inflammation (swelling) of the protective membranes covering the brain and spinal cord. A bacterial or viral infection of the fluid surrounding the brain and spinal cord usually causes the swelling. However, injuries, cancer, certain drugs, and other types of infections also can cause meningitis.
Bacterial meningitis
The document discusses bacterial meningitis, providing information on the anatomy of the meninges, causes of meningitis including bacterial, viral and fungal infections. It describes the typical presentation of bacterial meningitis including symptoms like headache, fever and neck stiffness. Complications are outlined such as subdural effusions, ependymitis and hydrocephalus. Causative organisms and their prevalence are summarized for different age groups.
Similar to Meningitis (20)
Describe the transmission of the meningococcus, and discuss the path.pdf
Describe the transmission of the meningococcus, and discuss the path.pdf
Lect 4 Infections of the Central Nervous system.pptx
Lect 4 Infections of the Central Nervous system.pptx
Pbl 3 –pod 1 : the morphology and structure of Neisseria meningitidis, the tr...
Pbl 3 –pod 1 : the morphology and structure of Neisseria meningitidis, the tr...
More from Mehak AggarwAl
nanoparticles-and-their-medical-applications.pptx
Nanoparticles have various types and sizes that determine their medical applications. Gold and silver nanoparticles are used in imaging and drug delivery due to their optical properties. Iron oxide nanoparticles are used as MRI contrast agents because they alter the relaxation times of water protons under magnetic fields.
in-vitro-in-vivo-correlation-
The document discusses the results of a study on the effects of a new drug on memory and cognitive function in older adults. The double-blind study involved giving either the new drug or a placebo to 100 volunteers aged 65-80 over a 6 month period. Testing showed those receiving the drug experienced statistically significant improvements in short-term memory retention and processing speed compared to the placebo group.
DRUG ABSORPTION FROM GASTROINTESTINAL TRACT
MPHARMACY PHARMACEUTICS 2 SEMESTER
ADVANCED BIOPHARMACEUTICS AND PHARMACOKINETICS
UNIT 1 DRUG ABSORPTION FROM GASTROINTESTINAL TRACT
MECHANISM OF DRUG ABSOPTION
role-of-dosage-form-in-gastrointestinal-absorption.pptx
mpharmacy pharmaceutics 2 semester
advanced biopharmaceutics andpharmacokinetics
unit 1 Gastrointestinal absorption: role of the dosage form
viral-and-non-viral-gene-transfer.pptx
mpharmacy 2 semester pharmaceutics
molecular pharmaceutics
unit 5 viral and non viral gene transfer - gene expression systems
liposomal-gene-delivery-system.pptx
Liposomal gene therapy is a promising new approach for treating disease. It works by using liposomes, which are spherical vesicles made of phospholipids, to deliver therapeutic genes directly to cells. The liposomes protect the DNA from degradation and promote cellular uptake of the genes, allowing for expression of therapeutic proteins and potential correction of genetic defects.
biopharmaceutics-of-antisense-molecule-and-aptamers.pptx
Antisense molecules and aptamers are two types of biopharmaceuticals that can be used to treat diseases. Antisense molecules work by binding to messenger RNA to prevent translation into proteins, while aptamers are short strands of nucleic acids or peptides that bind to target molecules with high affinity and specificity. These biopharmaceuticals show promise for developing new therapies and require consideration of their absorption, distribution, metabolism, and excretion to determine clinical effectiveness and safety.
Targeted drug delivery system
M.pharm (Pharmaceutics) Molecular Pharmaceutics (NTDS) unit 1 part 1 Targeted Drug Delivery Systems: Concepts, Events and biological process involved in drug targeting.
Tumour targeting and brain specific drug delivery
m.pharm pharmaceutics 2 semester molecular pharmaceutics (NTDS) unit 1 Tumour targeting and Brain specific drug delivery
Usfda
The US Food and Drug Administration (USFDA) is a government agency responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices, cosmetics, animal foods and feed. The USFDA is part of the United States Department of Health and Human Services.
Hipaa
The Health Insurance Portability and Accountability Act (HIPAA) establishes national standards to protect sensitive patient health information and ensures the security and privacy of health data. It addresses the use and disclosure of individuals' health information and the rights that individuals have to understand and control how their health information is used. HIPAA seeks to strike a balance that permits important uses of information while protecting the privacy of people who seek care and healing.
Nonclinical drug development
regulatory affairs m.pharm pharmaceutics - Non clinical drug development: Global submission of IND, NDA, ANDA.
Investigation of medicinal products dossier, dossier (IMPD) and investigator brochure (IB)
Study of consolidation parameters
M.pharm (Pharmaceutics) modern pharmacy unit-5 Study of consolidation parameters; Diffusion parameters, Dissolution
parameters and Pharmacokinetic parameters, Heckel plots, Similarity factors – f2
and f1, Higuchi and Peppas plot, Linearity Concept of significance, Standard
deviation , Chi square test, students T-test , ANOVA test
Validation part 2
m.pharm (pharmaceutics) modern pharmaceutics- unit 2 validation- part 2 Validation of specific dosage form,
Types of validation. Government regulation, Manufacturing Process Model,
URS, DQ, IQ, OQ & P.Q. of facilities.
