X-rays are generated when accelerated electrons interact with a metal target, producing X-ray beams that are passed through the body and absorbed at different rates by tissues depending on their density. The X-rays that pass through the body expose silver halide film, creating an image where bone and other dense tissues appear lighter since they absorb more X-rays. Contrast agents can enhance the visualization of similar tissues. CT scans use X-rays and a computer to generate cross-sectional images of the body, while MRI uses magnetic fields and radio waves to produce detailed images of soft tissues without radiation exposure. Bone scans and PET scans use radioactive tracers to detect bone abnormalities and areas of increased metabolic activity. DEXA scans measure bone
This slide best explains the introduction of CT, basis and types of CT image reconstructions with detailed explanation about Interpolation, convolution, Fourier slice theorem, Fourier transformation and brief explanation about the image domain i.e digital image processing.
This slide best explains the introduction of CT, basis and types of CT image reconstructions with detailed explanation about Interpolation, convolution, Fourier slice theorem, Fourier transformation and brief explanation about the image domain i.e digital image processing.
Medical imaging is the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology).
Lec2: Digital Images and Medical Imaging ModalitiesUlaş Bağcı
2017 Spring, UCF Medical Image Computing Course
X-ray?
• Ultrasound?
• ComputedTomography(CT)?
• MagneticResonanceImaging(MRI)?
• PositronEmissionTomography(PET)? • DiffusionWeightedImaging(DWI)?
• DiffusionTensorImaging(DTI)?
• MagneticParticleImaging(MPI)?
• OpticalCoherenceTomography(OCT)?
Basics of Radiological Image Modalities and their clinical use (MRI, PET, CT, fMRI, DTI, ...) • Introduction to Medical Image Computing and Toolkits • Image Filtering, Enhancement, Noise Reduction, and Signal Processing • MedicalImageRegistration • MedicalImageSegmentation • MedicalImageVisualization • Machine Learning in Medical Imaging • Shape Modeling/Analysis of Medical Images Deep Learning in Radiology
Image reconstruction in CT is mostly a mathematical process however, this presentation tries to explain the complicated process of image reconstruction in a visual way, mainly focusing om Filtered back projection, Iterative Reconstruction and AI based image reconstruction.
Medical imaging is the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology).
Lec2: Digital Images and Medical Imaging ModalitiesUlaş Bağcı
2017 Spring, UCF Medical Image Computing Course
X-ray?
• Ultrasound?
• ComputedTomography(CT)?
• MagneticResonanceImaging(MRI)?
• PositronEmissionTomography(PET)? • DiffusionWeightedImaging(DWI)?
• DiffusionTensorImaging(DTI)?
• MagneticParticleImaging(MPI)?
• OpticalCoherenceTomography(OCT)?
Basics of Radiological Image Modalities and their clinical use (MRI, PET, CT, fMRI, DTI, ...) • Introduction to Medical Image Computing and Toolkits • Image Filtering, Enhancement, Noise Reduction, and Signal Processing • MedicalImageRegistration • MedicalImageSegmentation • MedicalImageVisualization • Machine Learning in Medical Imaging • Shape Modeling/Analysis of Medical Images Deep Learning in Radiology
Image reconstruction in CT is mostly a mathematical process however, this presentation tries to explain the complicated process of image reconstruction in a visual way, mainly focusing om Filtered back projection, Iterative Reconstruction and AI based image reconstruction.
CT scan and MRI are the techniques for body imaging. Computed Tomography or Computerized Axial Tomography is commonly referred to as a CT scan.
C- computed (Use of computer) and T- tomography (Greek word “Tomos” means “slice” and “Grapho” means “ To write”
The first commercial CT scanner was invented by Sir Godfrey Hounsfield in United Kingdom.
It is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce images of the inside of the body. It shows detailed images of any part of the body including the bones, muscles, fat, organs and blood vessels.
CT scans may be performed to help diagnose tumors, investigate internal bleeding, or check for other internal injuries or damage.
Computed Tomography or Computerized Axial Tomography is commonly referred to as a CT scan.