Validation
M.pharm (Pharmaceutics) Modern Pharmaceutics unit- Validation Part-1 introduction, scope and merits of validation, Validation and calibration of Master plan, ICH & WHO guidelines for calibration and validation of equipment.
Compression and compaction
1) Tablet compression involves the application of force to reduce the volume of powder materials through three main processes: compression, compaction, and consolidation. Compression removes air, compaction rearranges particles, and consolidation increases strength through bonding.
2) Key forces involved in compression include inter-particulate and die wall friction, which can be reduced by adding glidants and lubricants, respectively. Distribution forces transmit pressure from the punches to the powder bed and die wall.
3) Compaction profiles examine the relationship between axial and radial pressure. They provide information on elastic versus plastic deformation and ejection forces.
Osmotic activated drug delivery system
This document provides an overview of osmotic activated drug delivery systems. It begins with an introduction that explains osmotic pressure is used to release drugs in a controlled manner from these systems. The basic components, advantages, and disadvantages are then outlined. Several types of osmotic pumps are described in detail, including how they work and their applications. In summary, this document serves as a comprehensive review of osmotic drug delivery systems, their design principles, and performance characteristics.
Enzyme activated drug delivery systems
This document discusses enzyme-activated drug delivery systems. It describes how enzymes can directly release drugs from carriers upon site-specific cleavage or facilitate drug release by generating products that alter carrier properties. Typical enzymes discussed include matrix metalloproteinases, phospholipases, and oxidoreductases. Popular carrier approaches activated by enzymes are polymeric nanoparticles, liposomes, and hybrid inorganic/organic nanoparticles. The document provides examples of how each carrier type can be designed to respond to specific enzymes and selectively release drugs.
P h activated drug delivery systems
m.pharm unit 2 rate controlled drug delivery systems- pH activated drug delivery sytems- nanoparticles, hydrogels, microspheres, microgels
Mechanically activated drug delivery system
m.pharm (pharmaceutics) unit 2 rate controlled drug delivery system- mechanically activated drug delivery system
More from Mehak AggarwAl (20)
role-of-dosage-form-in-gastrointestinal-absorption.pptx
role-of-dosage-form-in-gastrointestinal-absorption.pptx
biopharmaceutics-of-antisense-molecule-and-aptamers.pptx
biopharmaceutics-of-antisense-molecule-and-aptamers.pptx
Recently uploaded
Top Effective Soaps for Fungal Skin Infections in India
Swisschem Dermacare has mentioned the List of The Best Antifungal Soap In India 2022. All of these soaps are trusted by various Dermatology Experts.
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
All info about Diabetes and how to control it.
One health condition that is becoming more common day by day is diabetes.
According to research conducted by the National Family Health Survey of India, diabetic cases show a projection which might increase to 10.4% by 2030.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Role of Mukta Pishti in the Management of Hyperthyroidism
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Ketone bodies and metabolism-biochemistry
This slide consists of all the topics of ketone . This can be used for exam purpose for writing about Diabetic keto acidosis etc . Thank you
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
LOOPS in orthodontics t loop bull loop vertical loop mushroom loop stop loop
vertical loop
horizontal loop
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Recently uploaded (20)
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Role of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of Hyperthyroidism
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
LOOPS in orthodontics t loop bull loop vertical loop mushroom loop stop loop
LOOPS in orthodontics t loop bull loop vertical loop mushroom loop stop loop
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Meningitis
- 2. Introduction Definition- serious inflammation of meninges. ● Infection due to bacteria, viruses, fungi, bleeding of meninges, cancer, disesase of immune system. ● It affects delicate brain. ● Due to this brain cells will not regenerate. ● Brain tissues are damaged by infect. ● Affects the functioning of dura mater, arachnoid mater and pia mater , the cerebrospinal fluids. ● Brain skull donot expand and hence swollen brain tissues push up against hard skull bone. ● Tissues got damaged and ultimately die.
- 3. Continued….. ● Blood-Brain Barrier. -- ● Capillaries don't allow substances from entering into brain tissues. ● Helps to prevent various poisonous and toxins to enter the brain.
- 4. Causes and symptoms. There are two type of causes. 1. Non-bacterial 2. Bacterial ● Non-bacterial are common cause of meningitis. ● Meningitis caused due to bacteria is life threatening. ● Bacteria- Haemophilus influenzae ● Neissrria meningitidis ● Streptococci pneumoniae
- 5. Other causes ● Mumps and measeles virus ● Chicken pox, rabies virus, infected mosquito bite . ● Person suffering from AIDS. ● Blood-prone diseases. ● Lungs, throat, or tissues of heart infection. ● Person suffering from skull fracture.
- 6. Symptoms Fever, headache, vomiting, sensitivity to light, irritability, severe fatigue, stiff neck, raddish purple rash on skin, seizures, confusion, eventually coma.
- 10. ● Antibiotics like penicillin and cephalosporin can be given. ● Antifungal and NSAID’s can also be given.
- 11. Thank you 🙏