C- computed (Use of computer) and T- tomography (Greek word “Tomos” means “slice” and “Grapho” means “ To write”
The first commercial CT scanner was invented by Sir Godfrey Hounsfield in United Kingdom.
It is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce images of the inside of the body. It shows detailed images of any part of the body including the bones, muscles, fat, organs and blood vessels.
CT scans may be performed to help diagnose tumors, investigate internal bleeding, or check for other internal injuries or damage. Computed Tomography or Computerized Axial Tomography is commonly referred to as a CT scan.
C- computed (Use of computer) and T- tomography (Greek word “Tomos” means “slice” and “Grapho” means “ To write”
The first commercial CT scanner was invented by Sir Godfrey Hounsfield in United Kingdom.
It is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce images of the inside of the body. It shows detailed images of any part of the body including the bones, muscles, fat, organs and blood vessels.
CT scans may be performed to help diagnose tumors, investigate internal bleeding, or check for other internal injuries or damage. MRI stands for Magentic Resonance Imaging which is a non-invasive medical imaging test that produces detailed images of almost every internal structure in the human body, including the organs, bones, muscles and blood vessels.
MRI scanners create images of the body using a large magnet and radio waves.
No ionizing radiation is produced during an MRI exam, unlike X-rays. These images give your physician important information in diagnosing your medical condition and planning a course of treatment.
Raymond Damadian, the inventor of the first magnetic resonance scanning machine performed the first full-body scan of a human being in 1977.
The Nobel Prize was awarded to the American chemist, Paul Lauterbur, and the British physicist, Peter Mansfield, for developing a method to represent the information gathered by a scanner as an image. This is fundamental for the way the technology is used today.
Second year PG Resident of I Q City Medical College and Hospital, Durgapur, West Bengal.
Covers the scope and use of Imaging technology in Orthopaedics.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. X- Rays
• X-rays are generated from the interaction of accelerated e-
’s & a target metal (tungsten)
• Patient is placed between X-ray tube and silver halide film
• X-rays passed through the body are absorbed in direct proportion to tissue density
• X-rays penetrating the body strike the silver halide film and turn it dark
• The more x-rays that penetrate, the darker the area inscribed on the film
• Bones & metal absorb or reflect X-rays rinscribed film is “lighter” or “more white”
• Soft tissues allow more X-rays to penetrate rinscribed film is “darker”
• Visualizing tissues of similar density can be enhanced using “contrast agents”
• Contrast agents: dense fluids containing elements of high atomic number (barium, iodine)
• Contrast agents absorbs more photons than the surrounding tissue r cavity appears lighter
• These contrast agents can be injected, swallowed, or given by enema
electron beam generator
tungsten target metal
resultant X-ray beam
silver halide film
2. X-ray View of a
Gunshot Wound
(Bullet has split into
fragments)
3. For Emma…..
We Will Always Remember !!
Normal Breast
Breast with Cysts
and Fibrotic
Changes
Breast Cancer !
X-Ray Mammography
4. Classic X-ray view of
“Lung Infiltrates” caused
by Pneumonia. Notice the
increased “whiteness”
close to the sternum
5. X-ray view of broken ribs in an infant ….
……caused by child abuse. Specifically, by holding the
baby by the chest and shaking him violently.
6. • The scanner device incorporates a moving table & a revolving X-ray tube
• The table moves the patient back and forth through the revolving X-ray emissions
• The X-ray emitter moves (revolves) in a 360o
arc around the patient
• Instead of film, the CT scanner collects emitted X-rays via a collector
• This collector is called a SCINTILLATOR
• Scintillator transforms X-ray’s into a proportionally strong electric current
• The electric current is then converted into a number of images (“slices”)
• Contrast dyes may be used for image enhancement
• Tool of choice for most stroke cases
Computed Tomography (“CT Scan” or “Cat Scan”)
13. Magnetic Resonance Imaging
• Magnetic nuclei are abundant in the human body (H,C,Na,P,K) and spin randomly
• Since most of the body is H2O, the Hydrogen nucleus is especially prevalent
• Patient is placed in a static magnetic field
• Magnetized protons (spinning H nuclei) in the patient align in this field like compass needles
• Radio frequency (RF) pulses then bombard the magnitized nuclei causing them to flip around
• The nuclei absorb the RF energy and enter an excited state
• When the magnet is turned off, excited nuclei return to normal state & give off RF energy
• The energy given off reflect the number of protons in a “slice” of tissue
• Different tissues absorb & give off different amounts of RF energy (different resonances)
• The RF energy given off is picked up by the receiver coil & transformed into images
• MRI offers the greatest “contrast” in tissue imaging technology (knee, ankle diagnosis)
• cost: about $1450 - $2000
• time: 30 minutes - 2 hours, depending on the type of study being done
Open MRIClosed (traditional) MRI scanner
14. Magnetic Resonance Imaging
tissues composition & signal intensity
Tissue Signal Intensity T1 Signal Intensity T2
Fat high (whitish) intermediate
Muscle intermediate (gray) intermediate
Hyaline Cartilage intermediate intermediate - low (dull gray)
Ligaments & Tendons low (dark gray) low
Cortical Bone low low
Granulation Tissue intermediate high
Fibrous Tissue low low
Hemorrhage / Edema high - intermediate high
Immature Scar intermediate - low low to high
Mature Scar low low
16. Normal ACL
(note “darker” region
indicating normality)
Grade 3 ACL tear
(note “lighter” region where the
“darker” region used to be.
This indicates tissue disruption
and associated fluid buildup)
17. MRI view of the
same Ischemic
Stroke seen in
slide 8
18. Bone Scan
• Measures the rate of bone formation
• Any disease that injures bone will cause new bone to form
• This process is a very sensitive measure of bone disease processes
• Often used for detecting cancer mets (breast, prostate), fractures, & infection
• Can be used to detect avascular necrosis of bone
• Procedure is done by injecting a technetium labeled phosphate (raidioactive)
• Pictures are taken using a gamma camera……
• Immediately after injection, 3 hours post injection, & 24 hour post injection
• Dose of radiation is small
• Takes about an hour to complete
20. Positron Emission Tomography
(PET) Scan
• Device measures metabolism via the decay of
radioactive tracers in tissues with higher than
normal metabolic activity (such as cancer)
• Patient is injected with FluorDeoxyGlucose
• Glucose bound to Fluorine 18 (radioactive)
• Diseased organs & tissues process FDG at
a higher rate than normal tissues making
FDG concentration higher in diseased
tissue
• Positrons are emitted by FDG and collide
with electrons, emitting radiation
• Radiation picked up by camera
• Computer reconstructs the radioactivity
into 3 dimensional images of organ or area
with higher than normal FDP uptake
• Procedure performed as outpatient
• Takes about 2 hours
• Results available to physician within 48 hours
22. PET Scan showing Non Hodgkins Lymphoma (Green
Arrows) before & after 6 months of chemotherapy
23. Dual Energy X-ray Absoprtometry (DXA or DEXA)
• Used to test for bone mineral density (BMD) ie. Osteoperosis
• Thin X-ray beam is passed through the hip and lower spine regions
• Computer calculates how much X-ray energy is absorbed by the bones
• Computer compares results with an average 20 year old (T-score) and an
average age, race and gender peer (Z-score)
• Results are plotted on a norm graph and given to the radiologist
24. Dual Energy X-ray Absoprtometry (DXA or DEXA)
GE LUNAR Prodigy DEXA...in the
Applied Exercise Science Lab
Our new toy!
26. T-score (sd’s)
(WHO standard reference)
Fracture Risk Medical Action
Normal Test: T > -1.0 Low Lifestyle advice
dBone Mass: T -1.0 to -2.5
(Possible Osteopenia)
Above Average
Lifestyle advice, HRT in
women 50 – 60 , Calcium
and Vitamin D
supplementation
Osteoperosis: T < -2.5 High
All of above plus consider
Bisphosphonate Drugs
(FOSOMAX, ACTINEL….)
Established Osteoporosis
plus the occurrence of one
or more fractures
Very High
All of above plus consider
possible pain control and
referral to specialist
DEXA Standards